• Journal of Embryo Transfer
• /
• v.25 no.4
• /
• pp.251-258
• /
• 2010

In the present study, effects of concentration and time of culture in presence of roscovitine on nuclear maturation and meiotic spindle configuration, chromosomal alignment were examined in porcine oocytes. In experiment 1, porcine cumulus oocyte complexes (COCs) were cultured at $39^{\circ}C$ in a 5% $CO_2$ atmosphere in North Carolina State University 23 (NCSU-23) supplemented with 25, 50, 75 or $100\;{\mu}M$ roscovitine for 22 h and then were cultured for additional 22 h after removal of roscovitine. Nuclear maturation and morphology of the meiotic spindle and chromosomal alignment were examined to determine the optimal concentration of roscovitine in oocyte maturation. In experiment 2, COCs were cultured in NCSU-23 supplemented with $50\;{\mu}M$ roscovitine for 17, 20, 27 or 42 h and then an additional 22 h without roscovitine was followed to determine the optimal time of culture. The optimal concentration of roscovitine to arrest and resume meiosis of porcine oocyte was $50\;{\mu}M$ by examining nuclear status (p<0.05) and normal spindle and chromosome configuration. The optimal time of culture in presence of roscovitine to arrest meiosis of porcine oocyte was 17 h (p<0.05), although MII rates and normal morphology of the meiotic spindle and chromosomal alignment were not significantly different among various times of culture. In conclusion, the optimal concentration and time of culture in presence of roscovitine to arrest porcine oocytes are $50\;{\mu}M$ and 17 h, respectively.

• IE interfaces
• /
• v.11 no.3
• /
• pp.23-40
• /
• 1998

In this paper, a method to determine the optimal configuration of operating policies in an integrated-automated manufacturing system using the Taguchi method and computer simulation experiments is presented. An integrated-automated manufacturing system called direct-input-output manufacturing system(DIOMS) is described. We only consider the operational aspect of the DIOMS. Four operating policies including input sequencing control, dispatching rule for the storage/retrieval(S/R) machine, machine center-based part type selection rule, and storage assignment policy are treated as design factors. The number of machine centers, the number of part types, demand rate, processing time and the rate of each part type, vertical and horizontal speed of the S/R machine, and the size of a local buffer in the machine centers are considered as noise factors in generating various manufacturing system environment. For the performance characteristics, mean flow time and throughput are adopted. A robust design experiment with inner and outer orthogonal arrays are conducted by computer simulation, and an optimal configuration of operating policies is presented which consists of a combination of the level of each design factor. The validity of the optimal configurations is investigated by comparing their signal-to-noise ratios with those obtained with full factorial designs.

• Smart Structures and Systems
• /
• v.30 no.6
• /
• pp.583-599
• /
• 2022

In this paper, a multi-objective wireless sensor network configuration optimization method is proposed. The proposed method aims to determine the optimal information and lifespan wireless sensor network for structural health monitoring of large-scale infrastructures. In particular, cluster-based wireless sensor networks with multi-type of sensors are considered. To optimize the lifetime of the wireless sensor network, a cluster-based network optimization algorithm that optimizes the arrangement of cluster heads and base station is developed. On the other hand, based on the Bayesian inference, the uncertainty of the estimated parameters can be quantified. The coefficient of variance of the estimated parameters can be obtained, which is utilized as a holistic measure to evaluate the estimation accuracy of sensor configurations with multi-type of sensors. The proposed method provides the optimal wireless sensor network configuration that satisfies the required estimation accuracy with the longest lifetime. The proposed method is illustrated by designing the optimal wireless sensor network configuration of a cable-stayed bridge and a space truss.

• Journal of the Korean Data and Information Science Society
• /
• v.14 no.2
• /
• pp.237-245
• /
• 2003

MDS(multi-dimensional scaling) for preference data is a graphical tool which usually figures out how consumers recognize, evaluate certain products. This article is mainly concerned with an optimal scaling for MDS when target configuration is available. Rotation of axis and SUR(seemingly unrelated regression) methods are employed to get a new configuration which is obtained as close to the target as we can. Methodologies developed here are also illustrated via a real data set.

• International Journal of Naval Architecture and Ocean Engineering
• /
• v.7 no.6
• /
• pp.1044-1055
• /
• 2015

DPCap analysis can assist in determining the maximum environmental forces the DP system can counteract for a given heading. DPCap analysis results are highly affected by the thrust forces provided by the thrust system which consists of several kinds of thrusters. The thrust forces and moment are determined by the maximum thrust of the thrusters as well as the thruster configuration. In this paper, a novel local optimization of thruster configuration based on a synthesized positioning capability criterion is proposed. The combination of the discrete locations of the thrusters forms the thruster configuration and is the input, and the synthesized positioning capability is the output. The quantified synthesized positioning capability of the corresponding thruster configuration can be generated as the output. The optimal thruster configuration is the one which makes the vessel has the best positioning capability. A software program was developed based on the present study. A local optimization of thruster configuration for a supply vessel was performed to demonstrate the effectiveness and efficiency of the program. Even though the program cannot find the global optimal thruster configuration, its high efficiency makes it essentially practical in an engineering point. It may be used as a marine research tool and give guidance to the designer of the thrust system.

• Earthquakes and Structures
• /
• v.14 no.1
• /
• pp.1-10
• /
• 2018

Seismic retrofitting of existing buildings and design of earth-quake resistant buildings are important issues associated with earthquake-prone zones. Use of metallic-yielding dampers as an energy dissipation system is an acceptable method for controlling damages in structures and improving their seismic performance. In this study, the optimal distribution of dampers for reducing the seismic response of steel frames with multi-degrees freedom is presented utilizing the uniform distribution of deformations. This has been done in a way that, the final configuration of dampers in the frames lead to minimum weight while satisfying the performance criteria. It is shown that such a structure has an optimum seismic performance, in which the maximum structure capacity is used. Then the genetic algorithm which is an evolutionary optimization method is used for optimal arrangement of the steel dampers in the structure. In continuation for specifying the optimal accurate response, the local search algorithm based on the gradient concept has been selected. In this research the introduced optimization methods are used for optimal retrofitting in the moment-resisting frame with inelastic behavior and initial weakness in design. Ultimately the optimal configuration of dampers over the height of building specified and by comparing the results of the uniform deformation method with those of the genetic algorithm, the validity of the uniform deformation method in terms of accuracy, Time Speed Optimization and the simplicity of the theory have been proven.

• International Journal of Automotive Technology
• /
• v.8 no.6
• /
• pp.791-798
• /
• 2007

The hydraulic hybrid vehicle(HHV) is an application of hydrostatic transmission technology to improve vehicle fuel economy and emissions. A relatively lower energy density of hydraulic accumulator and complicated coordinating operations between two power sources require a special energy management strategy to maximize the fuel saving potential. This paper presents a new type of configuration for parallel HHV to minimize the disadvantages of the hydraulic accumulator, as well as a methodology for developing an energy management strategy tailored specially for PHHV. Based on an analysis of the optimal energy distribution between two power sources over a representative urban driving cycle with a Dynamic Programming(DP) algorithm, a fuzzy-based optimal torque management strategy is designed and developed to control the torque distribution. Simulation results demonstrates that the optimal torque management strategy maximizes the advantages of this hybrid type of configuration, and the high power density characteristics of hydraulic technology effectively improve the robustness of the energy management strategy and fuel economy of the PHHV.

• Journal of Institute of Control, Robotics and Systems
• /
• v.11 no.3
• /
• pp.254-261
• /
• 2005

Time-optimal performances are analyzed in the sense of inner loop. A varying-time sharing thrusting logic is suggested as a new sequential paired thrusting logic for fast maneuvers of satellites with coupled thruster configuration. Its time-optimal maneuvering performance is compared with two conventional thrusting logics: separate thrusting logic and constant-time sharing sequential paired thrusting logic. It is found that the newly suggested varying-time sharing thrusting logic can be easily implemented by adjusting the conventional constant-time logic with its thrust on-time, while it can reduce the maneuvering time enormously as much as the separate thrusting logic. The performance of the logic is simulated on the agile maneuvering spacecraft model KOMPSAT-II.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.18 no.2
• /
• pp.129-136
• /
• 2006

Optimal design of an air-to-liquid finned plate heat exchanger is considered theoretically in this study. Based on existing correlations for the pressure loss and the heat transfer in channel flows, the optimal configuration of the plate heat exchanger including the optimal plate pitch and the optimal fin pitch is obtained to maximize the heat transfer within the limit of the pressure drop for a given flow depth of the plate heat exchanger. It is found that the optimal fin pitch is about one ninth of the optimal plate pitch. In the optimal configuration, the flow and thermal condition in the channels is just at the boundary between the laminar developing and laminar fully developed states. It is also found when reducing the flow depth of plate heat exchangers for compactness, the heat transfer performance can be maintained exactly the same if the geometric parameters such as the plate thickness, plate pitch, fin thickness, and fin pitch are reduced proportional to the square root of the flow depth as long as the flow keeps laminar within the heat exchangers.

• Journal of Communications and Networks
• /
• v.18 no.1
• /
• pp.50-64
• /
• 2016

Nowadays, smart meter (SM) technology is widely effectively used. In addition, power allocation (PA) and channel selection (CS) are considered problems with many proposed approaches. In this paper, we will suggest a specific scenario for an SM configuration system and show how to solve the optimization problem for transmission between SMs and the data concentrator unit (DCU), the center that collects the data from several SMs, via simulation. An efficient CS with PA scheme is proposed in the TV white space system, which uses the TV band spectrum. On the basic of the optimal configuration requirements, SMs can have a transmission schedule and channel selection to obtain the optimal efficiency of using spectrum resources when transmitting data to the DCU. The optimal goals discussed in this paper are the maximum capacity or maximum channel efficiency and the maximum allowable power of the SMs used to satisfy the quality of service without harm to another wireless system. In addition, minimization of the interference to the digital television system and other SMs is also important and needs to be considered when the solving coexistence scenario. Further, we propose a process that performs an interference analysis scheme by using the spectrum engineering advanced Monte Carlo analysis tool (SEAMCAT), which is an integrated software tool based on a Monte-Carlo simulation method. Briefly, the process is as follows: The optimization process implemented by genetic evolution optimization engines, i.e., a genetic algorithm, will calculate the best configuration for the SM system on the basis of the interference limitation for each SM by SEAMCAT in a specific configuration, which reaches the solution with the best defined optimal goal satisfaction.