• Clinical and Experimental Pediatrics
• /
• v.56 no.12
• /
• pp.505-513
• /
• 2013

Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current knowledge pinpoints immune tolerance mechanisms as indispensable for healthy immune response to allergens in daily life. It is evident that development and maintenance of allergen-specific T cell tolerance is of vital importance for a healthy immune response to allergens. Such tolerance can be gained spontaneously by dose-dependent exposures to allergens in nature or by allergen-specific immunotherapy. Allergen-specific immunotherapy induces regulatory T cells with the capacity to secrete interleukin-10 and transforming growth factor-${\beta}$, limits activation of effector cells of allergic inflammation (such as mast cells and basophils), and switches antibody isotype from IgE to the noninflammatory type IgG4. Although allergen-specific immunotherapy is the only method of tolerance induction in allergic individuals, several factors, such as long duration of treatment, compliance problems, and life-threatening side effects, have limited widespread applicability of this immunomodulatory treatment. To overcome these limitations, current research focuses on the introduction of allergens in more efficient and safer ways. Defining the endotypes and phenotypes of allergic diseases might provide the ability to select ideal patients, and novel biomarkers might ensure new custom-tailored therapy modalities.

• International Journal of High-Rise Buildings
• /
• v.2 no.1
• /
• pp.11-21
• /
• 2013

The use of concrete filling offers a practical alternative for achieving the required stability of steel Hollow Structural Section (HSS) columns under fire conditions. However, current methods for evaluating fire resistance of Concrete Filled Hollow Structural Steel (CFHSS) columns are highly conservative as they are based on an elemental approach without due consideration to structural interactions that occur in framed structural systems. To overcome this limitation, a system level fire resistance analysis was carried out by treating CFHSS columns as part of an overall structural frame. In this analysis, an eight story steel-framed building was modeled under a range of standard and performance-based fire scenarios (including multi-story progressive burn-out fires) to evaluate the contribution of various structural members/assemblies to overall fire resistance. One of the primary factors considered was the use of concrete filling in HSS columns as an alternative to standard W-shape columns. Results from the analysis indicate that the use of CFHSS columns, in place of W-shape columns, in a performance-based environment can fully eliminate the need for applied fire protection to columns, while providing the required level of structural fire resistance.

• IEMEK Journal of Embedded Systems and Applications
• /
• v.15 no.1
• /
• pp.25-33
• /
• 2020

Multipath routing protocols with unmanned aerial vehicles have been proposed to improve reliability in tactical ad hoc networks. Most of existing studies tend to establish the paths with multiple metrics. However, these approaches suffer from link loss and congestion problems according to the network condition because they apply same metric for both ground and air path or employ the simple weight value to combine multiple metrics. To overcome this limitation, in this study, we propose new routing metrics for path over unmanned aerial vehicles and use the multi-criteria decision making (MCDM) method to determine the weight factors between multiple metrics. For the case studies, we extend the ad-hoc on-demand distance vector protocol and propose a strategy for modifying the route discovery and route recovery procedure. The simulation results show that the proposed mechanism is able to achieve high end-to-end reliability and low end-to-end delay in tactical ad hoc networks.

• Journal of ILASS-Korea
• /
• v.20 no.2
• /
• pp.107-113
• /
• 2015

To date, the demand for Combined Cycle Power Plant (CCPP) has been continuously increased to overcome the problem of air pollution and lack of energy. In particular, the underground CCPP is exposed to substantial fire and explosion risks induced by gas leakage. The present study conducted numerical simulations to examine the fire behavior and gas leakage characteristics for a restricted region including gas turbine and other components used in a typical CCPP system. The commercial code of FLUENT V.14 was used for simulation. From the results, it was found that flammable limit distribution of leakage gas affects fire behavior. Especially, the flame is propagated in an instant in restricted region with LNG gas. In addition, consequence analysis factors such as critical temperature and radiation heat flux are introduced. These results would be useful in making the safety guidelines for the underground CCPP.

• Korean Journal of Agricultural Science
• /
• v.45 no.3
• /
• pp.521-532
• /
• 2018

In recent decades, the dry stream phenomena of small and medium sized rivers have been attracting much attention as an important social problem. To prevent dry stream phenomena, it is necessary to build an infrastructure that manages rivers. To accurately determine the progress of dry stream phenomena, it is necessary to continuously measure the discharge and other hydrological factors for small and medium sized rivers. However, until now, the flow data for small and medium rivers in Korea has been insufficient. To overcome the lack of supporting data for supporting rational decision-making in policy and project implementation, a short- and long-term hydrological model was developed that takes into consideration hydrological changes such as the increase of the impervious area due to urban development and groundwater pumping, the construction of a large-scale sewage treatment plant, the maintenance of stream-oriented rivers, etc. In the developed model, the distributed grid is represented by three layers: Surface flow, interflow, and groundwater flow. The surface flow and intermediate flow flowed along the flow direction, and the groundwater flow was calculated by a two-dimensional groundwater analysis model such that the outflow occurred in all directions without a specific flow direction. The effects of land use and cover on evapotranspiration and infiltration and the effects of multiple landscapes can be simulated in the developed model.

• Journal of Korean Academy of Nursing
• /
• v.42 no.6
• /
• pp.907-915
• /
• 2012

Purpose: A diagnosis of breast cancer is one of the most traumatic events that threatens a woman's life, but while women adapt to and overcome these threats, they not only experience negative aspects, but also growth. The purpose of this study was to identify the many factors that affect growth, and to provide fundamental information for nursing interventions, which can help the women in their growth. Methods: The participants in this study were 131 married women patients with breast cancer, who were on medical treatment in one of two university hospitals, in Seoul and Chungnam. Data were collected for posttraumatic growth, self-esteem, cancer coping questionnaire, marital intimacy, and body image. The data were analyzed using the SPSS 19.0 program (IBM). Results: Interpersonal cancer coping, intrapersonal cancer coping (planning) and self-esteem accounted for 29.0% of posttraumatic growth. Conclusion: These findings indicate that in order to help the women's growth after the trauma of breast cancer, it is necessary to enhance their self-esteem, and to develop psycho-social nursing supportive programs.

• Culinary science and hospitality research
• /
• v.6 no.3
• /
• pp.99-118
• /
• 2000

This study attempts to identify the level of conflicts occurring between foreign and domestic chefs, and to suggest the way of controlling those conflicts in order to well manage human resources, foreign chefs. Based on the empirical research, the research findings shows that in terms of targeting and achieving objectives different level of conflicts are experienced when age, hotel type, position varies. For example. purchasing excessive foreign foods may cause undesirable stock which will lead to considerable loss. In order to overcome this problem the advantages of the chain-operated and the independent hotel's food purchasing system must be incorporated. Secondly, another conflicts arise when the architecture and system of a kitchen is different from what foreign chefs are familiar with. Kitchen architecture and system should be well-designed in terms of delivery channel, sanitation, safety, food control, banquet etc.. In developing menu, chefs often have different criteria in the scale of sweet and salt of a particular dish. Foreign chefs often blame his subordinates for not meeting his requirements without proper training or education. Finally, because of the different culture, communication as well as the lack of mutual understanding problem occur. Even though today is called global town. some chefs do not seem to open their minds to learn other developing countries' culture. In diversity management aspect, chefs need to put much effort to be aware of other countries' culture, history, political and economic situation. In prior to employing foreign chefs, the job enrollment and description must be prepared so as to minimize the conflicts, which otherwise will create poor job performance.

• Journal of the Korean Society of School Health
• /
• v.21 no.2
• /
• pp.1-11
• /
• 2008

Purpose: Few studies have attempted to explain the childhood's sociality issue in Korea. This study was conducted to investigate the association between obesity stress and sociality factors. Methods : The study subjects were 4th, 5th, and 6th grade students from the elementary schools in Kwangju, Anyang, and Hwasung city. The cross sectional study was carried out through the self-reported questionnaire survey about obesity stress, sociality, and socio-demographic characteristics. The data was analyzed by multiple regression analysis using SPSS 12.0 version. Results : Overall, the findings of this study were consistent with previous studies. The measures of obesity stress showed significant negative relationships with measures of childhood sociality. Specifically, the association between mental stress from obesity and socialization was more higher than other variables. In addition, multiple regression analysis found that the effect of mental stress from obesity on childhood sociality was more higher than the effect of stress from physical discomfort and the effort to overcome the obesity stress. Conclusion : Findings provide evidence for the notion that the measures of obesity stress is significantly associated with childhood sociality.

• Journal of Acupuncture Research
• /
• v.23 no.3
• /
• pp.67-75
• /
• 2006

Objectives : The purpose of this study is to evaluate the clinical effect of moxibustion treatment for FBSS patients by VAS. Methods : This clinical study was carried out for 51 cases with FBSS, who had been treated from January, 2003 to October, 2005, in oriental medical clinic. The patients were treated by the moxibustion during 8 weeks on the pain region of lower back or legs. We measured the effects of treatment by VAS. SPSS( Statistical Program for Social Science) for Windows was used for statistical analysis and repeated measures ANOVA was performed to gauge the improvement of VAS. Results : 1. We investigated 25 female and 26 male patients. The age distribution was from early 20's to 70's, among which 50's were most common. 2. The worsening factors are usually overwork and heavy lifting, but the main reason is unknown. 3. According to VAS, The patients with FBSS were improved by moxibustion treatment. Conclusion : Through this research, moxibustion therapy is considered to be effective and safe method for FBSS(Failed Back Surgery Syndrome). Moxibustion treatment had some problems that should be overcome such as severe pain and burning. Therefore we should pay more attention.

• Journal of the Korean BIBLIA Society for library and Information Science
• /
• v.21 no.1
• /
• pp.71-88
• /
• 2010

With the advent of the digital era, even thought the configuration and the importance of library resources have changed, still only traditional library resources of the past have been used to measure the effectiveness of university libraries. To overcome these limits, this study purposed to redefine the library resources factors for the evaluation of the library effectiveness as appropriate standards in digital library era. The survey method was used, the result follows. Budget, librarians, space, books, periodicals, e-journals, non-book materials, Web DB, e-book, computers are selected as input resources elements, while loan books, users, website visits, web DB uses are selected as output resoures elements. It could be noticeable that the elements related to the electronic resources was reidentified quiet a lot.