• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2023.11a
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• pp.166-168
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• 2023

기존 eLoran 수신기는 보정기준국(인천·평택항 반경 30km 이내에서만 이용 가능하며 ASF 맵보정 정보를 저장하는데 한계가 있음. 자체 오차정보를 보정하는 기능을 가진 eLoran/GPS 통합수신기의 알고리즘 및 성능 분석을 통해 더 넓은 해역에서 eLoran 서비스를 백업항법시스템으로 이용하기 위한 기반 마련

• Korean Institute of Interior Design Journal
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• v.25 no.6
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• pp.40-51
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• 2016

The aim of this study is to quantitatively deduce the circulation efficiency and space arrangements of the outpatient department in geriatric hospitals in terms of spatial structure and to find a methodology that could promote the improvement of accessibility and spatial cognition while using the facilities. All space units of the selected twelve geriatric hospitals were located on the first floor. The study adopted the psychological distance concept of space syntax to the unitized spaces, and presented a set of indices, such as TD, PN, RF, PNT and TRF. These indices were calculated according to the standard clinical use procedures. The study evaluated the effectiveness of circulation. The analysis of circulation was based on the four major geriatric illnesses that were selected in this study. The study established the standard clinical use procedure with consideration of the medical treatment, examinations and space units of outpatient departments. The results are as follows: 1) Based on the statistical data, four major geriatric illnesses are examined, and space requirement and standard procedures are established. Development indicators are applied in order to quantitatively deduce the efficiency of spatial cognition. 2) The percentage of the risk of cognitive decline(TRF) has an inversely proportional correlation to the circulation efficiency(PNT) at a certain point. TRF is more influenced by the clinical use procedure than the scale. 3) The arrangement of the waiting space and types of corridor greatly affect the percentage of the risk of cognitive decline. 4) Vulnerable facilities are selected on the basis of the evaluation, and two alternatives that could promote the circulation efficiency are presented. The result of the reanalysis showed that cognitive efficiency had much improved compared to the existing facilities.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.8
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• pp.1619-1625
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• 2017

Civil global navigation satellite system (GNSS) does not meet user performance requirements for specific PNT (Positioning, Navigation, and Time) applications. Therefore, various differential systems are used to augment GNSS for improving positioning accuracy and integrity. The MTSAT satellite augmentation system (MSAS) is the Japanese satellite based augmentation system. This paper is for analyzing the characteristics of Japanese MSAS in Korean peninsula. First of all, it was done for analyzing not only DGNSS navigation signal but also the navigation parameter through simulation and experimental tests. As a result of data analyses, the sufficient navigation satellites to determine 3-D position based on DGNSS are simultaneously available at MSAS monitering station and the southern region of Korean peninsula. It was verified that the carrier to noise signals are stable to maintain the reliable 3-D position and that the level of 2m (2drms) accuracy is very similar to the ordinary worldwide DGNSS as well.

• Journal of Ginseng Research
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• v.45 no.2
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• pp.273-286
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• 2021

Background: Prostate carcinoma is the second most common cancer among men worldwide. Developing new therapeutic approaches and diagnostic biomarkers for prostate cancer (PC) is a significant need. The Chinese herbal medicine Panax quinquefolius saponins (PQS) have been reported to show anti-tumor effects. We hypothesized that PQS exhibits anti-cancer activity in human PC cells and we aimed to search for novel biomarkers allowing early diagnosis of PC. Methods: We used the human PC cell line DU145 and the prostate epithelial cell line PNT2 to perform cell viability assays, flow cytometric analysis of the cell cycle, and FACS-based apoptosis assays. Microarray-based gene expression analysis was used to display specific gene expression patterns and to search for novel biomarkers. Western blot and quantitative real-time PCR were performed to demonstrate the expression levels of multiple cancer-related genes. Results: Our data showed that PQS inhibited the viability of DU145 cells and induced cell cycle arrest at the G1 phase. A significant decrease in DU145 cell invasion and migration were observed after 24 h treatment by PQS. PQS up-regulated the expression levels of p21, p53, TMEM79, ACOXL, ETV5, and SPINT1 while it down-regulated the expression levels of bcl2, STAT3, FANCD2, DRD2, and TMPRSS2. Conclusion: PQS promoted cells apoptosis and inhibited the proliferation of DU145 cells, which suggests that PQS may be effective for treating PC. TMEM79 and ACOXL were expressed significantly higher in PNT2 than in DU145 cells and could be novel biomarker candidates for PC diagnosis.

• Journal of Advanced Navigation Technology
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• v.27 no.4
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• pp.396-409
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• 2023

In the field of autonomous vehicles, where high accuracy and reliability are critical, various satellite navigation augmentation systems have been developed to improve system performance. These systems generate correction and integrity information based on measurements and navigation data collected from ground reference stations, enhancing user positioning accuracy. Thus, the performance of the system heavily relies on the deployment and spacing of reference stations. To construct an effective satellite navigation augmentation system, careful consideration must be given to the installation points of reference stations. This paper presents a user positioning performance modeling formula and proposes a method for selecting the installation points of new reference stations. The proposed method involves selecting a candidate group area that can optimize the user's positioning performance. By utilizing this method, the system's performance can be improved, ensuring high accuracy and reliability for autonomous vehicle applications.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.11a
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• pp.209-211
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• 2022

우리나라 R-Mode(Ranging Mode) 항법시스템은 국제해사기구(IMO, International Maritime Organization)에서 요구하는 항구 입출항용 항법 요구성능(정밀도 10m)을 만족하도록 개발을 진행하고 있다. R-Mode 항법시스템은 위성국 송출을 기반으로 하는 GPS와 달리 지상국 송출을 기반으로 한다. 또한 신호가 세기가 높아서 의도적 전파간섭이 어려우므로 국제해사기구가 요구하는 강인한 PNT(Resilient PNT) 시스템에 적합한 것으로 평가받고 있다. 이러한 요구조건과 기회신호(SoOp, Signal of Opportunity)의 국내 환경에 맞추어 중파(MF, Middle Frequency) 및 초단파(VHF, Very High Frequency)를 이용하는 항법시스템을 개발하고 있다. 해양수산부의 지원으로 2020년에 착수하여 4국의 중파 R-Mode 송신국과 3국의 초단파 VDES R-Mode 송신국 구축을 진행하고 있다. 항법 성능을 확보하기 위하여 R-Mode 보정시스템과 R-Mode 감시시스템을 구축하였다. 해양에서 R-Mode 항법시스템의 성능을 검증하기 위하여 중파 R-Mode 수신기, VDES R-Mode 수신기 및 이를 포함하는 통합항법수신기를 함께 개발하고 있다. 항법 송신기 및 수신기의 성능 검증을 위한 테스트베드는 기존의 지상파 항법(eLoran) 서비스 영역, 중파 R-Mode 서비스 영역 및 주요 항만 등을 고려하여 충청남도 서산시 대산항 지역으로 선정하였다. 보정국 및 감시국을 포함하는 테스트베드 기지국은 대산항에 설치하여 운영을 시작하였다. 테스트베드 실해역 시험을 통한 성능 검증은 2023년 상반기에 진행될 계획이다.

• Journal of Positioning, Navigation, and Timing
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• v.12 no.3
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• pp.215-228
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• 2023

The State Space Representation (SSR) method provides individual corrections for each Global Navigation Satellite System (GNSS) error components. This method can lead to less bandwidth for transmission and allows selective use of each correction. Precise Point Positioning (PPP) - Real-Time Kinematic (RTK) is one of the carrier-based precise positioning techniques using SSR correction. This technique enables high-precision positioning with a fast convergence time by providing atmospheric correction as well as satellite orbit and clock correction. Currently, the positioning service that supports PPP-RTK technology is the Quazi-Zenith Satellite System Centimeter Level Augmentation System (QZSS CLAS) in Japan. A system that provides correction for each GNSS error component, such as QZSS CLAS, requires monitoring of each error component to provide reliable correction and integrity information to the user. In this study, we conducted an analysis of the performance of residual error bounding for each error component. To assess this performance, we utilized the correction and quality indicators provided by QZSS CLAS. Performance analyses included the range domain, dispersive part, non-dispersive part, and satellite orbit/clock part. The residual root mean square (RMS) of CLAS correction for the range domain approximated 0.0369 m, and the residual RMS for both dispersive and non-dispersive components is around 0.0363 m. It has also been confirmed that the residual errors are properly bounded by the integrity parameters. However, the satellite orbit and clock part have a larger residual of about 0.6508 m, and it was confirmed that this residual was not bounded by the integrity parameters. Users who rely solely on satellite orbit and clock correction, particularly maritime users, thus should exercise caution when utilizing QZSS CLAS.

• Journal of the korean academy of Pediatric Dentistry
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• v.44 no.1
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• pp.72-81
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• 2017

The aim of this study was to evaluate the effectiveness of artificial saliva contamination and decontamination procedures at different stages of a bonding procedure on the microtensile bond strength (MTBS) of two one-step self-etch adhesives and a two-step total-etch adhesive to dentin of primary teeth. Forty-two extracted sound primary molars were randomly divided into three groups depending on three adhesives, Scotchbond Universal Adhesive (SBU), All-Bond Universal (ABU) and Prime & Bond NT (PNT). For each adhesive, the teeth were allocated into seven groups. Except for control group, group 1, the groups were contaminated with artificial saliva at three different stages: the groups 2 and 3 - before adhesive application; the groups 4 and 5 - before adhesive polymerization; the groups 6 and 7 - after adhesive polymerization. Decontaminating procedures were rinsing, air-drying (group 2, 4, 6) and air-drying (group 3, 5, 7). The specimens were restored with composite resin (Filtek, Z350) and microtensile bond strength was measured. The data was analyzed with one-way ANOVA and Tukey HSD test (p < 0.05). In the control group, using PNT resulted in significantly higher bond strength than when ABU and SBU were used (p < 0.001). For three adhesives, the groups 2, 4 and 6 had greater bond strength than the groups 3, 5 and 7. Also, when the artificial saliva was contaminated before adhesive polymerization (group 4, 5), it showed a significantly lower bond strength. Generally the two-step total-etch adhesive generated a higher bond strength than the one-step self-etch adhesive. Artificial saliva contamination before adhesive polymerization led to a drastic decrease in bond strength, and rinsing with water followed by air-drying could not recover the bond strength.

• Journal of Positioning, Navigation, and Timing
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• v.4 no.4
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• pp.187-193
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• 2015

A maritime Differential Global Positioning System (DGPS) reference station broadcasts correction information to users having a DGPS receiver so that the navigation performance can be improved. A maritime DGPS reference station consists of a reference station (RS) that generates and broadcasts correction information, an integrity monitor (IM) that monitors the integrity of correction information, and a control station (CS) that controls them. A maritime DGPS reference station is continuously operated for 24 hours, and thus improvement in the ease of operation is a major element that can improve the performance of the system. In this study, a configuration of a maritime DGPS reference station that can improve the ease of operation and a relevant protocol were proposed, and an example of the implementation of the proposed system was presented.