• 한국콘텐츠학회논문지
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• 제16권11호
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• pp.767-775
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• 2016

볼거리(mumps)는 타액선을 비롯한 전신에 침범하는 급성 바이러스성 염증 질환으로 일측성 또는 양측성 이하선의 종창과 통증을 동반한다. 볼거리 바이러스는 공기, 타액, 소변으로 다른 사람들에게 전파 되고, 학교, 군대 등 인구밀도가 높은 집단에서 발생하며 양측 고환에 침범하는 경우는 10-60% 정도이다. 사춘기 이후에 남성 볼거리 고환염(mumps orchitis)에 이완되는 경우 1-2개월 후에 감염자의 50%에서 심한 고환 위축과 같은 합병증이 발생한다. 볼거리 고환염은 정자 수, 형태, 운동성 등에 영향을 미치고 정자감소증과 드물게 무정자증으로 인한 불임이 발생한다. 볼거리 고환염이 의심되는 경우 초기 대증적 치료를 적극적으로 함으로써 장차 성인이 되었을 때 무정자증으로 인한 불임을 예방할 수 있을 것으로 생각된다. 본 증례에서는 볼거리 고환염을 앓은 후 무정자증을 보인 2례를 경험하였기에 초음파검사와 정액검사에 대해 참고문헌과 함께 보고하고자 한다.

• Investigative Magnetic Resonance Imaging
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• 제26권1호
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• pp.71-75
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• 2022

Tuberculous epididymo-orchitis, a rare form of extrapulmonary tuberculosis, results from hematogenous dissemination or retrograde extension from the lower urinary tract. Herein, we studied the case of a 22-year-old male patient who presented with refractory left scrotal pain and inflammation. The patient also complained of multifocal pain involving the right buttock, posterior thigh, and right wrist, without trauma history. The patient was diagnosed with multifocal tuberculosis by sputum AFB study and right sacroiliac joint biopsy.

• Clinical and Experimental Reproductive Medicine
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• 제26권1호
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• pp.111-116
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• 1999

Postpubertal mumps may result in ochitis and permanent testicular atrophy may develop following infection. This present study was initiated to evaluate the preventive effect of interferon-${\alpha}2B$ on infertilty after mumps orchitis. There were 21 patients with mumps orchitis between May 1990 and June 1997. Patients were randomly distributed into 2 groups: group 1 patients (n=13) maintained therapy with interferon-${\alpha}2B$ ($3{\times}10^6$ IU per day) and group 2 were managed by conservatively. All of the patients were evaluated with testis size measurement, mumps virus titer, hormone level, and if possible semen analysis. For group 1 patients symptoms disappeared within 2 to 3 days and the volume of testis returned to normal within 11 days and testis atrophy was not observed in all patients in follow up. But asthenospermia was continued in 4 patients (unilateral 2, bilateral 2). For group 2 patients symptoms disappeared within 5 to 6 days and the volume of testis returned to normal within 10 days and testis atrophy was observed in 3 patients (unilateral 2, bilateral 1) in floow up. Asthenospermia was continued in 4 patients (unilateral 2, bilateral 2). Sperm count and morphology were recovered all the recover in group 1, 4 patients had persistent reduced sperm count and morphology in group 2, respectively. These observations suggest that systemic interferon-${\alpha}2B$ treatment is highly effective in preventing infertilty as well as testicular atrophy after mumps orchitis.

• Korean Journal of Radiology
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• 제2권2호
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• pp.117-120
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• 2001

We report a case of adult granulosa cell tumor arising in the scrotal tunics. The patient was a 34-year-old man who presented with right scrotal swelling, first noticed four months previously. Under the initial clinical impression of epididymo-orchitis, antibiotic treatment was instituted but there was no response. The paratesticular nodules revealed by ultrasound and magnetic resonance imaging mimicked intratesticular lesion, and radical orchiectomy was performed. Although several cases of adult testicular granulosa cell tumor, have been reported, the occurrence of this entity in the paratesticular area has not, as far as we are aware, been previously described.

• Clinical and Experimental Pediatrics
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• 제53권5호
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• pp.623-628
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• 2010

The mumps virus is a single-stranded, non-segmented, negative-sense RNA virus belonging to the $Paramyxoviridae$ family. Mumps is characterized by bilateral or unilateral swelling of the parotid gland. Aseptic meningitis is a common complication, and orchitis is also common in adolescents and adult men. Diagnosis is based on clinical findings, but because of high vaccination coverage, clinical findings alone are not sufficient for diagnosis, and laboratory confirmation is needed. Mumps is preventable by vaccination, but despite high vaccination coverage, epidemics occur in several countries, including Korea. Many hypotheses are suggested for these phenomena. In this review, we investigate the reason for the epidemics, optimal methods of diagnosis, and surveillance of immunization status for the prevention of future epidemics.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2000년도 추계학술대회 및 정기총회
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• pp.12-16
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• 2000

In domestic rabbits, pasteurellosis is a primary respiratory disease entity caused by Pasteurella multocida. Respiratory pasteurellsos in rabbits is highly contagious due to dissemination of the organism in the nasal discharge (Benirschke, et al., 1978). The disease reflects a varied and complex host-parasite relationship. Acute infection with high mortality occurs sporadically especially in stressed rabbits less than 10 weeks old, in the form either an enzootic pneumonia, infection of the upper respiratory tract or septicemia. In addition to respiratory form, infection with P. multocida results in a variety of disease processes in rabbits including rhinitis, otitis media, otitis interna, abscesses, metritis, orchitis and meningoencephalaitis (Manning et al., 1989). The deleterious effects of pasteurellosis are common and pose serious problems for rabbit breeders and researchers (Flatt, 1974). (omitted)

• Pediatric Infection and Vaccine
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• 제13권2호
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• pp.191-195
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• 2006

저자들은 임상적 소견과 검사실 소견에서 전염성 단핵구증으로 확진한 환아에게서 폐렴과 흉막 삼출액이 동반된 드문 1례를 경험하였다. 이에 문헌고찰과 함께 보고하는 바이다.

• 셀메드
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• 제9권3호
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• pp.2.1-2.7
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• 2019

Sesame (Sesamum indicum L.) is a rich source of edible oil most commonly it is used as a food product mainly in bakeries and also use as a common source of oil in daily kitchen needs. Due to the presence of some special phytochemicals like proteins, fibers, oil, minerals and antioxidants it is highly used for medicinal and therapeutic purposes. It is a good source of energy and act as an antiaging agent. Its seeds are used as Anti-helmintic, antihypertensive, antimicrobial, cytotoxic and Hepatoprotective but its seed coat which is a byproduct of sesame and a cherished source of fibers is normally use for animal feedstuff. In Unani system of medicine it is used both as drug & diet (dawa wa ghida). In classical Unani literature it is indicated in various disorders like Asthma, Dry Cough, Gastritis (due to any drug, excessive use of alcohol), Dryness of Intestine, Dryness in throat, Renal Stone, Bleeding Piles, Amenorrhea, Retention of urine, Dysuria, Orchitis, Sexual Debility, Anorexia. The present review article, an attempt have been made to compile all the pharmacological and Pharmacognostical characters of Sesamum indicum with special reference to Unani literature.

• 한국산학기술학회논문지
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• 제18권9호
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• pp.123-126
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• 2017

볼거리(mumps)는 유행선 이하선염(epidemic parotitis)으로 불리며, 볼거리 바이러스에 의해 유발되는 바이러스성 감염질환이다. 볼거리는 췌장염, 고환염, 청력장애, 난소염, 이하선염 및 뇌수막염과 같은 합병증을 일으킬 수 있다. 볼거리로 인한 중추신경계의 침범은 볼거리로 진단된 환자의 65%에 달한다는 보고가 있으며, 그 중 대부분은 볼거리 뇌막염(mumps meningitis)이다. 이에 반해 볼거리 뇌염(mumps meningoencephalitis)은 볼거리 환자 6000명당 1명의 경우로 매우 드물다고 알려져 있다. 뇌염은 볼거리바이러스의 흔하지 않은 중추신경계의 합병증으로 홍역-볼거리-풍진 예방접종은 볼거리바이러스로 인한 치명적인 합병증을 예방해주고 경과를 가볍게 해준다고 알려져 있다. 저자들은 24세의 젊은 여자가 이하선염을 동반하지 않은 볼거리 바이러스로 인한 급성 뇌염을 경험하여 이에 대한 사례 연구를 하였다. 환자는 예방접종 시기에 맞춰 볼거리 예방접종을 받았다. 본 병원을 내원 시 환자는 인지능력의 저하를 보였으며 치료 후 빠른 회복을 보였고 합병증은 보이지 않았다. 이 연구는 볼거리 바이러스에 대한 2차 접종을 시기에 맞춰 받은 환자에서 이하선염의 동반 없이 뇌염증상이 발생한 환자에 대한 사례 연구이다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1997년도 춘계학술대회
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• pp.69-69
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• 1997

In the screening of tropical medicinal plants using PAE receptor binding assay, the ether extract of Ardisia crispa showed the potent antagonistic activity. Ardisia crispa have been used to heal the scurf, earache, orchitis, fever and diarrhoea, cough and given to the mother after childbirth to ‘wash out dirty blood’ in Malaysia. By means of activity guided isolation, compound AC7-1 was isolated as the potent PAF antagonist. In this study, antiplatelet effects of compound AC7-1 were examined in vitro platelet aggregation assay using the chronolog aggregometer. Compound AC7-1 inhibited PAF-, collagen-, ADP-, thrombin-induced platelet aggregation in human, rabbit and rat platelet rich plasma. In vitro rabbit platelet aggregation, the IC$\_$50/ value of compound AC7-1 was 5 ${\times}$ 10$\^$-6/ M against PAF(5 ${\times}$ 10$\^$-7/M)-induced aggregation. The IC$\_$50/ values of AC7-1 on PAF-induced platelet aggregation increased with increase of the concentration of PAF used. This result suggested the competitive nature of the AC7-1 antagonism. In vitro rat platelet aggregation, the IC$\_$50/ values of AC7-1 on collagen-, ADP-induced platelet aggregation were 4 ${\times}$ 10$\^$-6/ M, 2 ${\times}$ 10$\^$-5/ M, respectively. Also in vitro human platelet aggregation, AC7-1 potently inhibited both the primary phase and secondary phase of thrombin-induced aggregation.