• Tuberculosis and Respiratory Diseases
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• 제67권5호
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• pp.430-435
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• 2009

Background: Thus far, research studies on community-acquired pneumonia (CAP) have focused on its clinical severity. Recently, it has been determined that procalcitonin (PCT) level is correlated with severity of CAP. A retrospective study conducted at our hospital used risk predictability and PCT to determine whether or no PCT is useful in assessing the severity of CAP. Methods: This study covered 92 CAP cases that were admitted to the respiratory department at Changwon Fatima Hospital between July 1, 2008 and June 30, 2009. All enrolled subjects were measured for infection markers and risk predictability. Results: Based on hospital admission data, enrolled subjects had Pneumonia Severity Index (PSI) scores serving as risk predictors showed that both PCT and white blood cell (WBC) were statistically significant as infection markers (p=0.001, 0.037). Thus, this study used ROC curves in PSI for data analysis. As a result, it was determined that the area under curve (AUC) of PCT and WBC was 0.694 and 0.593 respectively, indicating that PCT has a higher test value for WBC, when PCT was higher than 0.745 ng/mL. In addition, it was found that PCT levels higher than 0.745 ng/mL had higher PSI scores than the group with PCT lower than 0.745 ng/mL (p=0.032). Conclusion: In order to predict risk of pneumonia cases admitted due to symptoms of CAP, it is important to consider PCT as well as PSI, and follow-up monitoring of PCT cases.

• 고신대학교 의과대학 학술지
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• 제33권3호
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• pp.337-346
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• 2018

Objectives: Serum procalcitonin (PCT) is a specific biomarker that rises after bacterial infection, and levels of PCT are known to correlate with the severity and mortality of patients with pneumonia and sepsis. However, the usefulness of PCT levels in acute pyelonephritis is unknown. This study aimed to evaluate the effectiveness of using the PCT level as a predictive test for bacteremia in acute pyelonephritis. Methods: Between January 2012 and June 2013, 140 patients diagnosed with acute pyelonephritis were admitted to Haeundae Paik Hospital. Serum PCT, C-reactive protein (CRP), and white blood cell (WBC) levels at pre- and post- treatment were measured. Blood and urine cultures were obtained from all patients. The levels of PCT, CRP, and WBCs were each compared between the blood culture-positive and blood culture-negative groups to assess their effectiveness in predicting bacteremia. Results: Pre-treatment PCT level was 0.77 ng/mL (95% CI: 0.42-1.60 ng/mL) in the blood culture-negative group and 4.89 ng/mL (95% CI: 2.88-9.04 ng/mL) in the blood culture-positive group, and the increase between the two groups was statistically significant. The area under the receiver operating characteristic curve of PCT level for prediction of bacteremia was 0.728. A cut-off value of 1.23 ng/mL indicated a sensitivity of 79.0 % and specificity of 60.0 % for PCT level. Conclusions: Serum PCT level is a useful predictive test for bacteremia in acute pyelonephritis. Through the early detection of bacteremia, serum PCT level can help estimate the prognosis and predict complications such as sepsis.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1998년도 춘계학술발표회논문집(2)
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• pp.391-396
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• 1998

Modified product Consistency Test (M-PCT) has been developed as an alternative to other existing methods in determining the leachability of glass. M-PCT, the leaching method, is a hybrid of MCC-l and PCT, but can provide quicker sample preparation. Larger diameter glass sample (1.0-2.0 mm) than in the PCT method can be used so that the glass beads are more easily produced and cleaned. From the M-PCT, the total mass loss (ML) of glass, the normalized elemental release rate (NLi), pH value of leachate have been obtained. For some selected glasses in which leaching rates have been known, their chemical durablility have been tested using the M-PCT method. The results are compared to the literature data for the glasses. It is found that M-PCT method is reasonable and suitable in determining the leachability of Low and Intermediate level Radioactive Waste glass form, such as the pH, elemental loss and total mass loss.

• 전자통신동향분석
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• 제12권5호통권47호
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• pp.121-130
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• 1997

본 고는 앞으로 자주 사용하게 될 PCT 국제특허 출원제도를 소개하여 이를 활성화하고자 작성하였다. 국제출원의 개요를 설명하고 PCT 출원 처리절차 특히 국제조사, 국제공개, 국제예비심사까지의 일련의 과정을 설명하여 연구원들의 이해를 높이고 장단점을 비교하여 어떻게 이 제도를 사용할 것인지를 설명하였다.

• 디지털콘텐츠
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• 11호통권66호
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• pp.74-78
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• 1998

PCT는 WIPO IPDL(WIPO Intellectual Property Digital Library) 프로젝트에 의해 만들어진 데이터베이스이며, PCT를 통해 출원된 국제특허자료를 인터넷을 통해 무료로 검색해 볼 수 있다.

• Clinical and Experimental Pediatrics
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• 제60권1호
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• pp.10-16
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• 2017

Purpose: Although procalcitonin (PCT) level is useful for the diagnosis of neonatal sepsis, PCT reliability is inconsistent because of the varied conditions encountered in neonatal intensive care units. This study aimed to investigate PCT levels and factors influencing increased PCT levelin newborns without bacterial infection during the first week of life. Methods: In newborns hospitalized between March 2013 and October 2015, PCT levels were measured on the first, third, and seventh days after birth. Newborns with proven bacterial (blood culture positive for bacteria) or suspicious infection (presence of C-reactive protein expression or leukocytosis/leukopenia) were excluded. Various neonatal conditions were analyzed to identify the factors influencing increased PCT level. Results: Among 292 newborns with a gestational age of $35.2{\pm}3.0$ weeks and a birth weight of $2,428{\pm}643g$, preterm newborns (n=212) had higher PCT levels than term newborns (n=80). Of the newborns, 7.9% had increased PCT level (23 of 292) on the firstday; 28.3% (81 of 286), on the third day; and 3.3% (7 of 121), on the seventh day after birth. The increased PCT level was significantly associated with prenatal disuse of antibiotics (P=0.004) and surfactant administration (P<0.001) on the first day after birth, postnatal use of antibiotics (P=0.001) and ventilator application (P=0.001) on the third day after birth, and very low birth weight (P=0.042) on the seventh day after birth. Conclusion: In newborns without bacterial infection, increased PCT level was significantly associated with lower gestational age and respiratory difficulty during the first week of life. Further studies are needed for clinical applications.

• 대한토목학회논문집
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• 제33권3호
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• pp.889-900
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• 2013

대형 구조물의 기초나 지중 구조물 시공을 위한 대규모 굴착 시 매우 큰 토압이 발생할 수 있다. 이러한 큰 토압을 지지하기 위해 기존에 사용되어 온 강재 버팀보를 적용할 경우 경제성 및 효율성이 저하될 우려가 있다. 이러한 점을 개선하기 위해 PCT(Precast Concrete Truss) 시스템을 고안하였으며 이에 대한 실험 및 해석적 연구를 수행하였다. 콘크리트 트러스 부재의 조립 및 해체를 용이하게 하기 위해 적절한 연결방법이 제안되었다. 이러한 연결부를 포함한 PCT 시스템의 내하력을 검증하기 위해 실대형 실험이 실시되었으며, 실험결과는 구조해석결과와도 비교되었다. PCT 버팀보를 모사한 시험체는 극한하중 도달 시까지 좌굴이 발생하지 않았으나, 연결 부재 상세에 대한 일부 개선점이 도출되었다. PCT 시스템은 대규모 굴착 시 기존의 강재 버팀보를 대체하는 가설구조물로서 효율적으로 활용될 수 있을 것으로 기대된다.

• Clinical and Experimental Pediatrics
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• 제57권10호
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• pp.451-456
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• 2014

Purpose: We evaluated serum procalcitonin (PCT) as a diagnostic marker of neonatal sepsis, and compared PCT levels with C-reactive protein (CRP) levels. Methods: We retrospectively reviewed the medical records of 269 neonates with a suspected infection, admitted to Wonkwang University School of Medicine & Hospital between January 2011 and December 2012, for whom PCT and CRP values had been obtained. Neonates were categorized into 4 groups according to infection severity. CRP and PCT values were analyzed and compared, and their effectiveness as diagnostic markers was determined by using receiver operating characteristic (ROC) curve analysis. We also calculated the sensitivity, specificity, and positive, and negative predictive values. Results: The mean PCT and CRP concentrations were respectively $56.27{\pm}81.89$ and $71.14{\pm}37.17mg/L$ in the "confirmed sepsis" group; $15.64{\pm}32.64$ and $39.23{\pm}41.41mg/L$ in the "suspected sepsis" group; $9.49{\pm}4.30$ and $0.97{\pm}1.16mg/L$ in the "mild infection" group; and $0.21{\pm}0.12$ and $0.72{\pm}0.7mg/L$ in the control group. High concentrations indicated greater severity of infection (P<0.001). Five of 18 patients with confirmed sepsis had low PCT levels (<1.0 mg/L) despite high CRP levels. In the ROC analysis, the area under the curve was 0.951 for CRP and 0.803 for PCT. The cutoff concentrations of 0.5 mg/L for PCT and 1.0 mg/L for CRP were optimal for diagnosing neonatal sepsis (sensitivity, 88.29% vs. 100%; specificity, 58.17% vs. 85.66%; positive predictive value, 13.2% vs. 33.3%; negative predictive value, 98.6% vs. 100%, respectively). Conclusion: PCT is a highly effective early diagnostic marker of neonatal infection. However, it may not be as reliable as CRP.

• Journal of Dental Anesthesia and Pain Medicine
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• 제15권3호
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• pp.135-140
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• 2015

Background: Identifying early markers of septic complications can aid in the diagnosis and therapeutic management of hospitalized patients. In this study, the utility of procalcitonin (PCT) vs. C-reactive protein (CRP) as early markers of sepsis was compared. Methods: A series of 2,697 consecutive blood samples was collected from hospitalized patients and serum PCT and CRP levels were measured. Patients were categorized by PCT level as follows: < 0.05 ng/ml, 0.05-0.49 ng/ml, 0.5-1.99 ng/ml, 2-9.99 ng/ml, and > 10 ng/ml. Diagnostic utility was analyzed by receiver operating characteristic (ROC) curves. Results: Mean CRP levels varied among the five PCT categories at $0.31{\pm}2.87$, $5.65{\pm}6.26$, $13.78{\pm}8.01$, $12.15{\pm}10.16$, and $17.77{\pm}10.59$, respectively (P < 0.05). PCT and CRP differed between positive and negative blood culture groups (PCT: 15.9 vs. 4.78 mg/dl;CRP: 11.5 ng/ml vs. 9.57 ng/ml;P < 0.05). The areas under the ROC curves (PCT, 95% confidence interval [CI]: 0.743, range: 0.698-0.789 at a threshold of 0.5 ng/ml; CRP, 95% CI: 0.540, range: 0.478-0.602 at a threshold of 8 mg/l) differed for PCT and CRP (P < 0.05). Conclusions: Therefore, PCT is a reliable marker for sepsis diagnosis and is more relevant than CRP in patients with a positive blood culture. These findings can be useful for the treatment of critically ill sepsis patients.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.41-44
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• 2008

PCT는 장경간 가시설 벽체를 지지하는 써포트 구조물을 프리캐스트 방식으로 공장에서 미리 제작하고, 콘크리트 소재로 구성하여 강성을 만족시킬 수 있도록 그 구조가 개선된 프리캐스트 가시설 구조체이다. 그것의 부재들은 공장에서 미리 정형화된 형태로 제작되고 가시설 벽체의 내측면에 고정수단을 매개로 근접되게 배치된다. PCT system은 내부에 콘크리트가 충진되는 세그먼트 부재들의 단부와 접촉되어 결합수단을 매개로 일체화되어 또한 다른 세그먼트 부재를 연결시키는 연결구로 이루어진 써포트 구조물로 구성된 것이다. 본 연구는 전체적인 길이가 긴 장경간 가시설 벽체에 대한 충분한 지지력을 얻을 수 있을 뿐만 아니라, 프리캐스트 방식으로 제작되어 콘크리트 양생에 소요되는 시간을 단축시킬 수 있으므로 시공기간이 단축되는 등의 유용한 효과를 갖는다.