• 대한한방내과학회지
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• 제41권6호
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• pp.933-946
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• 2020

Objective: The aim of this study was to provide a systematic review of the Korean literature on the influence of herbal medicine on liver function. Additionally, we tried to estimate the change in the data on liver function tests (LFTs) and the incidence of liver injury (LI) after taking herbal medicine. Methods: Systematic literature searches were performed on 6 major Korean databases (Research Information Sharing Service (RISS), Korea Institute of Science and Technology information (KISTI), National Assembly Electronic Library, Korean Medical database (KMBASE), Korean Traditional Portal, and Dongui University Electronic Library) from January 2010 to June 2020. No restrictions were placed on the types of publications, which included grey literature. Results: The data indicate that herbal medicine might be a minor cause of LI in Korea. However the results are not supported strongly enough to verify the safety issues because of the limitations of the original studies. Conclusions: Additional well-planned studies are still needed that can overcome the heterogeneity and the considerable methodological flaws in the analyzed studies.

• 대한한의학회지
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• 제32권5호
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• pp.12-24
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• 2011

Objectives: This study analyzed literature published in Korea using Tae-eumin prescriptions and herbs for obesity for future research. Methods: We conducted a computerized search at journal web sites and manual searches. A total of 25 sites were included. Obesity, obese, over weight, herb, herbal, taeum, taeyuem, and taeeum were selected keywords and they were combined properly. Results:A total of 28 studies were analyzed. The percentage of clinical and case report studies was 35.7% and experimental studies 64.3%. The most frequently used prescription was Taeeumjowui-tang (太陰調胃湯) and herbs were Raphani semen(蘿葍子) and Platycodon grandiflorum(桔梗). Weight (kg), body mass index (BMI) and side effects and symptoms were used as indices in clinical and case report studies. Weight, weight gain percentage and blood serum lipid profiles were frequently used as indices in experimental studies. Conclusion: Further well-designed randomized controlled studies and clinical reports of side effects and symptoms are needed for development of obesity studies for Tae-eumin prescriptions.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2014년도 춘계 종합학술대회 논문집
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• pp.309-310
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• 2014

• 고려인삼연구와산업
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• 제5권1호
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• pp.3-6
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• 2011

• 한방비만학회지
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• 제6권2호
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• pp.51-58
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• 2006

Objectives : Obesity causes serious medical complications and impairs quality of life in older persons. We review the literature on the clinical issues related to obesity in elderly and suggest appropriate weight-management guidelines for obese older patients. Methods : PubMed Database and RISS were searched for articles relating to obesity in the elderly. We classified articles according to clinical characteristics, assessments, medical complications, and therapy. Results and Conclusions : The current data show that obesity in elderly is associated with increased mortality, metabolic abnormalities, arthritis, pulmonary abnormalities, urinary incontinence, cancer, and impaired quality of life. Therefore, clinical studies are needed to demonstrate the effectiveness andsafety of weight-loss treatments in obese elderly.

• 대한한의학회지
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• 제44권2호
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• pp.70-105
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• 2023

This study was conducted to examine the current status of traditional korean medicine studies on gastroesophageal reflux disease in Korea, identify deficiencies, and suggest the direction of future medicine research methods to lay the foundation for traditional korean medicine treatment. All domestic papers on the korean traditional treatment of gastroesophageal reflux disease were selected among the literature published until August 2022 in six domestic databases. A total of 52 selected research data were classified into experimental research papers, clinical research papers, and review papers. In experimental papers, to evaluate the effectiveness of treatment, improvement of esophageal mucosal lesions, anti-inflammatory mechanisms, antioxidant mechanisms, esophageal mucosal protection mechanisms, gastric peristalsis control, and gastric acid secretion inhibition mechanisms were used as evaluation measures. In the clinical research paper, the basis for diagnosis of cases was clinical symptoms through medical history listening and diagnosis through visits to hospitals in the past. The average treatment period was 40.7 days, and the duration of treatment was not significantly affected by the duration of the disease. The most widely used Korean medicine treatment intervention was herbal medicine. There were 3 literature review studies, 3 systematic literature review and meta-analysis studies, 1 comparative review study for clinical trial guideline development, all using Chinese papers. This study included all domestic papers on gastroesophageal reflux disease to identify the research trend of the Korean oriental medicine community, and based on this, it is meaningful to confirm areas that need to be supplemented in future research plans.

• 동의신경정신과학회지
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• 제22권3호
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• pp.1-11
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• 2011

Objectives : As the number of patient with dementia increases, interest in mild cognitive impairment (MCI), which is a pre-dementia stage, has been expanding. In this study, we investigated the effects from selected clinical research articles to evaluate the effectiveness of non-pharmacological interventions. Methods : We searched MCI related articles on MEDLINE and the Web of Science using keywords related to MCI. We selected 26 articles, and 13 evaluated efficiency using the Jadad score. Results : Physical exercise and cognitive remediation techniques were effective for improving MCI. Transcutaneous electrical nerve stimulation, taichi, and music belonged to "perhaps" effectiveness group. Many of the 13 articles that evaluated MCI using the Jadad score evaluated them as "good" or "poor", and only three articles evaluated MCI as "excellent". Conclusions : The present evidence suggests that cognitive remediation techniques to improve memory and physical exercise were effective for people with MCI. However, further studies are needed to identify the physical exercise effects.

• Journal of Acupuncture Research
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• 제28권1호
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• pp.109-115
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• 2011

Objectives : This review is to summarize and assess the effects of acupuncture on parasympathetic nervous system(PNS). Methods and Materials : We searched two electronic databases (CNKI, PubMed) for the articles published until Oct. 2010. The randomized clinical trials (RCTs) and uncontrolled clinical trials (UCTs) were considered to be reviewed. We selected four RCTs, seven UCTs and one article which conducted both RCT and UCT, and reviewed them. The quality of RCTs was also assessed with Cochrane criteria. Results : There were four RCTs which reported acupuncture enhanced PNS, and one RCT reported acupuncture reduced PNS. Four UCTs reported acupuncture enhanced PNS, three UCTs reported acupuncture reduced PNS and one UCT reported there was no remarkable change of PNS after acupuncture. Conclusions : Although the majority of reviewed articles showed acupuncture enhance PNS, it is hard to conclude clearly how acupuncture affects PNS due to insufficient quality of trials. Therefore, more trials with strict condition need to be conducted to obviously identify the effects of acupuncture on PNS.

• Journal of Acupuncture Research
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• 제30권5호
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• pp.139-153
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• 2013

Background or Objectives : The purpose of this study is to review oriental medicine journal clinical study in human that have been utilize Electroacupuncture in Korea. Methods : We investigated clinical studies in relation to electroacupuncture through 70 articles from OASIS excluded studies used rats and reviews. Results : Of 162 articles, totally 70 articles selected. There was differences ways of stimulation. In 70 articles, 19 type of instrument is used. About Stimulation time, 15 minutes form 40 percent, 20 minute form 37.1 percent, 30 minute form 11.4 percent. About stimulation intensity, there was 20 articles is unknown intensity. Only 21 articles present intensity by value. In frequency, 2 Hz frequency is used the most, 21 articles. Below 10 Hz frequency is used 54.2 % in 70 articles. There was 7 articles is unknown frequency. Conclusions : The result of this study could provide useful information of field of electroacupuncture is used in oriental medicine. Studies of electroacupuncture should be carried out in many different ways.

• 혜화의학회지
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• 제13권1호
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• pp.331-343
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• 2004

This thesis is a literature study about oriental medicine on insomnia. Insomnia is defined as deficiency of sleeping caused by disability of the period of sleeping and lack of recovery of original vital energy. The main causes of insomnia are the dysfunction of the stomach, the wet phlegm, the deficiency of vigor, Qi of the heart, the lack of Yin, the defect of gall bladder or the excessive anxiety and so on, in the oriental medicine. Insomnia patients, in the oriental medicine, is treated by both removing food stagnancy and regulating the vital function of stomach, controlling the wet phlegm, both nourishing the heart and reinforcing the vital energy, providing vital essence to subdue the fire, tonifing both the heart and spleen or warming the gall bladder, etc. The number of insomnia patients shows a tendency to increase by the stresses of modern society and stimulus caused form the unbalance of Yin and Yang. Medical treatments for insomnia are studied, also, in diverse fields according to the increasing in number of insomnia patients. The literature study about the causes and medical treatments of insomnia is useful for the access to effective oriental medical treatments for insomnia.