• 제목/요약/키워드: PC-12

검색결과 1,770건 처리시간 0.024초

암환자가 지각한 사회적지지, 희망과 삶의 질과의 관계 (The Relationship among Percieved Social Support, Hope and Quality of Life of Cancer Patients)

  • 태영숙;강은실;이명화;박금자
    • 재활간호학회지
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    • 제4권2호
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    • pp.219-231
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    • 2001
  • The purpose of this study was to investigate the relationship among percieved social support, hope and quality of life of the cancer patients and to gain the baseline data for development of nursing intervention program for promoting quality of life in cancer patients. The design of this study was a cross sectional correlational survey. The subjects were 220 out and in-cancer patients in 5 general hospitals in Pusan. The data were collected from July 2 to August 1, 2001. The instruments were the Percieved social support scale(16 items, 5 point scale) had developed by Tae(1986), Hope scale(12 items, 4point scale) developed by Nowotny(1989) and Quality of life scale(31 items, 10 point scale) developed by Tae et al.(2000). The data was analyzed by the SPSS/PC+ program using frequency & percentage, item mean & standard deviation, t-test, ANOVA & Scheffe test, Pearson's correlation coefficient. The results of this study was as follows: 1) The item mean score of quality of life was $6.05{\pm}1.16$ (range 0-10). The highest score of subarea of the quality of life was the spiritual wellbeing area ($7.09{\pm}1.63$) and the lowest score was social wellbeing area ($5.53{\pm}1.65$). The mean score of perceived social support was $52.65{\pm}10.32$ (최저 1, 최고 80). The mean score of family support was $32.71{\pm}6.66$ (range 1-40) and the mean score of medical team support was $19.93{\pm}5.95$ (range 1-40). The mean score of Hope was $37.02{\pm}5.64$ (range 1-48). 2) There were statistically significant difference in the score of quality of life according to the life effect of religion(F=3.97, p=0.00), treatment method(F=2.94, p=0.01), area of diagnosis(F= 3.48, p=0.01), stage of disease (F=13.74, p=0.00). 3) There was significant correlation between perceived social support(r=0.44, p=0.000 ; family support ; r=0.334, p=0.000, medical support; r=0.395, p=0.000), hope(r=0.563, p=0.000) and quality of life. In conclusion, there was a significant relationship among perceived social support, hope and quality of life. Therefore perceived social support, hope intervention programs should be developed to improve the quality of life in cancer patients.

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수박 열수 추출물의 Tyrosinase 저해능과 신경세포 보호효과 (Tyrosinase Inhibitory Activity and Neuronal Cell Protection of Hydrothermal Extracts from Watermelons)

  • 허다정;김수정;최애란;박해룡;이승철
    • 한국식품영양과학회지
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    • 제42권10호
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    • pp.1707-1711
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    • 2013
  • 수박을 과육, 외피, 내피로 나누어 $100{\sim}300^{\circ}C$에서 10, 30, 60분간 열수 추출하여 tyrosinase 저해활성과 신경세포 보호효과를 조사하였다. Tyrosinase 저해활성은 온도가 높을수록 시간이 증가할수록 높아졌으며, 과육과 외피에서 $300^{\circ}C$, 60분 처리했을 때, 약 93%로 가장 높은 저해활성을 보였다. $300^{\circ}C$에서 60분간 열수 추출한 수박 추출물을 PC12 세포주에 농도별로(10, 50, 100, 500 ${\mu}g/mL$) 처리하여 신경세포 보호효과를 확인하였다. 열수 추출을 하지 않은 수박 부위별 추출물은 $H_2O_2$ 처리군과 세포생존율의 유의적 차이가 없었으며 이를 통해 신경세포 보호효과가 없음을 확인하였으나, 열수 추출물들은 $H_2O_2$ 단독 처리군에 비해 세포생존율이 증가하였다. 이상의 결과들은 열수 처리가 수박에 함유된 유용 물질들의 추출에 매우 유용한 공정임을 시사한다.

류마티스성 관절염 환자의 적응에 미치는 근이완술에 효과 (The Effects of Muscle Relaxation to The Rheumatoid Arthritis Patients' Adaptation)

  • 정향미
    • 근관절건강학회지
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    • 제1권1호
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    • pp.31-47
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    • 1994
  • The purposes of this research are to examine the effects of muscle relaxation to the rheumatoid arthritis patients' physiological, psychological, and social adaptation, and to verify that the technique Is an effective tool for improving the patients' adaptation. This research utilized a qusi-experimental design that compares the pre-experiment measures and the post-experiment measures. The subjects of this study were 37 out-patients who were diagnosed for rheumatoid arthritis in P university hospital and K clinic between September 12, 1993 and November 30, 1993. The experimental group consisted of patients treated on Monday, Wednesday and Friday. The control group consisted of patients treated on Tuesday, Thursday and Saturday The pre-experimental survey utilized the following tools. The physiological adaptation was measured by a graphic rating scale for pain and activity of daily living. The psychological adaptation was measured by Zung's depression scale and Rosenberg's self-esteem scale : and the social adaptation was measured by Derogatis' psychosocial adjustment scale. The experimental group received muscle relaxation treatment for 15 minutes per day for the period of 2 weeks, the control group received no treatment and had quiet time. The post-experiment measurement was carried out similar to the pre-experiment survey, SPSS $PC^+$ is used to analyze the collected data. The reliabilities of the measurement tools were examined by Cronbach's ${\alpha}$ coefficients. The homogeneities between the experimental and control groups were tested by t-test and chi-square test, hypotheses were tested by t-test. This research found that the general characteristics between the groups were statistically homogenious. The physiological, psychological, and social adaptation between the groups in the pre-experimental survey were also statistically homogenious. The results of this research can be summarized as follows : 1. Concerning the Physiological adaptation, the experimental group showed a statistically lower pain score than the control group. Thus, muscle relaxation was effective to relieve the pain of rheumatoid arthritis patients (t=-2.95, p=.006). 2. Concerning the psychological adaptation, the experimental group showed a statistically lower depression score than the control group. Thus, muscle relaxation was effective to reduce the patient's depression(t=-4.00, p=.001). 3. Concerning social adaptation, the experimental group showed a statistically higher score for the health maintenance and disease control than the control groups. Thus, muscle relaxation was effective for the health maintenance and disease control (t=2.09, p=.004). This research showed that the muscle relaxation is a nursing intervention that can promote the physiological, psychological and social adaptation of the rheumatoid arthritis patients in terms of short-term and cognitive changes. However, more fundomental changes in behavior and long-term physiology could not be found through such a short-term relaxation treatment.

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산화적 스트레스와 관련하여 신경세포의 활성에 미치는 강황 열수추출물의 영향에 대한 연구 (Effect of Curcuma longa Hot Water Extract on Activity of Neuronal Cells Related to Oxidative Stress)

  • 채용병;정경태;김성구;유병홍;김문무
    • 생명과학회지
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    • 제22권5호
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    • pp.657-664
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    • 2012
  • 본 연구의 목적은 인지기능을 가진 약효제를 발굴하는 것이다. 본 연구에서는 토끼의 간과 신경세포로부터 각각 유래한 angiotension converting enzyme과 acetylcholinesterase에 대한 강황 열수추출물(CLWE)의 억제효과 뿐만 아니라 항산화 효과가 조사되었다. 이리하여 먼저 산화적 스트레스와 연관이 있는 환원력과 DPPH radical, superoxide anion, hydroxyl radical, lipid peroxidation에 대한 CLEW의 소거능 및 DNA 산화에 대한 보호효과를 평가하였다. CLEW는 환원력 뿐만 아니라 본 연구에서 시험된 활성산소종 중에서 특히 superoxide anion의 소거능이 가장 우수한 것으로 나타났다. 더욱이 CLEW는 0.25% 이상의 농도에서 angiotensin converting enzyme 활성을 억제효과를 발휘하는 것으로 나타났다. 신경세포에서 CLEW는 또한 산화적 스트레스와 nitric oxide 유발을 억제하였다. 그러므로 이상의 결과는 CLEW의 항산화 효과와 신경세포 보호효과를 입증하여, 이것이 사람의 신경건강을 위한 천연생물소재로 잠재적인 가능성을 가지고 있을 것으로 시사한다.

치위생과 학생의 구강건강 지식과 행동변화 (Behavioral changes of dental hygiene course students according to oral health knowledge)

  • 이은경;남용옥;김설악;김민지;한동헌;김진범
    • 한국치위생학회지
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    • 제9권4호
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    • pp.715-725
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    • 2009
  • Objectives : The purpose of this study was to analyze the influence which the professional dental hygiene education has on the knowledge and behavioral change for oral health to the students in the departments of dental hygiene. Methods : 771 students in the first grade and 646 students in the third grade who were attending the departments of dental hygiene from 12 colleges in Korea were surveyed. The self-administered questionnaires were distributed to the students in the colleges during May and asked them to answer the questions and then recovered them on the spot. The collected questionnaires were analyzed by using a SPSS/PC program and the difference of significance depending on the group of the students was tested by Chi-square test or Fisher's exact probability test. Results : In the number of eating snacks by the students during one day, 2-3 times was the highest, irrespectively of the grade. The rate of the students brushing their teeth after snack was higher in the third-grade students(34.8%) than in the first-grade students(20.8%). As the path of acquiring oral health knowledge, all of the first-grade and third-grade students replied that their school classes had impacted them the most. The rate of toothache experience was a higher tendency in third-grade students compared to the first-grade students(p=0.116). The rate of gingival bleeding experience was lower in the third-grade students than in the first-grade students. The rate of oral prophylaxis experience was higher in the third-grade students than in the first-grade students. In the smoking rate, there was lower in the third-grade students than in the first-grade students. The rate of acknowledging smoking hazard to the periodontal health was higher in the third-grade students than in the first-grade students. Conclusions : This study revealed that the third-grade students of dental hygiene departments who were majoring in dental hygiene had a higher perception of oral health than the first-grade students whose the dental hygiene education period was short.

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뇌성마비 아동의 신체 기능수준과 재활 목적 치료 강도가 신체 기능향상에 미치는 영향: 6개월간 추적연구 (The Effects of Physical Function Level and Intensity of Treatment for Rehabilitation on Improvement of Physical Function in Children with Cerebral Palsy: Follow-up Study for 6 Months)

  • 김부영;윤영주;신용범;김수연;오태영
    • 대한물리의학회지
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    • 제13권1호
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    • pp.27-38
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    • 2018
  • PURPOSE: The purpose of this study was to find out the treatment patterns of Children with cerebral palsy, and to analyze the effect of physical function level and treatment intensity on improvement of physical function in children with cerebral palsy for six months. METHODS: Participants were 126 children (boys 83, girls 43) diagnosed cerebral palsy that the mean age was at 33months, ranged from 8 months to 77 months. We collected data related on demography and disable characteristic, treatment pattern using by questionnaire constructed ourselves for six months on caregivers. The treatment pattern includes, type, frequency, and institute of treatment. We performed the evaluation of Gross Motor Function Measurement (GMFM) and Pediatric Evaluation of Disability Inventory (PEDI) between pre and post for six months in order to find out improvement of physical function. We analyzed the effect of physical functional level measured by Gross Motor Functional Classification system, age, treatment intensity on physical function using by repeated measures ANOVA for SPSS PC ver. 22.0. RESULTS: The average of treatment frequency for physical therapy was 5.74 times per week, occupational therapy was 3.96 times, speech therapy was 2.96 times, treatment for accompanying disability was 3.12 times. Physical function level and age was significantly factors affecting improvement of physical function, there was no significant difference according to treatment intensity. CONCLUSION: We suggest that physical function and age might be important factors on improvement of physical function and professional rehabilitation team must consider the appropriate treatment type customized to each children.

담배 연기발생과 Tipping 재료와의 상관성 연구 (The Relationship Between Smoke-Yields and Tipping Materials of the Cigarette)

  • Kim, Young-Hoh;Lee, Young-Taek;Kim, Sung-Han;Kim, Chung-Ryul;Kim, Jong-Yeol;Shin, Chang-Ho;Lee, Keun-Hoi
    • 한국연초학회지
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    • 제20권1호
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    • pp.131-138
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    • 1998
  • In order to minimize the trial frequency in the new filter cigarette design, we studied the relationship between smoke yield and tipping materials of cigarette. A three levels full factorial design involving filament denier (X1,2.5-3.3d), Porosity of the acetate filter plug wrap (X2, 3,500-16,000CU) and porosity of the tip paper (X3, 400-1,200CU) was used. Three independent factors (Xl, X2, X3) were chosen for their effects on the various responses and the function was expressed in terms of a quadratic polynomial equation, Y : $\beta$o + $\beta$1Xl + $\beta$2X2 + $\beta$3X3 + $\beta$11Xl2 + $\beta$22X22+ $\beta$33X32 + $\beta$12X1X2 + $\beta$13XIX3 $\beta$23X2X3 which measures the linear, quadratic, and interaction effects. Twenty-nine trial numbers were obtained as a results of using a three levels full factorial design and it was analyzed by the multiple regression analysis with backward stepwise in STATISTICA/pc under restricted conditions. Tar yields of the cigarette was affected by porosity of tip paper (0.66), filament denier (0.47) and porosity of plug wrap (0.28) in the decreasing order, and linear effect of tip paper porosity (B3) and filament denier (91) were significant at a level of 0.01($\alpha$). The filament denier and tipping paper porosity interaction F ratio among three factors had a P-value of 0,000041, indicating higher interaction between these factors. Based on the analysis of variance, the model fitted for Tar (Y1) was significant at 5% confidence level and the coefficient of determination (0.96) was the proportion of variability in the data fitted for by the model.

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일 고등학교 비만학생의 건강신념과 체중조절이행과의 관계연구 (A Study on the Relationship Between Health Beliefs and Compliance with Weight Control Behavior in Obese High School Students)

  • 이광숙
    • 한국학교보건학회지
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    • 제12권2호
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    • pp.231-242
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    • 1999
  • This study was designed to identify the relation between health beliefs and compliance with weight control behavior in obese high school students living in Chonnam province. The data were collected from May 24 to 29, 1999. The instruments used in this study were modified by the authors on the basis of the results of the study's related references. The data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's Correlation using the SAS PC+ program. The results were as follows : 1. The correlation between health concern and compliance with weight control behavior was revealed as statistically significant (r= .34, p= .005). From the correlation of variables, it is concluded that there were statistically significant relations between health concern and benefit (r= .25, p= .043), between health concern and barrier (r= .33, p= .008), between susceptibility and severity (r= .64, p= .000), between susceptibility and benefit (r= .42, p= .000), between susceptibility and barrier (r= .44, p= .003), between severity and benefit (r= .37, p= .002), between severity and barrier (r= .56, p= .000), and between benefit and barrier (r= .38, p= .002). Thus, perceived susceptibility, perceived severity, perceived benefit, and perceived barrier had an indirect influence on compliance with weight control behavior. 2. In the analysis of the relationship between general characteristics and compliance with weight control behavior and health belief variables: Sex (t=2.56, p= .010) was revealed as the influencing variable of health concern. The number of those subjects living together (F=2.88, p= .044) was revealed as the influencing variable of susceptibility. Sex (t=3.47, p= .047), income (F=1.67, p= .051) was revealed as the influencing variable of barrier. 3. In the analysis of the relationship between obese characteristics and compliance with weight control behavior and health belief variables: Perception of weight (F=9.21, p= .000), family history of obesity (t=4.89, p= 030), environment of obesity (t=14.30, p= .000) were revealed as the influencing variables of susceptibility. Perception of weight (F=4.86, p= .001), symptoms of obesity (t=4.46, p= .006), family history of obesity (t=6.59, p= .012), environment of obesity (11.30, p= .001), and reasons of weight control (F=3.07, p= .010) were revealed as the influencing variables of severity. Symptoms of obesity (F=4.15, p= .009), reasons of weight control (F=2.41, p= .046) were revealed as the influencing variables of benefit. Environments of obesity (t=4.23, p= .044) were revealed as influencing variables of barrier. These results suggest that for improvement in compliance with weight control behavior, school nurses should stimulate the students' concerns about health.

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경제적 곤란과 가족갈등이 아동의 적응에 미치는 영향: 아동의 스트레스와 스트레스 대처방식의 상호작용을 중심으로 (Effects of Economic Strain and Family Conflict on Children's Adjustment : Focused on Interaction Effects of Children's Stress and Coping Strategies)

  • 윤혜미
    • 한국사회복지학
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    • 제57권3호
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    • pp.133-164
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    • 2005
  • 본 연구는 아동이 인지한 가정의 경제적 곤란과 가족갈등 스트레스가 문제행동과 학교적응에 미치는 영향을 아동의 스트레스와 대처방식 간의 상호작용에 관심을 두고 접근하였다. 자료는 C도에 거주하는 12세-15세의 아동 1,200명에 대한 설문조사를 통해 수집, 최종적으로 1,115부를 통계분석하였다. 자료분석결과, 아동의 문제행동과 학교적응에 차이를 가져오는 일반적 특성은 아동의 성, 학년과 성적이 대표적이었고, 가족유형에 따른 차이는 없었다. 경제적 곤란과 가족갈등 스트레스는 적응에 유의한 변수로 나타났으나 성에 따라 차이가 있어 남아는 내 외현화 문제행동에 경제적 곤란과 가족갈등이 영향을 미쳤으나 여아의 내재화 문제행동에는 경제적 곤란의 영향력은 유의하지 않았다. 상호작용에서도 남아의 경우 모든 적응문제에 스트레스 변인과 대처방식의 상호작용효과가 유의하였으며, 여아의 경우에는 공격성, 비행 및 불안 우울에서만 상호작용효과가 유의하게 나타났다. 아동의 스트레스 대처방식이 부적응 예방 프로그램의 한 영역으로서 연구 개발될 필요성이 논의되었다.

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일 지역 대학생의 피로와 건강증진 생활양식과의 관계분석 (The correlation analysis between fatigue and health promoting life style among a rural college students)

  • 장희정
    • 기본간호학회지
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    • 제6권3호
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    • pp.477-492
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    • 1999
  • The disease patterns among the Korean was shifted from acute and infectious diseases to chronic diseases. According to the these disease patterns trends, people have concerned about the health promotion and health behaviors. Pender's(1996) revised health promotion model(HPM) is consist of three categories; Individual characteristics and experiences, Behavior-specific cognitions and affect, behavioral outcome. Of these categories, individual characteristics and experiences, this category of variables is considered to be of biological, psychological and socio-cultural personal factors, especially, individual fatigue. Futhermore. these variables constitute a critical core for nursing intervention, as they are subject to modification through nursing actions. But there is no few the research of the relationship between the fatigue and health promotion. Therefore, the purpose of this study is to investigate the correlation between the fatigue and health promoting life style among a rural college students. Additionally, this descriptive correlational study identified the relation of demographic factors and fatigue, health promoting life style. From June 20 to 26, 1998, a convenience sample of 270 college students completed the questionnaire of the fatigue and health promoting life style profile which were developed by the Yoshitake(1978) and Walker, et al.(1987), respectively. The descriptive correlational statistics, mean, t-test, ANONA, Pearson correlation coefficient were used to analyze the data gathered with SAS pc+ program. The results were as it follows: 1. The average fatigue score of the subjects was $64.93{\pm}12.89$. Fatigue scores by subcategory were physical symptoms($23.5{\pm}4.87$). psychological symptoms($22.11{\pm}4.66$) and neuro-sensory symptoms($19.32{\pm}5.14$). With the respect to the demographic characteristics of the subjects, there were statistically significant differences between the demographic factors and fatigue, especially, sex(t==3.69 p<0.01), major(t=-2.89 p<0.01). the experience of family illness(t=2.76 p<0.01). 2. The average health promoting life style item score of the subjects was $2.33{\pm}0.33$. In the subcategories, the highest degree of performance was self-actualization(2.94), following interpersonal support(2.81). stress management(2.33), exercise(2.20), nutrition(2.10), and the lowest degree was health responsibility(1.73). There were the significant differences on the learning of health education(t=2.00 p<0.01). religion(F=3.01, p<0.05), circle activity(t=2.07, p<0.05), nutrition control(t=5.25, p<0.01) of demographical factors with the health promoting life style. 3. The correlation between the fatigue and health promoting life style made statistically no significance(r=-0.09731, p>0.05). But there was negative significant relationship between health promoting life style and psychological symptom as a fatigue subcategory(r=-0.15721, p<0.05). The self-actualization showed negative significant correlation with all fatigue subcategory. The health responsibility showed significant relationship with total fatigue(r=0.13050. p<0.05). For further research, it suggests to replicate the correlational and causal study between the fatigue and the health promoting life style using the another fatigue scale which is able to measure the subjective and objective fatigue degree. And it needs to develop the nursing intervention program for maintaining and promoting the health behavior as well as for decreasing the college students's fatigue.

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