• Membrane Journal
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• v.7 no.4
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• pp.183-190
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• 1997

Composite membranes were prepared by the deposition of pentafluoropyridine(PFP) or pentafluorotoluene(PFT) plasma films onto porous Celgard and nonporous poly(dimethylsiloxane) [PDMS] films. Gas permeation measurements for the composite membranes were made in the temperature range of 35$^{\circ}$C to 75 $^{\circ}$C and the solubilities in plasma polymers were measured using a Cahn Microbalance. The permeability coefficients of plasma polymers obeyed the Arrhenius relationship fairly wall. Activation energies for permeation in the plasma films increased with the size of penetrant molecules. The activation energy of plasma polymers was much lower than that of commonly used perfluoropolymers. This difference was proved to be attributable to the much lower heat of solutions of the plasma polymers compared to perfluoropolymers. The diffusion activation energies were comparable with each other.

• Journal of Food Hygiene and Safety
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• v.34 no.2
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• pp.124-134
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• 2019

An analytical method was developed for the determination of broflanilide and its metabolites in agricultural products. Sample preparation was conducted using the QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method and LC-MS/MS (liquid chromatograph-tandem mass spectrometer). The analytes were extracted with acetonitrile and cleaned up using d-SPE (dispersive solid phase extraction) sorbents such as anhydrous magnesium sulfate, primary secondary amine (PSA) and octadecyl ($C_{18}$). The limit of detection (LOD) and quantification (LOQ) were 0.004 and 0.01 mg/kg, respectively. The recovery results for broflanilide, DM-8007 and S(PFP-OH)-8007 ranged between 90.7 to 113.7%, 88.2 to 109.7% and 79.8 to 97.8% at different concentration levels (LOQ, 10LOQ, 50LOQ) with relative standard deviation (RSD) less than 8.8%. The inter-laboratory study recovery results for broflanilide and DM-8007 and S (PFP-OH)-8007 ranged between 86.3 to 109.1%, 87.8 to 109.7% and 78.8 to 102.1%, and RSD values were also below 21%. All values were consistent with the criteria ranges requested in the Codex guidelines (CAC/GL 40-1993, 2003) and the Food and Drug Safety Evaluation guidelines (2016). Therefore, the proposed analytical method was accurate, effective and sensitive for broflanilide determination in agricultural commodities.

• Journal of the korean veterinary medical association
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• v.25 no.10
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• pp.595-606
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• 1989

항원제시세포(APC)와 보조T세포 간의 협력작용에 의하여 활성화된 작동세포(NK세포, CTL, K세포, 대식세포, 과립구 등)의 종양세포, 이식장기 및 세포내기생세균에 감염된 각종 세포에 대한 세포독성작용은 생체방어를 위한 중요한 세포성면역기전이다. 지난 몇 년간 세포성면역기전에 관한 많은 연구에도 불구하고 T림파구매개성 세포독성작용의 면역생물학적기전은 확실히 밝혀있지 않다. 지금까지 알려진 중요한 연구내용을 요약하면 다음과 같다. 1. 세포독성작용을 나타내는 작동세포로는 NK세포, CTL, K세포, 대식세포/단핵구 및 과립구가 있다. 2. T세포의 세포표면항원분자군(CD)으로는 $CD_{2},\;CD_{3},\;CD_{4}[Ly_{3}T_{4}],\;CD_{5}[=Ly_{1}],\;CD_{7},\;CD_{8}[Ly_{2,3}]$가 있으며 $CD_{4}$는 보조Ttpvhdml 특이마커이고 $CD_{8}$는 세포독성 T세포 및 억압T세포의 특이마커이다. 주요 T세포수용체(TCR)는 $CD_{4}$ 또는 $CD_{8}$ 분자와 가까이 연합된 이향체($TCR-{\alpha}{\beta}/TCR-{\gamma}{\delta}$이며 보조 T세포 $CD_{4}$(마우스 $L_{3}T_{4}$)는 수용체와 연합되어 있는반면 억압 T세포 $CD_{8}(Ly+_{2,3})$는 항원수용체와 연합되어 있다. 3. T세포는 Ti-$CD_{3}$(항원/MHC) 복합체를 통한 '항원가교'에 의한 자극(항원인식)과 $CD_{2}$를 통한 비특이경로에 의하여 활성화(분화증식)된다. 비특이경로를 통한 활성경로에서 T세포($CD_{4}$ 및 $CD_{8}$)가 활성화되기 위하여는 보조T세포가 생산하는 IL-2을 요구하며 IL-2의 자극으로 분화증식된 $CD_{8}$는 세포독성능을 나타내지만 $CD_{4}^{+}$는 여전히 세포독성능을 나타내지 못한다. 4. 보조T세포는 class II MHC분자와 연합된 항원을 식별하는 반면 세포독성T세포는 class I MHC 분자와 연합된 항원을 식별한다. 5. 림파구 매개성 세포독성은 접촉(conjugati-on), 탈분극(depolarization), 용해계획(progra-mming), 용해(lysis) 및 재순환(recycling)의 단계를 거쳐 진행된다. 6. 표적세포살해매체로는 perforin / PFP / cy-tolysin, lymphopores, lymphotoxins, protone, cytolytic enzymes가 알려졌으며 세포독성작용은 이들 이외에도 여러 가지 매체를 통한 복합작용으로 추정된다. 7. CTL 매개성 표적세포의 주요 대사변화는 actomyocin ATPase의 증가, phosphocreatine과 ATPase의 소모, ATP 의존성 $Na^{+}/K^{+}$ 펌프작용의 중지, ATP 의존성 $Ca^{2+}$ 유출감소 및 세포내 축적이 관찰된다. 8. $Ca^{2+}$의 축적으로 세포막 교질 침투손상을 주어 수분의 유입을 증가시킴으로써 수포형성, 핵붕괴, 사립체팽화 및 정상세포 구조상실(Zeiosis)이 있다. 결론적으로 CTL 매개성 세포독성작용은 PFP, LT, TNF, 유사 TNF / LT 및 기타 매체를 통한 복합작용이며 세포살해기전은 지속적 대사소모와 정형적 세포구조(핵 및 세포질)의 파괴에 의한 것이다.

• Analytical Science and Technology
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• v.12 no.6
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• pp.571-576
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• 1999

Screening method for NSAIDs (Hon-Steroidal Anti-Inflammatory Drugs) in urine was developed using GC/NCI-MS. Derivatized six fenamates with pentafluoropropionic anhydride showed high sensitivity in NCI-MS. The conditions of the derivatization reaction and chromatographic conditions were established for screening with a trace analysis. Limit of detection was in the range of 4-25 pg/mL. This method may be used to the equine doping analysis for NSAIDs and forensic analysis.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.14 no.4
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• pp.77-82
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• 2000

This paper describes the self healing characteristics of a metalized polypropylene film(MPPF) by voids under a.c condition. PDIVs were increased with the number of pre-self healing due to void defects, and several pre-self healing events took place at lower voltage than the critical breakdown voltage of a PPF. Self healing mainly occurred at pin tips, wrinkle sides, and cross points of wrinkles, and the main self healing voltage was increased with PPF thickness. The burn out area at self healing was increased with the applied voltage, and the peak currents in a grounding conductor at self healing was also increased with the applied voltage.

• Journal of Ocean Engineering and Technology
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• v.25 no.3
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• pp.66-72
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• 2011

This is the fourth of a series of companion papers dealing with the mechanical property reductions of various marine structural steels. Even though a reduction of the elastic modulus according to temperature increases has not been obtained from experiments, high temperature experiments from room temperature to $900^{\circ}C$ revealed that initial the yield strength and tensile strength are both seriously degraded. The mechanical properties obtained from high temperature experiments are compared with those from EC3 (Eurocode 3). It is found that the high temperature test results generally comply with the prediction values by EC3. Based on the prediction of EC3, time domain nonlinear finite element analyses were carried out for a blast wall installed on a real FPSO. After applying the reduced mechanical properties, corresponding to $600^{\circ}C$ to the FE model of the blast wall, more than three times the deflections were observed and it was observed that most structural parts experience plastic deformations exceeding the reduced yield strength at the high temperature. It is noted that a protection facility such as PFP (passive fire protection) should be required for structures likely to be directly exposed to fire and explosion accident.

• Journal of The Korea Institute of Healthcare Architecture
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• v.17 no.4
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• pp.7-14
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• 2011

This paper is intended to suggest some reference materials for future elderly housing design, especially smart home, in Korea, by reviewing the elements and applications of smart home concept for older adults in USA. Research method includes collecting materials by attending the regular SmartHome$^{(R)}$ part meeting, the navigation of related homepages, and the analysis of collected materials. Current researches in Korea look initial stage and show some general principles without practical concept & technologies of elderly facilities. SeniorSmart$^{(R)}$ Center in USA started on August 2007 with the 3 parts of SmartHOME$^{(R)}$, SmartWHEELS$^{(R)}$ and SmartBRAIN$^{(R)}$. The Center has been doing various multidisciplinary research projects but slowing down the planned processes due to national economic recession. The major researches of SmartHome$^{(R)}$ part can be summarized as follows; CS-PFP( Continuous Scale Physical Function Performance) laboratory is being in operation to help older adults and families make the difficult decision regarding the ability and safety to live independently. Three levels of necessary laboratories from uninhabited space to senior living environment were accommodated for field research. As core technologies of SmartHome$^{(R)}$, predicting & warning system of fall risk on recognizing gait signature patterns to identify any deviation from the normal patterns of the older adults, home monitoring system which will send alerts to a specified relative and/or health care professional when vital signs of the older adults will not be within normal parameters, and Mobility & Research Clinic for evaluating, treating the older adults & multidisciplinary research are under development. SmartHome$^{(R)}$ has made collaborative research agreements for field laboratory with various retirement communities and also is continuing to work for experimental software engineering with the Fraunhofer Institute, Germany.

• Korean Journal of Veterinary Research
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• v.43 no.1
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• pp.77-86
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• 2003

Pullorum disease due to Salmonella enterica subspecies enterica bioserovar Pullorum (S. pullorum) is reported to be an endemic disease in domestic poultry flocks. The pulsed-field gel electrophoresis (PFGE) subtyping method was used to assess the extent of genetic diversity and clonality of most of salmonella serotypes and other diverse bacterial species from animals and environmental samples in worldwide. Nowadays, PFGE has already been evaluated as a gold standards for molecular subtyping of salmonella serotypes compared with other molecular analysis methods. PFGE of XbaI digested chromosomal DNA from 23 strains of S. pullorum gave 5 distinctive pulsotypes (from SXPI to SXPV) with 5% confidence range of Dice coefficients, indicating that PFGE is very discriminative and that multiple clones of S. pullorum have been existed and diffused all of domestic poultry flocks industries since 1995. Two dominant pulsogroups (SXA & SXB) appeared as a major clones in this country, because they had consistently been recovered from diverse sources including both chicken organs and raw feed materials between 1995 and 1998. In addition, the matching percentage of PFGE profiles (PFP) among strains from both chickens and feed ingredients provides indirect evidence of the possible transmission of pullorum disease from contaminated raw feed ingredients for chicken production. In calculating of discrimination index (DI) for PFGE method by Simpson's index, DI was appeared as 0.917. Therefore, this index suggested that the present PFGE would seem to be a desirable and confident molecular typing method for S. pullorum strains. To our knowledge for pullorum disease, this is the first study to compare S. pullorum strains from chicken organs and feed samples using the PFGE.

• Computational Structural Engineering
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• v.7 no.1
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• pp.109-116
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• 1994

In this paper, various reliability analysis methods for calculating a probability of failure are investigated for their accuracy and efficiency. Crude Monte Carlo method is used as a basis for the comparison of various numerical results. For the sampling methods, Importance Sampling method and Directional Simulation method are considered for overcoming a drawback of Crude Monte Carlo method. For the approximate methods, conventional Rackwitz-Fiessler method. 3-parameter Chen-Lind method, and Rosenblatt transformation method are compared on the basis of First order reliability method. As a Second-order reliability method, Curvature-Fitting paraboloid method, Point-fitting paraboloid method, and Log-likelihood function method are explored in order to verify the accuracy of the reliability calculation results. These methods mentioned above would have some difficulty unless the limit state equation is expressed explicitly in terms of random design variables. Thus, there is a need to develop some general reliability methods for the case where an implicit limit state equation is given. For this purpose, Response surface method is used where the limit state equation is approximated by regression analysis of the response surface outcomes resulted from the structural analysis. From the application of these various reliability methods to three examples, it is found that Directional Simulation method and Response Surface method are very efficient and recommendable for the general reliability analysis problem cases.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.4
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• pp.67-75
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• 2016

Purpose: The purpose of this study was to compare Hip-Knee-Ankle(HKA) angle and muscle activation ratio between vastus medialis(VM), rectus femoris(RF), and vastus lateralis (VL), and by this, to examine their relationship. It is aimed to explore how the activation ratio among the muscles involved in patellofemoral kinetics would vary in relation with the frontal alignment of the lower extremity. Subjects and Methods: 26 healthy subjects were recruited for the study. The HKA angles were measured with radiograph. The VM, RF, VL muscle activation level were measured by surface electromyography while each participant performed 4 different types of movement (isometric knee extension, squat, ambulation, step-up) and VM/RF, VM/VL, RF/VL ratios were calculated. Pearson correlation was used to estimate the relationship between the HKA angle and the muscle ratio. Results: There was significant moderate correlation between HKA angle and VM: RF on the left side during ambulation (p<0.05). Moderate correlations were also observed during step-up and squat with less significance (p<0.1). Conclusion: The frontal alignment of the knee measured by the HKA angle was conditionally associated with muscle activation ratio between VM and RF (VM:RF); On the left, during ambulation, step-up, and squat, the more valgus knee tended to correlate with the more VM muscle activation ratio, which is expected to induce more stabilizing effect to the patella and its tracking. It suggests that the frontal alignement measured by the HKA-angle can affect PF kinetics. It also indicates a possibility that increase in valgus alignment of the knee, by the HKA measurement, may not act unfavorably to generate PFP.