• The Journal of Korean Institute of Communications and Information Sciences
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• v.37C no.9
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• pp.791-801
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• 2012

Currently, SEAMCAT has been widely used as a tool to evaluate the effects of interference among a variety of wireless communication systems. This supports various channel propagation models, all of which are based on some statistical models for the channel propagation and do not exploit any specific terrain characteristics. Thus it is not appropriate for assessing the effects of interference between wireless systems, given some specific terrain features. In order to overcome this limit in its use, it is necessary to extend the capability of SEAMCAT to support a channel propagation model which takes into account terrain informations. The ITU-R P.526 is a familiar channel propagation model which calculates the path loss considering the terrain features. In this paper, we present an enhanced version of SEAMCAT which supports the ITU-R P.526 and provide a few examples of interference evaluation using it.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.2
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• pp.247-254
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• 2021

Problems such as a limited frequency resource and interference between adjacent bands have been continuously raised because of rapidly developing wireless technology and communication service. In order to solve that problem, government has been developed and operating the Spectrum Management Intelligent System(SMIS). This paper compares the results simulated by SMIS with the ATDI and the Matlab coded provided by ITU-R for verification of SMIS operating for the public interests. The Recommendation ITU-R P.526, P.1546, and P.1812 among the propagation model loaded in SMIS were chosen because of the relation to the broadcasting service. The comparison and analysis result shows that the outputs derived by SMIS has the small error of less than 1 dB. This research could be utilized for the policy establishment and R&D for the frequency allocation and the interference between adjacent bands.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1986.12a
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• pp.526.1-526
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• 1986

세균내 glutathione의 동태를 연구하기 위한 일환으로 P. mirabilis로부터 cysteinylglycine 분해효소를 정제 검토하였다. 본 균이 생산하는 cysteinylglycine 분해효소의 정제는 무세포추출액에 비해 비활성이 10배 증가하였고 0.68%의 낮은 수율을 나타내었다. 본 호소는 (NH$_4$)$_2$ SO$_4$ 침전과정에서 활성을 크게 손실하는 등 정제과정에서 불안정하였으며 투석 중에 형성하는 불용성 침전물은 4% Trition X-100 처리에 의해 효과적으로 용해되었다.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1986.12a
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• pp.526.2-526
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• 1986

P. mirabilis 로부터 정제한 cysteinylglycine 분해효소의 성질 및 세포내 국재성을 검토하였다. 본 효소의 일반적 성질은 pH가 7.3 온도 37$^{\circ}C$에서 최대 활성을 냐타내었으며 pH 8.0에서 안정하였고, 열안정성은 $50^{\circ}C$, 30분처리에 30%의 활성 손실을 보였다. 또한 $Mn^{+2}$이온과 $Mg^{+2}$ 이온에 의해 활성이 촉진되었으며 본 효소를 반응전 30분 Preincubation 하므로서 최대 활성을 보였다. 본 효소는 glutathione 일단계 분해효소인 ${\gamma}$-glutamyl transpeptidase와 마찬가지로 세포내의 periplasmic space에 존재하였다.

• Tuberculosis and Respiratory Diseases
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• v.80 no.3
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• pp.270-276
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• 2017

Background: A disputed rpoB mutation is a specific type of rpoB mutation that can cause low-level resistances to rifampin (RIF). Here, we aimed to assess the frequency and types of disputed rpoB mutations in Mycobacterium tuberculosis isolates from South Korea. Methods: Between August 2009 and December 2015, 130 patients exhibited RIF resistance on the MTBDRplus assay at Asan Medical Center. Among these cases, we identified the strains with disputed rpoB mutation by rpoB sequencing analysis, as well as among the M. tuberculosis strains from the International Tuberculosis Research Center (ITRC). Results: Among our cases, disputed rpoB mutations led to RIF resistance in at least 6.9% (9/130) of the strains that also exhibited RIF resistance on the MTBDRplus assay. Moreover, at the ITRC, sequencing of the rpoB gene of 170 strains with the rpoB mutation indicated that 23 strains (13.5%) had the disputed mutations. By combining the findings from the 32 strains from our center and the ITRC, we identified the type of disputed rpoB mutation as follows: CTG511CCG (L511P, n=8), GAC516TAC (D516Y, n=8), CTG533CCG (L533P, n=8), CAC526CTC (H526L, n=4), CAC526AAC (H526N, n=3), and ATG515GTG (M515V, n=1). Conclusion: Disputed rpoB mutations do not seem to be rare among the strains exhibiting RIF resistance in South Korea.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.167-167
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• 2017

Our previous study for developing seeds of Iksan 526 (I.526), an inbred line of resveratrol-producing transgenic rice line, showed that, in 20 days after heading (DAH) seeds, resveratrol was almost saturated and accumulation of piceid was highest though the expression of Arachis hypogaea resveratrol synthase 3 (AhRS3, GenBank DQ124938) was highest in 31 DAH seeds. In this study, it was investigated how the overexpression of AhRS3 affects phenylpropanoid pathway genes. p-Coumaroyl-CoA is derived from phenylpropanoid pathway and used as a substrate of AhRS3 reaction for resveratrol production. In 6, 13, 20, 31 and 41 (45 for Dongjin) DAH seeds of I526 and Dongjin, a wild type of I.526, respectively, the expression pattern of phenylpropanoid pathway genes, including phenylalanine ammonia-lyase (PAL: LOC_Os02g41630.2, LOC_Os04g43760.1), cinnamate 4-hydroxylase (C4H: LOC_Os05g25640.1), 4-coumarate-CoA ligase (4CL: LOC_Os02g08100.1), cinnamoyl-CoA reductase (CCR: LOC_ Os09g25150.1, LOC_Os08g34280.1), hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyl transferase (HCT: LOC_Os04g42250.2, LOC_Os02g39850.1) and cinnamyl alcohol dehydrogenase (CAD: LOC_Os02g09490.1), was examined using real time (RT)-PCR. Compared to developing seeds of Dongjin, RT-PCR results showed that the expression pattern of phenylpropanoid pathway genes was modified in developing seeds of I.526. In most genes, except for CAD, of I.526 developing seeds, the gene expression was highest in 20 DAH corresponding to biosynthesis of resveratrol and piceid, i.e. the expression of phenylpropanoid pathway genes was gradually increased by 20 DAH and decreased as seeds develop. Especially, in Dongjin, the highest expression of PALs and 4CL was in 6 DAH and their expression was gradually decreased as seeds develop. These genes expression data also exhibited that, in developing seeds of I.526, phenylpropanoid pathway genes were slightly or significantly (in some genes) upregulated compared to Dongjin. Therefore, the overexpression of AhRS3 changed the expression pattern of phenylpropanoid pathway genes in I.526 developing seeds and this modification for gene expression is closely related to biosynthesis of resveratrol and piceid.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.105-105
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• 2017

Our previous study for developing seeds of Iksan 526 (I.526), an inbred line of resveratrol-producing transgenic rice line, showed that, in 20 days after heading (DAH) seeds, resveratrol was almost saturated and accumulation of piceid was highest though the expression of Arachis hypogaea resveratrol synthase 3 (AhRS3, GenBank DQ124938) was highest in 31 DAH seeds. In this study, it was investigated how the overexpression of AhRS3 affects phenylpropanoid pathway genes. p-Coumaroyl-CoA is derived from phenylpropanoid pathway and used as a substrate of AhRS3 reaction for resveratrol production. In 6, 13, 20, 31 and 41 (45 for Dongjin) DAH seeds of I526 and Dongjin, a wild type of I.526, respectively, the expression pattern of phenylpropanoid pathway genes, including phenylalanine ammonia-lyase (PAL: LOC_Os02g41630.2, LOC_Os04g43760.1), cinnamate 4-hydroxylase (C4H: LOC_Os05g25640.1), 4-coumarate-CoA ligase (4CL: LOC_Os02g08100.1), cinnamoyl-CoA reductase (CCR: LOC_Os09g25150.1, LOC_Os08g34280.1), hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyl transferase (HCT: LOC_Os04g42250.2, LOC_Os02g39850.1) and cinnamyl alcohol dehydrogenase (CAD: LOC_Os02g09490.1), was examined using real time (RT)-PCR. Compared to developing seeds of Dongjin, RT-PCR results showed that the expression pattern of phenylpropanoid pathway genes was modified in developing seeds of I.526. In most genes, except for CAD, of I.526 developing seeds, the gene expression was highest in 20 DAH corresponding to biosynthesis of resveratrol and piceid, i.e. the expression of phenylpropanoid pathway genes was gradually increased by 20 DAH and decreased as seeds develop. Especially, in Dongjin, the highest expression of PALs and 4CL was in 6 DAH and their expression was gradually decreased as seeds develop. These genes expression data also exhibited that, in developing seeds of I.526, phenylpropanoid pathway genes were slightly or significantly (in some genes) upregulated compared to Dongjin. Therefore, the overexpression of AhRS3 changed the expression pattern of phenylpropanoid pathway genes in I.526 developing seeds and this modification for gene expression is closely related to biosynthesis of resveratrol and piceid.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.10
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• pp.13-20
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• 2013

Currently, SEAMCAT has been widely used as a tool to evaluate the effects of interference among wireless communication systems. In the previous work, we have incorporated the ITU-R P.526 pathloss model to the existing SEAMCAT in order to support the capability of interference evaluation taking into account any specific terrain characteristics. Along with this, we have implemented a terrain display function based on the Google map. However, the two-dimensional Google map based display is not effective in helping users to figure out some terrain features including the elevation variation in a given region. In order to alleviate this difficulty, we have incorporated the three-dimensional terrain display using the API of the Google earth to the existing SEAMCAT and provided the capability of viewing the positions of the associated communication systems, the variation of the carrier intensity and interference intensity in location, shadow region indication, and line-of-sight analysis and presented an example of interference evaluation.

• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1049-1055
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• 2018

Purpose: To investigate the factors associated with glaucoma in patients with pseudoexfoliation syndrome by comparing features of the anterior segments and ocular biometry according to the presence or absence of open-angle glaucoma in pseudoexfoliation syndrome. Methods: We analyzed 96 patients (115 eyes) diagnosed as having pseudoexfoliation syndrome in this study. The patients were divided into two groups of simple pseudoexfoliation syndrome (64 patients, 76 eyes) and pseudoexfoliation glaucoma (32 patients, 39 eyes). We compared the age, sex, underlying disease, location of pseudoexfoliative material, iris change, degree of nuclear cataract, pupil dilatation, corneal endothelial cell counts, central corneal thickness, anterior chamber depth, axial length, corneal curvature, and intraocular pressure (IOP). Results: There were no significant differences between the two groups in terms of age (p = 0.694), sex (p = 0.161), diabetes (p = 0.440), hypertension (p = 0.238), pseudoexfoliative material observed in anterior capsule (p = 0.700), pupillary margin (p = 0.210), iris depigmentation (p = 0.526), pupillary ruff loss (p = 0.708), degree of nuclear cataract (p = 0.617), pupil dilatation (p = 0.526), central corneal thickness (p = 0.097), anterior chamber depth (p = 0.283), axial length (p = 0.095), or horizontal and vertical corneal curvature (p = 0.066 and 0.306, respectively). In pseudoexfoliation glaucoma, significantly higher IOP (p = 0.026), a high frequency of membrane formation (p = 0.047), and decreased corneal endothelial cell counts (p = 0.048) were observed. Conclusions: Pseudoexfoliation syndrome with open-angle glaucoma was shown to be associated with high IOP, decreased corneal endothelial cell counts, and a high frequency of membrane formation. Therefore, when such changes are observed in pseudoexfoliation syndrome patients, a higher risk of open-angle glaucoma should be recognized, and careful attentionis required accordingly.

• Journal of Digital Convergence
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• v.15 no.10
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• pp.537-549
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• 2017

This purpose of this study was to investigate self-esteem, body image and depression in infertile women and to identify factors influencing depression. There were statistically significant difference in self-esteem on variables such as age, education, occupation, pressure of treatment cost. There were statistically significant difference in body image on variables such as period of marriage, education, pressure of treatment cost. There were statistically significant difference in depression on variables such as age, education, family structure, pressure of treatment cost. Self-esteem was positively correlated with body image(r=.688, p=.000). Depression was negatively correlated with self-esteem(r=-.710, p=.000) and body image(r=-.526, p=.000). Factors influencing depression were self-esteem(b=-0.66, p=.000), Living with parents-in-law(b=-7.92, p=.001), and age over 40 years(b=-1.72, p=.033), which explained 63.5%.