• 한국건설관리학회논문집
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• 제9권4호
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• pp.140-153
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• 2008

국내에서 건설기술경쟁력 제고를 위하여 기술개발에 대한관심이 높아지고 있으며, 이러한 관심과 더불어 공공과 민간에서 기술개발투자 확대를 위한 다양한 노력을 하고 있다. 이에 본 연구에서는 국가적인 차원에서 건설기술개발 촉진을 유도하기 위한 여러 가지 제도 가운데 PQ제도의 기술력 평가항목에 대한 분석을 수행하였으며, 이와 함께 PQ제도 이후의 특허출원 추이에 대한 다각적인 분석을 통한 PQ제도와 특허출원간의 상관관계를 파악하고자 수행하였다. 또한 향후 제도적 판단근거로의 사용과 건설업체들의 특허 및 실용신안 출원과 등록향상을 위해 현재 PQ제도와 기술개발의 제도적, 기능적 문제점분석을 토대로 지원방안 모색과 특히 특허 및 실용신안의 활용도를 높이기 위한 시사점을 도출하는데 그 주안점을 두었다. 이를 위해 국내 PQ제도의 기술평가항목 중 신기술과 특허에 대한 기술가점의 변화에 대한 추이분석을 수행하였으며, 국내 건설업체들의 특히 및 실용신안의 출원과 등록실태를 건설업체들의 특성별, 규모별로 구분하여 분석하였다. 이렇게 분석된 내용을 토대로 제도변화 추세에 따른 건설업체들의 기술개발 실태를 비교 분석하여 기술개발 및 활용상의 제도적, 기능적 문제점 분석을 통해 이에 따른 시사점을 도출하였다.

• 한국건설관리학회논문집
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• 제14권6호
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• pp.3-13
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• 2013

입찰참가자격 사전심사(Pre-Qualification: PQ)에 포함된 여러 평가항목 중, 신인도 항목에 포함된 환산재해율의 평가는 재해발생에 대한 결과에만 치중하고 있어 산재은폐, 공상처리 등의 부작용이 발생하고 있다. 따라서 기업의 적극적인 안전관리활동 및 재해예방에 대한 노력을 평가할 수 있는 사전평가지표의 개발이 요구되고 있다. 이에 본 연구는 사전평가지표 수립을 위한 기초자료의 제공을 목적으로 미국 LA 지역의 공공기관에서 적용하고 있는 PQ 심사 자료를 수집 분석하여 다양한 안전관련 평가내용을 파악하였다. 그 결과, LA 지역은 과거 프로젝트에서 발생한 재해뿐만 아니라 산재보험 및 재해발생 당시의 규정위반 여부 등 다양한 사후안전관련 평가를 실시하고 있으며, 기업의 안전교육 및 재해예방 프로그램, 안전관리 계획 등 사전안전관련 내용도 평가에 반영하고 있는 것으로 나타났다. 따라서 국내에서도 PQ심사에 환산재해율을 포함한 다양한 사후안전관련 평가와 함께 사전안전관련 평가지표를 수립하여 반영한다면, 기존 환산재해율의 기능을 강화함과 동시에 기업의 적극적인 안전관리활동을 유도하고, 나아가 건설산업의 재해율 감소를 기대할 수 있을 것으로 판단된다.

• Journal of Microbiology and Biotechnology
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• 제24권5호
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• pp.605-613
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• 2014

We have previously shown that paraquat (PQ)-induced oxidative stress causes dramatic damage in various human cell lines. Naringenin (NG) is an active flavanone, which has been reported to have beneficial bioactivities, including antioxidative, anti-inflammatory, and antitumorigenic activities, with a relatively low toxicity to normal cells. In this study, we intended to assess the cytoprotective effect of NG against PQ-induced toxicity in the human bronchial epithelial BEAS-2B cell line. Co-treatment with NG in PQ-treated BEAS-2B cells can reduce PQ-induced cellular toxicity. NG can also decrease the generation of intracellular ROS caused by PQ treatment. We also observed that treatment with NG in PQ-exposed BEAS-2B cells can significantly induce the expression of antioxidant-related genes, including GPX2, GPX3, GPX5, and GPX7. NG co-treatment can also activate the NRF2 transcription factor and promote its nuclear translocation. In addition, NG co-treatment can induce the expression of NRF2-downstream target genes such as that of heme oxygenase-1 (HO-1) and NAD(P)H:quinone oxidoreductase 1 (NQO1). A small interfering RNA study revealed that the knockdown of NRF2 can abrogate NG-mediated protection of the cells from PQ-induced cellular toxicity. We propose that NG effectively alleviates PQ-induced cytotoxicity in human bronchial epithelial BEAS-2B cells through the NRF2-regulated antioxidant defense pathway, and NG might be a good therapeutic candidate molecule in oxidative stress-related diseases.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.108-108
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• 2003

The current study was performed to observe the effects of Panax ginseng (PG) and P. quinquefolia (PQ) on hemodynamics such as blood flow rate (BF), blood flow velocity (BV), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP, and body temperature (BT) in healthy young men. After testing equality of variance, Student's t-test using PROC TTEST was examined to. prove statistical differences between control and ginseng conditions at each time point. It was found that the BF data were fluctuated by personal deviation. In order to minimize the deviation, the results obtained for 6 hrs were reconstituted after dividing them into two periods of the first half from 1 to 3 hrs and of the latter half from 3.5 to 6 hrs. And then the reconstitution data and dose-response curves were obtained. Blood flow such as BF and BV shows significant increases both two periods in the dose of PG 2.25 and PG 9.0, whereas significant decrease in the dose of PG 4.5. However, in the PQ groups, the middle dose PQ 4.5 shows the highest significant increase among the three doses. Except for PG 2.25 in HR, other doses show significant decreases both in the first half and latter half. SBP of PQ 9.0 shows only a significant decrease in the first half; on the other hand, in the latter half, PG 4.5, PG 9.0 and PQ 9.0 significantly increase SBP. In addition, DBP of PG 2.25 and PG 4.5 show significant increase in the both periods. In the BT, PQ groups show gradual decrease from PQ 2.25 to PQ 9.0; however, PG groups show differently. PG 4.5 shows significant decrease, but PG 9.0 shows a increase without statistical meanings. In summary, PG is more effective in respect to keeping homeostasis of hemodynamics.

• 한국소음진동공학회논문집
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• 제13권12호
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• pp.965-971
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• 2003

고밀도, 고정밀의 정보저장기를 실현하기 위해서 높은 서보대역이 요구되고 있다 이러한 요구조건을 만족시키기 위해서 이단구동시스템이 도입되었다. 이 시스템은 기존의 VCM을 조동구동기로, 추가적인 밀리엑츄에이터를 미동구동기로 사용하는 것이다. 이를 위해 우리는 압전형 밀리엑츄에이터를 서스펜션 부에 설계하였다 이러한 시스템의 제어를 위하여 PQ 제어 방법을 도입하였으며, 이 방식은 이중입력/단일출력 시스템을 두개의 단일 입출력 시스템으로 단순화시키는 것이다. 이 논문은 PQ 제어 방식을 적용시켜 설계하고. 설계된 제어기의 성능 평가로써 기존의 HDD의 PES을 받아서 외란제어 능력을 평가하는 것이다.

• 환경위생공학
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• 제14권2호
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• pp.8-17
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• 1999

This research employed a senescence-accelerated mouse(SAM) to explore the possibility that differences exist among the major antioxidatns, lipid peroxidation in terms of ability to protect such animal treatment PQ, SAM-R/1 and SAM-P/8 were administered with PQ(200ppm/Kg) orally. The toxicity of PQ on SAM was determined as a bioassays of SOD, catalase and lipid peroxidation in the mouse liver. The data show that the SOD activity was induced by paraqwuat terement in both SAM-R/1 and SAM-P/8. The degree of lipid peroxidation was increased with PQ treatment. This means that SOD rather than catalase may protect against oxygen radical toxicity. Finally, over data lead to the toxicity of PQ and its function may efect to the antioxidants including SOD, catalase and lipid peroxidation in both SAM-R/1 and SAM-P/8 .

• Journal of Electrical Engineering and Technology
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• 제10권1호
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• pp.92-101
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• 2015

As one type of power quality (PQ) disturbance sources, high-speed rail (HSR) can have major impacts on the power supply grid. Providing timely and accurate warning information for PQ problems of HSR is important for the safe and stable operation of traction power supply systems and the power supply grid. This study proposes a novel warning approach to identify PQ problems and provide warning prompts based on the monitored data of HSR. To embody the displacement and status change of monitored data, multi-features of different sliding windows are computed. To reflect the relative importance degree of these features in the overall evaluation, an analytic hierarchy process (AHP) is used to analyse the weights of multi-features. Finally, a multi-features similarity algorithm is applied to analyse the difference between monitored data and the reference data of HSR, and PQ warning results based on dynamic thresholds can be analysed to quantify its severity. Cases studies demonstrate that the proposed approach is effective and feasible, and it has now been applied to an actual PQ monitoring platform.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제12권1호
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• pp.42-46
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• 2012

With the development of industry, more large-scale non-linear loads are added to existing power systems and they cause the serious power quality (PQ) problems to the nearby sensitive installations more and more. To protect the important loads and mitigate the impact of PQ disturbances on them, various compensating devices are installed. One of the most important control skills used in the compensating equipment at the load side is how fast they can recognize or detect the discontinuous abnormal PQ events from the normal voltage signal. This paper deals with two estimation methods for the fast detection and tracking of general PQ disturbances: Teager Energy Operator (TEO), which is a non-linear operator and used for a short time energy calculation, and Kalman Filter (KF), which is one of the most universally used estimation techniques. And it is also shown how to apply the TEO and the KF to detect the PQ disturbances such as voltage sag, swell, interruption, harmonics and voltage fluctuation.

• The Plant Pathology Journal
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• 제20권1호
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• pp.75-80
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• 2004

In an attempt to develop effective biocontrol system for management of stem rot disease in groundnut, 57 bacterial isolates and 13 isolates of Trichoderma spp. were evaluated for their antagonistic activity against Sclerotium rolfsii. The antagonists were selected based on their ability to inhibit the external growth of S. rolfsii from infected groundnut seeds. Four isolates of Pseudomonas fluorescens, GB 4, GB 8, GB 10 and GB 27, and T. viride pq 1 were identified as potent antagonists of S. rolfsii. T. viride pq 1 produced extracellular chitinase and parasitized the mycelium of S. rolfsii. Under controlled environment conditions, P. fluorescens GB 10, GB 27, T. viride pq 1 and the systemic fungicide Thiram(equation omitted) reduced the mortality of S. rolfsii inoculated to groundnut seedlings by 58.0％, 55.9％, 70.0％ and 25.9％, respectively compared to control. In vitro growth of P. fluorescens GB 10 and GB 27 was compatible with T. viride pq 1 and Thiram(equation omitted). Integrated use of these two bacterial isolates with T. viride pq 1 or Thiram(equation omitted) improved their biocontrol efficacy. Combined application of either GB 10 or GB 27 with T. viride pq 1 was significantly effective than that with Thiram(equation omitted) in protecting groundnut seedlings from stem rot infection.

• 전력전자학회논문지
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• 제8권6호
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• pp.527-533
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• 2003

최근 민감한 전자부하의 사용증대에 기인하여 전직의 안정도와 신뢰도에 대한 관심이 증대되고 있다. 이에 전력풀질문제가 근래에 있어 일반적인 중요한 과제로 대두되었다. 이러한 전력품질문제를 진단하기 위하여 실효치나 FFT 등의 기법을 이용한 많은 알고리즘이 연구되어 왔으나 모든 전력품질문제를 진단하기에는 아직도 미진한 상황이다. 본 논문은 이산 웨이블릿을 응용한 전력품질문제의 진단 방법을 제안하고 웨이블릿의 이론에 대한 기본적인 설명과 함께 제안된 이론의 타당성을 입증하기 위하여 실제 전력품질문제 진단시스템을 설계하고 실험결과를 제시하였다.