• Proceedings of the Korea Information Processing Society Conference
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• 2011.11a
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• pp.48-51
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• 2011

Universal Plug and Play (UPnP) is one of the most promising home network middleware technologies because of its straightforward implementation and zero configuration characteristics. However, it has a limitation of the operations only IP based network and proceeding in a single IP subnet. In this paper, we proposed network bridge architecture for UPnP network to interoperate heterogeneous network, UPnP and ZigBee. The proposed network bridge architecture is capable of configuration ZigBee device as a virtual UPnP device. This technique is promising for seamless inter-networking with ZigBee and UPnP network. Also, the architecture of the proposed network bridge architecture can be applied for a future smart home.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.1367-1370
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• 2008

본 논문은 P2P 네트워크 환경에서 대규모 VOD 시스템을 위한 새로운 시간 기반 캐싱 기법을 제안한다. 제안된 캐싱 기법은 각 피어들이 요구 시작 시간을 기준으로 비디오의 서로 다른 부분을 분산 저장 관리함으로써 피어의 저장 용량을 최소화하고, 피어간 데이터 요구에 대한 캐시 적중률을 향상시켜 서버의 부하를 최소화 한다. 또한 요구 시간을 기준으로 인접한 피어들을 하나의 클러스터로 그룹핑하여 피어의 탐색 법위를 최소화하고, 이에 따른 네트워크 트래픽을 최소화 한다. 시뮬레이션을 통한 성능 평가에서 피어의 참여와 탈퇴 중가에 따른 서버 부하의 증가가 기존의 P2VOD와 비교하여 크게 감소함을 보인다.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.3
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• pp.189-195
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• 2013

Amyloid-${\beta}$ peptide ($A{\beta}$), generated by proteolytic cleavage of the amyloid precursor protein (APP), plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). The key step in the generation of $A{\beta}$ is cleavage of APP by beta-site APP-cleaving enzyme 1 (BACE1). Levels of BACE1 are increased in vulnerable regions of the AD brain, but the underlying mechanism is unknown. In the present study, we reported the effects of ferrous ions at subtoxic concentrations on the mRNA levels of BACE1 and a-disintegrin-and-metalloproteinase 10 (ADAM10) in PC12 cells and the cell responses to ferrous ions. The cell survival in PC12 cells significantly decreased with 0 to 0.3 mM $FeCl_2$, with 0.6 mM $FeCl_2$ treatment resulting in significant reductions by about 75%. 4,6-diamidino-2-phenylindole (DAPI) staining showed that the nuclei appeared fragmented in 0.2 and 0.3 mM $FeCl_2$. APP-${\alpha}$-carboxyl terminal fragment (APP-${\alpha}$-CTF) associations with ADAM10 and APP-${\beta}$-CTF with BACE1 were increased. Levels of ADAM10 and BACE1 mRNA increased in response to the concentrations of 0.25 mM, respectively. In addition, p-ERK and p-Bad (S112, S155) expressions were increased, suggesting that APP-CTF formation is related to ADAM10/ BACE1 expression. Levels of Bcl-2 protein were increased, but significant changes were not observed in the expression of Bax. These data suggest that ion-induced enhanced expression of AMDA10/BACE1 could be one of the causes for APP-${\alpha}/{\beta}$-CTF activation.

• Journal of Acupuncture Research
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• v.22 no.2
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• pp.55-70
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• 2005

Objective: Ulmus davidiana Planch (Ulmaceae) has long been known to have anti-inflammnatory in the traditional Korean medicine. UD has been reported as a good enhancer for bone healing. Methods : In this experiment, we investigate the Inhibitory effects of UD on bone resorption using the bone cells culture. Different concentrations of crude extract of UD were added to mouse bone cells culture. The mitochondria activity of the bone cells after exposure was determined by colorimetric MIT assay. It was demonstrated that UD has potential effects on bone cells culture without any cytotoxicity. The most effective concentration of UD on bone cells were $100\;{\mu}g/ml$. Cathepsin K (Cat K) is the major cysteine protease expressed in osteoclasts and is thought to play a key role in matrix degradation during bone resorption. Results : When mouse long bone cells including osteoclasts and osteoblast were treated with the PI3-Kinase inhibitor, wortmannin (WT), WT prevented the osteoclast-mediated intracellular processing of Cat K. Similarly, treatment of osteoclasts-containing long bone cells with UD extracts prevented the intracellular maturation of Cat K, suggesting that UD may disrupt the intracellular trafficking of pro Cat K. This is similar to that of WT. Since secreted proenzymes have the potential to reenter the cell via mannose-6-phosphate (M6P) receptor, to prevent this possibility, we tested WT and UD in the absence or presence of M6P. Inhibition of Cat K processing by WT or UD was observed in a dose-dependent manner. Furthermore, the addition of M6P resulted in enhanced potency of WT and UD. Conclusion : UD dose-dependently inhibited in vitro bone resorption with a potency similar to that observed for inhibition of Cat K processing.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.10a
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• pp.21-24
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• 2003

In general, to enhance physical properties of PET-layered silicate nanocomposites $(P_{et}LSNs)$, it has been well known that the organic modifiers should introduce into gallery regions. However, the organic modifiers in$(P_{et}LSNs)$ may result in thermal decomposition by melt processing at high temperature, and it necessarily lead to deteriorate various physical properties of final products. Therefore, in this study, $(P_{et}LSNs)$ excluding and including organic modifiers were prepared by solution method $(S-P_{et}LSNs_{eom} and S-P_{et}LSNs_{iom})$ and we (focused on the effects of the organic modifiers in $P_{et}$ LSNs with exfoliation structure on the crystallization behaviors, the optical transparency, the thermal stability and the mechanical property. The absence and existence of organic modifiers in $S-P_{et}LSNs_{eom} and S-P_{et}LSNs_{iom}$ were investigated by EA and TGA, and nano-structure of silicate layers in $S-P_{et}LSNs$ was evaluated by using WXRD, SAXS and TEM. $S-P_{et}LSNs_{eom} and S-P_{et}LSNs_{iom}$ were mixed with neat PET as masterbatches by melt method $(M-P_{et}LSNs_{eom} and M-P_{et}LSNs_{iom})$, and also neat PET was mixed with organically modified layered silicates (OLS) by conventional direct melt method $(D-P_{et}LSNs) at 270^{\circ}C$. As results, it was found that $M-P_{et}LSNs_{eom}, M-P_{et}LSNs_{iom}, and D-P_{et}LSN$ showed a exfoliated structure and exhibited faster crystallization rate, better thermal stability and mechanical property than those of neat PET due to the dispersed and detaminated silicate layers in PET matrix. Whereas, considering organic modifiers effect, $M-P_{et}LSNs_{eom} and D-P_{et}LSN$ exhibited slower crystallization rate, poorer optical, thermal and mechanical properties, in comparison to $M-P_{et}LSNs_{eom}> due to the thermal decomposition of organic modifier in $D-P_{et}LSNs$ during melt method.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.447-450
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• 2011

This paper shows the application of P-N Learning [4] method in the soccer ball detection and improvement for increasing the speed of processing. In the P-N learning, the learning process is guided by positive (P) and negative (N) constraints which restrict the labeling of the unlabeled data, identify examples that have been classified in contradiction with structural constraints and augment the training set with the corrected samples in an iterative process. But for the long-view in the soccer game, P-N learning will produce so many ferns that more time is spent than other methods. We propose that color histogram of each frame is constructed to delete the unnecessary details in order to decreasing the number of feature points. We use the mask to eliminate the gallery region and Line Hough Transform to remove the line and adjust the P-N learning's parameters to optimize accurate and speed.

• Proceedings of the Korea Information Processing Society Conference
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• 2017.11a
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• pp.1254-1257
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• 2017

LoRa는 저전력 및 장거리 작동을 위해 설계된 새로운 ISM 대역 무선 기술이며, LoRaWAN은 LoRa에서 정의된 광역 네트워크 프로토콜이다. 본 논문에서는 실제 환경에서 LoRaWAN 기술의 통신 성능을 검증하는 것을 목표로 한다. 이를 위해, 캠퍼스 내에 LoRaWAN 실험을 위한 실제 테스트 베드를 구축했다. 사용자들이 사용하는 실제 환경을 만들기 위해 통신 게이트웨이를 실내에 설치하였고, 캠퍼스의 실내외 다수 위치에서 데이터를 P2P 방식으로 게이트웨이에게 전송한다. 실험에서는 대역폭, 코딩 속도, 확산 계수 및 전송 전력을 변화시켰으며, 성능 검증을 위해 신호대잡음비와 패킷 전송률을 측정하여 결과를 분석한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.11a
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• pp.952-954
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• 2010

효율적인 파일 공유를 일차적인 목표로 하였던 P2P 프로토콜 기술은 서서히 멀티미디어 스트리밍으로 옮겨져 가고 있다. Swarming 을 이용한 P2P 스트리밍 시스템에서 비디오를 중심으로 한 채널변경 또는 재생지점 변경으로 인해 지연현상이 발생하게 되는데, P2P 시스템에서 해결해야 하는 당면 과제이다. 지연현상을 해결하기 위한 기존의 연구로는 프리페칭 전략이 있지만, 이들은 모든 사용자들의 시청패턴을 고려하지 않았다. 본 논문에서는 사용자 인터랙션과 같은 social meta-data 를 이용하여 프리페칭을 지원하는 시스템을 제안한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.11a
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• pp.207-208
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• 2009

Peer-to-Peer (P2P) network has great potential on utilizing the network while reducing the server loads. Video on Demand (VoD) has become widely used since we can watch contents we like without having to download the overall file first. The mobile users may not need high quality of video; they only need good enough quality that can be played in the limited resource of physical device and network. So does with the devices with very limited network bandwidth. These issues emerge an idea of allowing Free-Rider in the P2P VoD system, where those low performance devices will only optimize the network utilization, affecting none to the performance of main system.

• Preventive Nutrition and Food Science
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• v.10 no.4
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• pp.333-339
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• 2005

Three lactobacillus strains, two from infant feces, and one from cow's milk, were selected among 172 isolates, from multiple sources, for further study based on the antimicrobial activities against six strains of pathogenic bacteria and identified as Lactobacillus acidophilus. The strains revealed a wide scope of spectrum against pathogenic bacteria. Viable Lactobacillus acidophilus KH-l cell counts at pH 2.0 were slightly decreased to $1.42\times10^7$ CFU/mL from $4.18\times10^7$ CFU/mL, while remaining at $3.42\times10^7$ CFU/mL at pH 4.0 with the survival rate of $33.97\%\;and\;81.82\%$, respectively. At the concentration of $0.1\%$ oxgall, L acidophilus KH-l kept growing up to $3.12\times10^7$ CFU/mL with a mean growth rate constant (k) of 0.25, and cell number was slightly decreased to $1.21\times10^7$ CFU/mL (k=0.19) with $0.3\%$ oxgall, but remained at $7.6\times10^6$ CFU/mL (k=0.17) with $0.5\%$ oxgall. L. acidophilus KH-l had a $D_{60}$ value of 7.14, with viable cell numbers $1.4\times10^5$ CFU/mL after heat treatment at $60^{\circ}C$ for 30 minutes. Stability of L acidophilus KH-l at $-20^{\circ}C$ was significantly higher, when the strain was cultivated under the optimum growth temperature $(54.41\%\;and\;54.35\%)$ than at the temperature $(13.53\%)$.