• Title/Summary/Keyword: PMR

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Application of Carbon-13 NMR spectroscopy to the chemistry of natural products

  • Yamasaki, Kazuo
    • Archives of Pharmacal Research
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    • v.3 no.1
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    • pp.57-64
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    • 1980
  • Carbon-13 NMR spectroscopy(abbreviated CMR) is an extremely powerful strategy for the study of natural organic molecules. The information derivable from CMR is often complementary to that obtianed form proton NMR spectroscopy (PMR). Because of low natural abundance of $^{13}C$ nucleus (1.1%) coupled with low inherent sensitivity relative to $^{1}H$ (about 1/64), CMR experiment is approximately 6000 times less sensitive than PMR. Despite of this, now it is possible to measure CMR of small amount of compound by the development of three significant ingenious techniques, i. e. a) computer time-averaging, b) wide-band (or noise modulated) proton decoupling, and c) pulsed Fourier transform (FT) NMR : For general recognition of CMR, its fundamental aspects of CMR are briefly reviewed.

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The pterygomandibular raphe: a comprehensive review

  • Rithvik Vutukuri;Norio Kitagawa;Keiko Fukino;R. Shane Tubbs;Joe Iwanaga
    • Anatomy and Cell Biology
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    • v.57 no.1
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    • pp.7-12
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    • 2024
  • The pterygomandibular raphe (PMR) is a tendinous structure connecting the bucinator and the superior pharyngeal constrictor muscles. With its implications in the spread of oral cancer, the proper treatment of obstructive sleep apnea, and dental procedures, it is important to obtain a thorough understanding of the PMR. We reviewed the existing literature to compile the published information regarding its anatomy, embryology, imaging, variations, functions, pathologies, and clinical relevance of the pterygomandibular raphe.

Radiation Therapy Result of Polymorphic Reticulosis (다형성 세망증(Polymorphic Reticulosis)의 방사선 치료 성적)

  • Chung, Eun-Ji;Kim, Gwi-Eon;Park, Young-Nyun
    • Radiation Oncology Journal
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    • v.11 no.1
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    • pp.83-90
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    • 1993
  • During the period from January, 1975, to June, 1989, one hundred patients with histopathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatmemt results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement ($56{\%}$), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was $24{\%}$. Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were $38.4{\%}$. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following: local failure alone (30/55=$54.6{\%}$), systemic failure alone (9/55=$16.4{\%}$), both local and systemic failure (16/55=$29.0{\%}$). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.

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Acrylic Polymer Composition Suitable for Ion Delivery and Selective Detection of Proton, and Hydroxyl and Cu(II) Ions (이온 이동에 적합한 아크릴고분자 박막의 조성과 수소이온, 수산화이온, 구리이온의 선택적 검출)

  • Lee, Dahye;Woo, Heejung;Do, Jung Yun
    • Polymer(Korea)
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    • v.38 no.6
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    • pp.801-808
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    • 2014
  • Ion diffusion and chemical binding to acrylic polymer were investigated in a solid film. The composition of acrylic monomers containing amino group and carboxylic acid was adjusted for rapid ion migration in the film. p-Methylred (PMR) and phenolphthalein derivatives were optically sensitive to the concentration of proton and hydroxyl anion, respectively and verified the ion migration through the film layers. A rapid proton migration was observed in the film of a high amino content. On the other hand, $OH^-$ migration occurred rapidly in a high content of carboxylic acid group. The proton migration occurred through the internal layer as well as surface layer of a film and was reversible during 50 repetition examination. Copper(II) ion migration was examined with a Rhodamine-containing polymer film. The light absorption and emission spectra of a Rhodamine-Cu complex showed the key contribution of carboxylic acid group to the Cu(II) migration in a film.

Performance comparison between two computer-aided detection colonoscopy models by trainees using different false positive thresholds: a cross-sectional study in Thailand

  • Kasenee Tiankanon;Julalak Karuehardsuwan;Satimai Aniwan;Parit Mekaroonkamol;Panukorn Sunthornwechapong;Huttakan Navadurong;Kittithat Tantitanawat;Krittaya Mekritthikrai;Salin Samutrangsi;Peerapon Vateekul;Rungsun Rerknimitr
    • Clinical Endoscopy
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    • v.57 no.2
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    • pp.217-225
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    • 2024
  • Background/Aims: This study aims to compare polyp detection performance of "Deep-GI," a newly developed artificial intelligence (AI) model, to a previously validated AI model computer-aided polyp detection (CADe) using various false positive (FP) thresholds and determining the best threshold for each model. Methods: Colonoscopy videos were collected prospectively and reviewed by three expert endoscopists (gold standard), trainees, CADe (CAD EYE; Fujifilm Corp.), and Deep-GI. Polyp detection sensitivity (PDS), polyp miss rates (PMR), and false-positive alarm rates (FPR) were compared among the three groups using different FP thresholds for the duration of bounding boxes appearing on the screen. Results: In total, 170 colonoscopy videos were used in this study. Deep-GI showed the highest PDS (99.4% vs. 85.4% vs. 66.7%, p<0.01) and the lowest PMR (0.6% vs. 14.6% vs. 33.3%, p<0.01) when compared to CADe and trainees, respectively. Compared to CADe, Deep-GI demonstrated lower FPR at FP thresholds of ≥0.5 (12.1 vs. 22.4) and ≥1 second (4.4 vs. 6.8) (both p<0.05). However, when the threshold was raised to ≥1.5 seconds, the FPR became comparable (2 vs. 2.4, p=0.3), while the PMR increased from 2% to 10%. Conclusions: Compared to CADe, Deep-GI demonstrated a higher PDS with significantly lower FPR at ≥0.5- and ≥1-second thresholds. At the ≥1.5-second threshold, both systems showed comparable FPR with increased PMR.

Interference Analysis for Deployment of the Efficient Village Broadcasting Radio System (마을방송 시스템의 효율적 구축을 위한 간섭분석)

  • Kang, Young-Heung
    • Journal of Advanced Navigation Technology
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    • v.21 no.4
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    • pp.359-364
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    • 2017
  • Since the existing analog village broadcasting system has some technical problems in applying and degradations in performance due to its old equipments, it had been required recently to be changed to a wireless digital system and to develop the standardization. However, it is important to analyze the interference between villages in deploying the efficient digital wireless village broadcasting system. In this paper, simulations for co-channel and adjacent channel interference have been carried out considering digital private mobile radio(dPMR) and digital mobile radio(DMR) systems as a representative mobile radio. These results for frequency reuse and channel separation drawn from the separation distance between villages in co-channel interference and the frequency offset in adjacent interference can be helpful to establish a standard and the testing service in the near future.

A pentacyclic triterpenoid possessing analgesic and anti-inflammatory activities from the fruits of Dregea volubilis

  • Biswas, M.;Biswas, K.;Ghosh, A.K.;Haldar, P.K.
    • Advances in Traditional Medicine
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    • v.9 no.4
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    • pp.315-319
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    • 2009
  • In present study evaluate the analgesic and anti-inflammatory activity of the compound obtained from the petroleum ether (40 - 60$^{\circ}C$) extract of the fruits from Dregea volubilis in Swiss albino mice and in Wister albino rats respectively. Dried and crushed fruits of Dregea volubilis were extracted by petroleum ether (40 - 60$^{\circ}C$), the proper solvent system was developed by TLC and subjected to column chromatography for obtaining the pure compound/s. IR, MASS, NMR (PMR, C13 NMR and DEPT) spectroscopic analysis were done to elucidate the structure of the compound/s. The petroleum ether (40 - 60$^{\circ}C$) extract of the fruits of Dregea volubilis led to isolation of a pentacyclic triterpenoid designated as taraxerone and characterized as D- friedoolean- 14- en, 3 one. Taraxerone had been screened for analgesic activity in Swiss albino mice and anti-inflammatory activity in Wister albino rats at the dose of 5 mg/kg body weight orally and exhibit significant analgesic and anti-inflammatory properties.

Study for Improvement of the Doctor's Satisfaction and Completeness of the Medical Record in the EMR System (전자의무기록(EMR) 시스템하에서 의사의 만족도와 의무기록정보의 기재 충실도 향상 방안)

  • Park, Un-Je
    • Korea Journal of Hospital Management
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    • v.16 no.2
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    • pp.19-30
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    • 2011
  • This study aims to present ways to enhance the stabilization of electronic medical records, ensure the commitment to filling in information of the medical record and improve the overall quality Electronic Medical Record(EMR) information. For that purpose, the present state of the incomplete record rate and the doctor's satisfaction in Electronic Medical Record(EMR) have been surveyed by comparing and analyzing Paper-based Medical Record(PMR) and Electronic Medical Record(EMR). The survey was conducted on 31 doctors in charge of EMR system and each PMR and EMR inpatients were collected for a period of 5 months and analyzed. The results showed that the doctor's satisfaction level was higher for EMR, and the rate of incomplete record appeared to be lower in EMR in departments of both internal and external medicine. In this context, it can be said that the higher efficiency of EMR helped accomplish the increase in commitment to completing medical record information and improve the quality of the data.

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