• Title/Summary/Keyword: Over-Sampling

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Diagnostic Accuracy of Cervicovaginal Cytology in the Detection of Squamous Epithelial Lesions of the Uterine Cervix; Cytologic/Histologic Correlation of 481 Cases (자궁경부 편평상피병변에서 자궁경부질도말 세포검사의 진단정확도 : 481예의 세포-조직 상관관계)

  • Jin, So-Young;Park, Sang-Mo;Kim, Mee-Sun;Jeen, Yoon-Mi;Kim, Dong-Won;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • 제19권2호
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    • pp.111-118
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    • 2008
  • Background : Cervicovaginal cytology is a screening test of uterine cervical cancer. The sensitivity of cervicovaginal cytology is less than 50%, but studies of cytologic/histologic correlation are limited. We analyzed the diagnostic accuracy of cervicovaginal cytology in the detection of the squamous epithelial lesions of the uterine cervix and investigate the cause of diagnostic discordance. Materials and Methods : We collected a total of 481 sets of cervicovaginal cytology and biopsies over 5 years. The cytologic diagnoses were categorized based on The Bethesda System and the histologic diagnoses were classified as negative, flat condyloma, cervical intraepithelial neoplasia (CIN) I, CIN II, CIN III, or squamous cell carcinoma. Cytohistologic discrepancies were reviewed. Results: The concordance rate between the cytological and the histological diagnosis was 79.0%. The sensitivity and specificity of cervicovaginal cytology were 80.6% and 92.6%, respectively. Its positive predictive value and negative predictive value were 93.7% and 77.7%, respectively. The false negative rate was 19.4%. Among 54 false negative cytology cases, they were confirmed by histology as 50 flat condylomas, 2 CIN I, 1 CIN III, and 1 squamous cell carcinoma. The causes of false negative cytology were sampling errors in 75.6% and interpretation errors in 24.4%. The false positive rate was 7.4%. Among 15 false positive cytology cases, they were confirmed by histology as 12 atypical squamous cells of undetermined significance (ASCUS) and 3 low grade squamous intraepithelial lesions (LSIL). The cause of error was interpretation error in all cases. The overall diagnostic accuracy of cervicovaginal cytology was 85.7%. Conclusions : Cervicovaginal cytology shows high overall diagnostic accuracy and is a useful primary screen of uterine cervical cancer.

Water Quality in Hwawon Coastal Sea of Korea for Rainy and Dry Season (건기와 우기시 화원면 주변 해역의 수질 비교)

  • Kim, Do-Hee
    • Journal of the Korean Society for Marine Environment & Energy
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    • 제10권4호
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    • pp.193-200
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    • 2007
  • The purpose of this study is investigate to water quality, pH, turbidity, salinity, nutrients, SS, DO, COD, ${NH_4}^+$-N, ${NO_2}^-+{NO_3}^-$-N, TN, TP, ${PO_4}^{3-}$-P in ditches and seawater of the Hwawon, southwestern coastal area of Korea. Two stations of the ditch, one station at outfall from reservoir of the coastal development and 15 stations of seawater were measured in August just after a 96.5 mm rainfall and in dry season of November 2006. The sampling time were divided into a rainy and dry season based on turbidity, SS, salinity and nutrients difference of distributions that was evidence as a inflow of pollutants from the developing coastal land area. The pH, turbidity, salinity and SS were high and showed different from between surface and bottom in near the developing of coastal land than the other stations after a strong rainfall over 90 mm while it were not varied in vertical and horizontal concentration profile in dry season. The other nutrients were showed the same concentrations gradient patterns. In opposition to expectations, the SS in dry season was higher than in the rainy season due to upwelling by the wind and strong current. It appears that the researched coastal seawater qualities were mainly effected by the inflow of freshwater from the ditches and drain from the reservoir of the developing land area during strong rainfall while the seawater qualities were mainly effected by the wind and strong current in dry season.

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Studies on the Quantitative analysis and the Health Effect of VOCs in Environment - Analysis for THMs of tap water in six cities of Korea - (VOCs 측정 및 VOCs가 인체에 미치는 영향에 관한 연구 - 우리나라 6개 대도시 수도수 중 THMs 분석 -)

  • Kim, Mi-Kyoung;Park, Yuon-Sin;Chung, Yong
    • Analytical Science and Technology
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    • 제13권1호
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    • pp.55-65
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    • 2000
  • In this study, we collected the tap water that treated from water plant in Seoul, Incheon, Taejon, Kwangju, Taeku and Pusan and supplied each house. The sampling period was June and September, 1997. The concentration of THMs formed by chlorination in drinking water was determined with the purge and trap method with GC/MSD recommended by the us EPA 542.2 method. Chloroform is the most of THMs (47.43%~93.11%) and the content order is bromodichloromethane > chlorodibromomethane > bromoform. In Incheon, Taejon, Kwangju, Taeku and Pusan, the content of bromodichloromethane, chlorodibromomethane and bromoform was higher than Seoul. But, in June and September, the concentration of THMs in six cities is not over Korea Drinking Water Regulation $100{\mu}g/L$. The calculated human exposure for each substances were chloroform $6.14{\times}10^{-4}mg/kg/day$, bromodichloromethane $1.01{\times}10^{-4}mg/kg/day$, chlorodibromomethane $0.29{\times}10^{-4}mg/kg/day$, bromoform $0.01{\times}10^{-4}mg/kg/day$ and THMs $7.98{\times}10^{-4}mg/kg/day$.

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Mobility of pesticides in different soil textures and gravel contents under soil column (토양 column을 이용한 토성 및 자갈함량별 농약 이동특성)

  • Lee, Sang-Min;Kim, Seong-Soo;Park, Dong-Sik;Hur, Jang-Hyun
    • The Korean Journal of Pesticide Science
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    • 제9권4호
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    • pp.330-337
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    • 2005
  • This study was investigated to elucidate the pesticide mobility in three different soil textures(Heongseong sandy loam; Chuncheon, loam; Taeback, silty clay loam) and four different gravel contents(0, 20, 40, 60%) of Taebaek soil using soil column. Carbofuran, which ranks the highest water solubility among 7 pesticides(carbendazim, carbofuran, chlorpyrifos, cypermethrin, dimethomorph, diniconazole and endosulfan) was defected over 87% in leachate samples within all soil types from early sampling time. Amount of 5 residual pesticides excluding carbendazim and carbofuran were ordered silty clay loam > loam > sandy loam, indicating pesticide residues are related to percentage of clay contents in soils. Comparing the amount of residual pesticides in soil column(upper, middle and lower layer), 6 pesticides apart from carbofuran were found in the range of $50{\sim}92%$ on the upper layer of silty clay loam and loam. Mobility of pesticides either in soil or leachate samples is dependant on water solubility of pesticide and clay content of soil. The results obtained from four different gravel contents of Tacback soil were similar to the results of three different soil textures. Also it was found that more the gravel contents, faster the flow velocity of leachate water. These results possibly provide an idea to select proper pesticides and to reduce soil and water contamination at alpine and sloped-land.

Relationship between Organizational Culture, Organizational Trust and Organizational Performance of Special Guard Organization (특수경비조직의 조직문화와 조직신뢰 및 조직성과의 관계)

  • Kim, Hyo-Joon
    • Korean Security Journal
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    • 제29호
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    • pp.59-86
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    • 2011
  • The purpose of this study is to investigate the relationship between organizational culture, organizational trust and organizational performance of special guard organization. This study had selected special guards from 4 different private guard companies which are in Seoul area on March 2011. Using Judgement Sampling, 161 samples were drawn for the use of final analysis. Questionnaire used in this study was consisted of the total 42 question, and executed frequency analysis, factor analysis, reliability analysis, correlation analysis, multiple regression analysis, path analysis by SPSSWIN 18.0. The Cronbach's ${\alpha}$ value which represents the reliability of the survey came out to be over .592. The results are following: First, the organizational culture of special guard organization affects organizational trust. That is, when a developmental, reasonable, consensual and hierarchical culture is activated, cognitive emotional and behavioral trust is increased. Second, organizational culture of special guard organization affects organizational performance. That is, when a reasonable and consensual culture is activated, job-satisfaction becomes higher. On the other hand, when a developmental, reasonable and hierarchical culture is activated, organizational flow becomes higher. Third, organizational trust of special guard organization affects organizational performance. That is, when a cognitive emotional and behavioral trust works highly, job-satisfaction and organizational flow is increased. Fourth, Special security organization's organizational culture affects as a result in organization result. As well as organizational culture exerts direct influence on organization outcome, I exert effect that is indirect in organization outcome through action trust which is low rank factor of organization trust.

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Cancer patients' need for financial assistance and its related factors (암 환자가 느끼는 경제적 도움에 대한 필요와 이에 영향을 미치는 요인)

  • Kim, Youn-Gu;Park, Jae-Hyun;Park, Jong-Hyock
    • Health Policy and Management
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    • 제20권4호
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    • pp.58-73
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    • 2010
  • Background : Cancer is a disease that not only places a significant burden on patients clinically but also requires significant expense for diagnosis and treatment. Although the cancer coverage of health insurance has recently been expended, the need for financial assistance among cancer patients and their families is still expected to be significant. In this study, cancer patients' need for financial assistance in Korea was examined and its influence factors were analyzed. Methods : Target study subjects were those who are over 18 years of age and were diagnosed with cancer more than four months prior at the National Cancer Center and 9 Regional Cancer Centers in Korea during the period from July to August of 2008. Quarter sampling was conducted according to the ratio of the type of each cancer. A face to face interview survey was conducted. A total of 2,661 cancer patients finished the survey. Medical charts were reviewed in order to obtain the cancer type and SEER stage of cancer patients. An ordered logistic regression model was used to examine the level of need for financial assistance according to the demographical, clinical, and socio-economic variables of cancer patients. Result : The percentage of cancer patients who needed financial assistance was 69.0%, and 36.9% needed significant financial assistance. The need for financial assistance was perceived to be greater in males, younger age group, low income group, low education group, medical aid recipients, those who were diagnosed recently, those with a low level of quality of life measured through EQ5D, and those with decreased income after cancer diagnosis. Conclusion : In spite of the current policy to increase health insurance coverage, the majority of cancer patients and their families in Korea still need financial assistance due to cancer. In particular, there were more vulnerable groups, such as the low income, or low education group. In the future, policies that focus on the disadvantaged, which strengthen social security, should be considered for achievement of a substantially better quality of life for cancer patients and their families.

Test turnaround Time for Complete Blood Cell Count using Delta and Panic Value Checks and the Q-flag Limit

  • Koo, Bon-Kyung;Ryu, Kwang-Hyun;Lim, Dae-Jin;Cho, Young-Kuk;Kim, Hee-Jin
    • Korean Journal of Clinical Laboratory Science
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    • 제44권2호
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    • pp.66-74
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    • 2012
  • Test turnaround time (TAT) is the lead time from reception to reporting. In the complete blood cell count (CBC), 4 units of the XE-2100 (Sysmex Corp., Japan) processed around 80% of quantity, 1 unit of the LH-780 (Beckman-Coulter Incorp., USA) processed around 10% and 1 unit of ADVIA-2120 (Siemens AG, Munich, Germany) processed around 10%. We analyzed the change in the TAT for the CBC for over 7 years, from January of 2005 to December of 2011. The delta check made alterations of delta to WBC, hemoglobin, hematocrit, platelet and metamyelocyte, however, did not made them to band neutrophil, eosinophil, basophil and monocyte. The panic value check made alterations of panic value to hemoglobin, hematocrit, platelet and monocyte. In the criteria of currently slide review, LH-780 and ADVI-2120 analyzers prepared suspect flags of "Blast, Imm NE2, Immature granulocyte, Imm NE1, Left shift, Variant lymphocyte, Atypical lymphocyte, Platelet clumps and NRBC". The New slide review in the XE-2100 analyzer altered the preparations of a smear slide more than a "Platelet clumps flag(${\geq}200unit$), a single flag excluding the "Platelet clumps flag (${\geq}250unit$) and a multiple flag (${\geq}200unit$)". Also, below the 240 unit, medical technologists prepared manual slides selectively according to their evaluations. The automatic reporting rate was 33.4% without alterations, whereas it was 41.0% without alterations, and was thus improved by 7.6%. The slide review rate was 15.2% before using the Q-flag limit, whereas it was 12.1% for a reduce 3.1%. TAT was 45 minutes without the creation alterations of the delta and panic value checks, whereas it was 35 minutes after making alterations of the delta and panic value checks and thus was shortened by 10 minutes. We came to the conclusion that the establishment and operation of delta and panic value checks and slide review criteria suitable for laboratory environment can reduce unnecessary smear slides, re-checking, re-sampling, re-testing, telephone inquiries and concentrated workloads during specific times of the day.

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A Study on the Awareness of medical and Health-Related Majors on Drinking Culture (의·보건 계열 대학생의 음주문화 인식에 관한 연구)

  • Kim, Kwang-Hwan;Han, Jin-Sook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • 제12권11호
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    • pp.5043-5048
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    • 2011
  • The purpose of this study was to examine the drinking awareness of medical and health-related majors in a bid to find out the impact of their drinking awareness on drinking. The subjects in this study were 153 students who were selected by rendem sampling from colleges located in two different cities in the province. Data collection was performed from may 1 to september 20, 2011 with total 153 college students. Out of them, 86 students majored in medical departments, and 67 students were in the health-related departments. After a self-administered survey was conducted, the following findings were given: A great deal of the students who accounted for 75.8 percent were ever disturbed in daily routine life by drinking over the past year. As for the influence of drinking awareness on the amount of drinking, the amount of drinking was under the significant influence of the following five items. The first was that alcohol was an energizer(p<.001), and the second was that drinking led to a sound sleep(p<.01). The third was that I drank too much with my close friends often(p<.05), and the fourth was that alcohol used as a hangover-chaser was conducive to a hangover(p<.05). The fifth was that alcohol had the largest impact on the liver(p<.05). All the variables made a 43.4% prediction of the amount of drinking. In conclusion, the medical and health-related majors who learned about the impact of drinking on the human body in a firsthand or secondhand manner had a tendency to drink a less amount of alcohol and do less binge drinking. It's advisable to take advantage of the knowledge of medical and health-related majors on the human body and drinking as resources of anti-drinking education.

Estimation of Classification Accuracy of JERS-1 Satellite Imagery according to the Acquisition Method and Size of Training Reference Data (훈련지역의 취득방법 및 규모에 따른 JERS-1위성영상의 토지피복분류 정확도 평가)

  • Ha, Sung-Ryong;Kyoung, Chon-Ku;Park, Sang-Young;Park, Dae-Hee
    • Journal of the Korean Association of Geographic Information Studies
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    • 제5권1호
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    • pp.27-37
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    • 2002
  • The classification accuracy of land cover has been considered as one of the major issues to estimate pollution loads generated from diffuse landuse patterns in a watershed. This research aimed to assess the effects of the acquisition methods and sampling size of training reference data on the classification accuracy of land cover using an imagery acquired by optical sensor(OPS) on JERS-1. Two kinds of data acquisition methods were considered to prepare training data. The first was to assign a certain land cover type to a specific pixel based on the researchers subjective discriminating capacity about current land use and the second was attributed to an aerial photograph incorporated with digital maps with GIS. Three different sizes of samples, 0.3%, 0.5%, and 1.0% of all pixels, were applied to examine the consistency of the classified land cover with the training data of corresponding pixels. Maximum likelihood scheme was applied to classify the land use patterns of JERS-1 imagery. Classification run applying an aerial photograph achieved 18 % higher consistency with the training data than the run applying the researchers subjective discriminating capacity. Regarding the sample size, it was proposed that the size of training area should be selected at least over 1% of all of the pixels in the study area in order to obtain the accuracy with 95% for JERS-1 satellite imagery on a typical small-to-medium-size urbanized area.

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Development of the Korean Form of Zung's Self-Rating Depression Scale (한국형 자가평가 우울척도의 개발)

  • Lee, Jung-Hoon
    • Journal of Yeungnam Medical Science
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    • 제12권2호
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    • pp.292-305
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    • 1995
  • This study was carried out to develop a Korean language version of Zung's self-rating depression scale (SDS). The subjects consisted of 173 males and 161 females drawn from various groups of the general population by a cluster of sampling methods. In order to analyze the data on depression scores, Pearson's product moment correlation coefficient method was carried out, as well as reliability and factor analysis, by the SPSS/PC+ program. The results obtained were as follows: The mean average of the total depression scores were $40.60{\pm}8.66$ for the subjects. Thirty-seven subjects (11.1%) showed high depression scores of 50 or over. Test-retest reliability(coefficient r=0.82, p <0.001), internal consistency(coefficient r=0.84, p <0.001) were satisfactory. Factor analysis using oblique technique rotation yielded five factors. The items of confusion, indecisiveness, decreased libido, diurnal variation, and psychomotor retardation were scored higher by the subjects. The items of suicidal rumination, psychomotor agitation, constipation, irritability, and weight loss were scored lower.

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