• Korean Journal of Veterinary Research
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• v.47 no.2
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• pp.175-185
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• 2007

This study was carried out to investigate the pathogenesis and pathogenicity of the porcine circovirus type 2 (PCV2) Korean isolate from weaned pigs. Twenty four weaned pigs, PCV2, porcine reproductive and respiratory syndrome virus (PRRSV) and porcine parvovirus (PPV) antibodies free, were allocated to 4 groups (n = 6). Six pigs were inoculated intranasally with PCV2 alone, 6 with PCV2 and PRRSV, 6 with the combined PCV2/PRRSV/PPV inoculum, and 6 were remained as a uninoculated negative control. Pigs were killed 3 and 6 weeks after inoculation and tissue samples examined for gross and microscopic lesions and for the presence of PCV2 antigens and nucleic acids. Experimentally inoculated pigs were evaluated for 3 considerations: 1. development of postweaning multisystemic wasting syndrome (PMWS), 2. distribution of viral antigens by immunohistochemistry and polymerase chain reaction (PCR), and 3. cytokine mRNA levels in lymph nodes. Pigs inoculated with PCV2/PRRSV/PPV showed typical clinical signs, gross findings, and histopathologic characteristics of PMWS. In the PCV2/PRRSV/PPV inoculated group, the PCV2 antigen was widely distributed in various parenchymal organs such as brain, spinal cord, tonsil, lymph nodes, lung, heart, liver, kidney, spleen, and peyer's patch. Lymph node mRNA expression of IL-$1{\alpha}$, IL-2R and IL-8 was determined by real-time PCR. The pigs of PCV2/PRRSV and PCV2/PRRSV/PPV inoculation group, the mRNA expression was characterized by a decrease of IL-$1{\alpha}$, IL-2R and IL-8. The decrease of cytokine mRNA represent the state of T cell immuno-suppression in pig, and nicely support the evidence for the impairment of immune system in pigs with PMWS. In conclusion, PCV2 infection and some additional infectious causes such as PRRSV and/or PPV are warranted for the presence of PMWS in weaned pigs in Korea.

• Journal of Internet Computing and Services
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• v.7 no.4
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• pp.115-122
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• 2006

The purpose of this paper is to suggest the improving plans about the system as searching an effective managing devices for NEIS with analysis of managing condition. For the plans, questionnaire was performed in the five sections to primary and secondary school teachers. Those were recognition about C/S, Introduction and conductive processing of NEIS, Satisfaction of specific task on school affairs and educational matters, its function, efficiency and security as well as technical problem. Those were recognition about C/S, Introduction and conductive processing of NEIS, Satisfaction of specific task on school affairs and educational matters, its function, efficiency and security as well as technical problem. The results are following: First. in spite of satisfaction with function of C/S, it have been some problems such as frequent patch and down of server. Secondly, although the introduction of NEIS was done in hurry without gathering teachers' opinions and sufficient research of system, it has been expected to settle down normally with correction and security. Thirdly, positive reaction was generally showed in research on satisfaction of specific task for school affairs and educational matters. Fourthly, most of teachers have known the functions of NEIS and recognized its convenience. Although they has not thought it reduced their work, they have realized it's convenient for dealing with statistics. Lastly, they think of NEIS as the essential system for the age of information, in spite of problems such as reveal of personal data and security. Therefore, we should keep eyes to problem of an invasion of human right. In addition, study deep into NEIS should be conducted with consistent security for the system. In order to it. technical and legal system should be carried out side by side.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.4
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• pp.395-400
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• 2017

Atopic dermatitis is a chronic inflammatory skin disease caused by a variety of genetic and environmental factors, dysregulation of immunological response, as well as dysfunction of the skin barrier proteins. The purpose of this study is to develop an ELISA kit suitable for evaluating the expression of skin barrier proteins. Proteins were obtained from the skin via AriNo and D-Squame patches. The efficiency of protein collection from the skin, using the Arino patch, was shown to be more effective than using D-Squame; while the efficiency of lysis using 0.1% Triton-X100 was higher than that of other lysis solutions, including 0.1 M Tris-HCL, 0.1% Tween-20, and 5 mM KOH. Recombinant skin barrier proteins, such as filaggrin and involucrin, were produced by molecular biological methods. Monoclonal antibodies against filaggrin and involucrin were produced by immunization of mice, fusion of spleen cells and myeloma cells, as well as a selection of antibody-producing hybridoma cells. The filaggrin expression in the skin of subjects suffering from atopic dermatitis was lower than that in normal mice. Involucrin expression was not altered between normal individuals and subjects with atopic dermatitis. These findings contribute to an elucidation of the importance of the skin barrier protein expression in atopic dermatitis and the development of a diagnostic kit for atopic dermatitis.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.3
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• pp.227-239
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• 2008

Processing LiDAR (Light Detection And Ranging) data obtained from ALS (Airborne Laser Scanning) systems mainly involves organization and segmentation of the data for 3D object modeling and mapping purposes. The ALS systems are viable and becoming more mature technology in various applications. ALS technology requires complex integration of optics, opto-mechanics and electronics in the multi-sensor components, Le. data captured from GPS, INS and laser scanner. In this study, digital image processing techniques mainly were implemented to gray level coded image of the LiDAR data for building extraction and superstructures segmentation. One of the advantages to use gray level image is easy to apply various existing digital image processing algorithms. Gridding and quantization of the raw LiDAR data into limited gray level might introduce smoothing effect and loss of the detail information. However, smoothed surface data that are more suitable for surface patch segmentation and modeling could be obtained by the quantization of the height values. The building boundaries were precisely extracted by the robust edge detection operator and regularized with shape constraints. As for segmentation of the roof structures, basically region growing based and gap filling segmentation methods were implemented. The results present that various image processing methods are applicable to extract buildings and to segment surface patches of the superstructures on the roofs. Finally, conceptual methodology for extracting characteristic information to reconstruct roof shapes was proposed. Statistical and geometric properties were utilized to segment and model superstructures. The simulation results show that segmentation of the roof surface patches and modeling were possible with the proposed method.

• Journal of Chest Surgery
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• v.24 no.7
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• pp.674-684
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• 1991

The surgical treatment of tetralogy of Fallot [TOF] was initiated by Blalock and Taussig in 1945 with the establishment of the subclavian artery to pulmonary artery anastomosis. In an imaginative and daring effort, in 1954, Lillehei and collaborators [1955] using controlled cross-circulation, carried out the first intracardiac repair of TOF by closing the ventricular septal defect [VSD] and relieving the pulmonary stenosis under direct vision. Nowadays, total correction is the ideal operation for treatment of TOF and is accomplished with extracorporeal circulation. And the results of surgery for TOF have steadily improved over the years, thanks to important contributions of many surgeons. Nevertheless because of its protean physiologic and anatomic presentation, TOF continues to offer challenges to cardiologist and cardiac surgeons. Thirty two cases of TOF have undergone total corrective surgery using extracorporeal circulation in the Department of Thoracic & Cardiovascular Surgery, Pusan Paik Hospital, Inje University, from Oct. 1985 to Feb. 1990. Clinical considerations were applied to these cases and the results were obtained as follows. 1. The heart lung machine used for extracorporeal circulation was SarnsO 7000, 5-head roller pump, and the number and type of oxygenators were 10 of bubble type and 22 of membrane type. The mean bypass time was 148.9 minutes and the mean aortic cross clamp time was 123.8 minutes. The GIK [glucose-insulin-potassium] solution was used as cardioplegic solution for myocardial protection during operation. 2. 20 cases were male and 12 were female, the mean age was 8 years old and the mean body weight was 25Kg. 3. The preoperative symptoms were cyanosis [29 cases], squatting [27 cases] and etc. The mean values of preoperative Hb., Hct., and SaO2 were 16.5 gm /dl, 50.3%, and 78.5%. 4. Combined anomalies were noticed in 16 cases [50%]. Among them 10 cases were PFO and 6 cases were ASD. 5. The degree of aorta overriding were 25% in 5 cases, 25 ~ 50% in 22 cases and above 50% in 5 cases. The dPA/Ao [ratio of diameter of pulmonary artery trunk to ascending aorta] were below 25% in 5 cases, 25 ~ 50% in 10 cases, 50 ~ 70% in 6 cases and above 75% in 11 cases. 6. The types of RVOT [right ventricular outflow tract] stenosis were valvular and infundibular in 14 cases [43.6%], diffuse hypoplastic type in 12 cases [37.5%], infundibular in 5 cases, and valvular and supravalvular in 1 case. 7. One stage radical corrective surgery was applied to the all cases. In widening of the RVOT, 3 types of patches were used: MVOP [monocusp ventricular outflow patch, Polystan BioprosthesesO] in 3 cases, knitted Dacron vessel patches in 2 cases, and double layer with bovine pericardium and woven Dacron prosthesis in 26 cases. 8. Postoperative complications were occurred in 15 cases. Among them, low output syndrome were occurred in 10 cases [31.3%] and 2 of them were expired postoperatively.

• Journal of Chest Surgery
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• v.29 no.5
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• pp.564-568
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• 1996

Pseudoaneurysm of the ascending aorta following cardiac surgery is very unusual and it is poten- tially fatal. We report here a fourteen year-old female patient with pseudoaneurysm of the ascending aorta following a repair of a congenital ventricular septal defect at other hospital 50 months ago. Although she had a mild superficial wound infection postoperatively, she enjoyed uneventful. life until she visited our hospital for a generalized weakness and exertional dyspnea which developed a month ago. Chest CT and echocardiogram showed partially calcified pseudoaneurysm of the ascending aorta. Two aortic defects were located on the anterolateral ascending aortic wall wkere it was suspected as a previous sites of aortic and cardioplegic cannulation. The internal wall of the pseudoaneurysm was covered with neoendothelium and intervened by septal tissue. Two defects on he aortic wall were oval in shape and about 1.5cm in the greatest diameter The defects were trimmed to make a one large de- fect and it was reconstructed with patch designed from 22mm collagen impregnated double velour Dacron graft. The postoperative course was uneventful.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.5
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• pp.619-628
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• 2009

LiDAR has capability of rapid data acquisition and provides useful information for reconstructing surface of the Earth. However, Extracting information from LiDAR data is not easy task because LiDAR data consist of irregularly distributed point clouds of 3D coordinates and lack of semantic and visual information. This thesis proposed methods for automatic extraction of buildings and 3D detail modeling using airborne LiDAR data. As for preprocessing, noise and unnecessary data were removed by iterative surface fitting and then classification of ground and non-ground data was performed by analyzing histogram. Footprints of the buildings were extracted by tracing points on the building boundaries. The refined footprints were obtained by regularization based on the building hypothesis. The accuracy of building footprints were evaluated by comparing with 1:1,000 digital vector maps. The horizontal RMSE was 0.56m for test areas. Finally, a method of 3D modeling of roof superstructure was developed. Statistical and geometric information of the LiDAR data on building roof were analyzed to segment data and to determine roof shape. The superstructures on the roof were modeled by 3D analytical functions that were derived by least square method. The accuracy of the 3D modeling was estimated using simulation data. The RMSEs were 0.91m, 1.43m, 1.85m and 1.97m for flat, sloped, arch and dome shapes, respectively. The methods developed in study show that the automation of 3D building modeling process was effectively performed.

• Journal of Chest Surgery
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• v.41 no.2
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• pp.268-272
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• 2008

Paravalvular abscess is defined as infective necrosis of the mitral annulus and surrounding tissue that requires debridement of the necrotic tissue and patch reconstruction before valve implantation. Paravalvular abscess is associated with high operative mortality, postoperative complications, and recurrence. We report here a case of a 59-year old woman that had undergone mitral valvular replacement with a mechanical valve 13 years ago. The patient was determined to have paravalvular leakage due to paravalvular abscess as seen during follow-up. The patient underwent repeat mitral valvular replacement with annular reconstruction. However, the patient with mitral annular reconstruction and valvular replacement on the fifteenth postoperative day due to recurrence of paravalvular leakage. The patient is now receiving follow-up eight months after surgery.

• Economic and Environmental Geology
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• v.49 no.4
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• pp.315-323
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• 2016

This study reports a gneiss dome in the Hongseong area, southwestern margin of the Gyeonggi massif. This gneiss dome, named here as 'Oseosan dome' because it is located around the Oseosan, the highest peak along the western coastal area, is composed mainly of the Neoproterozoic to Paleozoic ortho- and paragneiss, mafic metavolcanic rock, and metadolerite. Migmatization affected these rock units, in which leucocratic(granitic) materials derived from anatexis frequently occur as patch and vein parallel to or cutting through internal foliation. The Oseosan dome shows overall concentric geometry and outward-dipping internal foliation, but also partly complicatedly changeable or inward-dipping foliation. Taking available petrological and geochronological data into account, the Oseosan dome is interpreted to be exhumed quickly into the upper crustal level during the Late Triassic, accompanied in part with anatexis and granite intrusion. In addition, extensional shear zone intruded by the Late Triassic synkinematic granite and sedimentary basin have been reported around the Oseosan dome. These evidences possibly suggest that the Oseosan dome formed in closely associated with the Late Triassic extensional movement and diapiric flow. Alternatively, 1) thrust- or reverse fault-related doming or 2) interference between independent folds during structural inversion of the Late Traissic to Middle Jurassic sedimentary basin can be also considered as dome-forming process. However, considering the northern limb of the Oseosan dome, cutting by the Late Traissic granite, and the southern limb, cutting by contractional fault reactivated after the Middle Jurassic, it is likely that the domal structure formed during or prior to the Late Triassic.

• Korean Journal of Environmental Biology
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• v.27 no.2
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• pp.155-163
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• 2009

The Oriental white stork (Ciconia boyciana) is an endangered species in Korea as well as in the world. In order to provide information on foraging habitats for releasing storks to the wild, we studied the foraging behavior of the species according to different food densities and water levels. We released two individuals, male and female, after enclosing a study site with a fence and cutting out a part of two or three primary feathers. Research was conducted from 20 June to 16 August 2008 at Whawon-ri, Mewon-myung, Chungcheongbuk-do, South Korea. We investigated habitat patch usage, foraging efficiency, and foraging methods of the feeding individuals in the different food densities and water levels. The storks invested more for foraging time and trials, and they captured more food in a habitat of high food density than others. The female invested more time and captured food most in a habitat of lowest water depth while the male in a habitat of middle water depth. However, foraging efficiency did not differ significantly among habitats of food density and water depth, and only differed between male and female by ways of foraging method. From this study we suggest that the storks select foraging habitats and foraging methods under different conditions of food density and water depth.