• Title/Summary/Keyword: PMR

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Paramagnetic Deshielding Effects by Aryl Groups of Triaryl-9-thioxanthenylphosphonium Perchlorate (삼아릴-9-티오크잔테닐포스포니움 과염소산염의 아릴기에 의한 상자기성 벗김 효과)

  • Kwang Hyun Ahn;Kyong Tae Kim
    • Journal of the Korean Chemical Society
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    • v.25 no.3
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    • pp.190-198
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    • 1981
  • In contrast with pmr (only multiplets at ${\delta}6.6$∼7.8 ppm) spectrum of triphenyl-9-thioxanthenylphosphonium perchlorate and tri-o-methoxyphenyl-9-thioxanthenylphosphonium perchlorate, tri-n-butyl-9-thioxanthenylphosphonium perchlorate and tribenzyl-9-thioxanthenylphosphonium perchlorate showed a doublet at ${\delta}5.58$ and 5.70ppm, respectively, assigned to a methine proton. This value is slightly larger than the corresponding values (${\delta}5.05$~5.30) of 9-arylthioxanthenes but clearly differentiated from those of aromatic protons. This result implys that the downfield shift of a methine proton of triaryl-9-thioxanthenylphosphonium perchlorate is not due to inductive effects of an electron deficient phosphorus atom but paramagnetic deshielding effects by three aryl groups on phosphorus.

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Association of Functional Polymorphisms of the XRCC4 Gene with the Risk of Breast Cancer: A Meta-analysis

  • Zhou, Li-Ping;Luan, Hong;Dong, Xi-Hua;Jin, Guo-Jiang;Ma, Dong-Liang;Shang, Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3431-3436
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    • 2012
  • Objective: X-ray cross-complementing group 4 (XRCC4) is a major repair gene for DNA double-strand breaks (DSB) in the non-homologous end-joining (NHEJ) pathway. Several potentially functional polymorphisms of the XRCC4 gene have been implicated in breast cancer risk, but individually published studies showed inconclusive results. The aim of this meta-analysis was to investigate the association between XRCC4 polymorphisms and the risk of breast cancer. Methods: The MEDLINE, EMBASE, Web of science and CBM databases were searched for all relevant articles published up to June 20, 2012. Potential associations were assessed with comparisons of the total mutation rate (TMR), complete mutation rate (CMR) and partial mutation rate (PMR) in cases and controls. Statistical analyses were performed using RevMan 5.1.6 and STATA 12.0 software. Results: Five studies were included with a total of 5,165 breast cancer cases and 4,839 healthy controls. Meta-analysis results showed that mutations of rs2075686 (C>T) and rs6869366 (G>T) in the XRCC4 gene were associated with increased risk of breast cancer, while rs2075685 (G>T) and rs10057194 (A>G) might decrease the risk of breast cancer. However, rs1805377 (A>G), rs1056503 (G>T), rs28360317 (ins>del) and rs3734091 (A>G) polymorphisms of XRCC4 gene did not appear to have an influence on breast cancer susceptibility. Conclusion: Results from the current meta-analysis suggest that the rs2075685 (G>T) and rs6869366 (G>T) polymorphisms of the XRCC4 gene might increase the risk of breast cancer, whereas rs2075685 (G>T) and rs10057194 (A>G) might be protective factors.

Investigation of N2O Emission and Reduction Effect from MSW Incineration Plant (도시고형폐기물 소각시설에서 발생하는 N2O 발생량 조사 및 저감효과에 관한 연구)

  • Song, Hyun-Ok;Ko, Jae-Churl;Choi, Sang-Hyun;Kim, Duk-Hyun
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.12
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    • pp.672-678
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    • 2017
  • In this study, municipal solid waste (MSW) has collected 3 times and physico-chemical analysis has done. Nitrous oxide emissions from MSW incineration plant were measured continuously by EPA Method 18 and it was compared with the emission by calculation using the emission factor. The $N_2O$ emission of MSW incineration plant was more than twice as large as the emission by calculation. It was found that the installation of abatement facilities in MSW incineration plant is effective in achieving the greenhouse reduction targets and it can be ensure economical efficiency through emission trading system.

Interventional Pain Management in Rheumatological Diseases - A Three Years Physiatric Experience in a Tertiary Medical College Hospital in Bangladesh

  • Siddiq, Md. Abu Bakar;Hasan, Suzon Al;Das, Gautam;Khan, Amin Uddin A.
    • The Korean Journal of Pain
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    • v.24 no.4
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    • pp.205-215
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    • 2011
  • Background: Interventional pain management (IPM) is a branch of medical science that deals with management of painful medical conditions using specially equipped X-ray machines and anatomical landmarks. Interventional physiatry is a branch of physical medicine and rehabilitation that treats painful conditions through intervention in peripheral joints, the spine, and soft tissues. Methods: A cross-sectional study was conducted using three years of hospital records (2006 to 2008) from the Physical Medicine and Rehabilitation Department at Chittagong Medical College Hospital in Bangladesh, with a view toward highlighting current interventional pain practice in a tertiary medical college hospital. Result: The maximum amount of intervention was done in degenerative peripheral joint disorders (600, 46.0%), followed by inflammatory joint diseases (300, 23.0%), soft tissue rheumatism (300, 23.0%), and radicular or referred lower back conditions (100, 8.0%). Of the peripheral joints, the knee was the most common site of intervention. Motor stimulation-guided intralesional injection of methylprednisolone into the piriformis muscle was given in 10 cases of piriformis syndrome refractory to both oral medications and therapeutic exercises. Soft tissue rheumatism of unknown etiology was most common in the form of adhesive capsulitis (90, 64.3%), and is discussed separately. Epidural steroid injection was practiced for various causes of lumbar radiculopathy, with the exception of infective discitis. Conclusion: All procedures were performed using anatomical landmarks, as there were no facilities for the C-arm/diagnostic ultrasound required for accurate and safe intervention. A dedicated IPM setup should be a requirement in all PMR departments, to provide better pain management and to reduce the burden on other specialties.

Linear Free Energy Relationship on the Chemical Shift of Imidoyl Proton in N-benzylideneaniline Derivatives by PMR Spectrometry (核磁氣 共鳴分光法에 義한 N-Benzylideneaniline 誘導體중 Imidoyl Proton 의 Chemical Shift 에 미치는 自由에너지 關係)

  • Nack Do Sung;Cheon Kyu Park;Moon kyu Park;Ki Sung Kwon;Kim, Tae Rin
    • Journal of the Korean Chemical Society
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    • v.29 no.3
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    • pp.277-282
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    • 1985
  • The effects of linear free energy relationship (LFER) on the imidoyl proton (H${\alpha}$)-substituent chemical shift (SCS) in case of varying para-substituted C-phenyl group in N-benzylideneaniline derivatives were studied. The H${\alpha}$-SCS values and LFER parameters such as ${\sigma}$,${\sigma}^+$, ${\sigma}_I$,${\sigma}_R, F and R were applied to the Hammett, Okamoto-Brown, and Taft, Swain-Lupton's dual substituents parameter (DSP) equations. The results were: (1) the blending coefficient values, ${\lambda}$ = 2.8∼3.2, it's means that the resonance effect (R) was larger than inductive effect (I) and field effect (F), and (2) the values of percent resonance and percent field effects were %R = 66.6 and %F = 33.4, respectively, yielding the ratio of resonance effect (R) to field effect (F) of 2 : 1.

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A femtosecond Cr:LiSAF laser pumped by semiconductor lasers (반도체 레이저 여기 펨토초 Cr:LiSAF 레이저)

  • 박종대
    • Korean Journal of Optics and Photonics
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    • v.11 no.5
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    • pp.360-364
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    • 2000
  • We demonstrate self-starting passIve mode locking of a Cr:LiSAF laser, using a SCIDlconduclor Saturable Absorber Mirror (SESAM), Two high-power red semiconductor lasers (Coherent S-67-500C-100-H) of wavelength 667 nm and maximum power of 500 mW were used as pump lasers, The cavity has 10 cm radius-ai-curvature folding minors, two SF 10 prisms, a 99% reflectivity output coupler and a SESAM at dIe focus of a 10 cm radIus-at-curvature mirror. We used the laser crystal in BrewsterBrewster shape with 1 5% $Cr^{+3}$ ion concentration and the length of 6 mm, An X-shaped resonator was used to compensate the astigmatism induced by tile crystal. The structure of the SESAM cOllSists of 30 pmr of $AlAs/Al_{0.15}Ga_{0.85}As$ layer, wi1l1 a 10 nm GaAs quantum well situated in the topmost layer Output spectra were centeled at 833 nm, with 4 nm spectral bandwidth and pulse width was measured to be 220 fs, Output power of 3 mW is obtained at a pump power of 800 mW. 00 mW.

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The Fibrinogen to Mean Platelet Volume Ratio Can Predict Overall Survival of Patients with Non-Metastatic Gastric Cancer

  • Song, Shubin;Cong, Xiliang;Li, Fengke;Xue, Yingwei
    • Journal of Gastric Cancer
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    • v.18 no.4
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    • pp.368-378
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    • 2018
  • Purpose: Fibrinogen and platelets have been reported to play important roles in tumorigenesis and cancer progression. The aim of this research was to investigate the combination of functions of fibrinogen, platelets, and mean platelet volume (MPV) in predicting the survival of patients with gastric cancer (GC). Materials and Methods: A retrospective study was conducted with 1,946 patients with GC and 299 patients with benign gastric tumor to analyze their fibrinogen, platelet, and MPV levels, and other clinicopathological characteristics along with their prognoses. Several indicators were evaluated along with fibrinogen, platelets, and MPV and their prognostic abilities were assessed. Univariate and multivariate survival analyses were conducted to determine the independent risk factors for overall survival. Results: Increased levels of fibrinogen, platelets, and MPV were observed with the progress of the GC stages. Elevated fibrinogen, platelets, and the combined indicators, including fibrinogen*MPV (FM), platelet*fibrinogen*MPV (PFM), fibrinogen/MPV (FMR), platelet*fibrinogen (PF), platelet*fibrinogen/MPV (PFMR), platelet*MPV (PM), and platelet/MPV (PMR), foreboded poor prognosis. Meanwhile fibrinogen and FMR can be considered as independent risk factors for overall survival in patients with non-metastatic GC. But these indicators can hardly predict survival of patients in stage IV. Conclusions: Elevated fibrinogen, platelets, and MPV levels were in accordance with advanced stages, and fibrinogen, platelet, and MPV, in combination, can be used to predict survival of patients with non-metastatic GC. FMR was an independent prognostic factor for overall survival of patients with GC.

Effect of Mulching Material on Growth and Yield of Cucumis melo L. cv. Reticulatus (멀칭재료가 멜론 생육 및 수량에 미치는 영향)

  • Kyu Hoi Lee;Min-Jeong Lee;Ju Hyoung Kim;Young Ho Kim
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.67-67
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    • 2020
  • 멜론(Cucumis melo L. cv. Reticulatus)은 다른 과채류에 비해 재배기간이 짧고 수확 시 노동력이 덜 필요로 하는 작물로 고품질 멜론 생산 시 판로 및 가격이 높게 형성되어 농가소득 향상에 적합한 작물이다. 멜론의 국내 시장규모는 1,000억원 정도이며, 일본의 멜론 시장은 4조원으로 40배 정도 큰 시장을 형성하고 있으므로, 수출을 위한 고품질 재배기술 개발이 필요하다. 따라서, 본 연구는 충청북도농업기술원 시험연구포장에서 고온기 근권 환경 최적화를 위한 멀칭 방법을 구명하기 위해 수행하였다. 멜론은 얼스마운틴 PMR 품종을 4월 29일에 120 × 50 cm 로 정식하였으며, 멀칭 처리는 녹색비닐, 검정부직포, 종이멀칭지를 난괴법 3반복으로 각각 피복하였다. 멀칭자재별 생육특성 중 초장은 녹색비닐과 종이멀칭 피복처리에서 각각 148.1 cm, 144.8cm 로 우수하였으며, 엽폭 및 엽장은 유의성 있는 차이가 나타나지 않았다. 생체중은 종이멀칭지로 피복한 처리에서 716.7 g plant-1 로 가장 우수하게 나타났다. 과특성 중 과직경은 녹색비닐과 종이멀칭 피복처리에서 각각 16.1 cm로 우수하였으며, 과중은 종이멀칭지로 피복한 처리에서 2,235 g plant-1 로 가장 우수하게 나타났다. 이처럼 멀칭재료에 따른 생육특성 차이를 확인하였으며, 이러한 적정 멀칭자재 선발을 통해 여름철 고온기 근권 환경 최적화를 통한 멜론 수량 및 품질향상에 기여할 것으로 판단된다.

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Primary Radiation Therapy of Polymorhic Reticulosis (다형성 세망증의 방사선 치료성적)

  • Kim Jae Sung;Yun Hyoung Geun;Ahn Yong Chan;Park Charn Il
    • Radiation Oncology Journal
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    • v.9 no.1
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    • pp.111-116
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    • 1991
  • From 1979 to 1987, 33 patients with polymorphic reticulosis (PMR) limited in the upper airway were treated with primary radiation therapy and the analysis of treatment results was undertaken. Systemic symptoms such as fever, night sweats, and weight ioss were noted in $48\%$. The nasal cavity was most frequently involved $(85\%)$, although involvement of PNS $(33\%)$ and palate $(30\%)$ was not uncommon. The 5 and 10 year actuarial survival rates were $47\%\;and\;40\%$, respectively. The difference in NSD between patients with in-field failure and those without it was significant statistically. Also, field size was significantly smaller in patients with marginal failure than those without it. During the follow-up period, systemic failure was found in S patients (diffuse histiocytic Iymphoma in 4, histiocytic medullary reticulosis in 1). In this study, we can suggest that total radiation dose of at least 4500 cGy with generous treatment volume should be delivered to achieve better local control and that the developement of an effective systemic chemotherapeutic regimen is required to improve the survival after systemic relapse.

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The Development of N2O Emission Factor at Municipal Solid Waste Incinerator (도시고형폐기물 소각시설의 N2O 배출계수 개발)

  • Ko, Jae Churl;Choi, Sang Hyun
    • Clean Technology
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    • v.25 no.1
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    • pp.40-45
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    • 2019
  • In this study, nitrous oxide ($N_2O$) emission concentration was measured 3 times continuously for 24 hours from August 27, 2018 to October 22, 2018 and non-dispersive infrared (NDIR) spectrometer was used to calculate $N_2O$ concentration of exhaust gas from municipal solid waste (MSW) incinerator. As a result of $N_2O$ emission characteristics, it is estimated that $N_2O$ emission concentration is due to the difference of furnace temperature, oxygen concentration rather than the chemical component of waste. The measured $N_2O$ emission concentration of MSW incinerator was obtained in the range of 53.6 ~ 59.5 ppm and the total average concentration was measured 55.6 ppm. Therefore, the amount of $N_2O$ emissions calculated from the $N_2O$ concentration was $98.05kg\;day^{-1}$ on average and the amount of $N_2O$ distribution in the range of $90.41{\sim}108.44kg\;day^{-1}$ was obtained. As a result, the $N_2O$ emission factor of the MSW incinerator was estimated to be $1,066.13g_{N_2O}\;ton_{waste^{-1}}$. The estimated $N_2O$ emission factor of the MSW incinerator was 20 times higher than calculated emission factor used in the Tier 2 method. Consequently, it is considered that the method of calculating the amount of $N_2O$ emission in the MSW incineration facilities using waste type and incineration amount needs to be supplemented to ensure accuracy.