• Title/Summary/Keyword: PED

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The N-terminal Region of the Porcine Epidemic Diarrhea Virus Spike Protein is Important for the Receptor Binding (PED 바이러스 Spike 단백질의 세포 수용체 결합 부위 확인)

  • Lee, Dong-Kyu;Cha, Se-Yeoun;Lee, Chang-Hee
    • Microbiology and Biotechnology Letters
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    • v.39 no.2
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    • pp.140-145
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    • 2011
  • Porcine epidemic diarrhea virus (PEDV) infection causes acute enteritis with lethal watery diarrhea resulting in a high mortality rate in piglets. As with the other members of group 1 coronaviruses, PEDV also utilizes the host aminopeptidase N (APN) as the major cellular receptor for entry into target cells. The coronavirus spike (S) protein is known to interact with the cellular surface for viral attachment and the S1 domain of all characterized coronaviruses contains a receptor-binding domain (RBD) that mediates a specific high-affinity interaction with their respective cellular receptors. Although the RBDs of several coronaviruses have been mapped, the location of the PEDV RBD has to date not been defined. As a first step toward the identification of the region of the S protein of the PEDV that is critical for recognition with the cellular receptor, we generated a series of S1-truncated variants and examined their abilities to bind to the porcine APN (pAPN) receptor. Our data indicate that the N-terminus of the S1 domain is required for pAPN association. The results from the present study may assist in our understanding of the molecular interactions between the PEDV S protein and the pAPN receptor.

Soil Characteristics on the Fluvial Surface in the Basin of Kyeongan-cheon (Stream) (경안천 유역 하성면에 발달한 토양 특성)

  • Kang, Young-Pork;Sin, Kwang-Sig
    • Journal of the Korean earth science society
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    • v.27 no.5
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    • pp.548-556
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    • 2006
  • The purpose of this study is to clarify the relict landform development of fluvial terrace and the soil characteristics occurring on the fluvial deposits. The physico-chemical properties of soil that are developed on terrace deposits and X-ray diffraction analysis of clay were investigated specifically. The horizon of $A_1$ consists of silt loam with reddish-brown color (5YR4/3). Its soil structures is a weak, fine, subangular, and blocky, breaking to granular. The horizon of $B_{1t}\;and\;B_{2t}$ are silt clay with either a yellowish red (5YR5/6), bright red (2.5YR4/6) color. This soil structure is weak, subangular, and blocky, with thin discontinuous bright red (2.5YR4/6) clay cutans and soft manganese concretions. This red soil structure is made on heavy-textures. It is packed compactly with parent materials of high fluvial surface sediments, and usually has a $A_1-B_{1t}-B_{2t}-C$ profile, from top to bottom. In most cases, clay accumulation in the B-horizon and clay cutans on ped surfaces are observed, which means the argillic horizon has formed. The soils derived from fluvial surface deposits are associated with soils. The soils on the high fluvial surface are considered to be a kind of paleo-red soil which were developed by strong desilicification and rubefaction, and strong leaching of bases under warmer bio-climatic condition during the old Pleistocene period. According to these morphological and anlaytical characteristics,geomorphological features and bio-climatic conditions under which the soil have developed on the high terrace sediment indicate that the soil should be classified as paleo-red soils.

Genesis and Classification of the Red-Yellow Podzolic soils derived from Residuum on Acidic and Intermediate Rocks -Vol. 1 (Jeonnam series) (산성암(酸性岩) 및 중성암(中性岩)의 잔적층에 발달(發達)된 적황색토(赤黃色土)의 생성(生成) 및 분류(分類) -제(第) 1 보(報) (전남통(全南統)에 관(關)하여))

  • Um, Ki Tae
    • Korean Journal of Soil Science and Fertilizer
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    • v.4 no.2
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    • pp.187-192
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    • 1971
  • This paper deals mainly with the genesis and classification of the Jeonnam series. These soils have brown to dark brown silt loam and silty clay loam A horizon(strong brown or reddish brown where eroded). Argillic B horizons are dominantly red or yellowish red silty clay loam to silty clay with moderately developed subangular blocky structure and with thin clay cutans on the ped faces. The C horizons are strongly and very deeply weathered strong brown, yellowish brown, pale brown and reddish yellow silty clay loam and sandy loam granitic saprolite. Content of clay increases with depth to a maximum between 100cm. Percolating water seems to be responsible for transportation and oriented deposition of clay. Chemically, soil reaction is strongly acid to medium acid throughout the profile. The content of organic matter is 1 to 2 percent, and decreases regularly with depth. Base saturation is low, based on amount of extractable cations. Characterisltically the Jeonnam series are similar to Red-Yellow Podzolic soils of the United States and are similar to Red-Yellow soils of the Japan. In the writer's opinion the Jeonnam soils are classified as Red Yellow soils. According to USDA 7th approximation, this soil can be classified as Typic Hapludults and in the FAO/UNESCO World Soil Map as Helvic Acrisols.

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Developing Yellow Dust and Fine Particulate Masks for Children (어린이용 황사 및 미세먼지 마스크 개발 연구)

  • Kim, Hyunwook;Seo, Hyekyung;Myong, Jun-Pyo;Yoon, Jong-Seo;Song, Yeunkun;Kim, Choongbuem
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.26 no.3
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    • pp.350-366
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    • 2016
  • Objectives: No 3D anthropometric analyses have been conducted for Korean children's faces for the purpose of designing respiratory protective devices. The aim of this study was to develop masks against yellow dust and fine particulates, particularly for children in Korea. Methods: This study utilized a 3D scanning method to obtain 16 facial anthropometric data from children, ages of 5 to 13 years old. A total of 144 boys and girls were recruited from the kindergarten, elementary schools and middle schools in Seoul. With facial dimensions obtained, cluster analysis was performed to categorize them into similar facial groups. For each cluster, an optimal mask was designed and manufactured using a 3D printer. In addition, lung function data were obtained from 62 subjects and compared with those of normal adults. The pulmonary physiological results were subsequently used to suggest a test method for mask certification. Results: Facial shapes were classified into tree clusters: small, medium, and large. The face width and length for the first group were small with high nosal protrusion. The face width and length for the second group were the largest among the three clusters. The third group had the largest angle of nose root - gnathion(n-prn-gn). Age was the most significant variable in the facial dimensions. Children's pulmonary physiological capacity was about 60% of adults' capacity. The results of fit test using the prototype masks developed showed very good fits for children. Conclusions: For Korean children, three mask sizes will be sufficient and practical for providing protection against yellow dust and fine particulates. Anthropometric data obtained using digitalized 3D face analysis can be very effective for designing respiratory devices. 3D images can be accurate and easily measured for multiple dimensions, particularly for curved areas of the face. It is imperative to adopt different test methods for certifying respiratory protective devices for children, since their pulmonary physiological capacity is inferior compared with that of adults.

Investigation of diseases incident to pre- and pos-weaning piglets (포유 및 이유자돈의 질병발생 동향)

  • Oh, Myong-ho;Eun, Gil-soo;Kim, Hong-jib;Kyon, Young-bang
    • Korean Journal of Veterinary Research
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    • v.40 no.1
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    • pp.173-186
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    • 2000
  • This experiment was carried out to investigate the tendency of incident diseases in pre- and post- weaning piglets which ages were 1 to 7 weeks old by laboratory diagnosis and in order to minimize death in preweaning piglets and of stunted growth in postweaning piglets. The result of this experiment used as the basic data for the preventive programs in pre- and post- weaning piglets and were as follows: 23 different diseases diagnosed in 331 cases were studied in relation to age, season, and etiology. The most prevelent diseases of pre- and post- weaning piglet were Colibacillosis(79 case, 23.9%) and the major diseases were Salmonellosis(44 cases, 13.3%), Anemia(37 cases, 11.2%). Unknown viral disease(20 case, 6.1%), Rota viral infection(19 case, 5.8%), Porcine reproductive & respiratory syndrome(PRRS; 15 case 4.5%), Transmissible gastroenteritis(TGE; 12 case, 3.6%). The gastrointestinal disease, such as Colibacillosis, Salmonellosis, Swine dysentery, Clostridial infection, Rotaviral infection, TGE, Porcine epidemic diarrhea(PED) and Ballantidiosis occured pro- dominently in the period of pre- and post- weaning, which were 178 cases(53.8%) and not related to occurrence according to age and season. The respiratory diseases were Atrophic rhinitis(AR), Swine enzootic pneumonia, Pneumonic pasteurellosis, Pleuropneumonia, Branchopneumonia, PRRS and which were 48 cases(14.5%) and higher prevalent in spring and summer. The viral diseases was 73 cases(22.1%) that occurred in the period of 5 weeks piglet and prevalent mainly in spring. The bacterial diseases were 188 cases(56.8%) that were not related to occurrence according to age and season. Salmonellosis was prevalent in 3 to 5 weeks piglet and mainly occurred in summer. Viral septicemia and rotaviral infection occurred after 5 weeks piglets intensively and 3 to 5 weeks, respectively. And the both occurred without relation with season. PRRS occurred after 4 weeks piglet and prevalent in summer. TGE occurred 1 to 7 days old piglets and prevalent in spring and winter. Hematologic values of anemia was decrease in number of Red Blood Cell, concentration of Hemoglobin and Hematocrit. Amikacin, cephalothin, colistin, norfloxacin were effective to E coli, and amikacin, cephalothin, nortloxacin, neomycin were effective to Salmonellra spp. but clindamycin, erythromycin, penicillin, sulfonamides were resistant to E coli and Salmonella spp.

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Analysis of 3D Facial dimensions and Pulmonary Capacity of Korean Children for Designing of Children's Dust Masks (어린이 보건용 마스크의 인증기준 마련을 위한 3D 얼굴치수 및 호흡량 연구)

  • Seo, Hyekyung;Kim, Jennifer Ivy;Yoon, Jong-Seo;Shin, Donghoon;Kim, Hyunwook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.4
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    • pp.269-282
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    • 2017
  • Objectives: Currently, masks against yellow dust and fine particulates are being certified with no consideration of facial dimensional variations among children and adults. The aims of this study were to develop masks against yellow dust and fine particulates for children in Korea and provide basic data to suggest new test methods for mask certification that consider the breathing capacity of children. Methods: A total of 730 study participants aged from six to 13 years old were recruited in the Seoul, Gyeonggi, and Incheon region. This study used a 3D scanning instrument to obtain 16 facial anthropometric data points. Literature reviews, a comparison of breathing capacity between adults and children, and analysis of children's pulmonary physiological data were conducted in order to suggest new test standards for certifying children's masks against yellow dust and fine particulates. In addition, types of children's masks, choice of wearing a mask or not, and reasons for not wearing masks were surveyed. Results: Based on a clustering analysis of participants' facial dimensions, facial shapes were classified into three groups: small, medium, and large. The sizes of children's masks were subtracted by using 3D sketch techniques(Large: $121.25mm{\times}89.46mm$, Medium: $111.92mm{\times}78.55mm$, Small: $102.13mm{\times}72.87mm$). In certifying children's mask, flow rates of $60{\ell}/m$ for the filtering efficiency test and $20{\ell}/m$ for the breathing resistance test were recommended, since children's pulmonary physiological capacity is about 60-70% of adults' pulmonary capacity. Conclusions: The results of this study suggest that three mask sizes for children would be sufficient and practical for providing protection against yellow dust and fine particulates. Revising current test methods for certifying respiratory protective devices for children is important, since children's pulmonary physiological capacity substantially differs from that of adults. Therefore, it is recommended that new test standards for certifying children's masks be promulgated in the near future.

Microbiological Characteristics of Gamma Irradiated and Low-Salted Fermented Squid (감마선 조사된 저염 오징어젓갈 발효의 미생물균총 특성)

  • Kim, Dong-Ho;Kim, Jae-Hun;Yook, Hong-Sun;Ahn, Hyun-Joo;Kim, Jung-Ok;Sohn, Cheon-Bae;Byun, Myung-Woo
    • Korean Journal of Food Science and Technology
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    • v.31 no.6
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    • pp.1619-1627
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    • 1999
  • Microbiological characteristics of gamma irradiated low salt squid Jeot-gal were examined. Following the fermentation periods, total bacterial cell, Lactobacillus spp., Staphylococcus spp., Streptococcus spp., Pseudomonas spp. and yeast cell number were counted on their selective media and some acid forming bacteria and Pseudomonas spp. were identified. As the gamma irradiation dose increased, the microbial density of early fermentation phase was reduced and the growth rate was delayed. The repression effects on microbiological growth by gamma irradiation were to be higher as salt concentration increased. Adequate conditions of salt concentration and gamma irradiation for low-salt squid Jeot-gal preparation were 10% and 10 kGy, respectively. Lactobacillus sp. 2, Micrococcus varians and Streptococcus sp. I were isolated from 5% salt containing squid Jeot-gal, and Micrococcus morrhuae was from 20% only while Lactobacillus plantarum and Lactobacillus brevis were widespread. Lactobacillus brevis, Pediococcus halophilus and Pseudomonas diminuta were sensitive and Lactobacillus plantarum, Micrococcus morrhuae and Pseudomonas sp. 3 were resistant to gamma irradiation. The diversity of microflora decreased as salt concentration decreased and gamma irradiation dose increased.

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A Priority Signal Control Strategy for Vulnerable Considering Traffic Flow - Focusing on crosswalks in coordinated arterial sections - (교통흐름을 고려한 교통약자 우선신호 운영방안 연구 -연동화 가로구간내 횡단보도를 대상으로-)

  • Ryu, Junil;Kim, Wonchul;Kim, Hyoungchul
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.13 no.4
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    • pp.12-19
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    • 2014
  • A signal plan focused on vehicle traffic could easily overlook vulnerable priority signals, although the importance of vulnerable movements is increasingly recognized in recent years. Especially, the vulnerable are sometimes faced with dangerous situations when crossing roads with a signal plan based on design values of average, non-vulnerable persons. This study is focused on how to minimize the vehicle delay while simultaneously considering traffic flow and providing traffic safety by increasing road crossing time for pedestrians. For this purpose, a priority signal control strategy for the vulnerable, considering vehicle traffic flow, has been tested. Practical implication and a microscopic computer simulation has shown that the proposed method could provide a small decrease (about 6.2%) in pedestrian delay, a small increase (about 8.5~13.3%) in travel speed of passing traffic, and a considerable decrease (16.2~26.9%) in vehicle travel time. These findings suggest that the proposed signal control strategy could increase pedestrian safety and diminish delay of vehicle travel.

Contactless User Identification System using Multi-channel Palm Images Facilitated by Triple Attention U-Net and CNN Classifier Ensemble Models

  • Kim, Inki;Kim, Beomjun;Woo, Sunghee;Gwak, Jeonghwan
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.3
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    • pp.33-43
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    • 2022
  • In this paper, we propose an ensemble model facilitated by multi-channel palm images with attention U-Net models and pretrained convolutional neural networks (CNNs) for establishing a contactless palm-based user identification system using conventional inexpensive camera sensors. Attention U-Net models are used to extract the areas of interest including hands (i.e., with fingers), palms (i.e., without fingers) and palm lines, which are combined to generate three channels being ped into the ensemble classifier. Then, the proposed palm information-based user identification system predicts the class using the classifier ensemble with three outperforming pre-trained CNN models. The proposed model demonstrates that the proposed model could achieve the classification accuracy, precision, recall, F1-score of 98.60%, 98.61%, 98.61%, 98.61% respectively, which indicate that the proposed model is effective even though we are using very cheap and inexpensive image sensors. We believe that in this COVID-19 pandemic circumstances, the proposed palm-based contactless user identification system can be an alternative, with high safety and reliability, compared with currently overwhelming contact-based systems.

A Study on characteristics of planosols in korea -Part I Yeongog series (우리나라에 분포(分布)된 반층토(盤層土)의 특성(特性)에 관(關)한 연구(硏究) -제(第)1보(報) 연용통(延谷統)에 관(關)하여)

  • Um, Ki Tae;Cho, Seong Jin
    • Korean Journal of Soil Science and Fertilizer
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    • v.8 no.2
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    • pp.45-51
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    • 1975
  • The morphological, physical, chemical, and mineralogical characteristics of planosols in Korea were studied in an effort to establish the suitabilition of the planosols for agricultural development. The Yeongog series which are planosols were established in Korea. Results from the Yeongog series are briefly as follows : 1. Morphologically, the surface soils are brown to dark brown friable loam and subsoils are of varied colors but mainly are dark brown, black and pale brown mottles. The texture of these horizons are silty clay loam with moderate to strong platy structure and clay cutans are on the ped faces. The consistences of these horizons are extremely compact and hard when moist and sticky, plastic when wet. The substrata show varied soil colors and loam to clay loam. 2. Physically, the clay content of the Yeongog soils is highest in the subsoils and gradually decreases below the subsoils. Water holding capacity and bulk desity is higher than in other mineral soils. 3. Chemically, the organic matter content is low and soil reaction ranges from very strongly to strongly acid. The cation exchange capacity is medium and base saturation a high. Active iron, easily reducible manganese and available silicate are high compared with normal soils. 4. In chemical composition of clay fraction of the Yeongog series, sesquioxide ratio, $Fe_2O_3$, $K_2O$ and MgO are high. The cation exchange capacity of the clay fraction is also very high. 5. The clay minerals in Yeongog series are mainly kaoline, vermiculite with Al interlayers and illite. The quarts, primary minerals are in the Yeongog soils. 6. These soils are formed in a warm, humid climate under native grasses on the terraces and rolling or hilly footslopes. In soil classification, the Yeongog soils are classified planosols with claypan. According to 7th approximation system in U.S.A., the Yeongog series are classified as Fragiudalfs because they have an argillic horizon, a hard pan and a high base saturation which is more than 35 percent and classified as Eutric Planosols by FAO/UNESCO classification system.

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