• Imaging Science in Dentistry
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• v.39 no.4
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• pp.185-189
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• 2009

Purpose : The purpose of this study was to investigate how to detect proximal caries using line profile and validate linear measurements of proximal caries lesions by basic digital manipulation of radiographic images. Materials and Methods : The X-ray images of control group (15) and caries teeth (15) from patients were used. For each image, the line profile at the proximal caries-susceptible zone was calculated. To evaluate the contrast as a function of line profile to detect proximal caries, a difference coefficient (D) that indicates the relative difference between caries and sound dentin or intact enamel was measured. Results : Mean values of D were $0.0354{\pm}0.0155$ in non-caries and $0.2632{\pm}0.0982$ in caries (p<0.001). Conclusion : The mean values of caries group were higher than non-caries group and there was correlation between proximal dental caries and D. It is demonstrated that the mean value of D from caries group was higher than that of control group. From the result, values of D possess great potentiality as a new detection parameter for proximal dental caries.

• Journal of Korean society of Dental Hygiene
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• v.19 no.2
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• pp.265-275
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• 2019

Objectives: The aim of this study was to investigate trends of oral health behaviors in Korean adolescents. Methods: From the 2005 to 2017 Korea Youth Risk Behavior web-based Survey (KYRBS) Secondary Data (study to 748,461). Independent variables were the year, gender, grade, and living area. Dependent variables were the rate of tooth-brushing after lunch, scaling, use of sealant, and oral health education within 1 year. Chi-squire tests were used to estimate the rate of oral health behaviors and trends. In addition, multiple logistic regression analysis was used to estimate the association between socio-economic characteristics and oral health behaviors. The analyses were conducted using IBM SPSS statistics 21 (version 21.0, IBM Corporation, New York, NY, USA). Results: The rate of tooth-brushing after lunch and use of sealant have significantly increased every year. Oral health behaviors were significantly associated with socio-economic characteristics. The rate of oral health education was higher among males than females, which was in contrast to other oral health behaviors. The scores for tooth-brushing after lunch, use of sealant, and scaling in females were 2.33 (95% CI; 2.27-2.40), 1.31 (95% CI; 1.29-1.33), and 1.20 (95% CI; 1.18-1.22), which were higher than those in males. The score for use of sealant in the highest household economy group was 1.13 (95% CI; 1.10-1.17), which was higher than the lowest economy group. Conclusions: We found positive trends of oral health behaviors in Korean adolescents.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2807-2811
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• 2015

Scorpion venom peptides recently have attracted attention as alternative chemotherapeutic agents that may overcome the limitations of current drugs, providing specific cytotoxicity for cancer cells with an ability to bypass multidrug-resistance mechanisms, additive effects in combination therapy and safety. In the present study, BmKn-2 scorpion venom peptide and its derivatives were chosen for assessment of anticancer activities. BmKn-2 was identified as the most effective against human oral squamous cells carcinoma cell line (HSC-4) by screening assays with an $IC_{50}$ value of $29{\mu}g/ml$. The BmKn-2 peptide killed HSC-4 cells through induction of apoptosis, as confirmed by phase contrast microscopy and RT-PCR techniques. Typical morphological features of apoptosis including cell shrinkage and rounding characteristics were observed in treated HSC-4 cells. The results were further confirmed by increased expression of pro-apoptotic genes such as caspase-3, -7, and -9 but decrease mRNA level of anti-apoptotic BCL-2 in BmKn-2 treated cells, as determined by RT-PCR assay. In summary, the BmKn-2 scorpion venom peptide demonstrates specific membrane binding, growth inhibition and apoptogenic activity against human oral cancer cells.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.25 no.1
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• pp.99-107
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• 1995

The aim of this study was to evaluate clinician's detectability in the diagnosis of bone loss in the bifurcation of mandibular molars on periapical radiographs and Digital images. Periapical radiographs were obtained of the first molars in 2 dry mandibles after preparation of bony defects corresponding to degree I, degree II and degree III buccal furcation involvements. The radiographs were randomly presented to 39 clinicians(1 oral radiologist, 4 periodontist, 34 general dentists) who were asked to determine the presence or absence of bone loss. Periapical films were digitized with a TV camera. Digital images were assessed by 15 clinicians(1 oral radiologist, 4 periodontist, 10 general dentists). I. the overall diagnostic accuracy of Digital images for detection of bone loss in the bifurcation of mandibular molars was higher than that of the periapical radiographs. 2. the largest increase in diagnostic accuracy was found between lesion grade II and III on both radiographs and Digital images(P<0.05). 3. there was no significant difference between the standard state and the controlled contrast state on Digital images. 4. the overall diagnostic accuracy of I radiologist and 4 periodontists was better than that of the general dentists for detecting bifurcation involvements.

• English Language & Literature Teaching
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• v.12 no.1
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• pp.183-204
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• 2006

This study investigated the effects of rehearsed English drama activities on the learner variables and oral communication achievements of Korean elementary school students. Forty children in the treatment group participated in the drama activities while forty-two children in the contrast group participated in the regular classes. The results of the study are as follows: the treatment group showed significant differences between the pre-tests and the post-tests in language learning strategies, motivation, confidence, perceived competence, willingness to communicate, and listening and speaking achievements; the students in the treatment group progressed in their attitudes toward and participation in the classroom activities. Based on the findings, it is concluded that the rehearsed drama activities positively affect the learner variables and oral communication. The pedagogical implications are discussed in the conclusion.

• Imaging Science in Dentistry
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• v.38 no.1
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• pp.57-62
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• 2008

The Warthin tumor is a benign neoplasm that occurs mostly in the parotid gland. The tumor frequently occurs in the tail of the parotid gland. A 75-year-old man was referred to Wonkwang dental hospital with a chief complaint of swelling on the right submandibular area. Numerous salivary stones were observed in the right submandibular gland on computed tomography (CT). And the two tumorous lesions were incidentally found in the parotid gland bilaterally. The tumorous lesions showed homogeneous enhancement on the CT and intermediate signal intensity on both T1- and T2-weighted magnetic resonance (MR) images. This tumorous lesions also showed contrast enhancement on fat suppressed T1 weighted MR images. We report common CT and MR features of this case of Warthin tumor in the parotid gland with literature review.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.25 no.1
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• pp.51-70
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• 1995

The purpose of this investigation was to compare the direct digital radiographic system with film-based digital imaging system using Ektaspeed and Ektaspeed Plus film with respect to image characteristics and detectability and evaluate the sensor noise with the use of subtraction method. Direct digital radiographic system which used was Sens-A-Ray system(Regam Medical Systems, Sundsvall, Sweden) and film-based digital imaging system was composed of Macintosh II ci computer, high resolution Sony XC-77 CCD camera and intraoral x-ray film(Kodak Ektaspeed film, Kodak Ektaspeed Plus film). Images were taken by using CCD sensor of Sens-A-Ray system, Ektaspeed film and Ektaspeed Plus film with variable exposure time(0.06s, 0.1s, 0.16s, 0.2s, 0.3s, 0.4s, 0.5s, 0.6s, O.8s, LOs), 5 times at each exposure time. And then ektaspeed films and ektaspeed plus films were digitized using CCD camera. Image groups were divided into 3 groups; Sens-A-Ray group(direct digital radiographic system), Ektaspeed group and Ektaspeed Plus group (film-based digital imaging system) They were assessed by the following three aspects; image density, image contrast and detectability and sensor noise of Sens-A-Ray system was also evaluated. The results were as follow : 1. S group showed higher density than E , EP group except at the low exposure time(p<0.01). 2. S group showed higher contrast than E,EP group except at the high exposure time(p<0.01). 3. All groups showed good detectability at the each proper exposure time. Lowest exposure time which shows maximum detectability in S,EP group(0.5s) was lower than that in E group(0.6s). 4. Sensor noise of Sens-A-Ray system generally increased according to exposure time. On the basis of the above results, it was considered that Sens-A-Ray system could show higher speed, higher contrast than Ektaspeed, Ektaspeed Plus film except at too high and low exposure time and the same detectability as the conventional intraoral film.

• Imaging Science in Dentistry
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• v.50 no.1
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• pp.23-30
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• 2020

Purpose: This study was conducted to assess the effectiveness of a metal artifact reduction (MAR) algorithm activated at different times during cone-beam computed tomography (CBCT) acquisition on the magnitude of artifacts generated by a zirconium implant. Materials and Methods: Volumes were obtained with and without a zirconium implant in a human mandible, using the OP300 Maxio unit. Three modes were tested: without MAR, with MAR activated after acquisition, and with MAR activated before acquisition. Artifacts were assessed in terms of the standard deviation (SD) of gray values and the contrast-to-noise ratio (CNR) in 6 regions of interest with different distances (10 to 35 mm, from the nearest to the farthest) and angulations(70° to 135°) from the implant region. Results: In the acquisitions without MAR, the regions closer to the implant(10 and 15mm) had a higher SD and lower CNR than the farther regions. When MAR was activated (before or after), SD values did not differ among the regions (P>0.05). The region closest to the implant presented a significantly lower CNR in the acquisitions without MAR than when MAR was activated after the acquisition; however, activating MAR before the acquisition did not yield significant differences from either of the other conditions. Conclusion: Both modes of MAR activation were effective in decreasing the magnitude of CBCT artifacts, especially when the effects of the artifacts were more noticeable.

• Journal of Korean society of Dental Hygiene
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• v.15 no.3
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• pp.523-529
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• 2015

Objectives: Oropharynx tumors(oral cancer), are caused by tobacco, alcohol consumption, and high-risk human papillomavirus(HPV) infection. Oral squamous cell carcinoma(OSCC) is the most common type of oral cancer and frequently arises from the mucosa of the oropharynx and oral cavity. Despite advances in the diagnosis and treatment(chemotherapy, radiotherapy, and surgery) of oral cancer, over the past two decades, the overall survival rates remains at about 60%. Methods: We pretreated HSC-2 cells with various doses of exposed the cells to eugenol and then we measured cell viability by MTT assay. Results: Cell proliferation was markedly inhibited after eugenol treatment compared to the control. The majority of HSC-2 cells in the control groups showed normal morphology with round regular nuclei. In contrast, apoptotic bodies were seen in the 0.5 mM, 1 mM, 2 mM group. However, the pretreatment with eugenol increased HSC-2 cells apoptosis according to dose-dependency. PI staining quantitatively confirmed the anti-apoptotic effects of propofol. The expression levels of cleaved caspase 3, and Bak significantly increased in HSC-2 cells. Conclusions: These findings indicate that eugenol could be a potential anti-cancer agent for human OSCC and provide valuable data for the development of a novel anticancer strategy.

• Phonetics and Speech Sciences
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• v.3 no.4
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• pp.33-43
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• 2011

The present study investigates supralaryngeal articulatory characteristics of denti-alveolar (coronal) stops /t, $t^h$, $t^*$/ and /n/ in /aCa/ context in Seoul Korean. An Electromagnetic Articulograph (EMA, Carstens) was used to explore kinematics of the consonants by examining the kinematic data of the tongue tip (the primary articulator for the coronal consonants), along with some additional supplementary position data of the tongue body, the tongue dorsum and the jaw. The results showed that the constriction duration was the most robust articulatory correlates of the three-way stop contrast with a pattern of /t/$t^h$/$t^*$/. The contrast was further reinforced by the tongue body position (higher for /$t^h$, $t^*$/) and the tongue tip opening displacement (less displaced for /$t^h$, $t^*$/). The articulation of /n/ was quite similar to that of the lenis /t/ in terms of the constriction duration, and it was different from the oral stops in that it was produced with larger tongue tip displacement and lower jaw position than the oral stops, indicating its weak articulatory nature. The results are also discussed in comparison with those of bilabial stops with implications that the three-way contrast may be kinematically expressed differently depending on the physiological constraints imposed on the primary articulator (the tongue tip versus the lips). The present study, therefore, provides new articulatory (kinematic) data of denti-alveolar consonants in Korean, and demonstrates that the three-way stops, that have been known to differ primarily in their laryngeal settings, are indeed produced with kinematic distinctions at the supralaryngeal level.