• 한국정보통신학회논문지
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• 제26권12호
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• pp.1838-1845
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• 2022

코로나19로 인해 대면으로 진행하는 현장 전시가 불가능한 상황이 지속되었다. 이를 계기로 가상현실/증강현실 등의 기술이 주목받고 있으며 많은 분야에서 이러한 기술들이 활용되고 있는데, 가장 신속히 비대면으로 전환된 분야 중 하나가 전시 예술 분야다. 이 연구에서는 가상현실 기술을 이용하여 가상 전시 공간을 제작하고 다양한 전시물을 가상으로 전시하는 가상 전시 콘텐츠를 제작하였다. 제작된 가상 전시는 동일한 내용의 전시물을 전시하는 현장 전시와 병행하여 개최되었다. 그리고 가상 전시는 HMD를 이용해 관객이 직접 체험해 볼 수 있는 기회도 제공하였다. 높은 현장감을 제공하기 위해 개방감 있게 가상 공간을 제작하였고, 사실적인 전시 구조와 같은 3D 객체와 텍스처를 이용하였다. 가상 전시 참여 관객들은 직접 참여하는 현장 전시와 유사한 체험을 할 수 있으며 동일한 전시 콘텐츠를 감상할 수 있다. 전시 이후에는 현장 전시와 가상 전시를 모두 참여한 관객에게 설문 조사하여 반응을 분석하였다. 설문 결과 가상전시의 유사성과 몰입감에 높은 점수를 부여하였다.

• 대한영상의학회지
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• 제84권1호
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• pp.275-279
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• 2023

과립 세포 종양은 신체의 모든 부위에서 발생할 수 있으나, 특히 두경부에서 주로 발생하는 드문 양성 연부 종양이며, 이 중 5%-8%가 유방에서 발생한다. 저자들은 드문 부위인 액와부 부유방에 발생한 과립 세포 종양 1예를 보고하고자 한다. 50세 여자에게 2개월 전부터 좌측 액와부에 만져지는 종괴가 있었다. 이학적 검사, 유방 촬영술 및 초음파 소견에서 유방의 악성 종양을 먼저 생각하였다. 조직 검사에서 양성 과립 세포 종양으로 진단되었으며 이후 광범위 국소 절제술을 시행하였다. 환자는 수술 후 2년의 추적 관찰 기간 동안 재발하지 않았다. 대부분의 과립 세포 종양은 양성이지만, 재발의 가능성 때문에 종양의 광범위한 완전 절제와 추적 관찰이 필요하다. 영상의학과 의사는 불필요한 치료를 막기 위해 유방 및 액와부 병변의 감별 진단으로 과립 세포 종양의 특징에 대해 알고 있어야 한다.

• 대한수의학회지
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• 제59권4호
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• pp.187-193
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• 2019

This study examined the relative incidence of feline cutaneous tumors according to age, breed, sex, and site predilection for these tumors. Biopsy samples were examined and diagnosed from the histopathology. Over a 72-month period, from January 2013 to December 2018, 478 feline biopsy samples were received from veterinary practitioners across the nation. Of these, 232 (48.54%) cases were skin masses. Among them, 73.71% (171/232) were neoplastic lesions and 26.29% (61/232) were non-neoplastic. Twenty-two different types of cutaneous neoplasms were diagnosed as epithelial tumors (15.79%), mesenchymal tumors (83.63%), or melanocytic tumor (0.58%). The four most common tumors were mast cell tumor (60.23%), lipoma (5.85%), basal cell carcinoma (4.68%), and fibrosarcoma (4.68%), which comprised 75.44% of all tumor cases. Cutaneous tumors were located most commonly in the head of the cat (43.27%) and in the Korean shorthaired breed (75.44%). According to this study, cutaneous tumors were the most common tumor types in feline neoplasms in Korea. The incidence of cutaneous tumors was highest in Korean shorthaired cats, the most prevalent breed in Korea. Mast cell tumors are the most common skin neoplasm in Korea and can affect very young cats.

• 한국패류학회지
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• 제26권1호
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• pp.97-105
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• 2010

제주 항 내에 서식하는 대수리 Thais clavigera를 조직학적 방법을 이용하여 1998년 3월부터 1999년 2월까지 생식소 발달과 생식주기 그리고 imposex 현상에 대해 조사하였다. 조직학적 관찰 결과, 배우자형성은 암,수 모두 10월에 처음 시작 되었고, 성숙한 알들은 주로 5월에서부터 7월 사이에 관찰되었다. 생식소단면적 지수 역시 알이 성숙하는 5월과 7월 사이 급격히 증가하였으며, 8월에 급격히 낮아져, 7월과 8월 사이에 집중적인 산란이 있었던 것으로 사료되었다. 유기주석화합물에 의한 imposex 현상의 진행 정도를 나타내는 RPSI는 월 평균 59.5-173.4%로 다른 지역에 비하여 비교적 높게 나타났으며, 이는 제주 항 내의 유기주석화합물에 의한 것으로 추정되었다.

• 아태비즈니스연구
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• 제3권1호
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• pp.39-47
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• 2012

Organizations pursue a CRM strategy for the purpose of increasing business performance and value. However, firms face a multitude of organizational challenges associated with this endeavor. To reduce their risk of failure, it is suggested that firms undertake a deep analysis of organizational readiness prior to committing to a CRM initiative. Insurance sector is no exception to this fact. There is an increased need to concentrate on the various challenges thrown open by the public insurance firms in implementing CRM. Many insurance firms have invested into customer driven CRM but research indicates varying outcomes (Schmith 2004). While it is clear that there are significant issues involved in the CRM implementation and success and environment faced by the public sector. It is clear that business should have an easier time in applying CRM systems is the strategic value for public sector. With customers demanding more service and accessibility from administrators, public sector CRM software technologies have to offer best solutions for achieving process and cost objectives (Souder 2001). With results which go far beyond improved service delivery and include sustained cost reductions, increased customer knowledge and better employee morale, CRM software implementation and post product environments offer great upside value. Although there are material differences in public sector use of CRM strategy, they share at least one glaring similarity - they have much to gain from proven CRM software technology. As business methods cross over in the public sector, many government bodies are investigating how they can adopt and adapt various CRM models (Bleyer 2003). There is a need to understand the similarities and differences in public sector CRM to foster shared knowledge, business processes and planning functions to integrate disparate technologies and software platforms and then, of course, the organizational culture to support knowledge sharing (Peters 1997). For the public sector, there are clearly identified CRM processes which have resulted in increased profits and improved efficiency. These have focused on sales, marketing and customer service activities, which often operate along fundamentally different lines in various public sector insurance companies. Thus the present research paper makes an attempt to explore how public sector CRM methods can be adopted and subsequently adapted.

• 대한후두음성언어의학회지
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• 제18권2호
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• pp.108-112
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• 2007

Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms ; and the constellation of symptoms has been called laryngopharyngeal reflux (LPR). In the absence of definite diagnostic criteria, LPR disease remains a subjective entity. A diagnosis of LPR is usually based on response of symptoms to empirical treatment. Investigative modalities such as pH monitoring and, more recently, impedance studies are generally reserved for treatment failures. LPR usually requires more aggressive and prolonged treatment to achieve regression of both symptoms and laryngeal findings. The suppression of gastric acid and secretion with anti-secretary agents has been the mainstay of medical treatment for patients with acid-related disorders. The suppression of gastric acid secretion achieved with Hz-receptor antagonist $(H_2RA)$ has proved suboptimal for relief of reflux symptoms. The rapid development of tolerance and rebound acid hypersecretion after the with-drawal of $H_2RA$ limit their clinical use. Proton pump inhibitors (PPI) have been proved to be very effective for suppressing intragastric acidity, but the optimal dose and duration is unknown. Current evidence indicates that pharmacologic intervention should include, at a minimum, a 3 month trial of twice daily PPI. Symptoms of LPR improve over 2 months of therapy. The physical findings of LPR resolve more slowly than the symptoms and this continues through out at least 6 months of treatment. For most patients with LPR, twice daily dosing with a PPI is usually recommended for an initial treatment for a period of no less than 6 months treatment, and lifetime treatment may be required.

• 한국임상약학회지
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• 제28권1호
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• pp.65-75
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• 2018

Objective: Over the last several years, immunotherapy has become one of the most promising therapeutic options for cancer. This study aims to summarize the updates on cancer immunotherapy focusing on immune checkpoint inhibitors, such as programmed cell death-1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitors, which have received attention as new anticancer therapeutic agents. Methods: A literature survey was carried out on PubMed to identify high-impact papers on cancer immunotherapy from 2010. The most recent data on clinical efficacy and safety have been included highlighting the response characteristics to recently approved immunotherapeutic agents. Results: In various cancers, immune checkpoints are a means for cancer cells to evade the immune system. Furthermore, CTLA-4 and PD-L1 can be overexpressed, allowing malignant cells to evade T-cells. Numerous clinical trials have been performed to seek appropriate indication of these products in various cancer types. Among them, the most conspicuous types are melanoma, non-small-cell lung cancer, and head and neck cancer. The approval of ipilimumab by Food and Drug Administration (FDA) commenced a new era of cancer immunotherapy. This was followed by the approval of nivolumab and pembrolizumab. Currently, combination therapies are being investigated for various cancer types. Conclusion: In this study, we reviewed recently reported scientific and clinical evidence for currently approved immune checkpoint inhibitors. Although these novel checkpoint inhibitors are ever evolving for cancer therapies, there exist limitations that need to be overcome, indicating the necessity for further studies aiming to improve their efficacy, toxicity, and cost.

• 한국응용과학기술학회지
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• 제7권1호
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• pp.13-24
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• 1990

2-N,N,N-trimethyl ammonia decanoate, 2-N,N,N-trimethyl ammonio dodecanoate, 2-N,N,N-trimethyl ammonia tetradecanoate and 2-N,N,N-hexadecanoate with in straight long chain alkyl carboxybetaines, and N-decyl N,N-dimethyl ammonio ethanoate, N-dodecyl N,N-dimethyl ammonia ethanoate, N-tetradecyl N,N-dimethyl ammonia ethanoate and N-hexadecyl N,N-dimethyl ammonia ethanoate with in nitrogen-straight long chain alkyl carboxy betaines measured respectively surface tensions by the stalagmometer method at various temperature, also their critical micelle concentration were evaluated. In micellization, the contribution of standard free energy change(${\Delta}G^{\circ}m$), standard enthalpy change(${\Delta}H^{\circ}m$) and standard entropy change (${\Delta}S^{\circ}m$), have been calculated, with increasing temperature. ${\Delta}H^{\circ}m$ changes from negative, and a similar change in the sign of ${\Delta}H^{\circ}m$ is observed with increasing chain length at $25^{\circ}C$, while the entropy of micellization, ${\Delta}S^{\circ}m$ is positive over the temperature range studied, it becomes less so at higher temperatures. Estimates of the enthalpy and entropy contribution attributable to the ion head group and alkyl chain have been made. The enthalpy and entropy change, per methylene group increase respectively with increasing chain length the result are discussed in terms of current theories of micellization.

• Asian-Australasian Journal of Animal Sciences
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• 제26권10호
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• pp.1388-1398
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• 2013

The present study investigated the contribution of carcass traits on carcass prices of Holstein steers in Korea. Phenotypic data consisted of 76,814 slaughtered Holsteins (1 to 6 yrs) from all over Korea. The means for live body weight at slaughter (BWT), chilled carcass weight (CWT), dressing percentage (DP), quantity grade index (QGI), eye muscle area (EMA), backfat thickness (BF) and marbling score (MS), carcass unit price (CUP), and carcass sell prices (CSP) were 729.0 kg, 414.2 kg, 56.79%, 64.42, $75.26cm^2$, 5.77 mm, 1.98, 8,952.80 Korean won/kg and 3,722.80 Thousand Korean won/head. Least squares means were significantly different by various age groups, season of slaughter, marbling scores and yield grades. Pearson's correlation coefficients of CUP with carcass traits ranged from 0.12 to 0.62. Besides, the relationships of carcass traits with CSP were relatively stronger than those with CUP. The multiple regression models for CUP and CSP with carcass traits accounted 39 to 63% of the total variation, respectively. Marbling score had maximum economic effects (partial coefficients) on both prices. In addition, the highest standardized partial coefficients (relative economic weights) for CUP and CSP were calculated to be on MS and CWT by 0.608 and 0.520, respectively. Path analyses showed that MS (0.376) and CWT (0.336) had maximum total effects on CUP and CSP, respectively; whereas BF contributed negatively. Further sub-group (age and season of slaughter) analyses also confirmed the overall outcomes. However, the relative economic weights and total path contributions also varied among the animal sub-groups. This study suggested the significant influences of carcass traits on carcass prices; especially MS and CWT were found to govern the carcass prices of Holstein steers in Korea.

• 한국수자원학회논문집
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• 제51권11호
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• pp.1011-1020
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• 2018

본 연구에서는 미급수지역의 주요 수원인 지하수위 현황을 이용한 가뭄 모니터링 기법을 개발하기 위해 256개의 국가지하수관측망 관측 자료를 이용하여 관측소별, 월별 수위분포를 핵밀도함수로 추정하였다. 추정된 누적분포함수를 이용하여 월별 지하수위의 분위수를 구하고, 분위수를 정규화 하여 표준지하수지수(SGI)를 산정하였다. 관측소별로 산정된 SGI는 티센망을 이용하여 167개 시군별 SGI로 변환하였다. SGI의 범위에 따른 가뭄등급을 설정하여 시군별 지하수 가뭄 정도를 모니터링 할 수 있는 기법을 제시하였다. 이를 통해 계측이 이루어지지 않는 미급수지역의 지하수가뭄상황을 국가지하수관측망을 활용해 간접적으로 판단할 수 있도록 하였다.