• Title/Summary/Keyword: PC-NC

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Modification of Gut Microbiota and Immune Responses via Dietary Protease in Soybean Meal-Based Protein Diets

  • Song, Minho;Kim, Byeonghyeon;Cho, Jin Ho;Kyoung, Hyunjin;Choe, Jeehwan;Cho, Jee-Yeon;Kim, Younghoon;Kim, Hyeun Bum;Lee, Jeong Jae
    • Journal of Microbiology and Biotechnology
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    • v.32 no.7
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    • pp.885-891
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    • 2022
  • Plant-based protein sources such as soybean meal have low digestibility and are generally promoted accumulation of undigested proteins into the intestine by enzymatic treatments. Moreover, potential intestinal pathogens ferment undigested proteins, producing harmful substances, such as ammonia, amines and phenols, leading to an overactive immune response and diarrhea in weaned pigs. As a solution, dietary proteases hydrolyze soybean-based antinutritive factors, which negatively affect immune responses and gut microbiota. In this study, we investigated the effects of dietary proteases (PRO) in a low-crude protein (CP) commercial diet on the immune responses and gut microbiota of weaned pigs. The experimental design consisted of three dietary treatments: a commercial diet as a positive control (PC; phase1 CP = 23.71%; phase 2 CP: 22.36%), a lower CP diet than PC as negative control (NC; 0.61% less CP than PC), and NC diet supplement with 0.02% PRO. We found that PRO tended to decrease the frequency of diarrhea in the first two weeks after weaning compared with PC and NC. In addition, pigs fed PRO showed decreased TNF-α and TGF-β1 levels compared with those fed PC and NC. The PRO group had a higher relative proportion of the genus Lactobacillus and lower levels of the genus Streptococcus than the PC and NC groups. In conclusion, the addition of PRO to a low CP commercial weaned diet attenuated inflammatory responses and modified gut microbiota in weaned pigs.

Development of Software Interpolators for PC-based NC Machine Tools (PC-based NC 공작기계의 소프트웨어 보간기 개발)

  • Yang, Min-Yang;Hong, Won-Pyo
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.12
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    • pp.99-105
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    • 1996
  • Increasing demands on precision machining of free-form surfaces have necessitated the tool to move not only with position error as small as possible, but also with smoothly varying feedrates. In this paper, linear, circular and spline interpolators were developed in reference-pulse type using PC. M-SAM and M-DAM were designed by the comparison and analysis of previous interpolation methods. Spline interpolator was designed to follow the free-form curves. To apply to the real cutting process, constant feedrate compensation and acceleration-deceleration compensation were conceived. Finally, its performance was tested using retrofitted milling machine. As a result, new interpolation algorithm is favorable in precision machining of free-form curves.

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Synthesis and Characterization of Palladium and Platinum Complexes of N,N'-Bis[2'-(diphenylphosphino)phenyl]propane-1,3-diamine. Single-Crystal Structures of $[Pd(Ph_2PC_6H_4NC_3H_6NC_6H_4PPh_2)]$ and $[Pt(Ph_2PC_6H_4NH)(SEt_2)Cl]$

  • 유동원;김은진;강상옥;고재정;이승희
    • Bulletin of the Korean Chemical Society
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    • v.19 no.5
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    • pp.565-568
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    • 1998
  • Novel mononuclear metal complexes with the formula $[M(Ph_2PC_6H_4NC_3H_6NC_6H_4PPh_2)]$ (M=Pd (1); M=Pt (2)) were obtained when N,N'-bis[2'-(diphenylphosphino)phenyl]propane-1,3-diamine, I was mixed with cisdichlorobis(diethylsulfide)palladium and platinum in the presence of NEt3. Two mononuclear metal compounds with the fomula [M(Ph2PC6H4NH)(SEt2)Cl] (M=Pd (3); M=Pt (4)) were synthesized from $M(SEt_2)2Cl_2$ and N-(2'-diphenylphosphinophenyl)-4-amino-1,1,1,5,5, 5-hexafluoro-3-penten-2-one, II by the elimination reaction of hexafluoro pentenone. The X-ray single crystal structures of 1 and 4 are described. X-ray single crystal diffraction analyses reveal that compound 1 is a mononuclear palladium compound with P,N,N,P-coordination mode and 4 is a mononuclear platinum compound with P,N-coordination mode.

A study on CAM System for Machining of Sculptured Surface in Mold Cavity(2) -Machining Algorithm and Construction of the System- (3차원 자유곡면 가공용 CAM시스템의 개발에 관한 연구 (2) -가공 알고리즘 및 시스템 구성-)

  • 정희원;정재현
    • Journal of Advanced Marine Engineering and Technology
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    • v.19 no.1
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    • pp.54-59
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    • 1995
  • In this paper, we propose unique CAM system for personal computer that can define the geometric shape in an ease manner and to machine the sculptured surfaces of a mold cavity. In this CAM system, if a user inputs simple initial information such as the control points for a shape definition and a radius of tool etc., all of the procedures for machining will be processed automatically by the CAM system as well as NC commands and simulations. In addition to this, the environment of the CAM system is composed of "C" language for an easy extention of aditional modules. Also, the CAM system with the following characteristics was developed. 1. The optimum tool path satisfying given tolerance limits reduces the time for the high precision machining of sculptured surface in a mold cavity. 2. The generated NC commands can be transmitted to NC directly by the CAM system through RS-232C from PC.C from PC.

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The Development of Grinding Robot System Using NC data and Off-line Programming (수치제어 데이터와 오프라인 프로그램을 이용한 연마 로봇 시스템 개발)

  • Oh, Young-Sup;Ryuh, Beom-Sahng
    • Journal of the Korean Society for Precision Engineering
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    • v.16 no.3 s.96
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    • pp.9-17
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    • 1999
  • This paper presents a method of grinding and polishing automation of precision die after CNC machining. The method employs a robot system equipped with a pneumatic spindle and a special abrasive film pad. The robot program is automatically generated off-line program form a PC and downloaded to robot controller. Position and orientation data for the program is supplied form cutter contact (CC) data of NC machining process. This eliminates separate robot teaching process. This paper aims at practical automation of die finishing process which is very time consuming and suffering from shortage of workpeople. Time loss due to changeover from one product to another is eliminated by PC off-line programming exploiting appropriate NC machining data. Dextrous 6-axis robot with rigid wrist and simple tooling enables the process applicable to larger, rather complex 3 dimensional free surfaces.

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Evaluation of the Effect of Low Dietary Fermentable Carbohydrate Content on Growth Performance, Nutrient Digestibility, Blood Characteristics, and Meat Quality in Finishing Pigs

  • Hong, S.M.;Hwang, J.H.;Kim, In-Ho
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.9
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    • pp.1294-1299
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    • 2012
  • A total of 96 pigs ($49.23{\pm}3.20$ kg) were used in an 11 wk growth trial to evaluate the effect of fermentable carbohydrate (FC) content on growth performance, apparent total tract digestibility (ATTD) of nutrient, blood profile, and meat quality. The dietary treatments were: i) negative control (NC), basal diet, ii) positive control (PC), NC+antibiotics (positive control diet with 5 ppm flavomycin), iii) PCL, PC-13% lower FC, and iv) NCL, NC-13% lower FC. The growth performance (average daily gain, average daily feed intake, and gain/feed) didn't differ among treatments through the whole experiment. These pigs fed the PCL diet had the greater (p<0.05) apparent total tract digestibility (ATTD) of dry matter than those from PC and NC treatment at the end of the experiment. No differences were observed in white blood cell (WBC), red blood cell (RBC), and lymphocyte concentration among different treatments. After the feeding period, meat samples were collected from the pigs at slaughter. The pigs in NCL and PCL treatments had greater (p<0.05) backfat thickness and lower lean percentage. The color value of loin was higher (p<0.05) in NCL treatment compared to PCL treatment. Also, the NCL treatment had higher (p<0.05) marbling value than PC treatment. The drip loss was depressed by PCL and NCL treatment comapared to NC treatments. The water holding capacity (WHC) was higher (p<0.05) in NC and PCL treatment. In conclusion, the low FC can improve digestibility and meat quality of finishing pigs.

Influences of Plant Extract Supplementation on Performance and Blood Characteristics in Weaned Pigs

  • Hong, J.W.;Kim, I.H.;Kwon, O.S.;Min, B.J.;Lee, W.B.;Shon, K.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.3
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    • pp.374-378
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    • 2004
  • One hundred and twenty crossbred pigs [(Duroc$\times$Yorkshire)$\times$Landrace] were used to determine the effects of plant extract (PE) supplementation on performance and blood characteristics in weaned pigs fed a corn-dried whey-SBM based diet. Treatments were 1) NC (antibiotic free basal diet), 2) PC (NC diet+100 ppm apramycin and 100 ppm oxytetracycline), 3) PE 0.1 (NC diet+0.1% plant extract), 4) PE 0.2 (NC diet+0.2% plant extract) and 5) PE+AB (PC diet+0.1% plant extract). Through the entire experimental period, ADG of pigs fed PC (300 vs. 281 g/d), PE 0.2 (310 vs. 281 g/d) and PE+AB (306 vs. 281 g/d) diets was higher than that of pigs fed NC diet (p<0.05). However, no differences were found among the treatments for ADFI and gain/feed. At day 2 after the onset of the experiment, fecal consistency score of pigs fed PC, PE 0.1, PE 0.2 and PE+AB diets was lower than that of pigs fed NC diet. There were no significant differences in red blood cell, white blood cell, lymphocytes, neutrophils and monocytes concentrations of blood among the treatments. In conclusion, PE can be used to replace antibiotics in diets for weaned pigs without negative affects on performance. Optimal PE levels seemed to be 0.2% and the results obtained point out to a synergic effect of the combination of PE and antibiotic on performance in weaned pigs.

Design of a graphical operating system for the NC controller (NC용 graphical OS 설계)

  • 최성락;정광조
    • 제어로봇시스템학회:학술대회논문집
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    • 1992.10a
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    • pp.519-524
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    • 1992
  • In this paper, an operating system is designed for NC controllers. Host computer is the IBM-PC, and the controller panel is designed in graphics mode to look easily for users. Pull-down menu is selected, which is useful to minimize a mistake made by users, so users can use NC controller more effectively. Also, many functions are proposed, such as NC editor for programming the NC program directly, simulation function for testing editted NC program, and new key-pad that appropriates for the functions of OS.

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Acupuncture on PC6 in Anesthesia also Shows Effect for Preventing Post Operative Nausea and Vomiting (마취 중 내관 침 시술이 수술 후 오심구토 예방에 미치는 효과)

  • Choi, Deok-Hwa;Lee, Su-Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.6
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    • pp.1085-1088
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    • 2011
  • This study aims to investigate the effect of acupuncture on PC6 for preventing opioid-induced nausea and vomiting under circumstance whether the participants are conscious or non-conscious. 143 patients receiving intravenous patient controlled analgesia(PCA) with fentanyl were assigned to three groups. Two groups were given acupuncture on PC6 before anesthesia(PreAN) or after anesthesia(PoAN) respectively. One group was control group without acupuncture treatment(NC). Assessment of nausea and vomiting was obtained from all patients for 48hours after surgery. The incidence of nausea and vomiting was significantly lower in the PreAN group and PoAN group than in the NC group. The severity of nausea was the lowest in PreAN group, second to in PoAN group, and the highest in NC group. This results show that acupuncture on PC6 even without patients' consciousness has effect on preventing PONV.

A study of On-Machine Measurement for PC-NC system

  • Yoon, Gil-Sang;Kim, Gun-Hee;Cho, Myeong-Woo;Seo, Tae-Il
    • International Journal of Precision Engineering and Manufacturing
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    • v.5 no.1
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    • pp.60-68
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    • 2004
  • The purpose of this paper is to establish an effective inspection system by using OMM (On-Machine Measurement) system based PC-NC. This system can reduce manufacturing lead time because a workpiece is inspected at every machining process and the manufacturing system which includes inspection faculty is able to realize on-line process on CNC machining center. The proposed OMM system is composed of a few algorithms for determination of inspection parameters. It is accomplished by determining the number of measuring points, their location, measuring path using fuzzy logic, Hammersley's method, TSP (Traveling Salesperson Problem) algorithm. The inspection feature applied to this system is based on machining feature. This method is tested by simulation and experiment that are analyzed measuring data and geometry tolerance.