• 제목/요약/키워드: PPA

검색결과 111건 처리시간 0.02초

지상기준점을 이용한 비측량용 카메라 렌즈 캘리브레이션 (Non-Metric Digital Camera Lens Calibration Using Ground Control Points)

  • 원재호;소재경;윤희천
    • 한국측량학회지
    • /
    • 제30권2호
    • /
    • pp.173-180
    • /
    • 2012
  • 최근 비약적인 기술발전을 통해 8,000만 화소급 디지털 카메라가 등장했으며, 비측량용 디지털 카메라가 사진 측량 분야에서 다양하게 활용되고 있다. 본 연구에서는 항공사진과 지상기준점을 이용하여 렌즈 캘리브레이션을 수행하였다. 항공사진은 35mm 렌즈가 장착된 CMOS 2,110만 화소급 비측량용 디지털 카메라를 헬리콥터에 설치하여 취득하였고, 지상기준점은 1:1,000 도화원도에서 선점하였다. 그 결과 렌즈에 대한 초점거리, PPA, 방사왜곡계수를 계산할 수 있었다. 또한 렌즈 캘리브레이션 전후에 항공삼각측량을 수행하여 지상기준점의 평균제곱근오차와 최대 잔차를 비교하였으며, 캘리브레이션 후 정확도가 매우 큰 폭으로 향상됨을 알 수 있었다.

Preparation of Controlled Release Spheronized Beads by a Simple Extrusion and Modified Spheronization Process

  • Lee, Si-Beum;Kim, Min-Soo;Jun, Seoung-Wook;Park, Jeong-Sook;Hwang, Sung-Joo
    • Archives of Pharmacal Research
    • /
    • 제28권5호
    • /
    • pp.619-625
    • /
    • 2005
  • Beads loaded with the water-soluble drug, phenylpropanolamine HCl (PPA), were prepared using an extruder and double arm counter-rotating roller modified from a traditional pill machine. The mean diameter of the cylindrical rod-like extrudate from the ram extruder was 3 mm; that of the uncoated bead after cutting and spheronization by the modified double arm counter-rotating roller was 3.26~3.28 mm. Although the surface of the beads was moderately rough and irregular, some exhibited hump-shaped protrusions, the sphericity was acceptable (roundness 1.15) and adequate for the subsequent coating process. An increase in mean diameter of the coated beads and improvements in friability and sphericity were observed in proportion to the amount of coating material applied (ethylcellulose or Eudragit?? RS 100). It was also found that the release rate of PPA from the coated beads could be controlled by the amount and type of coating materials applied or with the incorporation of Eudragit ?? RS 100 into the core matrix. Further modifications to the double arm counter-rotating roller, including adjustment of the rotation speed and distance between the rollers, would yield smaller uncoated beads with improved roundness and surface roughness. In conclusion , the present method could be potentially applied to prepare controlled release drug delivery beads or pellet dosage forms.

스키 시뮬레이터 운동 시 하지 운동특성 분석 및 관성센서 파라미터를 이용한 스키 숙련도 평가 (Kinematic Analysis of Lower Extremity and Evaluation of Skill of Skier Using Parameters of Inertial Sensors During Ski Simulator Exercise)

  • 김정윤;안순재;박선우;신이수;김규석;김영호
    • 대한의용생체공학회:의공학회지
    • /
    • 제35권3호
    • /
    • pp.35-41
    • /
    • 2014
  • In this study, joint angles of the lower extremity and inertial sensor data such as accelerations and angular velocities were measured during a ski simulator exercise in order to evaluate the skill of skiers. Twenty experts and twenty unskilled skiers were recruited for the study. All expert skiers held the certificates issued by the Korea Ski Instructors Association. A three-dimensional motion capture system and two inertial sensors were used to acquire joint movements, heel acceleration and heel angular velocity during ski simulator exercises. Pattern variation values were calculated to assess the variations in ski simulator motion of expert and unskilled skiers. Integral ratio of roll angular velocity was calculated to determine the parallel alignment of the two feet. Results showed that ski experts showed greater range of motion of joint angle, peak-to-peak amplitude(PPA) of heel acceleration and PPA of heel angular velocity than unskilled skiers. Ski experts showed smaller pattern variations than unskilled skiers. In addition, the integral ratio of roll angular velocity in ski experts was closer to 1. Inertial sensor data measurements during the ski simulator exercises could be useful to evaluate the skill of the skier.

생쥐에 있어서 약물의 혈액-뇌 관문 투과성 평가를 위한 간편한 in vivo 방법 (The Simple in Vivo Evaluation Method for Blood-Brain Barrier Permeability of Drugs in Mice)

  • 강영숙;김유정
    • Journal of Pharmaceutical Investigation
    • /
    • 제30권2호
    • /
    • pp.99-105
    • /
    • 2000
  • This study compared the permeability of $[^3H]taurine,\;[^3H]phenylalanine,\;and\;[^3H]oxytocin$ through the blood-brain barrier (BBB) in mice and rats with common carotid artery perfusion (CCAP) method that modified internal carotid artery perfusion (ICAP) method. External carotid artery (ECA) was cannulated with coagulating pterygopalatine artery (PPA) in ICAP method, while CCA was cannulated without coagulating PPA in CCAP method. Also, for evaluation of BBB permeability of drugs in mice and rats, we used intravenous injection technique. The results of CCAP method in mice at a perfusion flow-rate of 2 ml/min, the brian volume of distribution $(V_D)$ of $[^{14}C]sucrose,\;[^3H]taurine,\;[^3H]phenylalanine,\;and\;[^3H]oxytocin$ were similar to the result of ICAP method in rats at perfusion flow rate of 4 ml/min. The area under the plasma concentration-time curve and brain uptake of $[^3H]taurine$ by intravenous injection technique, were $65.5{\pm}9.7%ID^*min/ml\;and\;0.515{\pm}0.093%ID/g$, respectively, in mice, and the corresponding values were $8.00{\pm}0.03%ID^*min/ml\;and\;0.052{\pm}0.003%ID/g$ in rats. But the BBB permeability surface-area product of $[^3H]taurine$ was similar between mice and rats. In conclusion, the CCAP method in mice was simple, fast and comparable to ICAP method in rats for drug permeability through the BBB.

  • PDF

연료전지용 불소화 폴리벤즈이미다졸 양성자 교환 멤브레인 합성 및 특성평가 (Synthesis and Characterization of Fluorinated Polybenzimidazole Proton Exchange Membranes for Fuel Cell)

  • 김애란
    • 한국수소및신에너지학회논문집
    • /
    • 제28권1호
    • /
    • pp.24-29
    • /
    • 2017
  • A fluorinated polybenzimidazole (FPBI) was synthesized from 3,3-diaminobenzidine (DAB) of tetraamine, 2,2-bis(4-carboxyphenyl)hexafluoropropane of aromatic biscarboxylic acid, and 4,4-sulfonyldibenzoic acid of aromatic biscarboxylic acid in polyphosphoric acid (PPA). A FPBI was easily cast and made into clear films. The structure of condensation polymers and corresponding membranes were analyzed using GPC (gel permeation chromatography), $^1H$-NMR ($^1H$ nuclear magnetic resonance) and FT-IR (fourier transform infrared). TGA (thermogravimetric analysis) analysis showed that the prepared membranes were thermally stable, so that elevated temperature fuel cell operation would be possible. The proton conductivity of the FPBI membranes increased with increasing temperatures in the polymer. A FPBI membrane has a maximum ion conductivity of 45 mS/cm at $90^{\circ}C$ and 100% relative humidity.

새로운 5-Fluorobenzimidazole 항진균제의 합성과 생물학적 평가 (Synthesis and Biological Valutaion of New 5-Fluorobenzimidazole Antifungal Agents)

  • 류성렬
    • 한국응용과학기술학회지
    • /
    • 제28권1호
    • /
    • pp.118-125
    • /
    • 2011
  • New type of 5-fluorobenzimidazole derivatives was synthesized through the reaction of 4-fluoro-5-(2,6-dimethylmorpholinyl)-2-aminoaniline with 5-nitro-2-furoic acid and 5-methoxy-3-chlorobenzothiophene-2-carboxylic acid in presence of PPA and treatment of $OH^-$. the resulting substituted 5-fluorobenzimidazole derivatives(6), (7) was characterized by high solubility in common polar organic solvents. We considered 5-fluorobenzimidazole derivatives were useful especially for antifungal drugs. These results are discussed from the viewpoints of the chemical and physical structures of the 5-fluorobenzimidazole derivatives.

2자유도 평면 병진 병렬형 기구의 동역학 해석 (Dynamics Analysis of a 2-DOF Planar Translational Parallel Manipulator)

  • 팜벤백옥;김한성
    • 한국생산제조학회지
    • /
    • 제22권2호
    • /
    • pp.185-191
    • /
    • 2013
  • In this paper, the dynamics of a novel 2-DOF planar Translational Parallel Manipulator (TPM) is analyzed. The suggested TPM is made up of two PPa (Prismatic-planar Parallelogram) legs. Since all the linear actuators are mounted on the base, the proposed TPM can be applied for high speed positioning applications. The Lagrangian equations of the first type is employed to derive the inverse dynamic equations. It is shown that the analytical inverse dynamics equations match very well with ADAMS simulations. These analytical inverse dynamics equations will be used for the real-time computed torque control in the further work.

Partial Pole Assignment via Constant Gain Feedback in Two Classes of Frequency-domain Models

  • Wang, Guo-Sheng;Yang, Guo-Zhen;Duan, Guang-Ren
    • International Journal of Control, Automation, and Systems
    • /
    • 제5권2호
    • /
    • pp.111-116
    • /
    • 2007
  • The design problem of partial pole assignment (PPA) in two classes of frequency-domain MIMO models by constant gain feedback is investigated in this paper. Its aim is to design a constant gain feedback which changes only a subset of the open-loop eigenvalues, while the rest of them are kept unchanged in the closed-loop system. A near general parametric expression for the feedback gain matrix in term of a set of design parameter vectors and the set of the closed-loop poles, and a simple parametric approach for solving the proposed problem are presented. The set of poles do not need to be previously prescribed, and can be set undetermined and treated together with the set of parametric vectors as degrees of design freedom provided by the approach. An illustrative example shows that the proposed parametric method is simple and effective.

산처리된 활성탄소섬유의 Propylamine의 흡착특성 (Adsorption Characteristics of Propylamine on Acid Treated Activated Carbon Fiber)

  • 양범호;김병구;이영택;김시몽;조시형
    • 한국연초학회지
    • /
    • 제25권2호
    • /
    • pp.111-119
    • /
    • 2003
  • In this work, Rayon-based activated carbon fiber(KF-1500) was treated by HN $O_3$ and $H_2$S $O_4$ with different conditions. Specific surface areas(SSA, $S_{BET}$) of the treated activated carbon fibers were decreased by acidic treatment but, total surface acidities and surface functional groups were increased. In spite of the decrease of SSA, propylamin(PPA) adsorption and removal ability by activated carbon fiber(ACF) were increased by nitric acid treatment compared with the raw-ACF(KF-1500) and coconut based activated carbon. However, acidic treated activated carbon fibers were available to removal for various amines and contaminants by adsorption.n.

Catalytic Cyclopolymerization and Copolymerization of Diethyl Dipropargylmalonate by (toluene)Mo$(CO)_3

  • 전상진;심상철;조찬식;김태정;갈영순
    • Bulletin of the Korean Chemical Society
    • /
    • 제21권10호
    • /
    • pp.1044-1046
    • /
    • 2000
  • Catalytic copolymerization of diethyl dipropargylmalonate (DEDPM) and phenylacetylene (PA) by Mo(CO)6 and (toluene) Mo(CO)3/chloranil has resulted in the expected copolymer consiting of a polyene backbone with five-and/or six-membered rings and th e PPA structure. Both complexes exhibited not only varying degree of catalytic activity depending upon the relative mole ratio of two monomers but also characterize the types of coploymers. The former yields the polyene backbone containing only five-membered rings as well as PA while the latter produces the polymers consisting of both five-and six-membered ring structure. Comparative studies show that Mo(CO)6 exhibits reactivity toward DEDPM alone, thus catalyzing initially metathesis cyclopoly-merization of DEDPM followed by copolymerization with PA while the (toluene)Mo(CO)3/chloranil system shows affinity for both PA and DEDPM.