• 한국전산구조공학회논문집
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• 제26권4호
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• pp.223-231
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• 2013

본 논문에서는 물성이 균일하지 않은 반무한 고체영역의 탄성파속도 분포를 재구성하기 위한 시간영역 Gauss-Newton 전체파형 역해석 기법을 소개한다. 반무한 영역을 유한 계산영역으로 치환하기 위하여 유한영역의 경계에 수치적 파동흡수 경계조건인 perfectly-matched-layers(PMLs)를 도입하였다. 이 역해석 문제는 PML을 경계로 하는 영역에서의 탄성파동방정식을 구속조건으로 하는 최적화 문제로 성립되며, 표면에서 측정된 변위응답과 혼합유한요소법에 의해 계산된 응답간의 차이를 최소화함으로써 미지의 탄성파속도 분포를 결정한다. 이 과정에서 Gauss-Newton-Krylov 최적화 알고리즘과 정규화기법을 사용하여 탄성파속도의 분포를 반복적으로 업데이트하였다. 1차원 수치예제들을 통해 Gauss-Newton 역해석으로 부터 재구성된 탄성파속도의 분포가 목표값에 충분히 근사함을 보였으며, Fletcher Reeves 최적화 알고리즘을 사용한 기존의 역해석 결과에 비해 수렴율이 현저히 개선되고 계산 소요시간이 단축됨을 확인할 수 있었다.

• 대한치과교정학회지
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• 제45권4호
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• pp.190-197
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• 2015

Objective: The aim of the study was to analyze the prevalence and distribution of ectopic eruption of the permanent maxillary first molar (EEM) in individuals scheduled for orthodontic treatment and to investigate the association of EEM with dental characteristics, maxillary skeletal features, crowding, and other dental anomalies. Methods: A total of 1,317 individuals were included and randomly divided into two groups. The first 265 subjects were included as controls, while the remaining 1,052 subjects included the sample from which the final experimental EEM group was derived. The mesiodistal (M-D) crown width of the deciduous maxillary second molar and permanent maxillary first molar, maxillary arch length (A-PML), maxillomandibular transverse skeletal relationships (anterior and posterior transverse interarch discrepancies, ATID and PTID), maxillary and mandibular tooth crowding, and the presence of dental anomalies were recorded for each subject, and the statistical significance of differences in these parameters between the EEM and control groups was determined using independent sample t -tests. Chi-square tests were used to compare the prevalence of other dental anomalies between the two groups. Results: The prevalence of maxillary EEM was 2.5%. The M-D crown widths, ATID and PTID, and tooth crowding were significantly greater, while A-PML was significantly smaller, in the EEM group than in the control group. Only two subjects showed an association between EEM and maxillary lateral incisor anomalies, which included agenesis in one and microdontia in the other. Conclusions: EEM may be a risk factor for maxillary arch constriction and severe tooth crowding.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6347-6350
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• 2013

Post-transplant lymphoproliferative disorder (PTLD) is a common complication of therapeutic immunosuppression after organ transplantation. Gene expression profile facilitates the identification of biological difference between Epstein-Barr virus (EBV) positive and negative PTLDs. Previous studies mainly implemented variance/regression analysis without considering unaccounted array specific factors. The aim of this study is to investigate the gene expression difference between EBV positive and negative PTLDs through partial least squares (PLS) based analysis. With a microarray data set from the Gene Expression Omnibus database, we performed PLS based analysis. We acquired 1188 differentially expressed genes. Pathway and Gene Ontology enrichment analysis identified significantly over-representation of dysregulated genes in immune response and cancer related biological processes. Network analysis identified three hub genes with degrees higher than 15, including CREBBP, ATXN1, and PML. Proteins encoded by CREBBP and PML have been reported to be interact with EBV before. Our findings shed light on expression distinction of EBV positive and negative PTLDs with the hope to offer theoretical support for future therapeutic study.

• 한국환경성돌연변이발암원학회지
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• 제22권1호
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• pp.39-46
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• 2002

Obesity is a complex metabolic disorder with a strong genetic component. There are many candidate genes for obesity and its related phenotypes. We studied genetic variations between Korean obese and lean groups. Polymorphisms investigated were the Msp I polymorphism of the $\alpha$$_{2A}$-adrenergic receptor ($\alpha$$_{2A}$-AR) gene, the Mnl I polymorphism of the $\alpha$$_2$-adrenergic receptor ($\alpha$$_2$-AR) gene, the BstO I polymorphism of the $\beta$$_3$-adrenergic receptor ($\beta$$_3$-AR) gene, the Pml I polymorphism of the lamin A/C (LMNA) gene, the Hga I polymorphism of the clearance receptor (NPRC) gene, the Msp I polymorphism of the leptin gene, BclI polymorphism of the uncoupling protein 1 (UCPI) gene and the Hha I polymorphism of the fatty acid binding protein 2 (FABP2) gene. Among these genetic markers, Pml I polymorphism at the LMNA gene and Bcl I polymorphism at the UCP1 gene were significantly associated with obesity. However, further studies are required whether thease findings are reproduced in large population, although two polymorphisms might be useful as genetic markers in the ethiology of obesity in Korean population.ion.

• 한국전자파학회논문지
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• 제9권5호
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• pp.567-577
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• 1998

유한차분 시간영역 방법을 이용하여 연속 및 불연속 마이크로스트립올 해석할 때 홉수 경계조건은 Berenger의 완전 접합충(Perfectly Matched Layer:PML)올 3차원으로 적용하고, 전원의 인가는 기존의 마이크로스트립 전면(front face)에 인가하는 방법 대신 내부전원(Inner Source Technique:IST)을 이용하였다. 이 방법을 이용하면 de성분의 왜곡이 개선되고, 에베네센트(evanescent) 및 복사 전자계가 존재하는 측면과 윗면의 계산 영역올 줄이더라도 해석된 특성은 신뢰할 수 있는 결과를 얻올 수 있었다. 또한 내부전원의 위치를 조정함으로서 불완전한 경계조건에 의해서 발생되는 반사파의 영향올 효과적으로 제거할 수 있었다. 본 연구에서는 이러한 방법을 이용하여 마이크로스트립의 분산특성 및 특성임피던스를 계산하였다. 그리고 종단개방 마이크로스트립의 산란계수의 크기와 위상올 구하고 그 동가회로를 계산하였다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2000년도 봄 학술발표회논문집
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• pp.177-186
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• 2000

An improved multi-level（IML) optimization algorithm using automatic differentiation (AD) for multi-objective optimum design of framed structures is proposed in this paper. In order to optimize the steel frames under seismic load, two main objective functions need to be considered for minimizing the structural weight and maximizing the strain energy. For the efficiency of the proposed algorithm, multi-level optimization techniques using decomposition method that separately utilizes both system-level and element-level optimizations and an artificial constraint deletion technique are incorporated in the algorithm. And also to save the numerical efforts, an efficient reanalysis technique through approximated structural responses such as moments, frequencies, and strain energy with respect to intermediate variables is proposed in the paper. Sensitivity analysis of dynamic structural response is executed by AD that is a powerful technique for computing complex or implicit derivatives accurately and efficiently with minimal human effort. The efficiency and robustness of the IML algorithm, compared with a plain multi-level (PML) algorithm, is successfully demonstrated in the numerical examples.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2004년도 하계종합학술대회 논문집(1)
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• pp.131-134
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• 2004

This paper has been studied a ADI-FDTD(Alternating Direction Implicit Finite Difference Time Domain ) algorithm using an alternating Direction time-stepping scheme for GPR( Ground-Penetrating Radar ) system simulation. We did the numerical formulations for three-dimensional ADI-FDTD algorithm and PML(Perfect Matched Layer), and made an simple experiment on a arbitrary cube with programed algorithms. And then we compared its computed results with those of conventional FDTD.

• 한국수학교육학회지시리즈D:수학교육연구
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• 제14권3호
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• pp.233-247
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• 2010

The article deals with the perceptions of Mathematics as a language of pre-service teachers of Mathematics in a College of Education in Israel. The formal language of studying in the College of Education is Hebrew. The goals of the study were to examine the perceptions of pre-service teachers on the following issues: the language components involved in learning Mathematics, the basic cognitive skills required for learning Mathematics, and the perception of Mathematics as a language (PML). Findings indicated that due to new attitudes in mathematical training, pre-service teachers of Mathematics perceived Mathematics as a language regarding all language components.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2003년도 봄 학술발표회 논문집
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• pp.249-254
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• 2003

The thermal coefficient of concrete is measured using dilatometer (AASHTO TP60) and strain gage. Testing parameters such as six different coarse aggregate types, cycles of warming and cooling, specimen shape and measurement types were investigated to evaluate the influencing factors for thermal coefficient of concrete. According to experimental results, the thermal coefficient of concrete made with crushed aggregate showed 9.2 -10.$\mu\varepsilon/^{\circ}C$, , however recycled coarse aggregate classified type II showed a little increasing in comparison with crushed aggregate. The thermal coefficient of concrete made with recycled aggregate was reduced 0.2-0.4$\mu\varepsilon/^{\circ}C$, under temperature cycles. However, specimen shapes were revealed as mainly affecting factors on the thermal coefficient of concrete. Finally the thermal coefficient value determined by the dilatometer device was shown to be similar to the value from PML 60.

• 한국광학회:학술대회논문집
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• 한국광학회 2001년도 제12회 정기총회 및 01년도 동계학술발표회
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• pp.236-237
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• 2001

최근 빠른 정보산업의 발달로 대용량의 정보를 초고속으로 전달해야 할 필요성으로 인해 광전송 시스템의 개발이 활발히 진행되고 있다. 특히 광통신 시스템이나 주변의 계측장비들과의 결합이 쉽다는 잇점 때문에 모드록킹된 광섬유 레이저는 이 분야의 광원으로서 매우 중요하게 쓰이고 있으며, 연구가 많이 진행되고 있다. 본 실험에 사용된 광섬유 레이저는 파장 1.55 $mu extrm{m}$대역에서 이득을 얻을 수 있는 어븀(Er$^{3+}$ )이 첨가된 광섬유를 사용하여 4.5 MHz의 빠른 반복률로 모드록킹 되도록 제작된 (Newgrid, (FFL-1550-PML-0) 것이며 펄스 폭은 320 fs, 중심파장은 1.566 $\mu\textrm{m}$, 펄스의 첨두 출력은 6.3 kW이다. (중략)