• Title/Summary/Keyword: PDD

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Design and evaluation of light source for photodynamic diagnosis of cancer (광역학적 암진단을 위한 광원장치의 설계 및 평가)

  • Lim, Hyun-Soo
    • Proceedings of the KIEE Conference
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    • 2007.04a
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    • pp.73-76
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    • 2007
  • Photodynamic diagnosis(PDD) is a method to diagnose the possibility of cancer, both by the principle that if a photosensitizer is injected into an organic tissue, it is accumulated in the tissue of a malignant tumor selectively after a specific period, and by a comparison of the intensity of the fluorescence of normal tissue with abnormal tissue after investigating the excitation light of a tissue with accumulated photosensitizer. Since the selection of the wavelength band of excitation light has an interrelation with fluorescence generation according to the selection of a photosencitizer, it plays an important role in POD. This study aims at designing and evaluating light source devices that can stably generate light with various kinds of wavelengths In order to make possible PDD using a photosensitizer and diagnosis using auto-fluorescence. The light source device was a Xenon lamp and filter wheel, composed of an optical output control through Iris and filters with several wavelength bands It also makes the inducement of auto-fluorescence possible because it is designed to generate a wavelength band of 380-400. The transmission part of the light source was, developed to enhance the efficiency of light transmission. To evaluate this light source device, the characteristics of the light output and wavelength band were verified. To validate the capability of this device as PDD the detection of auto-fluorescence using mouse was performed.

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The Korean Practice Parameter for the Treatment of Pervasive Developmental Disorders : Diagnosis and Assessment (전반적 발달장애의 한국형 치료 권고안 : 진단 및 평가)

  • Yoo, Hee-Jeong;Cho, In-Hee;Koo, Young-Jin;Yoo, Han-Ik;Son, Jung-Woo;Chung, Un-Sun;Ahn, Joung-Sook;Ahn, Dong-Hyun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.18 no.2
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    • pp.97-108
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    • 2007
  • Multiple areas of development are affected in pervasive developmental disorders(PDD), and assessments of various aspects of behavior and development are essential for diagnosis. The object of this review is to provide the practical guidelines for the assessment of core features of PDD, including abnormalities in communication, social interaction, and repetitive and stereotyped behavior. It covers the issues of differential diagnosis within and outside the PDD category, standardized diagnostic tools, assessment of intellectual and language functions, and the early diagnosis of PDD in infancy. This guideline also stresses the process of medical and neurological evaluation for proper diagnosis of PDD.

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Study on Variation of Depth Dose Curves by the Strong Magnetic Fields : Monte Carlo Calculation for 10 MV X-rays (강자기장에 의한 깊이선량율(PDD) 변화에 관한 연구 : 10 MV 광자선에 대한 몬테칼로 계산)

  • 정동혁;김진기;김정기;신교철;김기환;김성규;김진영;오영기;지영훈
    • Progress in Medical Physics
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    • v.14 no.4
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    • pp.234-239
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    • 2003
  • We examined the variation of percent depth dose (PDD) curves for 10 MV X-rays in the presence of magnetic fields. The EGS4 Monte Carlo code was applied and modified to take account of the effect of electron deflection under magnetic field was used. We defined and tested DI (dose improvement) and DR (dose reduction) to describe variation of PDD curves under various magnetic fields. For a magnetic field of 3 T applied at the depth region of 5-10 cm and field size of 10${\times}$10 $\textrm{cm}^2$, the DI is 1.56 (56% improvement) and DR is 0.68 (32% reduction). We explained the results from the Lorentz law and the concept of electron equilibrium. We suggested that the dose optimization in radiotherapy can be achieved from using the characteristics of dose distributions under magnetic fields.

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Characteristics of Insulation Aging in 4.16kV Motor Stator Windings (4.16kV 전동기 고정자 권선의 절연열화 특성)

  • Kim, Hee-Dong;Kong, Tae-Sik
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.1381_1382
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    • 2009
  • Nondestructive tests were performed on two 4.16kV motors. Epoxy-mica coupler(80pF) was connected to 4.16 kV motor stator windings. The voltage applied to the stator windings was 2.4 kV, 3.0kV, 3.5kV and 4.16kV, respectively. Digital partial discharge detector(PDD) and turbine generator analyzer(TGA) were used to measure partial discharge(PD) activity. TGA summarizes each plot with two quantities such as the normalized quantity number(NQN) and the peak PD magnitude(Qm). The PD levels in pC were measured with PDD. PD patterns of stator windings were indicated the internal discharge. PD patterns are consistent with the result of measurement using PDD and TGA.

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Development and Evaluation of Multi-Wavelength Excitation light Source for Fluorescence Imaging to Diagnose Malignancies (악성종양의 형광영상 진단을 위한 다파장 여기광원장치의 개발과 평가)

  • Lim, Hyun-Soo
    • Journal of Biomedical Engineering Research
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    • v.30 no.2
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    • pp.113-121
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    • 2009
  • This study aims at designing and evaluating light source devices that can stably generate light with various wavelengths in order to make possible PDD using a photosensitizer and diagnosis using auto-fluorescence. The light source was a Xenon lamp and filter wheel, composed of an optical output control through Iris and filters with several wavelength bands. It also makes the inducement of auto-fluorescence possible because it is designed to generate a wavelength band of 380-420nm, 430-480nm, and 480-560nm. The transmission part of the light source was developed to enhance the efficiency of light transmission. To evaluate this light source, the characteristics of light output and wavelength band were verified. To validate the capability of this device as PDD, the detection of auto-fluorescence using mouse models was performed.

The Central Beam Characteristics of 6 MV X-Ray - The PDD and TMR for Siemens Linear Accelerator K.D. - (6MV X-선 선축중심선상에서의 BEAM 특성 - Siemens MEVATRON KD 선형가속기에서 P. D. D와 TMR을 중심으로 -)

  • Chung, Chil;Kim, Byong-Wook
    • The Journal of Korean Society for Radiation Therapy
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    • v.3 no.1
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    • pp.63-67
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    • 1989
  • The central beam characteristics of 6 MV X-ray from a Mevatron KD linear Accelerator are examin-depths The PDD (Percent Depth Dose) values and the TMR (Tissue Maximum Ratio) values are evaluated from measurement as a function of the depths and the field sizes. The calculated TMR values from the PDD are compared to those from measurement. The average differences between calculated TMR and measured one are within $1\%$ and we have concluded that calculated TMR values are acceptable for practical use.

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A Study on the economic analysis of the standing water level control system (SAL상수위 제어시스템의 경제성 분석에 관한 연구)

  • Hong, Jong-In;Hong, Seong-Wook;Kim, Sang-Won;Yang, Jin-Kook
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.05a
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    • pp.281-283
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    • 2013
  • In this paper, standing water level control system and a comparison of existing methods (anchor, PDD, DM) and economic analysis was conducted. 1) Cost PDD method (6%), DM system (4%), and the SAL standing water level control system (4%), except for the anchor system is similar to the construction of three methods based on the portion of the anchor system was analyzed that. 2) construction and maintenance costs compared with the sum of the partial was, anchor system (100%), PDD method (39%), DM system (37%), the SAL standing water level control system (21%), the SAL standing water level control system was identified as the lowest cost method of.

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Analysis of Partial Discharge in High Voltage Motor Model Coils (고압전동기 모델 코일의 부분방전 분석)

  • Kim, Hee-Dong;Kong, Tae-Sik
    • Proceedings of the KIEE Conference
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    • 2005.07c
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    • pp.2091-2093
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    • 2005
  • Five model coils of 6.6kV motor were manufactured with several defects. These stator coils have artificial defects such as void of groundwall insulation, removal of semi-conductive coating and damage of strand insulation. Epoxy-mica coupler(80 pF) was connected to five model coil terminals, respectively The voltage applied to the coils was 3.81kV, 4.76kV, 6.0kV and 6.6kV. Partial discharge(PD) tests performed in the laboratory and shield room. Digital PD detector (PDD) and turbine generator analyzer(TGA) were used to measure PD activity. TGA summarizes each plot with two quantities such as the normalized quantity number(NQN) and the peak PD magnitude(Qm). The PD levels in pC were measured with PDD. PD patterns of model coils were indicated the internal and slot discharges. PD patterns coincide with both PDD and TGA.

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The Features of Eating Habit in Pervasive Development Disorder Children (전반적 발달장애 아동의 식습관 양상)

  • 박금순;정철호
    • Korean journal of food and cookery science
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    • v.10 no.1
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    • pp.13-17
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    • 1994
  • The purpose of this study was to show the abnormal eating habit in pervasive development disorder (PDD) children. The authors studied retrospectively the features of eating habit in 60 PDD children diagnosed by DSM-III-R who made their first visity to Department of Psychiatry, Dongsan Medical Center Keimyung University, from January 1990 to December 1990. The results were as follows;1. The average was 3 years, onset age of illness was before 3 years of all patients, and the ratio between male and female was 5,7:1, and ratio between autistic disorder and PDDNOS was 4:1. 2. Twenty four of 60 PDD children had one or more abnormal eating habit(autistic disorder; 43.8%, PDDNOS; 25%), and more prevalent to male(43.1%,) than female(22.2%). 3. Milk, biscuit, meat and fluids were the favorate foods, the unfavorate foods were vegetable, rice, frutis. 4. Patients of abnormal eating habit were more symptoms of DSM-III-R on 'lack of awareness', 'preoccupation with parts of objects','distress over change'and 'insistence on routine' than others.

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Evaluation of Detector Dependency on Collimator in SRS: Compared Detectors; CC01, CC13, SFD (뇌정위적 방사선수술 시 콜리메이터 크기 변화에 따른 검출기 의존성 평가)

  • Bae, Yong-Ki;Bang, Dong-Wan;Park, Byung-Moon;Kang, Min-Yeong;Kim, Yeon-Rye
    • The Journal of Korean Society for Radiation Therapy
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    • v.20 no.2
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    • pp.109-113
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    • 2008
  • Purpose: To evaluate the detector dependency in the various collimator size for Stereotactic Radiosugery (SRS). Materials and Methods: This study was performed with 6 MV photon beam (Varian 21EX, Varian, US) and the measurement detectors are used by ion chamber CC01, CC13 (Wellhofer, Germany) and stereotactic diode detector (SFD, Wellhofer, Germany). SRS collimator size was used by ${\varphi}$5, 10, 20, 30 mm (Brain Lab, Germany). Percentage depth dose (PDD) was measured at SSD 100 cm and field size 10×10 cm from individual detectors. Ouput factor was measured by using same setup of PDD and with maximum dose depth. Data was normalized at field size $10{\times}10\;cm$. Beam profile was measured at SSD 100 cm in SRS collimator ${\varphi}$10, 30 mm and field $10{\times}10\;cm$ and a comparison of FWHM (full width half maximum), penumbra width (20~80%). Results: The CC13 detector was overestimated 16% than other detectors from the PDD in the 5 mm collimator. Output factors were underestimated CC01 28%, CC13 72% in the 5 mm collimator and CC01 9.6%, CC13 25% in the 10 mm collimator than the SFD. Maximum difference was 3% at the FWHM of the dose profile in the 10 mm collimator and difference of the 30 mm collimator was 0% at the FWHM. Penumbra width was increased CC01 122%, CC13 194% in the 10 mm collimator and CC01 68%, CC13 185% in the 30 mm collimator than the SFD. Conclusion: It is very important for accurate dosimetry to select a detector in small field. The SFD was considered with the most accurate dosimeter for small collimator dosimetry in this study.

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