• 한국콘텐츠학회논문지
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• 제16권5호
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• pp.601-611
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• 2016

구술심리주의의 확산, 국민참여재판의 도입 등 빠른 변화의 흐름 가운데 놓여있는 한국의 법정 환경은 구술주의의 단점을 효과적으로 보완할 수 있는 법정 프레젠테이션의 체계적인 도입을 필요로 하고 있다. 이에 본 연구에서는 한국의 법정 환경을 토대로 법정 프레젠테이션의 개념과 유형, 그리고 효용성을 정리 및 분석하였다. 또한 법정 프레젠테이션의 특수성을 고려하여 미국과 한국에서 가장 범용으로 사용되는 법정 프레젠테이션 도구들을 비교 분석하였다. 이러한 분석을 토대로, 한국의 법정 환경에 최적화된 프레젠테이션 도구가 갖춰야할 요소로서 1. 다양한 형태 매체의 삽입 용이성, 2. 그래픽 스타일 스펙트럼의 적절한 제한, 3. 그래픽 도구의 사용 편의성, 4. 시스템적 기능성 등의 요소를 제안하였다. 이와 같은 제안은 주장 전개와 내용 전달에 있어서 명료성, 정확성, 효율성 등을 강화할 뿐만 아니라 프레젠테이션 비주얼커뮤니케이션 측면의 심미성과 통일성을 증진하기 위한 것이다.

• The Journal of Advanced Prosthodontics
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• 제11권2호
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• pp.75-80
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• 2019

PURPOSE. The purpose of this study is to investigate the effects of aging and various risk factors on the oral environment and to analyze them in 3-dimensions. MATERIALS AND METHODS. A total of 800 patients were enrolled in this study, and subjects were divided into 4 groups by age-under 55, 56 - 65, 66 - 75, and over 76. Based on their most recent visit, the number of crowns, bridges, implants, and the remaining natural teeth were recorded. Smoking habits, along with presence of diabetes and hypertension, were surveyed, as risk factors were also set as a variable. Comparisons among the groups or within the groups were performed by independent t-test, and one-way and two-way ANOVA. Kruskal-Wallis test and Mann-Whitney U test were used for analysis. It was assumed to be statistically significant when P value is below .05. RESULTS. Changes in the number of crowns, bridges, implants, and the remaining natural teeth by age were statistically significant. When we examined the effect of risk factors on the change of variables with age, hypertension was found to affect the number of bridges. Diabetes and smoking were found to affect the number of the remaining natural teeth. The other variables were not statistically significant. CONCLUSION. Aging is considered to be an important variable affecting the change of oral environment. Among the risk factors, the presence of smoking habit and diabetes is thought to have a great influence on the change of the number of the remaining natural teeth.

• 융합정보논문지
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• 제7권6호
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• pp.9-17
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• 2017

본 연구는 소방공무원의 구강건강관리 행동에 대한 실태를 파악하고자 대전광역시의 일부 소방서에 근무하는 241명의 소방공무원을 대상으로 실시하여 다음과 같은 결과를 얻었다. 첫째, 1일 칫솔질 횟수는 남성은 3회, 여성은 4회라는 응답이 많았고, 칫솔질 시간은 20대 연령과 근무경력이 5년 이하인 근무자들이 3분 이상 닦는 것으로 나타났다. 둘째, 구강보조용품 사용은 20, 30대 연령과 근무경력이 10년 미만인 근무자들이 많이 사용하고 있었으며, 소방장 이하의 계급에서 구강보건교육 경험이 많았다. 셋째, 구강보건교육을 받은 경우 구강보조용품을 더 많이 사용하고 있었고, 1년 내 치석제거도 더 많이 시행한 것으로 나타났다. 연구결과 열악한 근무환경에 비해 소방공무원의 구강건강관리상태는 다행히 양호한 수준 이였으나, 향후 구강건강향상을 위한 IT와 로봇기술이 융합된 직무 맞춤형 구강건강 프로그램 개발과 홍보대책 방안을 마련하고 소방공무원의 처우를 개선한다면 소방공무원들의 구강건강관리 수준은 더 향상될 수 있을 것이라 사료되었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권5호
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• pp.267-275
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• 2019

Objectives: Metastasis in oral squamous cell carcinoma (OSCC) can occur in a variety of ways, and draining lymphatics and lymph nodes serve as a common route. Prior to metastasis, lymph nodes elicit an immune response to either wall off or create a favorable environment for homing of tumor cells. This immune response to tumor stimuli is visualized by recognizing various immunoreactive patterns exhibited by the lymph node. The present study aims to evaluate the role of immuno-morphologic patterns of the lymph node in neck dissection for cases of OSCC. Materials and Methods: Our retrospective study included 50 neck dissection cases of OSCC and a total of 1,078 lymph nodes. The grades of primary tumors with eight different immunoreactive patterns were compared. Vascularity and metastasis in lymph nodes were also evaluated. Results: The lymphocyte predominant pattern was the most common immunoreactive pattern found in 396 of 1,078 lymph nodes. Patterns of lymphocyte predominant (P=0.0005), sinus histiocytosis (P=0.0500), paracortical hyperplasia (P=0.0001), cortical hyperplasia (P=0.0001), and increased vascularity (P=0.0190) were significantly associated with tumor grade. Conclusion: The present study adds to the understanding of lymph node immunoreactivity patterns and their correlation with tumor grade. We recommend further study of lymph node patterns for all sentinel lymph node biopsies and routine neck dissections for OSCCs.

• Restorative Dentistry and Endodontics
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• 제25권4호
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• pp.587-598
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• 2000

Urea in the oral cavity is hydrolyzed mainly by bacterial ureases to ammonia, which in turn, raises pH of the oral environment, maintaining oral pH homeostasis, thereby inhibiting dental caries. Streptococcus salivarius has been shown to be a major contribution to oral ureolysis. Synthesis of urease by S. salivarius appears to be constitutive, but can be greatly enhanced in the acidic environment. It has been presumed that ureolytic activity of S. salivarius strains isolated from caries-active site is greater than that of strains from caries-free site. However, no in vivo study has supported the presumption. The present study was performed to observe the ureolytic activity of S. salivarius strains isolated from different environments in the same individual, finding out whether the ureolytic activity is related to dental caries. For the purpose, S. salivarius strains were isolated from caries-active site (>C2), a caries-free site of the tooth, and the dorsum of the tongue of each of 50 patients having decayed teeth. The strains isolated from the patients who harbored S. salivarius in more than two sites were selected and then their ureolytic activities were measured. In order to examine clonal diversity of the strains, their ureC genes were amplified by polymerase chain reaction (PCR) and then restricted with EcoRV, and the protein profiles of the strains were compared by SDS-PAGE. The results were as follows: 1. Of 50 patients, 13 patients harbored S. salivarius in more than two sites; a total of 61 S. salivarius strain were isolated from the patients and selected for the study. 2. Of 17 isolates from the caries-active site of 9 patients harboring S. salivarius in more than two sites including carious lesion, 10 (58.8%) showed a high ureolytic activity (> 200 ${\mu}mol/min/mg$). While, 19 out of 44 isolates (43.2%) from the caries-free site of the teeth and the dorsum of the tongues of 13 patients were the strains with a high ureolytic activity. 3. Of 9 patients harboring S. salivarius in more than two sites including caries-active site. 6 patients were found to have the strains in the caries-active site showing a lower ureolytic activity than the strains in the other sites. 4. Of 34 isolates with ureolytic activity higher than 40 ${\mu}mol/min/mg$, 32 isolates produced 0.54-Kbp PCR products regardless of the sites of bacterial collection. In contrast, of 27 isolates with ureolytic activity lower than 40${\mu}mol/min/mg$, 26 isolates yielded 1.3-Kbp PCR products or none regardless of the sites. 5. Different clonal types of S. salivarius with relatively higher and lower ureolytic activities were found in the same individuals and even in the same sites. 6. None of strains showing different ureolytic activity appeared to be the same clonal type. The overall results suggest that ureolytic activity of the isolates does not appear to be related to differences of the environments but related to their own genetic traits.

• 대한물리의학회지
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• 제3권4호
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• pp.247-254
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• 2008

Purpose : The purpose of this study was to analyze some factors that can cause incidence of the muscle and skeletal system trouble, by which Dental Hygiene Students examine the pain and the inconvenient feeling according to kinds in manual implements and the usability in the level of manipulating and maintaining the manual implement, in the actual training of the intra oral cavity along with mannequin given the scaling practice. Methods : Targeting 18 female juniors for the department of dental hygiene, who had directly practiced oral prophylaxis for 2 years, the questionnaire research was carried out right after the mutual practice in the intra oral cavity along with mannequin. Results : It was indicated that there is no big difficulty both in intra oral cavity and mannequin in terms of manipulating implement with a method of maintaining the rightly hand fixing or of grasping the trans formative pencil and of controlling force given manipulating the implement. How to grasp a trans formative pencil was indicated to be more difficult in the intra-oral manipulation(p<.05). Pain and inconvenient-feeling level, which occur in muscle and skeletal system during practicing the scaling in mannequin, were indicated to be in order of shoulder, wrist, neck, waist, elbow, and headache. Conclusion : There was no big difference in the pain and the inconvenient feeling in muscle and skeletal system according to mannequin and intra-oral environment given manipulating tile manual implement. However, there was difference in manipulating the implement with a method of grasping transformative pencil. The pain and inconvenient feeling in muscle and skeletal system were the highest both in shoulder and wrist.

• Journal of Preventive Medicine and Public Health
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• 제15권1호
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• pp.131-137
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• 1982

For the purpose of the curative effects of oral D-penicillamine in lead poisoning, D-penicillamine was orally administered to 7 lead poisoned workers which were employed in glaze product industry dealing with the lead oxide ($Pb_3O_4$). The doses of D-penicillamine was 1,200mg per day which was administered by oral 7days schedules, taking for 5 days and stopping for the following 2days, repeatedly during 3 months period. (All the poisoned workers started working again in that industry after 1 month treatment, and were treated by oral D-penicillamine for 2 months still being exposed to contaminated environment.) In order to evaluate the curative effects of D-penicillamine, 10gm of whole blood and 24 hours urine were collected every 14 days during the curative period for laboratory analysis(hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, urine coproporphyrin, and urine lead levels) with the observation of the clinical symptoms. The results were as follows; 1. Oral D-penicillamine effected good curative results as that hemoglobin, blood lead, urine $\sigma$-aminolevulinic acid, and urine coproporphyrin levels were decreased below the critical level within 1 month treatment. 2. After re-exposure, oral D-penicillamine effected to some extent as that urine lead level was decreased below the critical level after 3 months treatment with disappearence of the clinical symptoms after 2 months treatment. However, the curative effects of oral D-penicillamine in the lead exposure state is questionable since increasement of blood lead level and remarkable decreasement of urine lead level after 3 months treatment can be observed.

• International Journal of Oral Biology
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• 제45권2호
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• pp.58-63
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• 2020

The salivary glands secrete saliva, which plays a role in the maintenance of a healthy oral environment. Under physiological conditions, saliva secretion within the acinar cells of the gland is regulated by stimulation of specific calcium (Ca²⁺) signaling mechanisms such as increases in the intracellular Ca²⁺ concentration ([Ca²⁺]_i) via storeoperated Ca²⁺ entry, which involves components such as Orai1, transient receptor potential (TRP) canonical 1, stromal interaction molecules, and inositol 1,4,5-triphosphate (IP₃) receptors (IP₃Rs). Homer proteins are scaffold proteins that bind to G protein-coupled receptors, IP₃Rs, ryanodine receptors, and TRP channels. However, their exact role in Ca²⁺ signaling in the salivary glands remains unknown. In the present study, we investigated the role of Homer2 in Ca²⁺ signaling and saliva secretion in parotid gland acinar cells under physiological conditions. Deletion of Homer2 (Homer2^-/-) markedly decreased the amplitude of [Ca²⁺]_i oscillations via the stimulation of carbachol, which is physiologically concentrated in parotid acinar cells, whereas the frequency of [Ca²⁺]_i oscillations showed no difference between wild-type and Homer2^-/- mice. Homer2^-/- mice also showed a significant decrease in amylase release by carbachol in the parotid gland in a dose-dependent manner. These results suggest that Homer2 plays a critical role in maintaining [Ca²⁺]_i concentration and secretion of saliva in mouse parotid gland acinar cells.

• 한국산학기술학회논문지
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• 제18권10호
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• pp.513-523
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• 2017

구강보건 관련 취약계층에 해당하는 거주 장애인의 개인위생과 구강위생 업무수행의 어려움의 정도 및 구강보건 수행환경을 알아보고자, 경기도 장애복지 시설 생활재활교사에게 설문조사를 실시하여 총 111부를 기술통계와 상관분석으로 분석한 결과는 다음과 같다. 첫째, 거주 장애인의 개인위생은 자발적인 칫솔질, 칫솔질 중요도 인식, 자신의 칫솔 찾기와는 정적 상관을 보였다. 둘째 거주 장애인의 구강위생 수행과 관련한 어려움의 정도는 자신의 칫솔 찾기, 치과 의료기관의 구강검사 여부에서 보통이상을 수행할 수 있는 것으로 나타났고, 자발적 수행정도에서는 잇몸 맛사지, 설탕 함유 식품 자제순으로 잘하지 못하는 것으로 나타났다. 셋째, 자발적인 칫솔질을 잘 수행할수록 올바른 칫솔질 방법 등에 대한 교육을 적절하게 받고 있는 것으로 나타났으며, 3분 이상 칫솔질과 회전법 칫솔질을 스스로 잘 수행 할수록 구강관리용품을 적절하게 지원받고 있는 것으로 나타났다. 또한 혀 닦기를 잘 수행할수록 담당 장애인의 수는 적절한 것으로 나타났다. 따라서 거주 장애인이 개인위생을 실천하기 어려운 경우, 구강위생 실천에 도움을 줄 수 있는 생활재활교사 및 장애인에게 지속적인 치위생 중재 프로그램이 필요할 것으로 보인다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제29권6호
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• pp.494-498
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• 2007

Pleiotrophin or osteoblast-specific factor 1(HOSF-1) is a growth-associated protein present in bone matrix. This study was designed to study pleiotrophin expression in osteoblastic cells. Pleiotrophin was expressed by osteoblast-like cell line. Pleiotrophin expression increased following the proliferative phase and was minimal at the terminal phases of the induced differentiation of cultured MC3T3-E1 cells. Pleiotrophin expression represents another autocrine factor that may contribute to the physiologic control of induced bone formation. In this study, induced osteogenesis will be examined in the context of the osteoblast expression of and regulation by PTN. I hypothesized that PDGF-BB stimulation of PTN expression represents an important paracrine signal during the induced osteogenesis associated with periodontal and implant surgeries. The possible mediation by PTN of anabolic effects attributed to PDGF-BB stimulation was examined in cell culture models of osteoblast differentiation. These studies will contribute fundamental insights to osteoblast biology and insights regarding the potential use of factors such as PTN in the clinical environment.