• 동의생리병리학회지
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• 제17권1호
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• pp.123-129
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• 2003

Experimental studies were done to research the dinical effects of Juglandis Semen aqua-acupuncture and acupuncture(BL 13) on the anti-allergic response. anaphylaxis provoked by the compound 48/80, delayed type hypersensitivity response to picryl chloride and SASC and inflammation response to egg albumin. The following results have been obtained: Juglandis Semen aqua-acupuncture and acupuncture(BL13) group were increased the survival rate in compound48/80 induced systemic anaphylactic reaction. Picryl chloride induced contact dermatitis and delayed type hypersensitivity in SRBC challenged mouse were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture (BL13) group. Inflammation response - WBC, CRP and Nitric Oxide in egg albumin induced allergic rat were significantly decreased in Juglandis Semen aqua-acupuncture and acupuncture(BL13) group. According to the above results, Semen aqua-acupuncture and acupuncture(BL13) both depress the allergy reaction.

• 대한인간공학회지
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• 제21권2호
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• pp.59-70
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• 2002

This paper is about the evaluation of stress response and recovery using biosignals and fuzzy theory. We caused mental stress by means of a coin-stacking task. During the experiment, 4 kinds of biosignals, including frontalis EMG, ECG, peripheral skin temperature and skin conductance level, were acquired. Then, the degree of stress was assessed by synthetically those signals using fuzzy inference. From the fuzzy inference result, the parameters (amount of physiological change / amount of imposed stress) and (time to 25% recovery), which represent response and recovery respectively, were derived. We made a two-dimensional point graph using the response parameter as an abscissa and the recovery parameter as an ordinate for each subject.

• Asian-Australasian Journal of Animal Sciences
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• 제16권11호
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• pp.1599-1603
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• 2003

The physical feature, physiological character and behavior studies were conducted with fifteen newly collected gayals in Bandarban hill tract area of Bangladesh. Their morphology is different from domestic cattle. The range of pulse rate, body temperature and respiration rate were 47 to 75 per minute, 37.78 to $38.88^{\circ}C$ and 20 to 40 per minute, respectively. These physiological values vary with different age group and seasonal variation. In hematological feature, the average findings were RBC $7.01{\pm}0.52$ million/cu.mm, WBC $14.3{\pm}3.69$ thousand/cu.mm, hemoglobin concentration $9.81{\pm}2.25gm%$, PCV $35.86{\pm}3.68%$. In differential WBC count neutrophils $28.23{\pm}1.75%$, lymphocytes $62{\pm}2.05%$, monocytes $4.4{\pm}1.34%$, eosinophils $5{\pm}2.49%$ and basophils $0.4{\pm}0.51%$. In behavior study, the animal shows browsing nature on hill slopes. They are watchful in new environment, become excited and nervous with strangers. Heated female gayals response for mating with domestic bull.

• 수면정신생리
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• 제16권1호
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• pp.5-9
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• 2009

Relatively little is known about the neurobiology of insomnia, despite its wide prevalence and broad medical impact. Although much is still to be learned about the pathophysiology of the disorder, identification, systematic assessment, and appropriate treatment are clearly beneficial to patients. Recent research, using quantitative EEG, polysomnography (PSG), multiple sleep latency test (MSLT) and neuroimaging techniques, suggests that some broad areas can be identified as possible pathophysiological models. Sleep-wake homeostat model hypothesizes a failure in homeostatic regulation of sleep, an attenuated increase in sleep drive with time awake, and/or defective sensing of sleep need. Circadian clock model hypothesizes a dysfunctional circadian clock, resulting in changes in the timing of sleep-wake propensity that are incompatible with normal sleep. Intrinsic sleep-wake state mechanism model suggests that abnormal function of insomnia comprises the systems responsible for expression of the sleep states themselves. Extrinsic over-ride mechanism (stress-response) model suggests that insomnia reflects the consequences of overactivity of one of the systems considered "extrinsic" to normal sleep-wake control. Many current therapies for insomnia are based on these physiological models. Several attempts have been made to create a physiological model that would explain this disorder and could be used as a foundation for treatment. However, it appeared that no model can fully explain and clarify all aspects of insomnia. Future research should be necessary to expand our knowledge on the biological dimensions of insomnia.

• 한국의류학회지
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• 제37권2호
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• pp.235-245
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• 2013

Physiological responses and subjective sensations were evaluated for wearing protective welding clothing in consideration of the work environment for the shipbuilding industry. Experimental clothing was made of oxidant carbon nonwoven fabric (SW2) and oxidant carbon/p-aramid blended fabric (SW4). The values of all items in physiological responses were higher upon wearing oxidant carbon experimental clothing versus wearing oxidant carbon/p-aramid experimental clothing (p<.001). The results of the wearing evaluation in the welding work on-site showed that existing leather protective clothing had a very low satisfaction of permeability, weight sensation and wearing sensation. For the wearing sensation of experimental clothing with SW2, permeability and durability were poor and the pressure and weight sensation satisfaction was very high. In case of SW4, the satisfaction was very high in functional movement, pressure, weight sensation and management aspects; subsequently, the overall wearing satisfaction was very good.

• 대한의용생체공학회:의공학회지
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• 제12권4호
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• pp.235-242
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• 1991

This research has reported that the selection and assessment of treatment in anxiety disorders depend to a large extend on patient reports of somatic symptomatology. However, the correspondence between such reports and actual physiological data Is unknown as the physiological measures used were taken in laboratory. The purpose of the ambulatory momboring device is, therefore, to present for analysis physiological data derived from the sub jects during their daily activities. The physiological parameters of interest are heart rate, respiratory rate, skin conductance level/response, skin temperature, and activity level. This device had an microcomputer based data acquisition unit, Interfaced to it for the purpose of data collection. The data is collected usually over a period of 12 hours. The data from the ambulatory monitoring device can be used to assess the psychophysiology of anxiety in the field. The data from the device will also reveal if patients who report different sets of symptoms differ physiologically too. Thls will help physicians for the right kind of treatment and also solve the many uncertainties that have existed thus far in quantizing anxiety.

• Bulletin of the Korean Chemical Society
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• 제30권10호
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• pp.2318-2328
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• 2009

Massive deadenylation of adenine based-nucleosides induced by halogenated alkanes at the physiological condition have been observed. For the study of deadenylation effects by the different substituents and/or functionality in halogenated alkanes, diverse kinds of halogenated alkanes were incubated with adenine based-nucleosides (ddA, dA and adenosine) for 48 h at the physiological condition (pH 7.4, $37\;{^{\circ}C}$), which were analyzed by HPLC and further confirmed by LC-MS. Among the sixteen different halogenated alkanes, we observed massive deadenylation of nucleosides by 2-bromo-2-methylpropane, 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane. The order of deadenylation rate was highest in 2-bromo-2-methylpropane followed by 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane. In addition, time and dose response relationship of deadenylation in adenine based-nucleosides induced by 2-bromo-2-methylpropane, 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane at the physiological condition were investigated. In addition, deadenylation of calf thymus DNA induced by halogenated alkanes was also investigated. These results suggest that the toxic effect of certain halogenated alkanes might be from the depurination of nucleosides.

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.2949-2958
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• 2009

Massive deguanylation of guanine based-nucleosides induced by halogenated alkanes at the physiological condition have been observed. For the study of deguanylation effects by the different substituents and/or functionality in halogenated alkanes, diverse kinds of halogenated alkanes were incubated with guanine based-nucleosides (ddG, dG and guanosine) for 48 h at the physiological condition (pH 7.4, 37$^{\circ}C$), which were analyzed by HPLC and further confirmed by LC-MS. Among the sixteen different halogenated alkanes, we observed massive deguanylation of nucleosides by 2-bromo-2-methylpropane, 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane. The order of deguanylation rate was highest in 2-bromo-2-methylpropane followed by 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane. In addition, time and dose response relationship of deguanylation in guanine basednucleosides induced by 2-bromo-2-methylpropane, 2,3-dibromopropene, 2-bromopropane, bromoethane and 2-iodopropane at the physiological condition were investigated. Deguanylation of calf thymus DNA induced by halogenated alkanes was also investigated. These results suggest that the toxic effect of certain halogenated alkanes might be from the depurination of nucleosides.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.124-124
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• 2017

Cadmium (Cd) is of particular concern because of its widespread occurrence and high toxicity and may cause serious morpho-physiological and molecular abnormalities in in plants. The present study was performed to explore Cd-induced morpho-physiological alterations and their potentiality associated mechanisms in Sorghum bicolor leaves at the protein level. Ten-day-old sorghum seedlings were exposed to different concentrations (0, 100, and $150{\mu}M$) of $CdCl_2$, and different morpho-physiological responses were recorded. The effects of Cd exposure on protein expression patterns in S. bicolor were investigated using two-dimensional gel electrophoresis (2-DE) in samples derived from the leaves of both control and Cd-treated seedlings. The observed morphological changes revealed that the plants treated with Cd displayed dramatically altered shoot lengths, fresh weights, and relative water content. In addition, the concentration of Cd was markedly increased by treatment with Cd, and the amount of Cd taken up by the shoots was significantly and directly correlated with the applied level of Cd. Using the 2-DE method, a total of 33 differentially expressed protein spots were analyzed using MALDI-TOF/TOF MS. Of these, treatment with Cd resulted in significant increases in 15 proteins and decreases in 18 proteins. Significant changes were absorbed in the levels of proteins known to be involved in carbohydrate metabolism, transcriptional regulation, translation and stress responses. Proteomic results revealed that Cd stress had an inhibitory effect on carbon fixation, ATP production and the regulation of protein synthesis. In addition, the up-regulation of glutathione S-transferase and cytochrome P450 may play a significant role in Cd-related toxicity and stress responses. Our study provides insights into the integrated molecular mechanisms involved in response to Cd and the effects of Cd on the growth and physiological characteristics of sorghum seedlings. The upregulation of these stress-related genes may be candidates for further research and use in genetic manipulation of sorghum tolerance to Cd stress.

• 감성과학
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• 제27권1호
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• pp.3-12
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• 2024

본 연구는 정서 영상을 보며 웨어러블 기구로 측정된 생리적 반응과 정서평정을 분석하여 유발된 정서가 어떻게 표상되는지 알아보고자 하였다. 연구 목적을 위해, 공유된 데이터셋을 다차원척도법(multidimensional scaling)을 통해 정서 영상, 생리적 반응 및 정서 평정을 2차원에 표상하였다. 또한, 참가자간 분류분석(cross-participant classification)을 활용해 참가자 간 정서표상이 얼마나 일관적인지 분석하였다. 추가적으로, 참가자들의 반응이 유사한 정도가 각 정서 조건 별로 다른지 확인하기 위해, 정서 영상 별 정확분류와 오분류를 혼동행렬(confusion matrix)을 통해 탐색하였다. 다차원척도법 결과, 정서 영상들과 정서 평정의 위치가 기존 이론과 부합하게 정서가 및 각성가 벡터에 따라 표상되어, Russell(1980)의 핵심정서이론을 지지하는 것을 확인했다. 표상된 생리적 반응 벡터를 통해, 심박률 증가-저각성, 높은 심박률변산성-부정정서 고각성, 피부전기활동 증가-부정정서 저각성의 관계를 시각화했다. 행동 및 생리 데이터로 학습한 참가자간 분류분석 결과, 평균 정확도가 우연수준보다 높았다. 이는 동일한 영상에 대한 참가자들의 공유되는 정서 표상이 있음을 지지한다. 혼동행렬표를 통해, 저각성 긍정정서로 표상된 감탄, 열정, 그리고 선호는 상대적으로 잘 분류되지 않았고, 서로 더 많이 오분류되는 것을 확인하였다. 다변량 분석인 다차원척도법과 분류분석을 통해, 본 연구는 영상 자극에 웨어러블 기구로 측정한 생리적 반응과 정서 평정도 핵심 정서 이론과 부합하는 결과를 얻은 것에 의의가 있다.