• Title/Summary/Keyword: P-Turn

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Conformation of Substance P in Neutral Phospholipid Micelles

  • Kim, Seonggeum;Eunjung Bang;Kim, Yangmee
    • Journal of the Korean Magnetic Resonance Society
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    • v.2 no.1
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    • pp.41-49
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    • 1998
  • A linear undecapeptide, Substance P (SP) is involved in a wide variety of physiological processes such as pain, inflammation, salivation, and hypertension. Tertiary structure of SP in dodecylphosphocholine (DPC) micelles has been investigated by CD, NMR spectroscopy, and DGII calculation. CD spectrum of SP in the presence of 7.5 mM DPC micelles does not show any favorable secondary structure. The tertiary structure determined by NMR spectroscopy and DGII calculation shows that the Phe7-Phr8-Gly9-Leu10 region adopts a turn structure, while the N-terminal region is quite flexible. Both prolines in SP exist preferentially as the trans isoforms and the aromatic ring of Phe7 protrudes outward. Conformation of SP may be restrained by the contact of the Phe7 aromatic ring with the hydrophobic side chains of the DPC micelles and this interaction induces a turn structure. Structure of SP in aqueous solution in the presence of DPC micelles can represent a good model to study the conformation recognized by the receptor near neutral membrane.

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Physical Modeling of SiC Power Diodes with Empirical Approximation

  • Hernandez, Leobardo;Claudio, Abraham;Rodriguez, Marco A.;Ponce, Mario;Tapia, Alejandro
    • Journal of Power Electronics
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    • v.11 no.3
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    • pp.381-388
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    • 2011
  • This article presents the development of a model for SiC power diodes based on the physics of the semiconductor. The model is able to simulate the behavior of the dynamics of the charges in the N- region based on the stored charge inside the SiC power diode, depending on the working regime of the device (turn-on, on-state, and turn-off). The optimal individual calculation of the ambipolar diffusion length for every phase of commutation allows for solving the ambipolar diffusion equation (ADE) using a very simple approach. By means of this methodology development a set of differential equations that models the main physical phenomena associated with the semiconductor power device are obtained. The model is developed in Pspice with acceptable simulation times and without convergence problems during its implementation.

Analyses of Capacity and Lest-Turn Adjustment Factors for Permitted Left-Turn (비보호좌회전 보정계수 및 용량 분석)

  • 김경환;강남기
    • Journal of Korean Society of Transportation
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    • v.16 no.1
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    • pp.129-150
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    • 1998
  • 신호교차로에서의 효율적인 교통운영을 위해서는 비보호좌회전의 활성화가 필요하며 이를 위해서는 비보호좌회전이 허용되는 신호교차로에서의 교통운영의 정확한 분석이 가능해야한다. 본연구에서는 국내신호교차로에서의 운전자의 행태에 기초하여 USHCM의 비보호 좌회전 분석에서 요구되는 $g_f$, $g_q$, $P_L$, 의 현실적인 값을 산정하기 위한 모형이 제안되었으며 이에 기초하여 비보호좌회전 보정계수 및 용량분석 기법을 제시하였다. 본 연구의 결과는 다음과 같다. 첫째, 공용차로를 가진 비보호좌회전 신호교차로에서 주기당 좌회전교통량(LTC)이 5대까지의 범위에서 G(녹색신호시간)와 LTC를 변수로 한 $g_f$모형이 개발되었다. 둘째, $v_{olc}$$qr_o$를 변수로 한 $g_q$모형이 개발되었으며 제안된 모형에 의한 $g_q$값이 진주 및 광주에서의 현장관측치와 거의 일치함을 볼 수 있었다. 셋째, 1994 USHCM의 $P_L$모형이 LTC가 증가할수록 $P_L$값이 감소하는 비현실적인 모형의 구조를 가지므로 현실적인 모형의 구축을 위해 국내 현장자료에 기초하여 LTC를 변수로하여 $P_L$산정을 위한 단순화된 모형이 개발되었다. 넷째, 대향교통류를 통해 좌회전할 수 있는 유효녹색시간의 부분의 $g_u$를 산정하여 비보호좌회전 포화교통류율($S_{LT}$)에 주기 대 $g_u$의 비를 곱한 비보호좌회전 용량산정식이 제안되었다.

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Optically-Triggered Silicon P-I-N Switches with Planar and Anistropically-Etched Structures (플레나 및 이방성 에칭 구조를 갖는 실리콘 p-i-n 광 스위치)

  • Min, Nam-Ki;Lee, Seong-Jae;Henderson, H.T.
    • Proceedings of the KIEE Conference
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    • 1997.07d
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    • pp.1261-1263
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    • 1997
  • Two kinds of optically-triggered p-i-n switches with planar and V-groove structures have been fabricated with gold-doped silicon. The V-groove device exhibits a higher threshold voltage and is more sensitive to light. The minimum optical power indicates that a certain minimum illumination is required to optically turn on the silicon p-i-n devices.

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2500V IGBTs with Low on Resistance and Faster Switching Characteristic (낮은 온-저항과 빠른 스위칭 특성을 갖는 2500V급 IGBTs)

  • Shin, Samuell;Koo, Yong-Seo;Won, Jong-Il;Kwon, Jong-Ki;Kwak, Jae-Chang
    • Journal of IKEEE
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    • v.12 no.2
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    • pp.110-117
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    • 2008
  • This paper presents a new Insulated Gate Bipolar Transistor(IGBT) based on Non Punch Through(NPT) IGBT structure for power switching device. The proposed structure has adding N+ beside the P-base region of the conventional IGBT structure. The added n+ diffusion of the proposed device ensure device has faster turn-off time and lower forward conduction loss than the conventional IGBT structure. But, added n+ region can reduce th breakdown voltage and latching current density of the proposed device due to its high doping concentration. This problems can be overcome by using diverter on the right side of the device. In the simulation results, turn-off time of the proposed device is 0.3us and the on-state voltage drop is 3V. The results show that the proposed device has superior characteristic than conventional structure.

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An Analysis on Micro-climate Characteristic of Apartments in Beijing, China Using ENVI-met Simulation (ENVI-met를 이용한 중국 베이징 아파트 하절기 미기후 특성 분석)

  • Wu, Jin-Dong;Lee, Jun-Hoo;Yoon, Seong-Hwan
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.35 no.8
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    • pp.169-176
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    • 2019
  • The purpose of this study was to analyze outdoor thermal comfort of apartments planning characteristic of pedestrian height in Beijing, China. Selecting 322 apartment complexes with more than 1000 households and more than 10 buildings(including 10 buildings), mainly in Chaoyang District and Tongzhou District to select 32 basic layout types and then 12 typical layout types were select in 32 basic layout types. Finally, the simulation was conducted for the 12 typical layout types using the micro-climate model ENVI-met to evaluate the wind environment, the thermal environment and the comfort. The results of this study as follows: In the parallel arrangement, it has the best outdoor thermal comfort of Slab-East-Parallel(S/E/P). Next is Slab-South-Parallel(S/S/P), Tower-South-Parallel(T/S/P) in turn. In the stagger arrangement, Mixture-South-North and South Stagger-1(M/S/NSS-1) has the best outdoor thermal comfort and Slab-South-North and South Stagger(S/S/NSS), Tower-South-North and South Stagger(T/S/NSS), Mixture-South-North and South Stagger-3(M/S/NSS-3), Mixture-South-North and South Stagger-4(M/S/NSS-4), Mixture-South-North and South Stagger-2(M/S/NSS-2) in turn. In the cluster arrangement, Mixture-Mixture-Cluster-2(M/M/C-2) has the best outdoor thermal comfort and Mixture-Mixture-Cluster-3(M/M/C-3), Mixture-Mixture-Cluster-1(M/M/C-1) in turn. Due to the low wind speed and high air temperature, it is necessary to consider the layout types that can form the wind road at first, such as Mixture-South-North and South Stagger-1(M/S/NSS-1), Slab-South-North and South Stagger(S/S/NSS) and so on.

Head Posture-Induced Phoria Deviation (머리 위치에 따른 사위도의 변화)

  • Ha, Eun-Mi;Son, Jeong-Sik;Moon, Byeong-Yeon;Yu, Dong-Sik
    • Journal of Korean Ophthalmic Optics Society
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    • v.15 no.2
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    • pp.155-160
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    • 2010
  • Purpose: The purpose of this study was to evaluate how phoria variations would vary with head positions, as well as to review the need to differentiate prism placement over either eye in a relation to the imbalance of the extraocular muscle. Methods: This study was carried out with 44 males (88 eyes) and 16 females (32 eyes) aged between 20 and 30. For all subjects, testings were performed using cover test, subjective refraction, phoria and vergence test. To analyze phoria variations comparatively for the head tilt test and the face turn test, phoria deviation were measured using the von Graefe. Results: For the phoria variation related with head tilt and face turn, a significant difference was observed in the group judged to be abnormal on the horizontal phoria of Morgan' norm (p<0.05); especially in patients who needed near prescription of Sheard's criterion, a higher variation was observed (p<0.05). The abnormal group was composed of patients who needed distance prescription of Sheard's criterion and ones who did not need the prescription, all of whom showed phoria variations, but the mean value was less than the near. Conclusions: With regard to the head tilt and face turn related phoria level, the patients who needed near horizontal prism prescription of Sheard's criterion showed a remarkably higher variation. Altogether, it is deemed to check whether extraocular muscles are ill-balanced in both eyes previously to determine the prism power on phoria level to the end that each of prism powers may be accurately determined.

Effects of the Head-Turn Gait on Gait Parameters in the Elderly (노인에서 머리회전을 동반한 보행이 보행변수에 미치는 영향)

  • Lee, Myoung-Hee;Chang, Jong-Sung
    • PNF and Movement
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    • v.19 no.3
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    • pp.435-440
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    • 2021
  • Purpose: The purpose of this study is to investigate the effects of older adult's head-turn gait on gait parameters by comparing with head oriented forward gait and to provide criteria for their risk of falling compared to young adult. Methods: The subjects were 19 young adults in their 20s and 18 older adults in their 60s or above residing in Daegu or Gyeongsangbuk-do. To evaluate their gait parameters, spatiotemporal gait parameters were measured using a gait analysis tool (Legsys, BioSensics, USA) under two conditions: 1) walking while keeping one's eyes forward and 2) walking while turning the head. The measurement for each test was performed after one practice session, and the mean value of three measurements was analyzed. The collected data were statistically processed using a two-way analysis of variance (ANOVA) to compare any differences in gait parameters between the two groups under the two conditions. The statistical significance level was set at α=0.05. Results: According to the comparison of gait parameters in young adult and older adult between the head oriented forward gait and head-turn gait, statistically significant differences were observed in two parameters: stride length according to the height ratio and stride speed obtained by dividing the stride length according to the height ratio by time (p<0.05). Conclusion: The results of this study indicate that the head-turn gait causes greater differences in stride length and speed among older adult than in young adult and therefore can act as a cause of falling.

USE OF ENZYMES FOR MODIFICATION OF DISSOLVED AND COLLOIDAL SUBSTANCES IN PROCESS WATERS OF MECHANICAL PULPING

  • Johanna Buchert;Annikka Mustrnata;Peter Spetz;Rainer Ekman;Kari Luukko
    • Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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    • 1999.11b
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    • pp.115-119
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    • 1999
  • During mechanical pulp production and blcaching wood components, such as extractives, carbohydrates and lignin are dissolved and dispersed into the process waters. These components are called dissolved and colloidal substances(DCS). DCS can accumulate during water circulation and can in turn affect paper machine runnability and also the strength and optical properties of the paper. In this work DCS fraction origination from TMP process were treated with enzymes acting on triglycerides. glucomannans, and lignin and the effect of enzymatic treatments on the water composition as well as sheet properies were evaluated. Lipases were found to modify the chemical structure of the extractives resulting in more hydrophilic fibre surface and subsequent improvement in the sheet strength properties. Mannanase treatment, on the other hand, destabilized pitch. As a result, aggregation of pitch to the fibres was observed which in turn resulted in impaired strength properties. Laccase could effectively polymerize lignans and the reaction products seemed to be sorbed onto the fibres.

A Study on the Formation Process and Sustainability of Community of Practice in Public Libraries (공공도서관 실행공동체의 형성과정과 지속가능성을 위한 연구)

  • Park, Seong-Woo
    • Journal of the Korean Society for Library and Information Science
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    • v.52 no.1
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    • pp.113-131
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    • 2018
  • The study is to prove the necessity of librarian as the coordinator for the building and sustenance of "Community of Practice" in public libraries. Therefore, The study reviews literatures and conducts a survey how librarians think of their work from the perspective of CoP. The results of this study are as follows: "Community of Practice(CoP)" is the kind of community composed of "Domain", "Community" and "Practice" for knowledge circulation; The coordinator neither leader in CoP nor manager outside of CoP is necessary to sustain CoP by supporting management of CoP and promoting knowledge sharing; The programs and clubs designed by public librarians are potential CoPs; The potential CoPs turn into the sustainable CoPs when the participants of programs turn into the directors of programs; It means the coordinator of CoP is librarian in case of public libraries.