• 제목/요약/키워드: P-value Method

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메타분석에서 새로운 P-Value 결합 방법 (New Method for Combining P-values in Meta-Analysis)

  • 선정연;김동재
    • 응용통계연구
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    • 제26권5호
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    • pp.797-806
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    • 2013
  • 메타분석은 이전의 연구들의 결과를 결합하기 위해 많은 분야에서 널리 사용된다. 메타분석 방법들 중에 p-value의 통합은 가장 단순한 방법이며 Tippett (1931), Fisher (1932) Stouffer 등 (1949) 등이 p-value를 통합하는 다양한 방법들을 제안하였다. 이 논문에서 우리는 지수분포에 기초한 새로운 p-value의 통합 방법을 제안하였다. 또한, 몬테카를로 모의시험 연구를 통해 제안된 방법과 이전의 방법들의 검정력을 비교하였다.

Improved Mid P-value Method for Statistical Inference in Three-Way Contingency Tables

  • Donguk Kim
    • Communications for Statistical Applications and Methods
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    • 제5권3호
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    • pp.905-926
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    • 1998
  • We propose a modified mid P-value method to reduce the conservativeness for the inference of conditional associations in three-way contingency tables. This improves the ordinary mfd P-value method. For $2{\times} 2${\times} K$ tables, we propose confidence intervals for an assumed common odds ratio based on inverting two separate one-sided tests using the modified mid P-value. Also, an alternative and usually even better ways of constructing intervals, based on Inverting a two-sided test, are presented. The actual probability of coverage of a 100($1-\alpha$)% confidence interval is centered about the nominal level, but the modified mid P-value approach gives actual coverage probability even closer to the nominal level than the ordinary mid P-value approach.

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MBOD법에 의한 낙동강의 조류증식 제한인자 추정 (Evaluation of Algal Growth Limiting Factor in the Nakdong River by MBOD Method)

  • 송교욱;서인숙
    • 한국환경과학회지
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    • 제4권5호
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    • pp.469-479
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    • 1995
  • The increase of population and industrial activities had brought into eutrophication in the Nakdong river. A remarkable acceleration of eutrophication brought about serious problems for water supply. Therefore, for the purpose of conservation of water quality in the Nakdong river it is necessary to control nutrients. MBOD method was use to evaluate algal growth limiting factor and algal growth potential in the Nakdong river from June to August 1994. The modified biochemical oxygen demand(MBOD) depends on the amount of available inorganic nutrient and organic substrate during 5 day incubation in the dark at 2$0^{\circ}C$. The MBOD assay depends on inorganic nutrients such as P and N as well as reduced carbon and called the MBOD, the MBOD-P, and the MBOD-N, respectively. The results of bioassay by MBOD(Modified BOD) method showed that the MBOD, MBOD-P and MBOD-N value were found to be in the ranges of 3.8~96.0 mg$O_2$/l, 5.6~94.0 mg$O_2$/l and 42.0~220 mg$O_2$/l, respectively. And the the bioassay value was found to be the highest in Koryong area and the lowest in Waekwan area throughout the Nakdong river. The variations of MBOD-P and MBOD-N value showed similar tendencies to the variations of phosphorus and nitrogen value, respectively. By MBOD method, the relationships of MBOD, MBOD-P and MBOD-N value were MBOD ≒ MBOD-P 《 MBOD-N. The MBOD value was nearly equal to the MBOD-P value, and the MBOD-N value was 3 to 20 times more than the MBOD-P value, approximately. Therefore, in the Nakdong river, phosphorus was the limiting factor for algal growth during summer season. The algal growth potential as the concentration of chlorophyll-a in the summer was maximum 5 times more than standing crop as it.

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퍼지 p-값에 의한 퍼지가설검정 (Fuzzy hypotheses testing by fuzzy p-value)

  • 강만기
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 2006년도 춘계학술대회 학술발표 논문집 제16권 제1호
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    • pp.199-202
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    • 2006
  • We propose some properties of fuzzy p-value and fuzzy significance level to the test statistics for the fuzzy hypotheses testing. Appling the principle of agreement index, we suggest two method for fuzzy hypothesis testing by fuzzy rejection region and fuzzy p-value with fuzzy hypothesis $H_{f,0}$.

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효모배지용 당밀의 청징법에 관하여 (Molasses clarifying method used by lime-phosphate for yeast culture)

  • 임억규
    • 미생물학회지
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    • 제19권3호
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    • pp.121-127
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    • 1981
  • The constituents of molasses and effect of pH precipitate formation in molasses solution, vary according to its producing districts. The formation of precipitation is not so changeable in the range of buffering zone of molasses solution(pH4.3-6.3) in philippine molasses according to the change of pH value. On lower or higher than the range of buffering zone, the precipitation is increased from pH 4.3 to 2.8 and from 6.3 to 8.1, it is decreased when pH value is lower or higher than the pH value range. For molasses clarifying, it had better adjust the pH of molasses solution to neutral or weak alkali range out of the alkai side of the buffering zone, with lime solution. And then, add the calcium super phosphate solution to pH value of alkali side in buffering zone, as much as the pH of clarified molasses solution can reach to middle value in buffering zone. For the equilibrium of pH value on clarifying molasses, it takes plenty of time more than 6 hours.

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식품 중 조단백질 정량을 위한 켈달법과 듀마스법 비교 연구 (A comparison study of crude protein contents obtained utilizing the Kjeldahl method and Dumas combustion method in foods)

  • 황선혜;구민선;조새롬;조용선
    • 분석과학
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    • 제33권3호
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    • pp.143-150
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    • 2020
  • 본 연구에서는 곡물, 육류, 해산물, 채소류등에 대하여 식품공전에 등재되어 있는 켈달법(Kjeldahl method)과 AOAC에 등재되어 있는 듀마스법(Dumas method)을 이용하여 조단백질을 비교 분석하였다. 두 시험법에 대해 총 31종의 시료를 3회 반복 시험한 결과 대부분 비슷한 결과를 나타내었다. 곡물류의 경우 백미를 포함 총 9 종을 분석하였고, 켈달법과 듀마스법 결과간의 상관관계를 비교한 결과 correlation coefficient가 0.994, p-value는 0.956로 두 결과값간의 유의적 차이는 없는 것으로 나타났다. 육류 9 종에 대해서는 correlation coefficient이 0.9725, p-value는 0.947, 해산물 5 종에 대해서는 correlation coefficient 값이 0.9879, p-value는 0.761, chemical시료 3종에 대해서는 correlation coefficient값이 0.9985, p-value는 0.997, 채소류 4 종에 대해서는 correlation coefficient값이 0.9873, p-value는 0.727로 시료간 약간의 차이는 있으나 켈달법과 듀마스법간에는 유의적 차이가 없는 것으로 나타났다. 육류의 경우 시료의 균질성이 좋지 않아 소량을 칭취하여 분석해야 하는 듀마스법에서 재현성이 좋지 않았다. 다만 시료 중 질산염을 많이 함유하고 있는 채소류의 경우 켈달법을 이용하여 분석시 완전한 분해가 이루어지지 않아 듀마스의 결과보다는 낮은 함량값을 나타내었다. 또한 듀마스 법의 경우 약 0.1 g의 적은 시료를 사용하여 분석하기 때문에 분석시 시료의 균질성이 보장되어야 한다. 두 시험법 모두 순단백질을 직접 정량하는 것이 아닌 질소 분석을 바탕으로 단백질 함량을 구하는 것이기 때문에 정확성이 높다고 할 수 없지만, 샘플의 특성에 따라 적절한 분석방법을 선택하여 분석하는 것이 중요하다.

Application of T1 Map Information Based on Synthetic MRI for Dynamic Contrast-Enhanced Imaging: A Comparison Study with the Fixed Baseline T1 Value Method

  • Dong Jae Shin;Seung Hong Choi;Roh-Eul Yoo;Koung Mi Kang;Tae Jin Yun;Ji-Hoon Kim;Chul-Ho Sohn;Sang Won Jo;Eun Jung Lee
    • Korean Journal of Radiology
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    • 제22권8호
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    • pp.1352-1368
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    • 2021
  • Objective: For an accurate dynamic contrast-enhanced (DCE) MRI analysis, exact baseline T1 mapping is critical. The purpose of this study was to compare the pharmacokinetic parameters of DCE MRI using synthetic MRI with those using fixed baseline T1 values. Materials and Methods: This retrospective study included 102 patients who underwent both DCE and synthetic brain MRI. Two methods were set for the baseline T1: one using the fixed value and the other using the T1 map from synthetic MRI. The volume transfer constant (Ktrans), volume of the vascular plasma space (vp), and the volume of the extravascular extracellular space (ve) were compared between the two methods. The interclass correlation coefficients and the Bland-Altman method were used to assess the reliability. Results: In normal-appearing frontal white matter (WM), the mean values of Ktrans, ve, and vp were significantly higher in the fixed value method than in the T1 map method. In the normal-appearing occipital WM, the mean values of ve and vp were significantly higher in the fixed value method. In the putamen and head of the caudate nucleus, the mean values of Ktrans, ve, and vp were significantly lower in the fixed value method. In addition, the T1 map method showed comparable interobserver agreements with the fixed baseline T1 value method. Conclusion: The T1 map method using synthetic MRI may be useful for reflecting individual differences and reliable measurements in clinical applications of DCE MRI.

연약지반에 있어 N치에 의한 기초공법 대책연구 (On the Counter Plan of Foundation Method being based on N-Value in the Soft-Ground)

  • 이용희;이대명
    • 한국항만학회지
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    • 제10권2호
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    • pp.69-90
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    • 1996
  • This study is related to save the bearing capacity from using Meyerhof formula namely, static mechanics formula with the S.P.T(N value) of the soft ground and is to choose the soft ground improvement method by the using of total load for the proper method of the pile foundation and then to design the most suitable pile foundation to fit the actual circumstance. The purpose of this study is calculating the diameter of the pile foundation by static mechanics formula and introducing the optimum design condition from the result of the bearing capacity for using N value of the S.P.T obtained from the deep soft ground about the piles such as P.H.C pile, pipe and cast-in-place pile of big diameter, etc. As above-mentioned, it is considered that the use of P.H.C pile or pipe pile is advisable on the synthetical investigation and that the selection of cast-in-place pile method is desirable in terms of the constructive safety and durability.

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김치숙성도 판정기준을 위한 신속 검사법 Resazurin-test 에 관한 연구 (Study on the Resazurin test as a Rapid Method for the Estimation of Maturity of Kimchi)

  • 우순자;이혜준
    • 한국식품과학회지
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    • 제19권3호
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    • pp.250-256
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    • 1987
  • 김치숙성도를 객관적으로 평가하기 위하여 배추김치, 깍두기, 오이김치 및 호남식 매운김치를 시료로 $25^{\circ}C$$4^{\circ}C$ 에서 저장하면서 pH, total acidity, volatile acidity, resazurin value, sensory value, volatile basic nitrogen, Vitamin C와 NaCl를 분석하고 임상용 test봉을 이용하여 glucose와 Nitrite를 정성분석 하였다. 김치숙성도에 따라 pH, Vit.C와 glucose는 감소하고 total 및 volatil acidity, resazurin value와 sensory sauer value는 증가하고 NaCl은 변함이 없었다. Nitrite는 산도가 높아질수록 감소하거나 사라지는 경향으로 나타났다. 김치숙성도에 따라 가장 뚜렷하게 변하는 인자는 pH, total acidity와 resazurin value로서 sensory value와 상관성이 모두 높았다. Resazurin test value는 김치 저장온도와 시료검액 회석농도에 따라 차이가 있었으므로 시료 검액을 2%와 4%로 고정하고 적숙기 핑가기준을 냉장저장 김치에선 각각 2점과 4점, 실온저장 김치에선 2% 검액으로 4점을 기준으로 하면 resazurin test 방법이 김치숙성도 신속검사법으로 활용할 수 있음을 확인할 수 있었다.

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MBOD법에 의한 낙동강의 조류증식 제한인자 추정 (Evaluation of Algal Growth Limiting Factor in the Nakdong River by MBOD Method)

  • 송교욱;서인숙;신성교;이석모;박청길
    • 한국환경과학회지
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    • 제4권5호
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    • pp.83-83
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    • 1995
  • The increase of population and industrial activities had brought into eutrophication in the Nakdong river. A remarkable acceleration of eutrophication brought about serious problems for water supply. Therefore, for the purpose of conservation of water quality in the Nakdong river it is necessary to control nutrients. MBOD method was use to evaluate algal growth limiting factor and algal growth potential in the Nakdong river from June to August 1994. The modified biochemical oxygen demand(MBOD) depends on the amount of available inorganic nutrient and organic substrate during 5 day incubation in the dark at 20$^{circ}C$. The MBOD assay depends on inorganic nutrients such as P and N as well as reduced carbon and called the MBOD, the MBOD-P, and the MBOD-N, respectively. The results of bioassay by MBOD(Modified BOD) method showed that the MBOD, MBOD-P and MBOD-N value were found to be in the ranges of 3.8∼96.0 mg$O_2$/l, 5.6∼94.0 mg$O_2$/l and 42.0∼220 mg$O_2$/l, respectively. And the the bioassay value was found to be the highest in Koryong area and the lowest in Waekwan area throughout the Nakdong river. The variations of MBOD-P and MBOD-N value showed similar tendencies to the variations of phosphorus and nitrogen value, respectively. By MBOD method, the relationships of MBOD, MBOD-P and MBOD-N value were MBOD ≒ MBOD-P 《 MBOD-N. The MBOD value was nearly equal to the MBOD-P value, and the MBOD-N value was 3 to 20 times more than the MBOD-P value, approximately. Therefore, in the Nakdong river, phosphorus was the limiting factor for algal growth during summer season. The algal growth potential as the concentration of chlorophyll-a in the summer was maximum 5 times more than standing crop as it.