• 치위생과학회지
• /
• 제8권3호
• /
• pp.169-173
• /
• 2008

본 연구는 2007년 3월10일부터 2007년 6월3일까지 충남 당진에 위치한 S대학 치위생과 3학년들의 치면세마 실습환자 248명을 대상으로 치간칫솔 사용에 따른 치면세균막 제거효과를 비례오즈모형(proportional odds models)을 사용하여 분석한 결과 다음과 같은 결론을 얻었다. 1. 비례오즈모형의 적합도는 자유도가 3인 1.2552이고 p값이 .7398로 비례오즈모형이 적절함을 의미하고 치면세균막 제거효과와 치간칫솔 사용의 독립성문제는 $H_0:{\beta}=0$에 대한 검정으로 검정통계량은 자유도가 1인 15.5496이고 p 값은 <.0001 이다. 이는 치면세균막 제거 효과와 치간칫솔의 사용은 매우 연관성이 높음을 의미한다. 2. 모형의$\beta$에 대한 ML추정치는 $\hat{\beta}=1.2493$(ASE = 0.3207)임을 알 수 있고 반응이 매우 불량이다 보다는 매우 양호하다 에 속할(이를 라 표현할 수 있다) 경향은 치간칫솔을 사용하지 않는다. 라는 반응에 비해 치간칫솔을 사 용한다. 라는 경향이 추정오즈비 exp(1.2493) = 3.49배 높다. 3. 비례오즈모형의 추정반응은 치간칫솔을 사용한다. 라는 반응이 매우양호와 양호한 치면세균막 제거효과에 속할 추정(누적)확률은 0.38(0.50)이다.

• 한국임상수의학회지
• /
• 제22권1호
• /
• pp.31-35
• /
• 2005

This study was performed to investigate of dental plaque, calculus and gingival inflammation in Beagle dogs. Forty adults Beagle dogs (28 male and 12 female) were used in this study. The dogs weighed 9.5 kg and were in good oral and systemic health as determined by physical examination, and all dogs had full and normal dentition. The dogs were given a commercial pellet feed during 2 years period. For all examination procedures, the dogs were premedicated with a subcutaneous injection of atropine sulfate (0.04 mg/kg). Anesthesia was induced and maintained by intravenous administration of ketamine (8 mg/kg) and xylazine (2 mg/kg). Dental plaque, calculus and gingival inflammation were assessed by Logan and Boyce clinical plaque index. Calculi covering the maxillary carnassial and first molar teeth were extensive and were accompanied by severe gingival inflammation and pocket formation. Calculi, accompanied by gingival inflammation, were clearly evident on buccal surfaces of other teeth. Calculi didn't showed on the lingual surfaces, but linguogingival inflammation formed in premolar teeth. Although the general pattern was clear, there was considerable variation among dogs in the rate of deposition of calculus and extend of gingival inflammation. This investigation suggest that feeding of the commercial dry food without dental hygiene increase plaque accumulation and may be a contributing factor in calculi formation and periodontal disease.

• 대한소아치과학회지
• /
• 제37권2호
• /
• pp.186-192
• /
• 2010

Streptococcus mutans는 구강 내에 상존하는 치아우식증의 주요 원인균으로서 치면의 피막에 부착 후 glucan을 형성하여 세균의 군락을 이루며, 외부로부터 공급된 자당대사를 통하여 유기산을 생성함으로써 법랑질을 탈회시킨다. 치아우식 활성도의 평가를 위한 단클론항체를 이용한 방법은 진료실에서 빠른 시간 내에 간편하게 타액에 존재하는 Streptococcus mutans의 정량분석이 가능한 방법이다. 이 연구는 3세에서 6세 사이의 어린이 15명을 대상으로 자극성 타액을 채취하여 시판 중인 단클론항체를 이용한 Salivacheck$^{TM}$ Mutans, strip을 이용한 Dentocult$^{(R)}$-SM 그리고 MSB배지 배양법으로서 타액 내 Streptococcus mutans를 측정한 후 그 값을 우식경험치아수와 비교하여 상관관계를 알아보았다. Saliva-check$^{TM}$ Mutans를 이용한 방법은 Dentocult$^{(R)}$-SM과 MSB배지법과 통계학적으로 유의한 상관관계를 보였으나(p<0.05), MSB배지법은 어린이의 우식경험치아수와 통계학적으로 유의한 결과를 나타내지 않았다(p=0.34).

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제47권6호
• /
• pp.445-453
• /
• 2021

Objectives: Periodontitis is the most common chronic disease that causes tooth loss and is related to systemic diseases such as cardiovascular disease and diabetes. An objective indicator of the current activity of periodontitis is necessary. Soluble forms of the receptor for advanced glycation end products (sRAGE) are markers that reflect the status of inflammatory diseases. In this study, the relationship between sRAGE and periodontitis was analyzed to determine whether it can be used to diagnose the current state of periodontitis. Patients and Methods: Eighty-four patients without any systemic diseases were diagnosed with periodontitis using three classifications of periodontitis. Demographics and oral examination data such as plaque index (PI), bleeding on probing (BOP) index, and probing pocket depth (PPD) were analyzed according to each classification. In addition, correlation and partial correlation between sRAGE and the values indicating periodontitis were analyzed. Results: In each classification, the level of sRAGE tended to decrease if periodontitis was present or severe, but this change was not statistically significant. sRAGE and periodontitis-related variables exhibited a weak correlation, among which the BOP index showed a relatively strong negative correlation (ρ=-0.20). Based on this, on analyzing the correlation between the BOP index and sRAGE in the group with more severe periodontitis (PPD≥5 mm group, severe group of AAP/CDC [American Academy of Periodontology/Centers for Disease Control and Prevention], periodontitis group of López), the correlation further increased (ρ=-0.23, -0.40, -0.50). Partial correlation analysis of the sRAGE and BOP index showed a stronger negative correlation (ρ=-0.36, -0.55, -0.45). Conclusion: sRAGE demonstrated a tendency to decrease upon increased severity of periodontitis according to the classifications used. Above all, the correlation with the BOP index, which reflects the current state of periodontitis, was higher in the group with severe periodontitis. This indicates that the current status of periodontitis can be diagnosed through sRAGE.

• 한국콘텐츠학회논문지
• /
• 제10권8호
• /
• pp.240-248
• /
• 2010

본 논문은 SLS의 함유정도를 다르게 한 A(0%), B(1.1%), C(2.2%)의 세가지 실험세치제를 제작하여 구강 내 변화를 50명씩 세 그룹(A, B, C)으로 나누어 실험하였다 본 연구결과 SLS함량에 따른 세치제의 4주간 사용 후 3집단의 치면세균막 검사( PHP )에서 집단간차이가 나타났고 SLS함량이 높을수록 PHP의 지수가 낮아졌다. 또한 간이구강위생지수(OHI-S)에서는 A, B, C 세집단 모두에서 OHI-S 값이 줄었다. 또한 PHP와 OHI-S는 높은 상관성을 보였다. SLS함량에 따른 세치제의 4주간사용 후 3집단의 타액분비량 측정 시 SLS함량이 높아질수록 타액량이 감소하였고, 타액의 점조도 및 pH에는 변화가 없었다. SLS가 구강건조를 유발함을 뒷받침하는 결과로 SLS와 타액의 분비량은 음의 상관관계를 보였다.

• 대한치과교정학회지
• /
• 제53권6호
• /
• pp.374-392
• /
• 2023

Objective: Assess and evaluate the different indicators of oral health-related quality of life (OHRQoL) among patients treated with clear aligners (CAs) versus those treated with conventional fixed orthodontics (FAs). Methods: An electronic search was performed on the database is Web of Science, Scopus, and Embase databases. Randomized and non-randomized control trials, cross-sectional, prospective cohort and retrospective trials were included. Quality was assessed with risk of bias tool and risk of bias in non-randomised studies. Meta-analyses were performed with random effects models, estimating the standardized and non-standardized mean differences, odds ratio and risk ratio as the measure of effect. The effect on time was determined using a meta-regression model. Results: Thirty one articles were included in the qualitative synthesis and 17 in the meta-analysis. CAs had a significantly lower negative impact on QoL, with an "important" effect size, while the influence of time was not significant. Periodontal indicators plaque index (PI), gingival index (GI), probing depth (PD), and bleeding on probing show significantly better values in patients treated with CAs, with moderate to large effect sizes. PI and GI have a significant tendency to improve over time. In microbiological indicators, CAs present a lower biofilm mass without differences in the percentage of patients with high counts of Streptococcus mutans and Lactobacilli bacteria. The risk of white spot lesion onset is ten times lower in carriers of CAs. Conclusions: Patients wearing CAs show better periodontal indicators, less risk of white spot development, less biofilm mass and a better QoL than patients with FAs.

• Journal of Periodontal and Implant Science
• /
• 제32권1호
• /
• pp.41-49
• /
• 2002

The aim of this study was to compare periodontal conditions around mesially tipped molars by a tipping degree. Patients who had been consecutively treated at the Department of Periodontology, Chonbuk National University Hospital from October 1999 to August 2001 were assessed with radiographs taken at their molar regions. Of all molars investigated, 142 molars of 116 patients tipped mesially more than 10 degrees to the line perpendicular to an occlusal plane were selected for the study. The tipped molars were divided into 2 groups with a reference to a tipping degree, i.e., 66 slightly tipped(group 1 : <$30^{\circ}$) and 76 severely tipped molars (group 2 : ${\geq}30^{\circ}$). Probing depth(PD), plaque retention index(PRI) at mesial surfaces of tipped molars and tooth mobility(TM) were recorded at the clinical examination. Tipping degree(TD) and alveolar bony defect(ABD) at the mesial surface of the molars were measured in a radiograph. The results showed that no statistical differences were found between groups in all measured variables. In Pearson correlation analysis performed in the same group, a positive relationship was shown between PRI and PD in the group 1 and, in the group 2, between PRI and PD as well as PRI and ABD(p < 0.01). However, no statistically significant relationship was found between TD and all other variables in both groups. Within limitations of this study, it may be concluded that tipping degree did not seem to influence periodontal conditions, i.e., PD, ABD and TM of mesially tipped molars per se, but plaque presence/absence seemed to mainly affect the periodontal conditions of the tipped molars.

• 대한소아치과학회지
• /
• 제33권3호
• /
• pp.411-421
• /
• 2006

치열이 발육 중에 있는 소아는 치은 및 치주 질환에 매우 흔하게 이환된다. 이 시기의 치은염은 대개 경미하며 가역적인 경우가 많으나, 만성적으로 진행하여 성인기의 치주질환으로 이행되는 경우도 발생한다. 소아의 치은 평가를 위한 방법으로 흔히 임상적인 치은염 평가 지수나 구강 위생 지수를 측정하게 된다. 치은염 측정 지수의 하나로써 치은 열구액은 치주조직과 치은 열구로부터 유래되는 염증성 삼출물로, 세균성 치태의 점진적인 축적에 대한 반응으로 증가한다고 알려져 있다. 본 연구에서는 소아의 치은 상태 평가를 위해 전북대학교 병원 소아치과에 내원한 3-14세(평균 $8.5{\pm}3.1$세)의 어린이 50명과 23-33세 (평균 $26.1{\pm}3.3$세)의 성인 20명을 대상으로 육안적 지수인 치은지수와 치태지수를 조사하였다. 또한 이와 함께 치은 열구액을 채취하여 그 부피를 Periotron 8000(Oraflow Inc., USA)을 이용하여 측정하였고, 소아와 성인의 수치를 비교 분석한 결과 다음의 결론을 얻게 되었다. 1. 어린이에서 유치열기와 영구치 맹출기, 맹출 완료기의 각 군 간에 치은 열구액 부피를 비교했을 때, 평균치는 영구치 맹출기에서 가장 높게 나타났으나 통계적으로 유의한 차이를 보이지 않았다(p>0.1). 2. 어린이와 성인을 비교하였을 때 치은 열구액 부피는 어린이에서 유의성 있게 크게 나타났다(p<0.001). 3. 어린이와 성인 모두 임상적인 치은지수(GI)와 치태지수(PLI)는 치은 열구액의 부피와 유의성 있는 상관관계를 보였다(GI; r=0.394, p<0.001 PLI; r=0.642, p<0.001). 4. 치은 열구액을 채취한 치아의 교정 치료 유무는 치은 열구액의 부피와 유의성 있는 양의 상관관계를 보였다(p<0.001). 그러나 레진 치료 유무나 치아 우식의 유무는 관계가 없었다(p>0.05). 5. DMFT치는 유치열기에서 영구치열기보다 높게 나타났다(p<0.001). 또한 DMFT치와 치은 열구액 부피는 유의성 있는 상관관계를 보이지 않았다(p>0.1).

• Journal of Periodontal and Implant Science
• /
• 제44권6호
• /
• pp.280-287
• /
• 2014

Purpose: The purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling and root planing (SRP) in patients with chronic periodontitis. Methods: The study was conducted from December 2013 to May 2014 at Ewha Womans University Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderate chronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio: SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performed thrice a day for a month by using electric toothbrushes with embedded light-emitting diodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing were assessed before (baseline) and four weeks after (follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacterium nucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcus mutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chain reaction at the same points in time. Results: The clinical parameters improved in both the groups. At the follow-up assessment, PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CAL showed significantly greater changes in the SRP+PT group than in the SRP group (PPD, P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but no significant intergroup differences were noted. Conclusions: Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobial effects is not sufficient. Long-term studies are necessary to develop the most effective PT protocol and compare the effectiveness of PT with and without exogenous photosensitizers.

• 한국치위생학회지
• /
• 제7권1호
• /
• pp.61-72
• /
• 2007

The purposes of this study were to investigate the oral health status of the disabled children attending special schools in Seoul and Gyeonggi area, which were to collect baseline data for set up a oral health center in special schools. The study group comprised 915 disabled children aged 12~15 year. They were examined clinically and surveyed on 4 oral health related characteristics according to the type and level of disabilities The results may be summarized as follows: 1. DMFT index was the highest in children with crippled disorder. The plaque control was more required to the children with mental retardation or developmental disorder other than another types of disabilities. 2. About one third of the children with mental retardation or developmental disorder had their teeth brushed at least 3 times daily without any help. Over the half of the children with crippled disorder had their teeth brushed 2 times daily, 33.3% were independent and 38.9% totally dependent on help from others. 3. The more level of disabilities was higher, the more frequency of tooth brushing was lower and degree of dependance of the tooth brushing was higher. 4. There was tendency to visit to dental office more frequently for relief of dental symptoms in children with crippled disorder 5. The inability to call for help from others was the major barrier to dental care for the disabled.