• Title/Summary/Keyword: PAK4

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Estimation of Reliability of Real-time Control Parameters for Animal Wastewater Treatment Process and Establishment of an Index for Supplemental Carbon Source Addition (가축분뇨처리공정의 자동제어 인자 신뢰성 평가 및 적정 외부탄소원 공급량 지표 확립)

  • Pak, JaeIn;Ra, Jae In-
    • Journal of Animal Science and Technology
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    • v.50 no.4
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    • pp.561-572
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    • 2008
  • Responses of real-time control parameters, such as ORP, DO and pH, to the conditions of biological animal wastewater treatment process were examined to evaluate the stability of real-time control using each parameter. Also an optimum index for supplemental carbon source addition based on NOx-N level was determined under a consideration of denitrification rate by endogenous respiration of microorganism and residual organic matter in liquor. Experiment was performed with lab-scale sequencing batch reactor(SBR) and working volume of the process was 45L. The distinctive nitrogen break point(NBP) on ORP-and DO-time profiles, which mean the termination of nitrification, started disappearing with the maintenance of low NH4-N loading rate. Also the NBP on ORP-and DO-time profiles was no longer observed when high NOx-N was loaded into the reactor, and the sensitivity of ORP became dull with the increase of NOx-N level. However, the distinctive NBP was constantly occurred on pH(mV)-time profile, maintaining unique profile patterns. This stable occurrence of NBP on pH(mV)-time profile was lasted even at very high NOx-N:NH4-N ratio(over 80:1) in reactor, and the specific point could be easily detected by tracking moving slope change(MSC) of the curve. Revelation of NBP on pH(mV)-time profile and recognition of the realtime control point using MSC were stable at a condition of over 300mg/L NOx-N level in reactor. The occurrence of distinctive NBP was persistent on pH(mV)-time profile even at a level of 10,000mg/L STOC(soluble total organic carbon) and the recognition of NBP was feasible by tracing MSC, but that point on ORP and DO-time profiles began to disappear with the increase of STOC level in reactor. The denitrfication rate by endogenous respiration and residual organic matter was about 0.4mg/L.hr., and it was found that 0.83 would be accepted as an index for supplemental carbon source addition when 0.1 of safety factor was applied.

Evaluating the Efficiency of the Device in Shielding Scattered Radiation during Treatment of Carcinoma of the Penis (음경암의 방사선치료 시 자체 제작한 Device의 산란선 차폐 효과에 대한 유용성 평가)

  • Gim, Yang-Soo;Lee, Sun-Young;Lim, Suk-Gun;Gwak, Geun-Tak;Pak, Ju-Gyeong;Lee, Seung-Hoon;Hwang, Ho-In;Cha, Seok-Yong
    • The Journal of Korean Society for Radiation Therapy
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    • v.21 no.1
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    • pp.9-15
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    • 2009
  • Purpose: We evaluated the device that was created for maintaining the patient's setup and protecting the testicles from scattered radiation during treatment of carcinoma of the penis. Materials and Methods: The phantom testicles were made of vaseline cotton gauze and the device consisted of 5 mm of acryl box and 4 mm of lead shielding. $3{\times}3\;cm^2$, $4{\times}4\;cm^2$, $5{\times}5\;cm^2$, $6{\times}6\;cm^2$, $7{\times}7\;cm^2$ field sizes were used for this study and measurement was made at 4, 5, 6, 7, 8, 10 cm from the lower edge of the field for 10 times with lead shielding and without the shielding respectively. 200 cGy was delivered using 6 MV photons. Results: The scatted radiation without lead shielding at 4, 5, 6, 7, 8, 10 cm from the lower edge of the field were 14.8-4.7 cGy with $3{\times}3\;cm^2$, 15.7-5.2 cGy with $4{\times}4\;cm^2$, 17.6-5.5 cGy with $5{\times}5\;cm^2$, 19.9-6.6 cGy with $6{\times}6\;cm^2$, 22.2-7.6 cGy with $7{\times}7\;cm^2$ and the measured dose without lead shielding were 7.1-2.6 cGy with $3{\times}3\;cm^2$, 8.9-3.6 cGy with $4{\times}4\;cm^2$, 12.3-4.8 cGy with $5{\times}5\;cm^2$, 14.6-5.0 cGy with $6{\times}6\;cm^2$ and 21.1~6.4 cGy with $7{\times}7\;cm^2$. As shown above, the scatted radiation decreased after using lead shielding. Depending of the range of field sizes, the resulting difference between without shielding values and with shielding values were: 7.8-1.1 cGy at 4 cm, 5.1-1.2 cGy at 5 cm, 3.8-1.1 cGy at 6 cm, 3.4-1.7 cGy at 7 cm, 2.8-1.7 cGy at 8 cm, 2.4-2.5 cGy at 9 cm and 2.1-1.8 cGy at 10 cm. In the situation as described above, the range in values depending on the distance was 7.8-1.1 cGy with $3{\times}3\;cm^2$, 6.9-1.6 cGy with $4{\times}4\;cm^2$, 5.3-0.8 cGy with $5{\times}5\;cm^2$, 5.3-1.5 cGy with $6{\times}6\;cm^2$ and 1.1-1.8 cGy with $7{\times}7\;cm^2$. Conclusion: Using the device we created to shield the testicles from scattered radiation during treatment of carcinoma of the penis, we have found that scattered radiation to the testicles is decreased by the phantom testicles, and by increasing the distance between the testicles and penis.

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Taxonomic reconsideration of Lactuca hallaisanensis H. Lév. (한라고들빼기 (Lactuca hallaisanensis H. Lév.)의 분류학적 재고)

  • Pak, Jae-Hong;Kim, Young-Ok;Choi, Kyung
    • Korean Journal of Plant Taxonomy
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    • v.31 no.4
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    • pp.311-319
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    • 2001
  • In order to evaluate taxonomic status of Latcuca hallaisanensis H. $L{\acute{e}}v$., an endemic species of the Jeju-do Island, we investigated fruit wall structure and chromosome morphology. The fruit wall structure had 10-11 obtuse costae in the transverse section. The costa was wholly occupied by libriform fiber cells, and the underlying fibersclereid tissue was only one to three cells layers thick. Also, the intercosta lacked fiber-sclereid layers. Somatic chromosome numbers and karyotype of Latcuca hallaisanensis were recorded for the first time. This diploid species (2n=10) with the same basic number of x=5 has the total chromosome length $23.3{\mu}m$ and the length of each chromosome falls in $1.9{\mu}m-2.9{\mu}m$. It possess the karyotype complement i.e., 3sm+2st and a characteristic chromosome pair (No. 1 and 2) with a secondary constriction at the distal portion of the short arms. The overall similarity in external morphology (involucre, achene etc), chromosome morphology as well as in fruit wall anatomy between Lactuca hallaisanensis and Crepidiastrum s. lat. clearly indicated that this species should be treated as Crepidiastrum, rather than Lactuca.

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Effects of Geological Conditions on the Geomorphological Development of the Southwestern Coastal Regions of Korea (서남해안지역(西南海岸地域)의 지형발달(地形發達)에 미친 지질조건(地質條件))

  • Kim, Suh Woon
    • Economic and Environmental Geology
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    • v.4 no.1
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    • pp.11-18
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    • 1971
  • The geotectonics and geomorphic structure of Korea resulted from the Song-rim Disturbance and the Daebo orogenic movements. Afterward this mountainous peninsula underwent several geological changes on a small scale, and it was also claimed that the steady rising of the elevated peneplain of the eastern coast and the submerging of the southwestern coastal area are largely due to the tilted block movement. These views have been generally accepted good in several ways, but they are limited in range or lacking in theoretical integration. The present writer investigated the geology of the Mt. Chi-ri-san and the Honam coal mining area for a geological map in 1965, respectively. The results of these studies convinced the present writer that the conventional views, which were based upon a theory of lateral pressure should be reconsidered in many respects, and more recent studies made it clear that the morphological development in the southwestern area can be better explained by the orogenic movement and rock control. The measurement of submerging speed of the western coastal area (Pak. Y. A., 1969) and a new account on the geology and tectonics of the Mid-central region of South Korea (Kim O.J., 1970) act as an encouragement to a new explanation. The present writer's researches on the extreme southwestern portion of the peninsula show that the steady submerging of this area cannot be attributed to a simple downthrown block phenomenon caused by block movement. It is no more than the result of the differential movement of uplifting in the eastern and western coastal areas and the rising of sea-level in the post-glacial period. This phenomenon could be easily explained by the comparison of the rate of rise in sea-level and amount of heat flow between Korea and other areas in the world. The existance of the erosional planes in the Sobaik-San ranges also provide an evidence of an upheaval in the western coast area. Though the Sobaik-San ranges largely follow the direction of the Sinian system. They consist of the numerous branches, whose trends run more or less differently from their main trend because of the disharmonic folding, are converged into Mt. Sobaik-San and Chupungryung. The undulation of the land is not wholely caused by orogenic movements, where as the present writer confirmed that the diversity of morphological development is the direct reflection of geological conditions such as rocks and processes which constitute the basic elements of geomorphic structure. An east-west directed mountain range which could be named as Hansan mountain range, was claimed to be oriented by the joint control. The geological conditions such as a special erosion and weathering of agglomerate and breccia tuff usually produce pot-hole like submarine features which cause the whirling phenomenon at the southwestern coast channel.

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Study on the Correlation between Digital Infrared Thermal Imaging-induced Severity of Cold Hypersensitivity of Hands and Feet and Heart Rate Variability (Digital Infrared Thermal Imaging에 따른 수족냉증 중증도와 Heart Rate Variability의 상관관계 연구)

  • Woo, Hye-Lin;Pak, Yeon-Kyeong;Kim, Joon-Ho;Park, Kyoung-Sun;Hwang, Deok-Sang;Lee, Jin-Moo;Jang, Jun-Bock;Lee, Chang-Hoon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.29 no.3
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    • pp.1-9
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    • 2016
  • Objectives: Cold Hypersensitivity of Hands and Feet (CHHF) has been diagnosed objectively by Digital Infrared Thermal Imaging (DITI) and has been known to be associated with autonomic nervous system (ANS), which can be assessed by Heart Rate Variability (HRV). This study evaluated the correlation between severity of CHHF and HRV variables.Methods: We studied 155 non-menopausal women with CHHF who visited Kyung Hee University Hospital at Gangdong from 01 October 2013 to 30 April 2016. We measured DITI and HRV of each patient. We used DITI to calculate the severity of CHHF with thermal difference between upper arm (L4, 俠白穴) and palm (P8, 勞宮穴) of both hands and anterior thigh (ST32, 伏兎穴) and dorsum of foot (LI3, 太衝穴) of both feet. The correlation between severity of CHHF and HRV variables were analyzed.Results: In time domain analysis, there was significantly positive correlation between the severity of CHHF and both SDNN and RMSSD. In frequency domain analysis, there was significantly positive correlation between the severity of CHHF and TP, HF and HF Norm while there was significantly negative correlation between the severity of CHHF and LF Norm as well as between the severity of cold hypersensitivity of both hands and LF/HF ratio.Conclusions: The more severe CHHF is, the more increased the function of parasympathetic nerve system (PNS) and relatively decreased the function of sympathetic nerve system (SNS) is. Also, it has known that cold hypersensitivity could be caused by deficiency syndrome and qi deficiency has the same ANS tendency as CHHF. Therefore, in practical fields, this result can be helpful in planning treatment and deciding prognosis in respect of deficiency syndrome.

Antioxidative Effect of Extracts from Different Parts of Kohlrabi (콜라비 부위별 추출물의 항산화 효과)

  • Pak, Won-Min;Kim, Koth-Bong-Woo-Ri;Kim, Min-Ji;Kang, Bo-Kyeong;Bark, Si-Woo;Kim, Bo-Ram;Ahn, Na-Kyung;Choi, Yeon-Uk;Yoon, Sung-Ryul;Ahn, Dong-Hyun
    • Journal of Applied Biological Chemistry
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    • v.57 no.4
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    • pp.353-358
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    • 2014
  • Antioxidant activities of ethanol and water extracts of flesh, leaves, and peels of green and purple Kohlrabi were measured by rancimat method, total phenolic compound (TPC), DPPH radical scavenging effect, chelating effect, and reducing power analysis. The highest TPC was observed in ethanol extract from green peel and water extract from purple leaf with 12.00 and 11.70 mg/g of dry sample, respectively. The ethanol extracts from purple Kohlrabi leaf and peel exhibited strong DPPH radical scavenging effects with reducing power while water extracts from purple Kohlrabi leaf and peel also showed strong DPPH radical scavenging with chelating effects. Antioxidant index of ethanol and water extracts from green and purple Kohlrabi measured by rancimat was lower than butylated hydroxytoluene. These results suggest that extracts from purple Kohlrabi leaf and peel exhibited higher antioxidant activities than those of green Kohlrabi, and can be potentially used as proper natural antioxidants.

Correction Factors for Outdoor Concentrations of PM2.5 Measured with Portable Real-time Monitors Compared with Gravimetric Methods: Results from South Korea

  • Yun, Dong-Min;Kim, Myeong-Bok;Lee, Jun-Bok;Kim, Bo-Kyeong;Lee, Dong-Jae;Lee, Seon-Yeub;Yu, Sol;Kim, Sung-Roul
    • Journal of Environmental Science International
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    • v.24 no.12
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    • pp.1559-1567
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    • 2015
  • This study investigated the association between $PM_{2.5}$ concentrations obtained with portable real-time monitors and those obtained with gravimetric methods in national urban air-quality monitoring sites in Seoul, South Korea. We used the SidePak AM510 Personal Aerosol Monitor (TSI Inc., 500 Cardigan Road Shoreview, MN) and DustTrak DRX 8533 (TSI Inc., 500 Cardigan Road Shoreview, MN) as portable real-time monitors for measuring $PM_{2.5}$ concentrations and compared these values with those measured with the PMS-103 or SEQ 47/50 models operated by Federal Reference Method (FRM) or the European Committee for Standardization(ECS), respectively, in national urban air-quality monitoring sites in Seoul. Measurements were conducted every other day in the winter and spring seasons of 2014. The estimated daily mean concentrations of $PM_{2.5}$ ranged between 13.4 and $161.9{\mu}g/m^3$ using AM 510 and between 22.0 and $156.0{\mu}g/m^3$ using DustTrak. The Spearman correlation coefficient for $PM_{2.5}$ concentrations between AM 510 and gravimetric results was 0.99, and the correlation between DustTrak and gravimetric results was 0.87. The correction factor suggested was 0.42 and 0.29 for AM 510 and DustTrak, respectively. We found that $PM_{2.5}$ concentrations measured with real-time monitors could overestimate true $PM_{2.5}$ concentrations and therefore the application of a correction factor (0.43) is strongly suggested for quantification when Real-time monitors were operated of $PM_{2.5}$ levels at urban atmospheric environment of South Korea.

The effects of exogenous insulin-like growth factor-I on broiler chicken growth (외인성 insulin-like growth factor-I이 육계의 성장에 미치는 영향)

  • Lee, Ho-il;Lee, Moon-joon;Lee, Dae-yeoul;Kim, Young-ann;Kang, Chang-won;Chon, Seung-ki
    • Korean Journal of Veterinary Research
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    • v.34 no.3
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    • pp.457-463
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    • 1994
  • Insulin-like growth factor-I(IGF-I) plays an important role in the regulation of mammalian and poultry growth. IGF-I has many actions in different tissues, which include metabolic, mitogenic, and differentiative actions. IGF-I induces insulin-like effects - such as increased cell glucose uptake and glycogen sysnthesis, however several physiological actions of IGF-I may not have been identified yet. In order to investigate the effect on growth in broiler chicken treated with exogenous insulin-like growth factor-I, 30 chickens were injected $50{\mu}g$ reconbinant human IGF- I (rhIGF- I ) per kg body weight as experimental group and 30 ckickens saline subcutanously as control, 3 times according to ages from 2 to 35 days. We established radioimmunoassay method by which we can measure chicken IGF- I (cIGF- I ) as in rhIGF- I assay. The results obtained were as follows; 1) The dilution curve showed in parallelism between rhIGF- I and cIGF- I in the Sep-pak $C_{18}$ cartridge plasma extracts. 2) The body weight of broiler chicken were significantly increased at 31 days($1,176.50{\pm}99.79g$) and 35 days($1,252.84{\pm}125.21g$) of age in treatment groups, compared with control group($1,011.88{\pm}40.22g,\;1,111.32{\pm}153.67g$). The liver and kidney weights on 35 days$(35.24{\pm}5.18g,\;11.05{\pm}1.47g)$ were significantly higher in rhIGF- I treated group than control group($30.95{\pm}4.04g,\;10.01{\pm}1.60g$) 3) The plasma concentration of IGF- l and total protein in rhIGF- I treated group were $58.17{\pm}1.69ng/ml$, $3.75{\pm}0.62g/dl$ respectively compared with control group $45.70{\pm}1.64ng/ml$, $2.32{\pm}0.53g/dl$. The results suggest that exogenous rhIGF- I increased total body weight, liver and kidney weights in broiler chicken, and it may increase IGF- I and total protein concentration in serum.

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Quality Characteristics of Sponge Cakes with Added Rice Flour Produced by Modified Genoise Method (변형 제누아즈법으로 만든 쌀가루 첨가 스폰지 케이크의 품질 특성)

  • Pak, Hee-Ok;Jang, Jae-Seon;Sohn, Chun-Young
    • The Korean Journal of Food And Nutrition
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    • v.23 no.4
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    • pp.607-614
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    • 2010
  • The aim of this study was to investigate the quality characteristics of sponge cakes with added rice flour produced by a modified genoise method to prevent volume reduction. A control group and experimental group I were prepared by the genoise method and experimental groups II, III, and IV were produced by a modified genoise method in which they were mixed with wheat flour and water to a make paste to form gluten for 3, 6, and 9 minutes, respectively. One third of the wheat flour in all experimental groups was replaced by rice flour. The control and experimental groups were compared in terms of quality characteristics, including batter specific gravity, volume, color, textural characteristics, and sensory qualities, to determine the optimal pasting time for wheat flour in the formulation. The specific gravity of the experimental groups was higher than that of the control and decreased with increasing wheat flour pasting time. The volume of experimental group I was lower than that of the control group, and the volume values of experimental groups III and IV, made by the modified genoise method, were higher than that of the control group. $dL^*$ and $db^*$values for the crust and inside of the cake were lower in the experimental groups than in the control. The $dL^*$ value, indicating brightness, increased as pasting time increased. The hardness values of experimental groups I and IV were higher than that of the control whereas experimental groups II and III had lower hardness values. Chewiness was higher in the control group, as well as experimental groups I and IV than in the experimental groups II and III. The gumminess of experimental group IV was highest. Cohesiveness decreased by adding rice flour to the sponge cake. Sensory attributes of cell uniformity, tenderness, moistness, taste, and overall acceptability had the highest scores in experimental group III. Based on these results, we conclude that the quality of sponge cake containing one third of the wheat flour replaced by rice flour is best with 6 minutes pasting of the wheat flour to form gluten.

The study on the metabolism of benzidine in the isolated perfused rat liver (흰쥐의 적출 간 관류법을 이용한 벤지딘 대사에 관한 연구)

  • Bae, Mun Joo;Roh, Jae Hoon;Cho, Young Bong;Kim, Choon Sung;Chun, Mi Ryoung;Kim, Chi Nyon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.6 no.1
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    • pp.28-37
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    • 1996
  • Benzidine, an aromatic amine used primarily in the manufacture of azo dyes, is recognized as a urinary bladder carcinogen in humans. In rats, mice, and hamsters, chronic exposure to benzidine resulted in tumors of the liver. The present study was undertaken to suggest analyzing the metabolites of benzidine with the optimal condition, identify the metabolites of benzidine, and observe time variance of the metabolites in the isolated perfusated rat liver. N-acetylbenzidine was synthesized by acetylation of benzidine with acetic anhydride and separated by thin layer chromatography(TLC) and high performance liquid chromatography(HPLC). To analysis benzidine and the metabolites of benzidine, HPLC operating condition has been optimized by means of preliminary experiment. The mobile phase consisted of acetonitrile(37%) in phosphate buffer, flow rate maintained at 1.0 ml/min. Optimal detective conditions were electrochemicaldetector(ECD) at 0.75 V for benzidine and N-acetylbenzidine and ultravioletdetector(UVD) at 287 nm for N,N'-diacetylbenzidine. The separation system was composed of a guard column and a separation column(Polymer C18, $4.6{\times}250cm$) at a temparature of $40^{\circ}C$. The perfusion system was equilibrated for 30 minutes before addition of benzidine to the perfusate. Samples of the perfusate were collected at time intervals(0, 10, 20, 30, 60, 90, 120 min) during the 2 hour perfusion. Before analyzing samples by HPLC/ECD/UVD, samples had been treated with sep-pak. Samples of perfusate analyzed by HPLC/ECD/UVD and the metabolites of benzidine in the isolated perfused rat liver were N-acetylbenzidine and N,N'-diacetylbenzidine. Benzidine metabolized over 60% during the initial 30 minutes of perfusion, extensively by 1 hour, and was undetectable in the perfusate. N-acetylbenzidine increased by 30 minutes of perfusion, declined. N,N'-diacetylbenzidine increased the 0-90 minutes period, remained constant during the 90-120 minutes period.

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