• Title/Summary/Keyword: Optimal TSR

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Simulation of Cardiovascular System for an Optimal Sodium Profiling in Hemodialysis

  • Lim, K.M.;Min, B.G.;Shim, E.B.
    • International Journal of Vascular Biomedical Engineering
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    • v.2 no.2
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    • pp.16-26
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    • 2004
  • The object of this study is to develop a mathematical model of the hemodialysis system including the mechanism of solute kinetics, water exchange and also cardiovascular dynamics. The cardiovascular system model used in this study simulates the short-term transient and steady-state hemodynamic responses such as hypotension and disequilibrium syndrome (which are main complications to hemodialysis patients) during hemodialysis. It consists of a 12 lumped-parameter representation of the cardiovascular circulation connected to set-point models of the arterial baroreflexes, a kinetic model (hemodialysis system model) with 3 compartmental body fluids and 2 compartmental solutes. We formulate mathematically this model in terms of an electric analog model. All resistors and most capacitors are assumed to be linear. The control mechanisms are mediated by the information detected from arterial pressoreceptors, and they work on systemic arterial resistance, heart rate, and systemic venous unstressed volume. The hemodialysis model includes the dynamics of urea, creatinine, sodium and potassium in the intracellular and extracellular pools as well as fluid balance equations for the intracellular, interstitial, and plasma volumes. Model parameters are largely based on literature values. We have presented the results on the simulations performed by changing some model parameters with respect to their basal values. In each case, the percentage changes of each compartmental pressure, heart rate (HR), total systemic resistance (TSR), ventricular compliance, zero pressure filling volume and solute concentration profiles are represented during hemodialysis.

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A Comparative Study on the Selection of Transportation Routes and Multipath Establishment of Automotive Parts from Korea to Europe (한국-유럽 국내 자동차부품의 운송루트 선정과 다중경로 구축에 관한 비교연구)

  • Kim, Yong-Kuk;Park, Keun-Sik;Kim, Jun-Seung
    • Korea Trade Review
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    • v.44 no.6
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    • pp.303-325
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    • 2019
  • The purpose of this study is to determine optimal transportation routes through the comparison of Korean - European transportation routes of automotive parts and to suggest information that can be utilized in Korea - Europe trade activities or trade route selection by establishing multipath. This study analyzed the direct transportation cost, inventory cost, and warehouse inventory cost of the sea and TSR / TCR railroad transport based on characteristics of automotive parts logistics and multimodal transportation. Also, this study identifies the most effective transportation route from the viewpoint of total logistics cost. In addition to the economic factors, we conducted an in-depth analysis through interviews with corporate executives to identify the importance of the factors with the behavioral factors, and the reliability was further secured through interviews. Through this study, it is possible to understand various aspects of international logistics by analyzing the factors of transportation choice in terms of economic and behavioral perspectives concurrently by differentiating from existing research.

Optimal flammability and thermal buckling resistance of eco-friendly abaca fiber/ polypropylene/egg shell powder/halloysite nanotubes composites

  • Saeed Kamarian;Reza Barbaz-Isfahani;Thanh Mai Nguyen Tran;Jung-Il Song
    • Advances in nano research
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    • v.16 no.2
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    • pp.127-140
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    • 2024
  • Upon direct/indirect exposure to flame or heat, composite structures may burn or thermally buckle. This issue becomes more important in the natural fiber-based composite structures with higher flammability and lower mechanical properties. The main goal of the present study was to obtain an optimal eco-friendly composite system with low flammability and high thermal buckling resistance. The studied composite consisted of polypropylene (PP) and short abaca fiber (AF) with eggshell powder (ESP) and halloysite clay nanotubes (HNTs) additives. An optimal base composite, consisting of 30 wt.% AF and 70 wt.% PP, abbreviated as OAP, was initially introduced based on burning rate (BR) and the Young's modulus determined by horizontal burning test (HBT) and tensile test, respectively. The effects of adding ESP to the base composite were then investigated with the same experimental tests. The results indicated that though the BR significantly decreased with the increase of ESP content up to 6 wt.%, it had a very destructive influence on the stiffness of the composite. To compensate for the damaging effect of ESP, small amount of HNT was used. The performance of OAP composite with 6 wt.% ESP and 3 wt.% HNT (OAPEH) was explored by conducting HBT, cone calorimeter test (CCT) and tensile test. The experimental results indicated a 9~23 % reduction in almost all flammability parameters such as heat release rate (HRR), total heat released (THR), maximum average rate of heat emission (MARHE), total smoke released (TSR), total smoke production (TSP), and mass loss (ML) during combustion. Furthermore, the combination of 6 wt.% ESP and 3 wt.% HNT reduced the stiffness of OAP to an insignificant amount by maximum 3%. Moreover, the char residue analysis revealed the distinct differences in the formation of char between AF/PP and AF/PP/ESP/HNT composites. Afterward, dilatometry test was carried out to examine the coefficient of thermal expansion (CTE) of OAP and OAPEH samples. The obtained results showed that the CTE of OAPEH composite was about 18% less than that of OAP. Finally, a theoretical model was used based on first-order shear deformation theory (FSDT) to predict the critical bucking temperatures of the OAP and OAPEH composite plates. It was shown that in the absence of mechanical load, the critical buckling temperatures of OAPEH composite plates were higher than those of OAP composites, such that the difference between the buckling temperatures increased with the increase of thickness. On the contrary, the positive effect of CTE reduction on the buckling temperature decreased by raising the axial compressive mechanical load on the composite plates which can be assigned to the reduction of stiffness after the incorporation of ESP. The results of present study generally stated that a suitable combination of AF, PP, ESP, and HNT can result in a relatively optimal and environmentally friendly composite with proper flame and thermal buckling resistance with no significant decline in the stiffness.