• The Transactions of the Korean Institute of Electrical Engineers C
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• v.49 no.3
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• pp.186-195
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• 2000

In this paper, partial discharge (PD) measurement was performed to evaluate the quality of the cable joint and termination constructions. The resistive coupling technique for PD detection using resistivity of semiconducting layer of the cable in the accessories, such as joints and terminations. With high frequency PD (HEPD) measurement, an excellent sensitivity below 20pC could be achieved under unshielded condition. The localization of the defects in the accessories could be identified. During heating cycle, PDs were monitored and analyzed. At that time, the PDs were dependent on the temperature of the heating cycle and showed cyclic behaviors, which were attributed to local delamination of the interfaces, between epoxy unit and stress relief cone(SRC) and between SRC and cable, due to the difference of thermal expansion. As a conclusion, HFPD measurement technique was proven to be an effective diagnostic method for qualification of extra high voltage (EHV) cable accessories. With this technique, the optimal design of the components of the accessories could be verified not only in an early stage but also under operating condition. This technique would result in the improvement of the reliability of the EHV cable accessories.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.8
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• pp.1605-1614
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• 2009

The technique of simultaneous localization and mapping is the most important research topic in mobile robotics. In the process of building a map in its available memory, the robot memorizes environmental information on the plane of grid or topology. Several approaches about this technique have been presented so far, but most of them use mapping technique as either grid-based map or topology-based map. In this paper we propose a frame of solving the SLAM problem of linking map covering, map building, localizing, path finding and obstacle avoiding in an automatic way. Some algorithms integrating grid and topology map are considered and this make the SLAM performance faster and more stable. The proposed scheme uses an occupancy grid map in representing the environment and then formulate topological information in path finding by A${\ast}$ algorithm. The mapping process is shown and the shortest path is decided on grid based map. Then topological information such as direction, distance is calculated on simulator program then transmitted to robot hardware devices. The localization process and the dynamic obstacle avoidance can be accomplished by topological information on grid map. While mapping and moving, pose of the robot is adjusted for correct localization by implementing additional pixel based image layer and tracking some features. A laser range finer and electronic compass systems are implemented on the mobile robot and DC geared motor wheels are individually controlled by the adaptive PD control method. Simulations and experimental results show its performance and efficiency of the proposed scheme are increased.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.12
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• pp.1697-1703
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• 2014

In this paper, we propose an indoor RSSI (received signal strength indication)-based localization method that uses virtually overlapped visible light with an indoor LED lighting system. In our system, a photodiode (PD) measures the RSSI from LED lamps that blink in one row or column units. Subsequently, the RSSI is used to obtain the horizontal distances between the LED lamps and the receiver with the predetermined characteristics curve, R-D curve, that represents the relation between the RSSI and the horizontal distances. When the controlled LED lamps blink in one row or column units, the R-D curve at the border of the LED lamps is different because of the weak lighting, which results in the position sensing error of the receiver. The deviation of the optical power of each LED also causes the error. To solve these problems, we propose a method that overlaps the visible light through the numerical operation at the receiver side without any modification of the light source side. Our proposed method has been simulated in a room measuring $1.2{\times}1.2{\times}1.8m^3$ considering the effect of the error on the optical power of the LED. The simulation result shows that the proposed method eliminates the error condition with the R-D curve and achieves an average positioning error of 13.4 mm under the error rate 3% of the optical power.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.10
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• pp.119-130
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• 2018

In the late 1950s, departing from their unquestioning following of Soviet architecture, North Koreans attempted to discover the specificities of traditional Korean architecture and apply them to their contemporary monuments. This paper examines the ways in which North Korean architects developed their unique version of Socialist realism in the making of Pyongyang Grand Theater. The traditional elements in harmony with North Korea's political ideology-an early form of Juche ideology-and modern building technologies were to be viewed as contemporary elements, and not as a simple revival of the past. This study applies Socialist realism's compositional principle "national in form and socialist in content" to Pyongyang Grand Theater and examines specifically what "socialist content" and "national form" were and how the two were combined in the construction of Pyongyang Grand Theater. By situating the building in the context of localization of Socialist realism which is universal art principle of the communist world, this study contributes to the deeper and wider understanding of North Korea's Modern Joseon Architecture.

• BMB Reports
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• v.55 no.10
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• pp.494-499
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• 2022

PTEN-induced putative kinase 1 (PINK1) is a serine/threonine kinase that phosphorylates several substrates and exerts neuroprotective effects against stress-induced apoptotic cell death. Mutations in PINK1 have been linked to autosomal recessive forms of Parkinson's disease (PD). Mitophagy is a type of autophagy that selectively promotes mitochondrial turnover and prevents the accumulation of dysfunctional mitochondria to maintain cellular homeostasis. Toll-interacting protein (Tollip) was initially identified as a negative regulator of IL-1β receptor signaling, suppressing inflammatory TLR signaling cascades. Recently, Tollip has been reported to play a role in autophagy and is implicated in neurodegeneration. In this study, we determined whether Tollip was functionally linked to PINK1-mediated mitophagy. Our results demonstrated that Tollip promoted the mitochondrial processing of PINK1 and altered the localization of PINK1, predominantly to the cytosol. This action was attributed to increased binding of PINK1 to mitochondrial processing peptidase β (MPPβ) and the subsequent increase in MPPβ-mediated mitochondrial PINK1 cleavage. Furthermore, Tollip suppressed mitophagy following carbonyl cyanide m-chlorophenylhydrazone-induced mitochondrial dysfunction. These findings suggest that Tollip inhibits mitophagy via the PINK1/parkin pathway upon mitochondrial damage, leading to the blockade of PINK1-mediated neuroprotection.

• Proceedings of the KIEE Conference
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• 2006.05a
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• pp.74-77
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• 2006

This research is focused on the development of GIS Diagnostic SYSTEM to prevent accidents beforehand by inspecting the internal defects of GIS (Gas Insulated Switchgear) which is a main power-facility for substations. GIS Diagnostic SYSTEM is categorized as 'Real time on-line test type' and 'Portable test type' depending on the types of testing, it uses PD(partial discharge) which mostly incurs in GIS internal defects, to inspect. As of now, mostly foreign equipments are imported for use due to the lack of the technology localization, and these are installed and operated on only some parts of highly-graded GIS power-facilities such as in 76skv or 345kv for its being expensive. Furthermore, other than foreign equipments being costly, it also has a weak point of very long unavailability in case of Diagnostic system break-down while using, because it takes a comparatively long period of corrective maintenance precesses. We have localized to develop personal real-time multi -functional GIS Diagnostic system which can test on all GIS power-facility comprehensively and economically therefore overcome all these problems mentioned above, a market expansion is expected from the decrease of price and replacing the import equipments in the future. As the equipment was developed to be Personal for the simple ways of installing and utilizing, it can be operated without any complex cable installation like other existing GIS Diagnostic system requires, therefore also decrease the cost of cable installation.

• Korean Journal of Radiology
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• v.24 no.3
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• pp.247-258
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• 2023

Objective: To localize the neuroanatomical substrate of rapid eye movement sleep behavior disorder (RBD) and to investigate the neuroanatomical locational relationship between RBD and α-synucleinopathy neurodegenerative diseases. Materials and Methods: Using a systematic PubMed search, we identified 19 patients with lesions in different brain regions that caused RBD. First, lesion network mapping was applied to confirm whether the lesion locations causing RBD corresponded to a common brain network. Second, the literature-based RBD lesion network map was validated using neuroimaging findings and locations of brain pathologies at post-mortem in patients with idiopathic RBD (iRBD) who were identified by independent systematic literature search using PubMed. Finally, we assessed the locational relationship between the sites of pathological alterations at the preclinical stage in α-synucleinopathy neurodegenerative diseases and the brain network for RBD. Results: The lesion network mapping showed lesions causing RBD to be localized to a common brain network defined by connectivity to the pons (including the locus coeruleus, dorsal raphe nucleus, central superior nucleus, and ventrolateral periaqueductal gray), regardless of the lesion location. The positive regions in the pons were replicated by the neuroimaging findings in an independent group of patients with iRBD and it coincided with the reported pathological alterations at post-mortem in patients with iRBD. Furthermore, all brain pathological sites at preclinical stages (Braak stages 1-2) in Parkinson's disease (PD) and at brainstem Lewy body disease in dementia with Lewy bodies (DLB) were involved in the brain network identified for RBD. Conclusion: The brain network defined by connectivity to positive pons regions might be the regulatory network loop inducing RBD in humans. In addition, our results suggested that the underlying cause of high phenoconversion rate from iRBD to neurodegenerative α-synucleinopathy might be pathological changes in the preclinical stage of α-synucleinopathy located at the regulatory network loop of RBD.

• The Korean Journal of Nuclear Medicine
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• v.39 no.1
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• pp.9-14
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• 2005

Purpose: Abnormal myocardial perfusion may be caused by ventricular preexcitation, but its location, extent, severity and correlation with accessory pathway (AP) are not established. We evaluated perfusion patterns on myocardial perfusion SPECT and location of AP in patients with WPW (Wolff-Parkinson-White) syndrome. Materials and Methods: Adenosine Tc-99m MIBI or Tl-201 myocardial perfusion SPECT was performed in 11 patients with WPW syndrome. Perfusion defects (PD) were compared to AP location based on ECG with Fitzpatrick's algorithm or electrophysiologic study and radiofrequency catheter ablation. Results: Patients had atypical chest discomfort or no symptom. Risk of coronary artery disease (CAD) was below 0.1 in 11 patients using the nomogram to estimate the probability of CAD. Coronary angiography was performed in 4 patients (mid-LAD 50% in one, normal in others). In 4 patients, AP localization was done by electrophysiologic study and radiofrequency catheter ablation (RFCA). Small to large extent ($11.0{\pm}8.5%$, range:$3{\sim}35%$) and mild to moderate severity ($-71{\pm}42.7%$, range:$-2l7{\sim}-39%$) of reversible (n=9) or fixed (n=1) perfusion defects were noted. One patient with right free wall (right lateral) AP showed normal. PD locations were variable following the location of AP. One patient with left lateral wall AP was followed 6 weeks after RFCA and showed significantly decreased PD on SPECT with successful ablation. Conclusion: Myocardial perfusion defect showed variable extent, severity and location in patients with WPW syndrome. Abnormal perfusion defect showed in most of all patients, but it did not seem to be correlated specifically with location of accessory pathway and coronary artery disease. Therefore myocardial perfusion SPECT should be interpreted carefully in patients with WPW syndrome.

• Molecules and Cells
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• v.28 no.5
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• pp.431-439
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• 2009

Rice Oryza sativa accelerated cell death and resistance 1 (OsACDR1) encodes a putative Raf-like mitogen-activated protein kinase kinase kinase (MAPKKK). We had previously reported upregulation of the OsACDR1 transcript by a range of environmental stimuli involved in eliciting defense-related pathways. Here we apply biochemical, gain and loss-of-function approaches to characterize OsACDR1 function in rice. The OsACDR1 protein showed autophosphorylation and possessed kinase activity. Rice plants overexpressing OsACDR1 exhibited spontaneous hypersensitive response (HR)-like lesions on leaves, upregulation of defense-related marker genes and accumulation of phenolic compounds and secondary metabolites (phytoalexins). These transgenic plants also acquired enhanced resistance to a fungal pathogen (Magnaporthe grisea) and showed inhibition of appressorial penetration on the leaf surface. In contrast, loss-of-function and RNA silenced OsACDR1 rice mutant plants showed downregulation of defense-related marker genes expressions and susceptibility to M. grisea. Furthermore, transient expression of an OsACDR1:GFP fusion protein in rice protoplast and onion epidermal cells revealed its localization to the nucleus. These results indicate that OsACDR1 plays an important role in the positive regulation of disease resistance in rice.