• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.12
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• pp.1838-1845
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• 2022

Due to COVID-19, the face-to-face on-site exhibitions were not held. With this opportunity, technologies such as virtual reality/augmented reality are increasing attention, and these technologies are being used in many fields. In this study, we made a virtual exhibition content which was produced using virtual reality technology. Our virtual exhibition was held in parallel with the on-site exhibition that included the same contents. Also this exhibition provided an opportunity to realistic experience using the head mounted display. In order to provide a high sense of presence, we created an open virtual space and used realistic 3D objects and textures. Although it is a virtual exhibition, the audience can experience a sense of realism like an on-site exhibition. After the exhibition was over, a survey was conducted on the audience who participated in both the on-site exhibition and virtual exhibition to analyze their responses. As a result of the survey, the similarity and immersion of the virtual exhibition were highly evaluated.

• Journal of the Korean Society of Radiology
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• v.84 no.1
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• pp.275-279
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• 2023

Granular cell tumors (GCTs) are rare benign soft tissue tumors that can occur throughout the body, particularly the head and neck; only 5%-8% of GCTs occur in the breast. We report a case of a GCT of the axillary accessory breast, which is a rare location of this tumor. A 50-year-old woman had a 2-month history of a palpable mass in the left axilla. Physical examination, as well as mammographic and ultrasonographic findings suggested a breast malignancy. Histopathological examination showed a benign GCT, and wide local excision was performed. The patient has remained disease-free over 2 years postoperatively. Although most GCTs are benign, wide complete resection of the tumor and follow-up are required considering the possibility of recurrence. The radiologist should know the characteristics of GCTs as a differential diagnosis of breast and axillary lesions to prevent unnecessary treatment.

• Korean Journal of Veterinary Research
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• v.59 no.4
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• pp.187-193
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• 2019

This study examined the relative incidence of feline cutaneous tumors according to age, breed, sex, and site predilection for these tumors. Biopsy samples were examined and diagnosed from the histopathology. Over a 72-month period, from January 2013 to December 2018, 478 feline biopsy samples were received from veterinary practitioners across the nation. Of these, 232 (48.54%) cases were skin masses. Among them, 73.71% (171/232) were neoplastic lesions and 26.29% (61/232) were non-neoplastic. Twenty-two different types of cutaneous neoplasms were diagnosed as epithelial tumors (15.79%), mesenchymal tumors (83.63%), or melanocytic tumor (0.58%). The four most common tumors were mast cell tumor (60.23%), lipoma (5.85%), basal cell carcinoma (4.68%), and fibrosarcoma (4.68%), which comprised 75.44% of all tumor cases. Cutaneous tumors were located most commonly in the head of the cat (43.27%) and in the Korean shorthaired breed (75.44%). According to this study, cutaneous tumors were the most common tumor types in feline neoplasms in Korea. The incidence of cutaneous tumors was highest in Korean shorthaired cats, the most prevalent breed in Korea. Mast cell tumors are the most common skin neoplasm in Korea and can affect very young cats.

• The Korean Journal of Malacology
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• v.26 no.1
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• pp.97-105
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• 2010

Annual gonad development of the rock shell, Thais clavigera distributed in Jeju Port was investigated over a 12 month period from March 1998 to February 1999. Monthly change in gonad development was examined using histology. Gametogenesis of T. clavigera in the study area initiated as early as in October and fully ripe eggs could be observed from May to July. Percent gonad area (PGA) also increased rapidly from May to July then dropped in August when the water temperature remained $22.6-24.5^{\circ}C$, suggesting that rock shell released their eggs during this period. All female rock shell collected during the course of study exhibited pseudo-penis in the head, indicating that a certain level of imposex had progressed in the study site. Relative penis size index (RPSI), an indicator of level of imposex phenomenon varied 59.5-173.4% and this value was relatively higher than the index reported from elsewhere. It was believed that such imposex phenomenon observed in T. clavigera was caused by endocrine disruption by chemical contaminants such as TBTs released from biocidal paints in the port environment.

• Asia-Pacific Journal of Business
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• v.3 no.1
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• pp.39-47
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• 2012

Organizations pursue a CRM strategy for the purpose of increasing business performance and value. However, firms face a multitude of organizational challenges associated with this endeavor. To reduce their risk of failure, it is suggested that firms undertake a deep analysis of organizational readiness prior to committing to a CRM initiative. Insurance sector is no exception to this fact. There is an increased need to concentrate on the various challenges thrown open by the public insurance firms in implementing CRM. Many insurance firms have invested into customer driven CRM but research indicates varying outcomes (Schmith 2004). While it is clear that there are significant issues involved in the CRM implementation and success and environment faced by the public sector. It is clear that business should have an easier time in applying CRM systems is the strategic value for public sector. With customers demanding more service and accessibility from administrators, public sector CRM software technologies have to offer best solutions for achieving process and cost objectives (Souder 2001). With results which go far beyond improved service delivery and include sustained cost reductions, increased customer knowledge and better employee morale, CRM software implementation and post product environments offer great upside value. Although there are material differences in public sector use of CRM strategy, they share at least one glaring similarity - they have much to gain from proven CRM software technology. As business methods cross over in the public sector, many government bodies are investigating how they can adopt and adapt various CRM models (Bleyer 2003). There is a need to understand the similarities and differences in public sector CRM to foster shared knowledge, business processes and planning functions to integrate disparate technologies and software platforms and then, of course, the organizational culture to support knowledge sharing (Peters 1997). For the public sector, there are clearly identified CRM processes which have resulted in increased profits and improved efficiency. These have focused on sales, marketing and customer service activities, which often operate along fundamentally different lines in various public sector insurance companies. Thus the present research paper makes an attempt to explore how public sector CRM methods can be adopted and subsequently adapted.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.18 no.2
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• pp.108-112
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• 2007

Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms ; and the constellation of symptoms has been called laryngopharyngeal reflux (LPR). In the absence of definite diagnostic criteria, LPR disease remains a subjective entity. A diagnosis of LPR is usually based on response of symptoms to empirical treatment. Investigative modalities such as pH monitoring and, more recently, impedance studies are generally reserved for treatment failures. LPR usually requires more aggressive and prolonged treatment to achieve regression of both symptoms and laryngeal findings. The suppression of gastric acid and secretion with anti-secretary agents has been the mainstay of medical treatment for patients with acid-related disorders. The suppression of gastric acid secretion achieved with Hz-receptor antagonist $(H_2RA)$ has proved suboptimal for relief of reflux symptoms. The rapid development of tolerance and rebound acid hypersecretion after the with-drawal of $H_2RA$ limit their clinical use. Proton pump inhibitors (PPI) have been proved to be very effective for suppressing intragastric acidity, but the optimal dose and duration is unknown. Current evidence indicates that pharmacologic intervention should include, at a minimum, a 3 month trial of twice daily PPI. Symptoms of LPR improve over 2 months of therapy. The physical findings of LPR resolve more slowly than the symptoms and this continues through out at least 6 months of treatment. For most patients with LPR, twice daily dosing with a PPI is usually recommended for an initial treatment for a period of no less than 6 months treatment, and lifetime treatment may be required.

• Korean Journal of Clinical Pharmacy
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• v.28 no.1
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• pp.65-75
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• 2018

Objective: Over the last several years, immunotherapy has become one of the most promising therapeutic options for cancer. This study aims to summarize the updates on cancer immunotherapy focusing on immune checkpoint inhibitors, such as programmed cell death-1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitors, which have received attention as new anticancer therapeutic agents. Methods: A literature survey was carried out on PubMed to identify high-impact papers on cancer immunotherapy from 2010. The most recent data on clinical efficacy and safety have been included highlighting the response characteristics to recently approved immunotherapeutic agents. Results: In various cancers, immune checkpoints are a means for cancer cells to evade the immune system. Furthermore, CTLA-4 and PD-L1 can be overexpressed, allowing malignant cells to evade T-cells. Numerous clinical trials have been performed to seek appropriate indication of these products in various cancer types. Among them, the most conspicuous types are melanoma, non-small-cell lung cancer, and head and neck cancer. The approval of ipilimumab by Food and Drug Administration (FDA) commenced a new era of cancer immunotherapy. This was followed by the approval of nivolumab and pembrolizumab. Currently, combination therapies are being investigated for various cancer types. Conclusion: In this study, we reviewed recently reported scientific and clinical evidence for currently approved immune checkpoint inhibitors. Although these novel checkpoint inhibitors are ever evolving for cancer therapies, there exist limitations that need to be overcome, indicating the necessity for further studies aiming to improve their efficacy, toxicity, and cost.

• Journal of the Korean Applied Science and Technology
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• v.7 no.1
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• pp.13-24
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• 1990

2-N,N,N-trimethyl ammonia decanoate, 2-N,N,N-trimethyl ammonio dodecanoate, 2-N,N,N-trimethyl ammonia tetradecanoate and 2-N,N,N-hexadecanoate with in straight long chain alkyl carboxybetaines, and N-decyl N,N-dimethyl ammonio ethanoate, N-dodecyl N,N-dimethyl ammonia ethanoate, N-tetradecyl N,N-dimethyl ammonia ethanoate and N-hexadecyl N,N-dimethyl ammonia ethanoate with in nitrogen-straight long chain alkyl carboxy betaines measured respectively surface tensions by the stalagmometer method at various temperature, also their critical micelle concentration were evaluated. In micellization, the contribution of standard free energy change(${\Delta}G^{\circ}m$), standard enthalpy change(${\Delta}H^{\circ}m$) and standard entropy change (${\Delta}S^{\circ}m$), have been calculated, with increasing temperature. ${\Delta}H^{\circ}m$ changes from negative, and a similar change in the sign of ${\Delta}H^{\circ}m$ is observed with increasing chain length at $25^{\circ}C$, while the entropy of micellization, ${\Delta}S^{\circ}m$ is positive over the temperature range studied, it becomes less so at higher temperatures. Estimates of the enthalpy and entropy contribution attributable to the ion head group and alkyl chain have been made. The enthalpy and entropy change, per methylene group increase respectively with increasing chain length the result are discussed in terms of current theories of micellization.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.10
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• pp.1388-1398
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• 2013

The present study investigated the contribution of carcass traits on carcass prices of Holstein steers in Korea. Phenotypic data consisted of 76,814 slaughtered Holsteins (1 to 6 yrs) from all over Korea. The means for live body weight at slaughter (BWT), chilled carcass weight (CWT), dressing percentage (DP), quantity grade index (QGI), eye muscle area (EMA), backfat thickness (BF) and marbling score (MS), carcass unit price (CUP), and carcass sell prices (CSP) were 729.0 kg, 414.2 kg, 56.79%, 64.42, $75.26cm^2$, 5.77 mm, 1.98, 8,952.80 Korean won/kg and 3,722.80 Thousand Korean won/head. Least squares means were significantly different by various age groups, season of slaughter, marbling scores and yield grades. Pearson's correlation coefficients of CUP with carcass traits ranged from 0.12 to 0.62. Besides, the relationships of carcass traits with CSP were relatively stronger than those with CUP. The multiple regression models for CUP and CSP with carcass traits accounted 39 to 63% of the total variation, respectively. Marbling score had maximum economic effects (partial coefficients) on both prices. In addition, the highest standardized partial coefficients (relative economic weights) for CUP and CSP were calculated to be on MS and CWT by 0.608 and 0.520, respectively. Path analyses showed that MS (0.376) and CWT (0.336) had maximum total effects on CUP and CSP, respectively; whereas BF contributed negatively. Further sub-group (age and season of slaughter) analyses also confirmed the overall outcomes. However, the relative economic weights and total path contributions also varied among the animal sub-groups. This study suggested the significant influences of carcass traits on carcass prices; especially MS and CWT were found to govern the carcass prices of Holstein steers in Korea.

• Journal of Korea Water Resources Association
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• v.51 no.11
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• pp.1011-1020
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• 2018

This study aims to develop a drought monitoring scheme based on groundwater which can be exploit for water supply under drought stress. In this context, groundwater level can be used as a proxy for better understanding the temporal evolution of drought state. First, kernel density estimator is presented in the monthly groundwater level over the entire national groundwater stations. The estimated cumulative distribution function is then utilized to map the monthly groundwater level into the standardized groundwater level index (SGI). The SGI for each station was eventually converted into the index for major cities through the Thiessen polygon approach. We provide a drought classification for a given SGI to better characterize the degree of drought condition. Ultimately, we conclude that the proposed monitoring framework enables a more reliable estimation of the drought stress, especially for a limited water supply area.