• Title/Summary/Keyword: Orthopedics

Search Result 644, Processing Time 0.023 seconds

Epidemiological Evaluation of Laryngeal Cancer Incidence in Kazakhstan for The Years 1999-2009

  • Igissinov, Nurbek;Zatoskikh, Vera;Moore, Malcolm Anthony;Igissinov, Saginbek;Toulebaeyev, Rais;Mustafina, Meruert;Valieva, Saule;Aldiyarova, Gulmira;Bukeyeva, Zhanar;Venglovskiy, Anatoly
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.6
    • /
    • pp.3969-3974
    • /
    • 2013
  • The purpose was to provide a descriptive epidemiological assessment of the incidence of cancer of the larynx in Kazakhstan and spatial evaluation with gender characteristics. Thgis retrospective study covered all new cases of laryngeal cancer in 11 years (1999-2009). The total number was 4,967 cases, 4,535 (91.3%) in males and 432 (8.7%) in women, with a ratio of 10.5:1. The higher incidence in men compared to women was evident in all age groups, the differences being statistically significant (p<0.05). At the same time revealed a unimodal growth with age, peaking at 70 years and older both sexes. In the dynamics, incidence rates of laryngeal cancer demonstrated a tendency to decrease, in women (T=-6.7%) this being more pronounced than in men (T=-3.3%). Levels were determined to produce cartograms of cancer of the larynx for male and female populations, clear geographical variation being evidenced. The data are discussed with reference to possible risk factors.

Anomalous Insertion of Posterior Horn of Medial Meniscus - A Case Report - (내측 반월상 연골 후각의 비정상적 부착 - 1례 보고 -)

  • Min Byoung-Hyun;Ok Soon-Jong
    • Journal of the Korean Arthroscopy Society
    • /
    • v.5 no.1
    • /
    • pp.45-48
    • /
    • 2001
  • The anterior horn of the medial meniscus is attached to the anterior surface of the tibia. The anterior horns of the medial and lateral menisci are connect with the transverse ligament. The posterior horn of the medial meniscus is firmly attached to the posterior aspect of the tibia just anterior to the insertion of the posterior cruciate ligament. The authors incidentally found an anomalous insertion of posterior horn of medial meniscus into the anterior horn area during arthroscopic examination in the symptomatic knee joint, which had been ruptured anterior cruciate ligament, and report with literature review.

  • PDF

Ewing's Sarcoma/PNET of the Talus - Report of a Case - (거골에서 발생한 유윙 육종/원시신경 외배엽종양 - 1예 보고 -)

  • Kim, Sun-Young;Kwon, Hyuck-Po;Roh, Jae-Su;Cho, Hyoun-Oh
    • The Korean Journal of Cytopathology
    • /
    • v.15 no.2
    • /
    • pp.120-125
    • /
    • 2004
  • Ewing's sarcoma (ES)/PNET is common in both axial and appendicular skeletons, but is extremely rare in the talus. Here, we report a case of ES/PNET of the left talus in a 29-year-old male patient diagnosed by fine needle aspiration cytology, and review the literature on similar cases. The cytological smears were composed of individually dispersed small round cells and occasional clusters of loosely cohesive cells. The tumor cells were fragile, frequently exhibiting naked nuclei. Two distinct types of cells were observed. The light (chief) cells displayed round or slightly oval nuclei with frequent indentations, generally inconspicuous nucleoli, and a thin rim of cytoplasm, which sometimes harbored small vacuoles. The dark cells were smaller, displaying scanty cytoplasm with dense hyperchromatic nuclei, intermixed with chief cells, and often manifesting as small molded groups. However, no significant nuclear pleomorphisms or mitoses were noted. Tumor cells in the ceil block revealed positive cytoplasmic glycogen, as determined by a PAS stain with diastase control, and also exhibited positive immunoreactivity for CD99.

Gemcitabine in Treating Patients with Refractory or Relapsed Multiple Myeloma

  • Zheng, Hua;Yang, Fan
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.21
    • /
    • pp.9291-9293
    • /
    • 2014
  • Background: Patients with refractory or relapsed multiple myeloma are considered to have a very poor prognosis, and new regimens are needed to improve the outcome. Gemcitabine, a nucleoside antimetabolite, is an analog of deoxycytidine which mainly inhibits DNA synthesis through interfering with DNA chain elongation and depleting deoxynucleotide stores, resulting in gemcitabine-induced cell death. Here we performed a systemic analysis to evaluate gemcitabine based chemotherapy as salvage treatment for patients with refractory and relapsed multiple myeloma. Methods: Clinical studies evaluating the impact of gemcitabine based regimens on response and safety for patients with refractory and relapsed multiple myeloma were identified by using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: In gemcitabine based regimens, 3 clinical studies which including 57 patients with refractory and relapsed multiple myeloma were considered eligible for inclusion. Systemic analysis suggested that, in all patients, pooled RR was 15.7% (9/57) in gemcitabine based regimens. Major adverse effects were hematologic toxicity, including grade 3 or 4 anemia, leucopenia and thrombocytopenia i. No treatment related death occurred with gemcitabine based treatment. Conclusion: This systemic analysis suggests that gemcitabine based regimens are associated with mild activity with good tolerability in treating patients with refractory or relapsed multiple myeloma.

Physical Therapy and Rehabilitation of Complex Regional Pain Syndrome in Shoulder Prosthesis

  • Celik, Derya;Demirhan, Mehmet
    • The Korean Journal of Pain
    • /
    • v.23 no.4
    • /
    • pp.258-261
    • /
    • 2010
  • We report a 66-year-old woman with complex regional pain syndrome (CRPS) 1 treated with combined medical and active physical therapy. She was diagnosed with CRPS 1 following partial shoulder prosthesis due to proximal humerus fracture. Despite continuous medication and physical therapy, there was no improvement in her pain and functional outcome. Her overall pain was decreased by stellate ganglion block 3 times in two weeks conducted during the second month of the follow-up period. Following the ganglion blockades, pain and the other symptoms were decreased intermittently but range of motion (ROM) and functional status were not satisfied as much as expected. After the third month of follow-up, her passive and active ROM of the shoulder joint was increased after application of manipulation under general anesthesia. In conclusion, because CRPS 1 remains one of the most difficult pain syndromes, early diagnosis and treatment are important to have adequate functional results from physical therapy. Manipulation under general anesthesia may be an additional effective treatment tool to obtain functional improvement in some patients diagnosed with CRPS 1.