• Title/Summary/Keyword: Optimal design

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True Digestibility of Phosphorus in Different Resources of Feed Ingredients in Growing Pigs

  • Wu, X.;Ruan, Z.;Zhang, Y.G.;Hou, Y.Q.;Yin, Y.L.;Li, T.J.;Huang, R.L.;Chu, W.Y.;Kong, X.F.;Gao, B.;Chen, L.X.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.1
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    • pp.107-119
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    • 2008
  • To determine the true digestible phosphorus (TDP) requirement of growing pigs, two experiments were designed with the experimental diets containing five true digestible P levels (0.16%, 0.20%, 0.23%, 0.26% and 0.39%) and the ratio of total calcium to true digestible P (TDP) kept at 2:1. In Experiment 1, five barrows (Duroc${\times}$Landrace${\times}$Yorkshire) with an average initial body weight of 27.9 kg were used in a $5{\times}5$ Latin-square design to evaluate the effect of different dietary P levels on the digestibility and output of P and nitrogen. In Experiment 2, sixty healthy growing pigs (Duroc${\times}$Landrace${\times}$Yorkshire) with an average body weight (BW) of 21.4 kg were assigned randomly to one of the five dietary treatments (12 pigs/diet), and were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. The results indicated that the true digestibility of P increased (p<0.05) linearly with increasing dietary TDP level below 0.26%. The true P digestibility was highest (56.6%) when dietary TDP was 0.34%. Expressed as g/kg dry matter intake (DMI), fecal P output increased (p<0.05) linearly with increasing P input. On the basis of g/kg fecal dry matter (DM), fecal P output was lowest for Diet 4 and highest (p<0.05) for Diet 5. The apparent digestibility of crude protein (CP) did not differ (p>0.05) among the five diets, with the average nitrogen output of 12.14 g/d and nitrogen retention of 66% to 74% (p>0.05), which suggested that there was no interaction between dietary P and CP protein levels. During the 28-d experimental period of Experiment 2, the average daily gain (ADG) of pigs was affected by dietary TDP levels as described by Eq. (1): $y=-809,532x^4+788,079x^3-276,250x^2+42,114x-1,759$; ($R^2=0.99$; p<0.01; y = ADG, g/d; x = dietary TDP, %), F/G for pigs by Eq. (2): $y=3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2=0.99$; p<0.01; y = F/G; x = dietary TDP, %), and Total P concentrations in serum by Eq. (3): $y=-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ (R2 = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest F/G (1.07) and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet at a total Ca to TDP ratio of 2:1.

A Study for the Evaluation of Container Modules; The Technology of Korean Container Tree Production Model (한국형 컨테이너 조경수 생산기술로서 컨테이너 모듈의 성능 평가)

  • Jung, Yong-Jo;Lim, Byung-Eul;Oh, Jang-keun
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.5
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    • pp.59-67
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    • 2016
  • In landscape design by public institutions, although the costs and species of landscape trees stipulated by the Korean Public Procurement Service(PPS) are generally adhered to, the PPS regulations about planting trees with well-developed rootlets are almost entirely neglected. This study aimed to evaluate the performance of buried container modules, which are a new technology and product in landscape production that is able to reduce the defect rate while complying with regulations. To this end, this study measured rootlet density, rootlet development length, rootlet survival rate on excavation, and impairments of tree growth for 3 months after root pruning, and compared these variables for the container modules with those for trees that underwent root pruning in bare ground, and those that were cultivated in a container above ground. The results were as follows: First, the rootlet density was 88% for the trees in container modules, which was very high. Trees that underwent standard root pruning in bare ground had a somewhat lower density of 64%. Meanwhile, the trees that were cultivated in pots above ground died, invalidating measurement. Second, in terms of rootlet development and rootlet survival rate, the trees in container modules showed a mean length of 10.4cm, and 100% survival rate, indicating that there was no rootlet damage caused by excavation. For the trees that only underwent root pruning in bare ground, the mean length was 25.6cm and the rootlet survival rate was only half that of the trees in container modules, at 56%, demonstrating considerable damage. Rootlet development did not occur at all in the trees grown in pots. Third, the trees in container modules and those that underwent root pruning in bare ground did not show any deaths during the root pruning process, or any impairments such as stunted leaf growth. Conversely, the trees grown in pots nearly all died, and severe impairments of tree growth were observed. As shown by the results above, when we evaluated the performance of buried container modules, they showed the most outstanding performance of the three models tested in this study. The container modules prevent defects by stimulating early rooting in environments that with poor conditions for growth, or in trees that are not suited to the summer environment Therefore, it is expected that they would be an optimal means by which to enable compliance with rules such as the regulation presented by the PPS.

Design and Optimization of Pilot-Scale Bunsen Process in Sulfur-Iodine (SI) Cycle for Hydrogen Production (수소 생산을 위한 Sulfur-Iodine Cycle 분젠반응의 Pilot-Scale 공정 모델 개발 및 공정 최적화)

  • Park, Junkyu;Nam, KiJeon;Heo, SungKu;Lee, Jonggyu;Lee, In-Beum;Yoo, ChangKyoo
    • Korean Chemical Engineering Research
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    • v.58 no.2
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    • pp.235-247
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    • 2020
  • Simulation study and validation on 50 L/hr pilot-scale Bunsen process was carried out in order to investigate thermodynamics parameters, suitable reactor type, separator configuration, and the optimal conditions of reactors and separation. Sulfur-Iodine is thermochemical process using iodine and sulfur compounds for producing hydrogen from decomposition of water as net reaction. Understanding in phase separation and reaction of Bunsen Process is crucial since Bunsen Process acts as an intermediate process among three reactions. Electrolyte Non-Random Two-Liquid model is implemented in simulation as thermodynamic model. The simulation results are validated with the thermodynamic parameters and the 50 L/hr pilot-scale experimental data. The SO2 conversions of PFR and CSTR were compared as varying the temperature and reactor volume in order to investigate suitable type of reactor. Impurities in H2SO4 phase and HIX phase were investigated for 3-phase separator (vapor-liquid-liquid) and two 2-phase separators (vapor-liquid & liquid-liquid) in order to select separation configuration with better performance. The process optimization on reactor and phase separator is carried out to find the operating conditions and feed conditions that can reach the maximum SO2 conversion and the minimum H2SO4 impurities in HIX phase. For reactor optimization, the maximum 98% SO2 conversion was obtained with fixed iodine and water inlet flow rate when the diameter and length of PFR reactor are 0.20 m and 7.6m. Inlet water and iodine flow rate is reduced by 17% and 22% to reach the maximum 10% SO2 conversion with fixed temperature and PFR size (diameter: 3/8", length:3 m). When temperature (121℃) and PFR size (diameter: 0.2, length:7.6 m) are applied to the feed composition optimization, inlet water and iodine flow rate is reduced by 17% and 22% to reach the maximum 10% SO2 conversion.

Analysis of Flood Control Effect by Applying the Connecting Channel in Estuary Area Including the Confluence of Two Rivers (2개의 하천이 합류하는 하구역에서의 연결수로 통수능에 따른 홍수위저감효과 분석)

  • Kim, Sooyoung;Kim, Hyung-Jun;Yoon, Kwang Seok
    • Journal of Korea Water Resources Association
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    • v.48 no.12
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    • pp.1065-1075
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    • 2015
  • In the estuary where the structure such as river-mouth weir has been installed, the flow is developed very complicatedly due to river water from upstream, tide of the sea and floodgate operation. Especially, if basin outlets more than one exists in one estuary, the boundary conditions will be significantly more complex form. Saemangeum(SMG) project area in Korea is the most typical example. There are Mankyung river and Dongjin river in upstream. The water of them inflows into SMG project area. In the downstream, river flow was drained from inland to sea over the SMG sea dike through the sluice. The connecting channel was located between Mankyung and Dongjin basins. It functions not only as transportation by ship in ordinary period but also as flood sharing by sending flood flow to each other in flood period. Therefore, in order to secure the safety against flood, it is very important to understand the flood sharing capacity for connecting channel. In this study, the flood control effect was analyzed using numerical simulation. Delft3D was used to numerical simulation and simulated period was set up with neap tide, in which the maximum flood stage occurred due to poor drainage. Actually, three connecting channels were designed in land use plan of the SMG Master Plan, but they were simplified to a single channel for conciseness of analysis in this study. According to the results of numerical analysis, the water level difference between two basins was increased and the maximum flood stage at dike sluice was also upraised depending on decrease of conveyance. And the velocity induced by same water level difference was decreased when the conveyance became smaller. In certain conveyance above, there was almost no flood control effect. Therefore, if the results of this study are considered for design of connecting channel, it will be expected to draw the optimal conveyance for minimizing dredging construction cost while maximizing the flood control effect.

Effects of Dietary Concentrate Levels Based on Whole-Crop Barley Silage on Growth and Meat Quality in Growing Korean Black Goats (청보리 사일리지 급여 시에 농후사료 급여수준이 육성기 흑염소의 발육과 육질에 미치는 영향)

  • Hwang, Bo-Soon;Choi, Sun-Ho;Kim, Sang-Woo;Kim, Won-Ho;Son, Dong-Soo;Jo, Ik-Hwan
    • Journal of Animal Science and Technology
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    • v.50 no.4
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    • pp.527-534
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    • 2008
  • Effects of dietary concentrate levels based on whole-crop barley silage (BS) on development and meat quality in growing Korean black goats were examined. A total of 36 male goats with similar age and BW were equally allocated to dietary four treatments in a randomized complete block design. Dietary treatments included controls(rice straw ad libitum plus 2.0% concentrate BW-1), and BS ad libitum plus three increasing levels of concentrate BW-1(2.0, 1.5 and 1.0%, respectively), expressed as BS 2.0, BS 1.5 and BS 1.0, respectively. The trial was lasted for 5 months from 14th of May to 12th of October, 2007. At the end of trial, all animals were slaughtered to analyze carcass characteristics and meat quality. Average daily gain was significantly(p<0.05) higher for BS 1.5 and BS 2.0 treatments than for controls. Daily feed intakes for controls(689.3 g) were significantly(p<0.05) higher than those of BS 1.0(585.5 g), but they were significantly(p<0.05) lower than BS 2.0(734.3 g). Carcass and meat percentages were significantly (p<0.05) higher for BS 2.0 and BS 1.5 than for control and BS 1.0 treatments. Shear force and water-holding capacity was greater(p<0.05) for BS 2.0 and BS 1.5 than other treatments. On the basis of feeding whole-crop barley silage to Korean black goats, as dietary concentrate inclusion levels increased, sensory results showed to have a better tendency. In conclusion, it was estimated that the optimal level of dietary concentrates might be 1.5% BW-1, when diets based whole-crop barley silage were fed to growing Korean black goats for their improvements of growth and meat quality.

Method Development for the Profiling Analysis of Endogenous Metabolites by Accurate-Mass Quadrupole Time-of-Flight(Q-TOF) LC/MS (LC/TOFMS를 이용한 생체시료의 내인성 대사체 분석법 개발)

  • Lee, In-Sun;Kim, Jin-Ho;Cho, Soo-Yeul;Shim, Sun-Bo;Park, Hye-Jin;Lee, Jin-Hee;Lee, Ji-Hyun;Hwang, In-Sun;Kim, Sung-Il;Lee, Jung-Hee;Cho, Su-Yeon;Choi, Don-Woong;Cho, Yang-Ha
    • Journal of Food Hygiene and Safety
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    • v.25 no.4
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    • pp.388-394
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    • 2010
  • Metabolomics aims at the comprehensive, qualitative and quantitative analysis of wide arrays of endogenous metabolites in biological samples. It has shown particular promise in the area of toxicology and drug development, functional genomics, system biology and clinical diagnosis. In this study, analytical technique of MS instrument with high resolution mass measurement, such as time-of-flight (TOF) was validated for the purpose of investigation of amino acids, sugars and fatty acids. Rat urine and serum samples were extracted by selected each solvent (50% acetonitrile, 100% acetonitrile, acetone, methanol, water, ether) extraction method. We determined the optimized liquid chromatography/time-of-flight mass spectrometry (LC/TOFMS) system and selected appropriated columns, mobile phases, fragment energy and collision energy, which could search 17 metabolites. The spectral data collected from LC/TOFMS were tested by ANOVA. Obtained with the use of LC/TOFMS technique, our results indicated that (1) MS and MS/MS parameters were optimized and most abundant product ion of each metabolite were selected to be monitorized; (2) with design of experiment analysis, methanol yielded the optimal extraction efficiency. Therefore, the results of this study are expected to be useful in the endogenous metabolite fields according to validated SOP for endogenous amino acids, sugars and fatty acids.

Development of Optimal Seed Production Methods Using Domestic Rye Cultivar in Central and North Area of Korea (중·북부지역에서 국내육성 호밀품종의 채종방법)

  • Han, Ouk-Kyu;Song, Ju-Hee;Ku, Ja-Hwan;Kim, Dea-Wook;Kwon, Young-Up;Lee, Yu-Young;Park, Chang-Hwan;Kweon, Soon-Jong;Ahn, Jong-Woong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.38 no.1
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    • pp.44-52
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    • 2018
  • This experiment was conducted at Suwon, Korea from 2013 to 2015. The objective of this study was to establish the optimum seeding rate, and to clarify the nitrogen fertilizer level for rye seed production in central and north area of Korea. We used Korean rye cultivar 'Gogu' for this test. We employed a split-plot design with three replications. The main plots were designed by three seeding levels (3, 5 and $7kg\;10a^{-1}$), but other sub-plots were randomly seeded. The plots were treated with three different nitrogen fertilizer levels (3, 6 and $9kg\;10a^{-1}$). The percentage of productive tiller, number of grain per spike, fertility rate, 1 liter weight, and 1000-grain weight decreased as seeding rate increased from $3kg\;10a^{-1}$ to $7kg\;10a^{-1}$, whereas the number of spike per $m^2$ increased. Therefore the grain yields of rye had less of an effect by increasing seeding rate. There was an increase in number of spike per $m^2$, number of grain per spike, and fertility rate as nitrogen fertilizer level increased from $3kg\;10a^{-1}$ to $9kg\;10a^{-1}$, but grain yields significantly not affected by the interaction of seeding rate ${\times}$ nitrogen fertilizer levels. However, the best seeding rate and nitrogen fertilizer level for rye seed production were 5 kg and $5{\sim}6kg\;10a^{-1}$, respectively, considering seed and fertilizer reduction and the prevention of pollution by excess fertilization.

Optimization of spray drying conditions of soft persimmon and milk mixture using response surface methodology (반응표면분석법을 이용한 홍시와 우유혼합물의 최적 분무건조 조건)

  • Park, Mi-Jeong;Kim, Sang-Bum;Kim, Sook-Jin;Kim, Kyung-Mi;Choi, Song-Yi;Chang, Mi;Kim, Gi-Chang
    • Food Science and Preservation
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    • v.24 no.7
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    • pp.957-964
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    • 2017
  • The purpose of this study was to determine the optimum spray drying conditions of soft persimmon latte using response surface methodology that is a statistical procedure used for optimization studies. A central composite design was applied to investigate the effects of independent variables, inlet temperature ($X_1$), air flow rate ($X_2$), and feed flow rate ($X_3$), on responses such as yield, water absorption index, and total phenolic compounds. Statistical analysis revealed that independent variables significantly affected all the responses. A maximum yield of 8.11 g was obtained at $90^{\circ}C$ of $X_1$, 51.82 mL/min of $X_2$ and 7.00 mL/min of $X_3$. A minimum water absorption index of 0.58 was obtained at $101^{\circ}C$ of $X_1$, 60.00 mL/min of $X_2$ and 17.00 mL/min of $X_3$. A maximum total phenolic compounds of $298.02{\mu}g/mL$ was obtained at $90^{\circ}C$ of $X_1$, 43.33 mL/min of $X_2$ and 17.00 mL/min of $X_3$. In conclusion, the best spray drying conditions were as follows: $X_1$, $90^{\circ}C$; $X_2$, 53 mL/min; $X_3$, 17 mL/min. Under those optimal conditions, the powder's yield (7.46 g), water absorption index (0.54), and the content of total phenolic compounds ($294.75{\mu}g/mL$) were estimated.

Assessment of statistical errors of articles published in the Journal of the Korean Academy of Prosthodontics: 2006 - 2010 (대한치과보철학회지에서 볼 수 있는 통계적 오류의 고찰(2006 - 2010))

  • Kang, Dong-Wan;Seo, Yunam;Oh, Nam-Sik;Lim, Hoi-Jeong
    • The Journal of Korean Academy of Prosthodontics
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    • v.50 no.4
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    • pp.258-270
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    • 2012
  • Purpose: Use of inappropriate statistical methods may lead to incorrect conclusions and a waste of valuable resources. The goal of this study was to assess the frequency and the types of several common statistical errors in the published articles of the Journal of the Korean Academy of Prosthodontics (JKAP) for a 5-year period. Materials and methods: Of 336 articles in the JKAP published from 2006 to 2010, 255 articles using statistics were reviewed and classified by statistical method and year. The frequency and types of the statistical methods were examined, and the statistical errors were evaluated by the appropriateness of the experimental design, assumption check, independent outcomes, proper sample size and suitable use of statistical method. Statistical guidelines were completed based on the appropriateness. Results: Of the 255 articles using statistics, 193 articles (75.9%) used inferential statistics and 153 articles used SPSS statistical software (60.0%). Of the articles using inferential statistics, the three most frequently used statistical methods were ANOVA (41.5%), t-test (20.0%), and the nonparametric method (16.9%). The average rate of statistical errors was 61.2 percent, similar to the rate reported by several studies completed for the medical journal. Conclusion: After the whole analysis of the difference among the groups, post-hoc tests for the pairwise comparisons are required. The optimal sample size calculation is an essential part of this study protocol. To minimize the occurrence of statistical errors, statistical guidelines were developed according to each statistical test procedure and will contribute to the academic improvement in the JKAP.

Optimization of Hot-Water Extraction Conditions for Preparation of Polyphenol and Gallic Acid from Acorn (도토리의 Polyphenol 및 Gallic Acid 성분의 열수 추출조건 최적화)

  • Kim, Seong-Ho;Lee, Jin-Man
    • Food Science and Preservation
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    • v.15 no.1
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    • pp.58-65
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    • 2008
  • The Acorn (Quercus acutissima CARRUTHERS), which contains a large quantity of tannin, should be developed as a processed food as the acorn is rich in natural antioxidants and other valuable components. Accordingly, acorn extraction conditions for polyphenol and gallic acid (both antioxidants) were investigated by response surface methodology. The content of polyphenols were determined under 16 different extraction conditions based upon a central composite design. The parameters varied over $30-70^{\circ}C$ of extraction temperature, 1-5 h of extraction time, and 5-25 mL/g of solvent ratio, Gallic acid extraction was optimal at $60-100^{\circ}C$ extraction temperature, 1-5 h of extraction time, and 5-25 mL/g of solvent ratio, Epicatechin content was highest at $56.77^{\circ}C$, 4.16 hand 22.38 mL/g. Catechin content was highest at $52.37^{\circ}C$, 2h and 23.59 mL/g. The maximum catechin content was $91.30{\mu}g/mL$. Epigallocatechin content was influenced by extraction temperature and time. The maximum epigallocatechin content was $1,066.56{\mu}g/mL$ at $61.42^{\circ}C$, 4.17h, and 9.25 mL/g. The maximum value of epicatechingallate content was $125.39{\mu}g/mL$ at $47.72^{\circ}C$, 3.04h, and 24.93mL/g. Epigallocatechingallate content was influenced principally by solvent ratio and the maximum content was $61.38{\mu}g/mL$ at $48.11^{\circ}C$, 2.96h, and 24.95mL/g. The total polyphenol content was maximal at $1,332.75{\mu}g/mL$, after extraction at $61.50^{\circ}C$, 4.24h, at 9.71mL/g. The higher the extraction temperature and the longer the extraction time, the greater the polyphenol content. Gallic acid content was highest, the maximal level was $30.51{\mu}g/mL$ after $65.84^{\circ}C$, 1.65h at 17.17 mL/g, and this was influenced principally by extraction time and solvent ratio.