• Health Policy and Management
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• v.25 no.4
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• pp.323-332
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• 2015

Background: Antibiotic resistance has been becoming serious challenge to human beings. Overuse of antibiotics, especially, for infants is concerned, but studies are very few for the prescribing pattern of antibiotic use for infants. This study analyzes prescribing patterns of antibiotics in outpatients of preschool children with acute respiratory tract infections in South Korea. Methods: Data are used from 2011 Health Insurance Review & Assessment Services-pediatric patients sample. Inclusion criteria is outpatient children (0 to 5 years) with top five frequent diseases. Prescription rates are analyzed by types of disease, provider, specialty, region, and ages. Binary or multinomial logit models are used to analyze determinants of providers' prescription pattern. Results: The main findings are as follows. First, distributions of prescription rates are shown as L-shape or M-shape depending on the types of disease. Second, the prescription variation is so large among providers, where providers are polarized as a group with low prescription rates and the other group with high prescription rates, though the shapes are shown diversified across types of disease. Third, prescription rates appear to be lower in pediatrics and higher in ENT (ear-nose-throat). Fourth, broad spectrum antibiotics are widely used among children. Finally, the logit analysis shows similar results with descriptive statistics, but partly different results across types of disease. Conclusion: Antibiotics for respiratory tract infections of infants are used excessively with a large variation among providers, and especially broad spectrum antibiotics are used. The prescription guideline for antibiotics should be provided for each specific disease to reduce antibiotic resistance in the future.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1282-1291
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• 2009

A combined prescription of GGB and CHS (G&C prescription group) was used to investigate its effects on immune related factors and histological changes in atopic dermatitis(AD) induced mice. Significant decrease of atopic dermatitis clinical index in G&C prescription group. In DLN, G&C prescription group significantly modulated the immune cells. G&C prescription group also showed significant effect on the immune cells of the dorsal skin as well as DLN. The group indicated significant decrease of the biosynthesis of IL-4, IL-5, IL-13, GM-CSF, cytokines in serum. On the other hand, the biosynthesis of TNF-$\alpha$ was decreased. G&C prescription group significantly decreased the immunoglobulin IgE levels in serum. The results suggest that G&C prescription significantly improves atopic dermatitis through regulation of immune cells and cytokines. Comparative studies with Protopic ointment also showed that G&C prescription showed significant effect in AD patients, and active application of the prescription in clinicals is anticipated. However, the reason for the results that oppose to those of previous studies should be investigated. Also, therapeutic effects of both internal and external applications should be studied individually as well as for any synergistic effects. Safety, toxicity, as well as stability studies should follow to develop G&C prescription into long-term external clinical product.

• Journal of Korean Medical classics
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• v.20 no.1
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• pp.65-74
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• 2007

"The Golden Mirror of Medicine(醫宗金鑑)" was compiled by the medical officers of the Qing government, headed by Wu-Qian(吳謙)."The Elimination &Supplement about the Famous Prescription Comments(刪補名醫方論)", a collection of notes written by famous scholars, is one part of "The Golden Mirror of Medicine(醫宗金鑑)" . Through the translation and comparative study of invigorative prescription(補氣方劑) in "The Elimination & Supplement about the Famous Prescription Comments(刪補名醫方論)" of "The Golden Mirror of Medicine(醫宗金鑑)" with "The Famous Prescription Comments on Ancient and Modem Times(古今名醫方論)" , we confirmed that many sentences of "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)" were quoted, but that most of the text was not quoted as the same: it was revised and supplemented. In organization, invigoration prescriptions are placed at the head of the chapter, indicating their importance. In classification, prescriptions for reinforcing middle-jiao(中焦) and replenishing qi(補中益氣湯類 方劑) were usually included in the invigoration prescriptions(補氣方劑), which is explained in chapter II, thereby clearly distinguishing between treatments of deficiency of qi(氣虛) and combining it with the sinking of qi of middle-jiao(中氣下陷).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.158-176
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• 2014

Purpose : The purpose of this study is to investigate the effect of ARTEMISIAE CAPILLARIS HERBA and COPTIDIS RHIZOMA Extracts on cell death in pancreatic cancer cells. Method : Human-derived pancreatic cancer cell line, MIA PaCa-2 cells were treated by Prescription A with various concentrations and the cytotoxicity was determined by MTT assay. To investigate the effects of Prescription A on pancreatic cancer cells, the staining of Annexin V/PI, cell cycle arrest, nuclear chromatin condensation and the production of reactive oxygen species (ROS) were examined. The effect of Prescription A's effective components, ARTEMISIAE CAPILLARIS HERBA and COPTIDIS RHIZOMA Extracts on cell death were also observed. Results : The viability of MIA PaCa-2 cells treated with Prescription A were decreased in a dose dependent manner. Prescription A induced cell death in MIA PaCa-2 cells as shown by result of Annexin V/PI double staining, chromatin condensation and cell cycle arrest. In addition, production of ROS was increased by Prescription A treatment, suggesting that ROS induced by Prescription A mediated cell death. Furthermore, Prescription A's effective components, ARTEMISIAE CAPILLARIS HERBA and COPTIDIS RHIZOMA Extracts were also induced apoptosis of MIA PaCa-2 cells through ROS production. Conclusion : These results suggest that Prescription A's effective components, ARTEMISIAE CAPILLARIS HERBA and COPTIDIS RHIZOMA Extracts induced death of MIA PaCa-2 through ROS production.

• Health Policy and Management
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• v.2 no.2
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• pp.131-151
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• 1992

The contents of prescription service were comparatively analysed between health centers(HC) and private clinics(PC). Medical chart review was done for 330 otu-patients diagnosed with upper respiratory tract infection(UR) of 120 adults and 90 children, and gastritis or duodenitis of 120 adults. Emphasis on comparison was the prime cost of medication which used in prescription service. The results were as follows; 1. The prime costs fro the medication per visit of HC group were significantly higher than PC group in all three diseases, and the out of pocket payments of patients per visit were significantly lower in the HC group than PC group. 2. The reason for high prime costs of medication per visit of HC in adult case of URI were due to the idverse use of medication and long prescription period per visit. And high medication costs in children cases of URI in HC group were due to the longer prescription day. In cases of gastritis, the prime cost of medication was also higher because of longer prescription period and the higher prime cost of medication. The proportions of medications for injection in the HC and PC groups showed similar features. 3. In depth analysis of the prescription services showed the differences of the contents of medication. In adults cases of URI, the averaged cost of oral medication was significantly lower in HC group, but that of medication for injection was higher in HC group. In children cases of URI, the averaged cost of oral medication and medication for injection was lower in HC group than in PC group. But in the cases of gastritis it was was higher in HC group than in PC group. The prescription periods were longer in HC group than in PC group in all three diseases. As a conclusion prime medication cost and quality of prescription services of HC group were higher than PC group. In terms of health care the cost containment and quality assurance in physician visit for common disease, public sector utilization is good option for those perspectives. But it should not be generalized unless future study about structure and outcome research for quality assurance.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.1
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• pp.153-166
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• 2010

Objectives : The aim of this study is to make proof of availability for Sanghanron prescription. Methods : The study group comprised 80 Koreans, male:female ratio of 31:49, with mean age of 40.78 years. The SF-MPQ and PDI were checked hospitalized and discharged patients. Results : 1. The most uesd prescription is Galgeun-Tang(Gegen-tang) and the other 30 prescriptions were uesd. 2. Hospitalized patients, there was significant difference in SF-MPQ and PDI scores(P<0.05). 3. The treatment was effective to 72 patients out of 80 who had been hospitalized for less than 14 days. 4. Experimental group compared with Lee's thesis was significantly difference in 7 days of treatment, but the other compared were not significant difference. Conclusions : This data suggested that the Sanghanron prescription could be effective treatment about traffic accidental patients without surgical injury. Further study is needed about the effectiveness of Sanghanron prescription.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.07a
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• pp.121-122
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• 2016

본 논문에서는 청소년 비만에 대한 심각성이 증가함에 따라 더욱 체계적인 관리를 위해 줄넘기에 ICT 기술을 접목시켜 개인에게 알맞은 맞춤형 운동프로그램을 제안한다. 이 정책은 개별성의 원리에 의하여 개인차를 고려한 운동 프로그램을 설정하여 개개인들의 욕구, 흥미, 그리고 능력을 향상시키는데 있다. 이때 운동프로그램 설정을 못하는 운동초보자들을 위하여 줄넘기에 내장된 센서가 체력수준을 인식하고 그에 알맞은 프로그램을 제공하여 보다 효과적인 신체능력을 향상시켜 준다는 것에 의의를 두고 있다.

• Journal of Korean Medical classics
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• v.26 no.4
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• pp.1-21
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• 2013

Objective : This study is about how theory on seven kinds of prescriptions in Yellow Emperor's Cannon of Internal Medicine(黃帝內經) had been developed and how it had been applied for in prescription books or clinical texts. Method : I made a comparison of this theory between prescription books and clinical texts. After it, I investigated the change or development of it. Result : The first explanation about this was made by Wang Bing(王氷). Yu Wanso(劉完素) made up several varieties and meanings of it, Jang Jahwa(張子和) corrected what Yu Wanso added. Besides, someone for example, Wang Hogo(王好古), Yi Cheon(李梴), and so on added new varieties and meanings of odd prescription and even prescription. Conclusion : Theory on seven kinds of prescriptions in Yellow Emperor's Cannon of Internal Medicine had been constantly changed and developed in prescription books or clinical texts.

• Journal of Fisheries and Marine Sciences Education
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• v.25 no.2
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• pp.307-320
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• 2013

The purpose of this study is to inquire into present conditions and problems of current performance test and to try to come up with a fundamental alternative of it. Eventually, the studies of performance test so far can be labelled 'prescription' as a prospective approach. On the contrary, the fundamental alternative can be labelled 'understanding' as a retrospective approach. It can be seen that these 'prescription' and 'understanding' do not separate but represent both extreme ends of problem-solving.'Prescription' exists for 'understanding' and the latter can be acquired through the former. Just under this assumption, it can be accepted that 'prescription' as a prospective approach of performance test is an inevitable measure to achieve the purpose of it. However, the ultimate purpose of 'prescription' should proceed to 'understanding' as a retrospective approach.

• Journal of Korean Medical classics
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• v.20 no.3
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• pp.33-48
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• 2007

Before the advent of febrile disease theory, people had used Sanghallon's theory to cure febril disease. Therefore, Wu-Tang both suggested new prescription and used the former prescription of Sanghallon(傷寒論) in curing febrile disease. However, he didn't use the original prescription of Sanghallon and modified the quantity and ingredients properly. Through this process, the fault of Sanghallon was supplemented and the method of curing febrile disease was advanced. To research about this, it will be much easier to understand prescription of Sanghallon and even the treatments and views of Wu-Tang about febrile disease. In this study, I researched the way Wu-Tang applied prescription of Sanghallon, focusing on Decoction for Purgation, White Tiger Decoction, Decoction for Restoring Pulse which was used by Wu-Tang in various ways and applied in treatment of febrile disease.