• Title/Summary/Keyword: Optical path-length

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Development of a Real-time Medical Imaging System Combined with Laser Speckle Contrast Imaging and Fluorescence Imaging (형광과 레이저 스펙클 대조도 이미징을 결합한 실시간 의료영상 시스템 개발)

  • Shim, Min Jae;Kim, Yikeun;Ko, Taek Yong;Choi, Jin Hyuk;Ahn, Yeh-Chan
    • Journal of Biomedical Engineering Research
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    • v.42 no.3
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    • pp.116-124
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    • 2021
  • It is important to differentiate between the target tissue (or organ) and the rest of the tissue before incision during surgery. And when it is necessary to preserve the differentiated tissues, the blood vessels connected to the tissue must be preserved together. Various non-invasive medical imaging methods have been developed for this purpose. We aimed to develop a medical imaging system that can simultaneously apply fluorescence imaging using indocyanine green (ICG) and laser speckle contrast imaging (LSCI) using laser speckle patterns. We designed to collect images directed to the two cameras on a co-axial optical path and to compensate equal optical path length for two optical designs. The light source used for fluorescence and LSCI the same 785 nm wavelength. This system outputs real-time images and is designed to intuitively distinguish target tissues or blood vessels. This system outputs LSCI images up to 37 fps through parallel processing. Fluorescence for ICG and blood flow in animal models were observed throughout the experiment.

GPU-based Monte Carlo Photon Migration Algorithm with Path-partition Load Balancing

  • Jeon, Youngjin;Park, Jongha;Hahn, Joonku;Kim, Hwi
    • Current Optics and Photonics
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    • v.5 no.6
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    • pp.617-626
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    • 2021
  • A parallel Monte Carlo photon migration algorithm for graphics processing units that implements an improved load-balancing strategy is presented. Conventional parallel Monte Carlo photon migration algorithms suffer from a computational bottleneck due to their reliance on a simple load-balancing strategy that does not take into account the different length of the mean free paths of the photons. In this paper, path-partition load balancing is proposed to eliminate this computational bottleneck based on a mathematical formula that parallelizes the photon path tracing process, which has previously been considered non-parallelizable. The performance of the proposed algorithm is tested using three-dimensional photon migration simulations of a human skin model.

Focal Length Measurement System for Camera Lens using the MTF (MTF 방법에 의한 카메라 렌즈 초점 자동 측정 시스템 개발)

  • 이석원;이동성;박희재;문호균;김영식
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1996.04a
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    • pp.264-270
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    • 1996
  • In this paper, a computer automated system has been developed for measuring the focal length of camera lens using the MTF(Modurar Transfer Function) based on the signal processing around a line CCD and autocollimator. An optical Path for the focal length measurement system has been designed around thelight sourec, collimator, camera, mirror and the line CCD. The eyepiece of the collimator is replaced byline CCD, and the mirror is moved along the focal axis by a PC driven step motor. An efficient method has been designed for finding the optimum MTF value for the focal length based on the least squares approach. The developed system is fullycomputer automated: signal transmission to and from the camera, MTF evaluation based on the line CCD, step motor contorl, etc. The developed system has been applied to a practical camera manufacturing process and demonstrated its performance

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High resolution heterodyne interferometric technique with AOM for measuring the thermal expansion (음향광변조기를 이용한 고분해능의 헤테로다인 간섭식 열팽창 측정기술)

  • 최병일;이상현;김종철;임동건
    • Korean Journal of Optics and Photonics
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    • v.13 no.6
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    • pp.530-536
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    • 2002
  • The accurate measurements of thermal expansion coefficients is one of the most important techniques required not only in material science but also in industries. A high precision interferometric dilatometer, using acoustic optical modulator, has been constructed and its performance has been tested. The system consists of a double-path optical heterodyne interferometer and a radiant heating furnace. This provides highly accurate length measurement, and allows rapid heating and cooling method for the specimen. A three longitudinal mode frequency stabilized He-Ne laser, using the secondary beat frequency, is constructed. Its stability is found to be $5{\times}10^{-9}$. The uncertainty in the length measurement is estimated to be of nanometer order in the range between room temperature to 1100 K.

Growth Characteristics of Ultrahigh-density Microalgal Cultures

  • Richmond, Amos
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.8 no.6
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    • pp.349-353
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    • 2003
  • The physiological characteristics of cultures of very high cell mass (e.g. 10g cell mass/L), termed“ultrahigh cell density cultures”is reviewed. A close relationship was found between the length of the optical path (OP) in flat-plate reactors and the optimal cell density of the culture as well as its areal (g m$\^$-2/ day$\^$-1/) productivity. Cell-growth inhibition (GI) unfolds as culture density surpasses a certain threshold. If it is constantly relieved, a 1.0cm OP reactor could produce ca. 50% more than reactors with longer OP, e.g. 5 or 10cm. This unique effect, discovered by Hu et al. [3], is explained in terms of the relationships between the frequency of the light-dark cycle (L-D cycle), cells undergo in their travel between the light and dark volumes in the reactor, and the turnover time of the photosynthetic center (PC). In long OP reactors (5cm and above) the L-D cycle time may be orders of magnitude longer than the PC turnover time, resulting in a light regime in which the cells are exposed along the L-D cycle, to long, wasteful dark periods. In contrast, in reactors with an OP of ca. 1.0 cm, the L-D cycle frequency approaches the PC turnover time resulting in a significant reduction of the wasteful dark exposure time, thereby inducing a surge in photosynthetic efficiency. Presently, the major difficulty in mass cultivation of ultrahigh-density culture (UHDC) concerns cell growth inhibition in the culture, the exact nature of which is awaiting detailed investigation.

Enhanced UV-Visible Absorbance Detection in Capillary Electrophoresis Using Modified T-Shaped Post-Column Flow Cell

  • Lim, Kwan-Seop;Kim, Su-Hyeon;Hahn, Jong-Hoon
    • Bulletin of the Korean Chemical Society
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    • v.23 no.2
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    • pp.295-300
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    • 2002
  • The construction of the T-shaped post-column flow cell has been changed to enhance the practicability as a UV-visible absorbance detector for capillary electrophoresis. In this new design, a rectangular cube-shaped inner structure is employed, which completely fits the outer rectangular tubing. This arrangement has greatly facilitated the fabrication of the T-cells. In addition, the volume for the auxiliary flow has been dramatically reduced down to 300 ${\mu}L$, and its volume flow rate is optimized at 4.2 ${\mu}L$/min. The short optical path length in the sheath flows (500 ${\mu}m$ on each side) minimizes background absorption, and thus enhances its performance in low-UV wavelengths. We have optimized the auxiliary flow rate at 50 ${\mu}m$/s, so that migration times are insensitive to the flow rate. This optimization has improved repeatabilities in migration times and peak heights. A double-beam detection scheme using a pair of photodiodes is employed to increase the signal-to-noise ratio.

AN OPTICAL FIBER FEED LITTROW-MOUNTED SPECTROMETER (광섬유 피드 리트로마운트형 분광계)

  • Bae, J.H.;Song, J.W.;Yoon, T.S.
    • Publications of The Korean Astronomical Society
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    • v.27 no.3
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    • pp.87-93
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    • 2012
  • A low-dispersion fiber feed Littrow-mounted grating spectrometer for education was designed and fabricated. The dispersion element is a reflective type blazed grating Edmundoptics NT 46-075 (spatial frequency 600 lines/mm, dimension $30mm{\times}30mm$, blazed angle 8.6 degree). The optical fiber coupler module for optical guiding from telescope to spectrometer is composed of a multi-mode FC connector - FC connector optical fiber patch cord (core/cladding diameter $50{\mu}m/125{\mu}m$) and two 1.25" throw-tube couplers. The lens for collimating and imaging is a general purpose focal length 50 mm camera lens (f/1.8). The device for optical path control is a rectangular prism (size $25mm{\times}25mm$). The imaging camera sensor is a Meade DSI Pro 2 CCD sensor (black and white, $752{\times}582$ pixels and pixel size $8.3{\mu}m{\times}8.6{\mu}m$). Softwares for data logging and analysis consist of Meade Autostar Suite, NIH imagej and Vernier Logger Pro 3. The wavelength coverage range of the spectrometer is 205 nm at central wavelength 550 nm. The wavelength resolution is 1.7 nm.

Effect of Glass Frit in $TiO_2$ Electrode for DSSCs (Glass Frit을 이용한 염료감응 태양전지의 광 특성 연구)

  • Kim, Jongwoo;Jeon, Jaeseung;Kim, Dongsun;Hwang, Seongjin;Kim, Hyungsun
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.75.1-75.1
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    • 2010
  • Dye sensitized solar cells(DSSCs) have been extensively studied due to their various advantages such as low production cost, colorful design, and eco-friendly process. Long optical path length is one of the most effective method to improve light harvest efficiency for DSSCs. Multi-layered $TiO_2$ nano-structured film with scattering layer has been studied to generate scattering effect by many researchers. It was expected that the difference of refractive index between $TiO_2$ particles and glass frit would generate the light scattering effect and provide the long optical path length. Therefore, to enhance the scattering effect, the frits of $Bi_2O_3-B_2O_3$-ZnO glass system that has the different refractive index were added to $TiO_2$ pastes in this study. First of all, the absorbance and haze factor of $TiO_2$ electrode with dyes and the refractive index of glass frit and $TiO_2$ were measured, respectively. To study the effect of frits, the efficiencies of DSSCs added glass frit and without glass frit were compared. Our results showed slightly higher efficiency with the different absorbance and haze factor of $TiO_2$ and glass frit. It was considered that the light scattering effect would be improved with adding frits to $TiO_2$ paste. Our preliminary studies will be useful for increasing efficiency of DSSCs.

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2-D/3-D Combined Algorithm for Automatic Solder Paste Inspection (솔더 페이스트 자동검사를 위한 2-D/3-D 복합 알고리즘)

  • 조상현;이상윤;임쌍근;최흥문
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.05a
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    • pp.173-176
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    • 2002
  • In this paper, we present the combined 2-D and 3-D algorithms for automatic solder paste inspection. For automatic inspection, optical system for the combined inspection and driving unit is made. One-pass run length algorithm that has fast and efficient memory space is applied to the input image fur extracting solder paste patterns. The path of probe movement is then calculated for an automatic inspection. For a fast 3-D inspection, the phase shift algorithm based on Moire interferometry is also used. In addition, algorithms used in this paper are coded by $MMX^{TM}$. A probe system is manufactured to simultaneously inspect 2-D and 3-D for 10mm$\times$10mm field of view, with resolutions of 10 $\mu\textrm{m}$for both x, y axis and 17 $\mu\textrm{m}$for z axis, and then, experiments on several PCBs are conducted. The processing times of 2-D and 3-D, excluding an image capturing, is 0.039 sec and 0.047 sec, respectively. The credible result with $\pm$ 1$\mu\textrm{m}$uncertainty can be also achieved.

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Fiber-Optic Accelerometer by Mach-Zehnder Interferometer (Mach-Zehnder 간섭계를 이용한 광섬유 가속도기)

  • 이기완
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.17 no.10
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    • pp.1092-1099
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    • 1992
  • In this paper, a sensitivity of the gravity acceleration $(0{\sim}1G)$ for a fiber-optic accelerometer is demonstrated. A single mode optical fiber Mach-Zehnder interferometer was used to detect the change in optical path length produced by the strain in the fiber from probe mass about 1 gram. The phase conversion gain of the piezoelectric cylinder in the reference arm with this system measures 0.88rad./v.

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