• Title/Summary/Keyword: PM3 method

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Recovery Trajectory in Tachycardia Induced Heart Failure Model (빈맥을 이용한 심부전 모델에서 회복궤도)

  • 오중환;박승일;원준호;김은기;이종국
    • Journal of Chest Surgery
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    • v.32 no.5
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    • pp.422-427
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    • 1999
  • Background: Tachycardia induced heart failure model would be the model of choice for the dilated cardiomyopathy. This more closely resembles the clinical syndrome and does not require major surgical trauma, myocardial ischemia and pharmacological or toxic depression of cardiac function. When heart failure is progressive, application of new surgical procedures to the faling heart is highly risky. It has been shown that recovery trajectory from heart failure is a new method in decreasing animal mortality. The purpose is to establish the control datas for recovery trajectory in the canine heart failure model. Material and Method: 21 mongrel dogs were studied at 4 stages(baseline, at the heart failure, 4 and 8 weeks after recovery). Heart failure was induced during 4 weeks of continuous rapid pacing using a pacemaker. Eight weeks of trajectory of recovery period was allowed. Indices of left ventricular function and dimension were measured every 2 weeks and the hemodynamics were measured by use of Swan-Ganz catheterization and thermodilution method every 4 weeks. Values were expressed as mean${\pm}$standard deviation. Result: 4(20%) dogs died due to heart failure. Left ventricular end-diastolic volume at the 4 stages were 40.8${\pm}$7.4, 82.1${\pm}$21.1, 59.9${\pm}$7.7 and 46.5${\pm}$6.5ml. Left ventricular end-systolic volume showed the same trend. Ejection fractions were 50.6${\pm}$4.1, 17.5${\pm}$5.8, 36.3${\pm}$7.3, and 41.5${\pm}$2.4%. Blood pressure and heart rate showed no significant changes. Pressures of central vein, right ventricle, pulmonary artery, and pulmonary capillary wedge showed significant increase during the heart failure period, normalizing at the end of recovery period. Stroke volumes were 21.5${\pm}$8.2, 12.3${\pm}$3.5, 17.9${\pm}$4.6, and 15.5${\pm}$3.4ml. Blood norepinephrine level was 133.3${\pm}$60.0pg/dL at the baseline and 479.4${\pm}$327.3pg/dL at the heart failure stage(p=0.008). Conclusion: Development of tachycardia induced heart failure model is of high priority due to ready availability and reasonable amenability to measurements. Recovery trajectory after cessation of tachycardia showed reduction of cardiac dilatation and heart function. Application of new surgical procedures during the recovery period could decrease animal mortality.

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Characterization of Airborne Bioaerosol Concentration in Public Facilities (다중이용시설내 공기중 바이오에어로졸 농도분포 특성에 관한 연구)

  • Lee, Cheol Min;Kim, Yun Sin;Lee, Tae Hyeong;Park, Won Seok;Hong, Seung Cheol
    • Journal of Environmental Science International
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    • v.13 no.3
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    • pp.215-222
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    • 2004
  • This study was conducted to evaluate the characterization of airborne bioaerosol in public facilities in Seoul. A total of 17 public facilities were investigated from December, 2002 to February, 2003. As results of the survey, the mean concentrations of bacteria and fungi in indoor air of public facilities were $378.08\pm296.33$ CFU/㎥ by RCS and $106.38\pm171.63$ CFU/㎥ and $347.46\pm335.32$ CFU/㎥ and $95.23\pm62.61$ CFU/㎥, by Six-stage cascade air sampler respectively. The mean concentrations of bacteria in indoor air (by ventilation method) were $517.14\pm343.93$ CFU/㎥ of natural ventilation and $215,83\pm100.71$ CFU/㎥ of mechanical ventilation. The mean concentrations of fungi in indoor air (by ventilation method) were $83.14\pm79.16$ CFU/㎥ of natural ventilation and $133.50\pm248.07$ CFU/㎥ of mechanical ventilation. The mean concentrations of bacteria in indoor air were 449.44 CFU/㎥ for the ground and $217.50\pm103.68$ CFU/㎥ for the underground. The mean concentrations of fungi in indoor air were $63.89\pm77.66$ CFU/㎥ for the ground and $202.00\pm290.08$ CFU/㎥ for the underground.

Exposure Assessment of $PM_{2.5}$ in Manufacturing Industry Office Buildings (사업장 내 사무실의 $PM_{2.5}$ 노출 평가)

  • Nam, Mi Ran;Jung, Jong-Hyon;Phee, Young Gyu
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.23 no.4
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    • pp.356-366
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    • 2013
  • Objectives: This study was conducted in order to evaluate $PM_{2.5}$ concentrations at 20 offices connected to the manufacturing industry from the beginning of September to the end of November 2012. Methods: A total of 20 samples were collected from 20 office buildings. Each $PM_{2.5}$ sample was collected by a 37 mm PTFE filter attached to a Personal Environment Monitor. Results: The geometric mean concentrations of $PM_{2.5}$ in the offices was $23.47{\mu}g/m^3$, and the mean $PM_{2.5}$ concentrations measured in smoking offices were much higher than those of measured in non-smoking offices($24.83{\mu}g/m^3$ and $21.55{\mu}g/m^3$, respectively). $PM_{2.5}$ was revealed to be higher in small offices($39.52{\mu}g/m^3$) than in medium or large offices($22.69{\mu}g/m^3$ and $11.04{\mu}g/m^3$, respectively). The mean $PM_{2.5}$ concentration of offices located on the 1st floor was higher than that of those on the 2nd floor, and those of offices located in the workplace were higher than those out of the workplace. The multiple regression model showed that concentration of $PM_{2.5}$ was positively associated with the method of ventilation. Conclusions: Smoking, ventilation method, location, and inflow of outdoor particulate matter are the most important factors for office $PM_{2.5}$ concentrations.

Functional studies of granulocytes in ruminants 1. Rapid separation of polymorphonuclear leucocytes from circulating blood in bovine (반추동물에서 과립구의 기능에 대한 연구 1. 소의 순환혈액에서 다형핵백혈구의 신속한 분리)

  • 박일규;윤창용;이정원;송희종
    • Korean Journal of Veterinary Service
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    • v.22 no.4
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    • pp.377-383
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    • 1999
  • Polymorphonuclear (PMN) leucocytes are fundamental importance to the body's defense mechanism and play a major role in the local and systemic reactions to infectious disease. Investigation of the physiological and pathological role of the various leucocyte subtypes in host defence mechanisms is dependent upon the isolation of adequate numbers of viable, pure leucocyte fractions. This report describes the separate frequency of PMN leucocytes both from buffy coat layer and from packed RBC layer when bovine peripheral blood was treated with various anti-coagulants such as acid-citrate-dextrose(ACD), ethyldiaminetetraacetic acid(EDTA), sodium citrate and heparin. The separate frequencies of PMN leucocytes from buffy coat layer was 60.4$\pm$9.6%(heparin), 56.8$\pm$11.8%(sodium citrate), 30.6$\pm$14.1%(ACD) and 6.2$\pm$3.7%(EDTA), in order. Those from packed RBC layer monitored with EDTA, ACD, sodium citrate and heparin was 85.0$\pm$4.7%, 84.3$\pm$5.5%, 83.8$\pm$6.5% and 76.3$\pm$7.7%, respectively. The Ficoll-hypaque(FH) density gradient method was used to remove a small part of lymphocytes and/or monocytes from leucocytes in packed RBC layer. With the result that it increased separate frequency of PMN leucocytes from EDTA(89.9$\pm$2.4%), ACD(89.5$\pm$3.6%), and sodium citrate(83.6$\pm$10.3%) than heparin(68.4$\pm$13.9%). These results indicate that the use of EDTA and ACD as anticoagulant Is suitable for the separation of PMN leucocytes from bovine peripheral blood, and that the FH density gradient method is able to increase the separate frequency of PMN leucocytes from packed RBC layer.

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Dustfalls and Various Ion Concentrations in Their Filtrates in an Urban and in a Rural Districts (도시 및 농촌 일부지역의 강하분진과 여과액중의 이온농도)

  • Hong, Yeon-Pyo
    • Journal of Preventive Medicine and Public Health
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    • v.18 no.1
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    • pp.59-71
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    • 1985
  • During a period from February 1st to November 30th in 1983, measurements were made twice a month on dustfalls and concentrations of various cations ana anions in their filtrates in an urban (Heuksuk-dong, Seoul) and in a rural (Ansung) districts. Standard British Deposit Gauge method was applied for collection of dustfalls and ion chromatographic method using Ion Chromatograph 10 (Dionex, U.S.A.) for determination of cation and anion concentrations. The results obtained were as follows: 1. Annual mean values of dustfalls were $8.30{\pm}5.09tons/km^2/month$ in an urban and $6.20{\pm}0.82tons/km^2/month$ in a rural districts. And annual mean values of pH of filtrates of the collected samples were $5.3{\pm}0.76$ in an urban and $6.0{\pm}0.82$ in a rural districts. 2. Annual mean concentrations of common cations and anions in their filtrates were as follows: urban rural (unit: ppm) $$Na^{+}\;1.7{\pm}1.30\;1.9{\pm}1.86$$ $$NH^{+}_{4}\;2.4{\pm}1.60\;1.3{\pm}1.59$$ $$K^{+}\;0.7{\pm}0.47\;1.5{\pm}3.79$$ $$Ca^{++}\;5.3{\pm}0.95\;3.4{\pm}2.58$$ $$Mg^{++}\;0.7{\pm}0.89\;0.5{\pm}0.83$$ $$Cl^{-}\;2.0{\pm}1.31\;4.0{\pm}2.35$$ $$NO^{-}_{3}\;4.0{\pm}2.35\;2.7{\pm}1.31$$ $$So^{--}_{4}\;16.9{\pm}17.40\;6.8{\pm}8.00$$ Some of anions such as $Br^{-},\;{PO_4}^{-3}\;and\;{NO_2}^{-}$ were scarecely detected and $F^{-}$ was measured at very low concentrations ranging from 0.1 to 0.5 ppm in Feb., Oct. and Nov. in an urban and in Feb. in a rural districts. 3. By two-way analysis of variance with 4 replications for dustfalls, pH and concentrations of various ion by district and month of a year, statistically significant differences were noted in dustfalls (p<0.01), pH (p<0.01) and concentrations of various ion (p<0.01) by month of a year, and in dustfalls (p<0.05) and concentrations of various ion such as ${NH_4}^{+},\;Ca^{++},\;{NO_{3}}^{-}\;and\;{SO_4}^{--}$ (p<0.01) by district. 4. There were statistically significant differences pH in Spring (Feb., Mar and Apr.) (p<0.01) and in ${SO_4}^{--}$ in Autumn (Aug., Sept., Oct. and Nov.) (p<0.05) between the two districts.

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Environmental Working Status of Mercury using Industries in Korea (수은 취급사업장 작업환경 실태에 관한 조사연구)

  • Chung, Mu Soo;Hwang, Kyu Yoon;Ahn, Kyu Dong;Lee, Byung Kook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.1 no.2
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    • pp.128-135
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    • 1991
  • To obtain the basic information of environmental working status in mercury industries in Korea, 26 mercury industries were investigated with mercury concentration in air and various factors affecting on workplace environment. The results were as follows : 1. The mean air concentration of mercury was $0.046{\pm}0.035mg/m^3$ in 26 mercury industries. 2. The highest mean air concentration of mercury among 26 mercury industries classified by type of product was found in sodium hydroxide manufacturing industries ($0.054{\pm}0.020mg/m^3$) and the lowest mean was found in mercury battery manufacturing industries ($0.003{\pm}0.002mg/m^3$). 3. While the highest' mean air concentration of mercury was found in manual method ($0.061{\pm}0.041mg/m^3$) among the types of operation method, lowest one was found in automatic method ($0.035{\pm}0.025mg/m^3$). 4. While the mean air concentration of mercury was $0.023{\pm}0.018mg/m^3$ in good clean status of workshop, the mean air concentration of mercury in bad clean status was $0.06{\pm}0.033mg/m^3$. Among various factors affecting on th e air concentration of mercury, clean Iiness of workshop showed statistically significant difference with air concentration of mercury, and automation of workshop and local exhaust ventitlation also played important role in control the air concentration of mercury in the working environment.

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Persulfate Wet Oxidation Method for the Determination of Total Phosphorus in Atmospheric Aerosols and Its Application for a Year-round Observation in Beijing

  • Okuda, Tomoaki;Gunji, Yuma;He, Kebin;Ma, Yongliang
    • Asian Journal of Atmospheric Environment
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    • v.7 no.3
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    • pp.169-175
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    • 2013
  • Measurement of the phosphorus concentration in aerosols in Beijing, which was a representative East Asian mega-city, was carried out. The optimum procedure for analyzing phosphorus in aerosols was found in this study. Recovery of phosphorus in environmental samples through the improved method was almost 100%. The concentration of phosphorus in TSP was $145{\pm}47\;ng/m^3$, with a seasonal variation showing high concentrations in winter and low concentrations in summer. The concentrations of phosphorus in $PM_{2.5}$ accounted for $35{\pm}6%$ of those in TSP, with no seasonal variations. The major source of phosphorus in aerosols in Beijing was soil dust, and additional sources of phosphorus in fine particles could be coal combustion and biomass burning.

Comparison of Attenuation Correction Methods for Brain SPECT Ima (Brain SPECT 영상의 Attenuation Correction 방법들에 대한 비교)

  • Jo, Jin U;Kim, Chang Ho;Na, Soo Kyung;Lee, Gui Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.120-125
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    • 2012
  • Purpose : The purpose of this study was to compare count between Chang's method and CT-based attenuation correction (AC-CT) among the attenuation correction (AC) methods for non-attenuation correction (AC-non) images of Brain SPECT (Single Photon Emission Computed Tomography). Materials and Methods : We injected $^{99m}Tc$ 37Mbq in a Hoffman 3D phantom filled with distilled water in the phantom study, and injected intravenously $^{99m}Tc$-HMPAO 740Mbq in a normal volunteer in the patient study, and then obtained Brain SPECT images with Symbia T6 of Siemens and conducted quantitative brain analysis. Transverse images to which each method was applied were rebuilt at the same position, and 6 regions of interest (ROI) were drawn on each of Slice No. 10, 20 and 30 and then the counts of AC-non, AC-CT and Chang's method were compared. Results : The mean counts of AC-non, AC-CT and Chang's method were $4606.8{\pm}511.3$, $16794.6{\pm}2429.4$, and $8752.6{\pm}896.5$, respectively, in the phantom study and $5460.8{\pm}519.6$, $15320{\pm}1171.6$ and $12795{\pm}1422.1$, respectively, in the patient study. In the phantom study, the ratio of AC-CT to AC-non was 3.70 and the ratio of Chang's method to AC-non was 1.92, and in the patient study, they were 2.85 and 2.38, respectively. Conclusion : From this study, we found that AC-CT makes higher AC than Chang's method. In addition, when Chang's method was used, AC in the patient study was higher than that in the phantom study. These results need to be considered also in other examinations.

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A comparison of in-patients' satisfaction in hospital foodservice method (급식관리방법에 따른 환자 만족도 비교연구)

  • Kim, Jeong-Hui;Han, Min-Yeon;Kim, Ji-Hyeon;Choe, Jeong-Im;Ha, Seung-Hui
    • Journal of the Korean Dietetic Association
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    • v.2 no.1
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    • pp.10-19
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    • 1996
  • The purpose of this study were to improve in foodservice system, and to evaluate the satisfaction of patient meal. Two General Hospitals (A & B) in Ewha Womans University college of Medicine were selected for this study. The survey questionnaire consisted of general backgrounds and foodservice evaluation. We chosed factors which may influence meal satisfaction such as meal time, amount, optimal temperature, taste, quality, sanitary condition, and employee' s kindness. One-way ANOVA and Pearson' s correlation were used as statistical methods. The results can be summarized as follows 1. In meal time, for the A&B hospitals were 3.46$\pm$0.93 3.63$\pm$0.76 respectively. 2. In cold foods for the A&B hospitals were 3.23$\pm$0.89 3.52$\pm$0.78 respectively while in hot foods 3.29$\pm$1.02 3.27$\pm$0.90 respectively for A&B hospitals. 3. In taste for the A&B hospitals were 2.81$\pm$0.96 3.01$\pm$0.95 respectively. 4. In quality were 2.93$\pm$0.92 3.25$\pm$0.91 respectivly. 5. In amount were 3.38$\pm$0.95 3.36$\pm$0.98 respectively. 6. In sanitary condition for the A&B hospitals were 3.55$\pm$0.88 3.12$\pm$0.97 respectively. 7. In kindness were 3.11$\pm$0.87 3.32$\pm$0.76 respectively. 8. Quality, taste, meal time, kindness, sanitary condition, temperature, amount, age, duration, and room grade were significantly correlated to the satisfaction of patient meal in order.

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Satisfaction with Evaluation Method for Fundamental Nursing Practical Skill Education Through Cell Phone Animation Self-Monitoring and Feedback - Focus on Foley Catheterization - (휴대폰 동영상 자기관찰 및 피드백을 통한 기본간호학 실기 교육평가방법에 관한 만족도 - 정체도뇨관 삽입을 중심으로 -)

  • Kim, Yeong-Hie
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.15 no.2
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    • pp.134-142
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    • 2008
  • Purpose: This study was done to identify satisfaction with the method of evaluating practical skills in fundamental nursing through cellular phone animation self-monitoring and feedback. Method: The participants were 163 first-year student nurses. Data were collected from October 1 to 5 2007 using a structured questionnaire. Results: The average score for satisfaction was 3.65(${\pm}.69$) and the highest score was for the item, "I was pleased to have the opportunity of relearning by looking back at my behaviors through self monitoring" with 4.05(${\pm}.89$). The average score for dissatisfaction was 3.23(${\pm}.90$) and the highest score was "I memorized only orders according to the checklist" with 3.65(${\pm}.97$). The practical tests method showed a significant difference according to motivation for application to college of nursing (F=3.11, p=.047). There was a significant positive correlation between practical education satisfaction and test method (r=.363, p=.000). Conclusion: These findings show that there is a need to develop strategies to improve practical test methods for student nurses.

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