• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.291-305
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• 2020

Purpose : The duration of speech segments reflects children's speech motor development. The purpose of this study was to determine whether segmental sound and word duration varies by age among preschool children. Methods : A total of 60 children aged 4~5 years participated in this study. Participants took the picture-naming test to produce single-word speech data. The duration of the consonant at the initial position of the word and the final position of the word, the voice onset time of plosive, the duration of the vowel following the initial consonant, and the duration of the word were measured. Results : As age increased, the duration of the initial consonant, the duration of the word, and the voice onset time decreased significantly. The main effects of age, manner of articulation, and place of articulation on the duration of the initial consonant were significant. The duration of consonants in the nasal sound and plosives and the duration of bilabial and alveolar sound differed significantly between groups. The main effects of age and vocal type on voice onset time were significant. The main effect of age on the duration of the consonant in the final position of word and on the duration of the vowel were not statistically significant. Conclusion : The results of this study showed that the duration of segmental sound and the word were associated with speech development between 4 and 5 years old. Accordingly, duration of the segmental sound and the word may serve as an acoustic cue as they reflect speech development and speech motor control maturity.

• Phonetics and Speech Sciences
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• v.16 no.1
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• pp.25-31
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• 2024

This study examines the perceptual motivation behind dissimilation. Consistent with previous arguments suggesting that dissimilation originates from perception rather than production (Coetzee, 2005; Kiparsky, 2003; Scheer, 2013), we hypothesized that an oral stop with short of voice onset time (VOT) would be recognized as non-aspirated more often when it is followed by an aspirated stop with a long VOT. This hypothesis was tested through a perception experiment in which 32 Korean listeners made judgments on the first consonant of C₁VC₂V words manipulated with C₁ VOT and C₂ types. The results revealed that aspirated-based C₁ was recognized as aspirated or tense depending on the duration of VOT, while lenis-based C₁ was consistently recognized as lenis. The dissimilatory effect of aspirated C₂ was confirmed as anticipated, and furthermore, tense C₂ increased the ratio of tense responses more than aspirated C₂. These results provide evidence of a perceptual bias against recurrent aspirated stops, which may play a role in activating a dissimilatory rule or constraint in a language. The assimilatory effect of tense C₂ is in consistent with findings indicating that word-initial tensification is facilitated by the following tense stop in Korean (Kang & Oh, 2016; H. Kim, 2016).

• Asian Spine Journal
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• v.12 no.6
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• pp.1043-1052
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• 2018

Study Design: Level III retrospective cross-sectional study. Purpose: To define and characterize the presentation, symptom duration, and patient/surgical risk factors associated with 'post-decompressive neuropathy (PDN).' Overview of Literature: PDN is characterized by lower extremity radicular pain that is 'different' from pre-surgical radiculopathy or claudication pain. Although it is a common constellation of postoperative symptoms, PDN is incompletely characterized and poorly understood. We hypothesize that PDN is caused by an intraoperative neuropraxic event and may develop early (within 30 days following the procedure) or late (after 30 days following the procedure) within the postoperative period. Methods: Patients who consented to undergo lumbar laminectomy with or without an instrumented fusion for degenerative lumbar spine disease were followed up prospectively from July 2013 to December 2014. Relevant data were extracted from the charts of the eligible patients. Patient demographics and surgical factors were identified. Patients completed postoperative questionnaires 3 weeks, 3 months, 6 months, and 1 year postoperatively. Questions were designed to characterize the postoperative pain that differed from preoperative pain. A diagnosis of PDN was established if the patient exhibited the following characteristics: pain different from preoperative pain, leg pain worse than back pain, a non-dermatomal pain pattern, and nocturnal pain that often disrupted sleep. A Visual Analog Scale was used to monitor the pain, and patients documented the effectiveness of the prescribed pain management modalities. Patients for whom more than one follow-up survey was missed were excluded from analysis. Results: Of the 164 eligible patients, 118 (72.0%) completed at least one follow-up survey at each time interval. Of these eligible patients, 91 (77.1%) described symptoms consistent with PDN. Additionally, 75 patients (82.4%) described early-onset symptoms, whereas 16 reported symptoms consistent with late-onset PDN. Significantly more female patients reported PDN symptoms (87% vs. 69%, p=0.03). Patients with both early and late development of PDN described their leg pain as an intermittent, constant, burning, sharp/stabbing, or dull ache. Early PDN was categorized more commonly as a dull ache than late-onset PDN (60% vs. 31%, p=0.052); however, the difference did not reach statistical significance. Opioids were significantly more effective for patients with early-onset PDN than for those with late-onset PDN (85% vs. 44%, p=0.001). Gabapentin was most commonly prescribed to patients who cited no resolution of symptoms (70% vs. 31%, p=0.003). Time to symptom resolution ranged from within 1 month to 1 year. Patients' symptoms were considered unresolved if symptoms persisted for more than 1 year postoperatively. In total, 81% of the patients with early-onset PDN reported complete symptom resolution 1 year postoperatively compared with 63% of patients with late-onset PDN (p=0.11). Conclusions: PDN is a discrete postoperative pain phenomenon that occurred in 77% of the patients who underwent lumbar laminectomy with or without instrumented fusion. Attention must be paid to the constellation and natural history of symptoms unique to PDN to effectively manage a self-limiting postoperative issue.

• Journal of the Korean Society of Physical Medicine
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• v.11 no.3
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• pp.105-110
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• 2016

PURPOSE: The aim of this study was to investigate the influence of hip abduction velocity and position change on the relative onset times of the gluteus medius, the tensor fascia latae, and the quadratus lumborum in healthy subjects. METHODS: For this study, 15 healthy young adults were recruited. The subjects were asked to move their hip joints up to 35 degrees of abduction at a speed of $70^{\circ}/sec$ and $17.5^{\circ}/sec$ in the supine and side-lying positions. Electromyography data was collected for the gluteus medius, tensor fascia latae, and quadratus lumborum to determine the onset times. RESULTS: There were significant differences between the fast speed ($70^{\circ}/sec$) and the slow speed ($17.5^{\circ}/sec$) in hip abduction in a supine position and in a side-lying position, relatively. The onset time of the gluteus medius was faster than that of the tensor fascia latae and the quadratus lumborum in the side-lying position at the speed of $70^{\circ}/sec$ and $17.5^{\circ}/sec$. CONCLUSION: The findings of this study indicated that hip abduction in a side-lying position is an effective method to recruit the gluteus medius earlier than the tensor fascia latae and the quadratus lumborum. Thus, the exercise position is considered necessory in the purpose of rehabilitation for gluteus medius muscle strengthening program.

• Archives of Craniofacial Surgery
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• v.19 no.3
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• pp.168-174
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• 2018

Background: Safety, efficacy, and time to onset of effect of botulinum toxin type A is of importance to persons who seek improvement in glabellar frown lines, but this has not been well studied. The aim of this study was to determine the safety, efficacy, and onset of action of a newly developed botulinum toxin type A (Nabota) for the treatment of glabellar frown lines. Methods: This was a single-arm, open-label, and phase 4 clinical study. Forty-two subjects with glabellar lines were treated with five times of intramuscular injection of 0.1 mL (4 U/0.1 mL) for a total of 20 U of Nabota. Efficacy and safety were assessed at 2, 3, 4, 5, and 14 days. Efficacy was assessed by the investigator and it was defined as a 1-point change on a 4-point scale. Results: Improvement in glabellar frown lines at maximum frown was observed in 85.4% of subjects 2 days after administration. Improvement in glabellar lines at rest was observed in 51.2% of subjects 2 days after administration, and the proportion of subjects showing improvement increased with time. No severe adverse events were recorded. Conclusion: Onset of action was observed in the majority of subjects by 2 days after administration of Nabota. In addition, Nabota was found to be safe and effective for the treatment of glabellar frown lines.

• Journal of Chest Surgery
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• v.56 no.3
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• pp.186-193
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• 2023

Background: Complete surgical excision is the only curative treatment for primary cardiac tumors. For wide excision, interatrial septal reconstruction (ISR) is commonly performed. We hypothesized that ISR may increase the risk of postoperative atrial tachyarrhythmia (AT) after surgical resection of cardiac myxoma. Methods: After excluding patients with a history of cardiac surgery and concomitant procedures unrelated to tumor resection and those with AT or permanent pacemakers, we finally enrolled 272 adult patients who underwent benign cardiac tumor surgery from 1995 to 2021 at our institution. They were divided into the ISR (n=184) and non-ISR (n=88) groups. The primary outcome was postoperative new-onset AT. Results: The study cohort predominantly consisted of women (66.2%), with a mean age of 57.2±13.6 years. The incidence of postoperative new-onset AT was 15.4%. No 30-day mortality or recurrence was observed. The cardiopulmonary bypass time and aortic cross-clamping time were significantly longer in the ISR group than in the non-ISR group (p<0.001). The median duration of hospital stay of all patients was 6.0 days (interquartile range, 5.0-7.0 days), and no significant difference was observed between the 2 groups (p=0.329). ISR was not an independent predictor of new-onset AT (p=0.248). Male sex and hypertension were found to be independent predictors of new-onset AT. Conclusion: ISR was not a significant predictor of postoperative new-onset AT. ISR might be a feasible and safe procedure for surgical resection of cardiac myxoma and should be considered if needed.

• Journal of Biomedical Engineering Research
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• v.6 no.2
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• pp.53-62
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• 1985

The position and time interval of wave components of the electrocardiogram are used as important data for physician's diagnosis. In case of using the existing definition of the onset of the wave component of the electrocardiogram, they have some problems of defining the precise position of the isoelectric line, of defining the limit of the gradient accepted as the onset, and of the gradient being changed by noise. Therefore, in this paper all time intervals and positions of wave components needed for data of diagnosis were obtained correctly by turning point data reduction algorithm and linear regression intersection algorithm, and the viability of the method of intersecting lines was established in comparison to the four methods of calculating the PR interval.

• Publications of The Korean Astronomical Society
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• v.11 no.1
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• pp.91-107
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• 1996

We determine analytically the onset of thin-shell formation time of fast wind bubble with power-law energy injection $E_{in}=E_0t^s$, and power-law ambient density structure, ${\rho}_0(r)={\bar{\rho}}(r/{\bar{r}})^{-{\omega}}$. Thin-shell formation time, $t_{sf}$ can be estimated by minimizing the total time elapsed before the complete cooling of shocked gas. For uniform medium (${\omega}=0$) and constant energy injection (s = 1), the onset of shell formation is found to be at $t_{sf}=5.2{\times}10^3yr$, which agrees Quite well with the results of FCT 1D numerical calculation. We solve the line transfer problem with previous result derived by numerical calculation in order to calculate line profile of [OIII] (${\lambda}=5007{\AA}$) forbidden line. In general, radiative outer shell causes the formation of double peaked line profile. Each peak corresponds to approaching and receeding shells with large velocities. Our line profiles show good agreements with observation of expanding shell structure.

• Journal of the Korean Applied Science and Technology
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• v.15 no.1
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• pp.47-54
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• 1998

On contraction of the muscles, marked changes in X-ray reflections are observed, suggesting that conformational changes of contractile molecules and the movement of myosin heads during muscle contraction. The time needed to the peak tension after the onset of stimulation and the amount of peak tension depend on the number of twitch cycle. It was found that the successive twitches decreased not only the time needed to the peak tension after the onset of stimulation but also the time needed to the maximum change of the X-ray intensity. However, the difference of the time between the peak tension and the maximum intensity change($T_{i}-I_{i}$) is nearly the same at any twitch. Based on these results the causes of the decrease of $T_{i}$ and $I_{i}$, and physiological implication of $T_{i}-I_{i}$ are discussed.

• Korean Journal of Adult Nursing
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• v.25 no.5
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• pp.483-493
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• 2013

Purpose: The purpose of this study was to examine late-onset hypogonadism, erectile dysfunction, depression, and quality of life among middle-aged male workers. Methods: The subjects included 343 men aged between 40 and 64, responded to self-report questionnaires on general characteristics, late-onset hypogonadism, erectile dysfunction, depression, and quality of life. Data were collected from May 16, 2012 to October 9, 2012 and analyzed using t-test, ANOVA, $x^2$-test, hierarchical multiple regression. Result: The prevalence rate of late-onset hypogonadism was 63.8% with high points in reduction of libido, energy, physical strength and endurance, and erectile function. There were significant differences in late-onset hypogonadism according to age($x^2$=8.98, p=.048) and in erectile dysfunction according to age(F=11.03, p<.001), monthly income(F=2.84, p=.024) and smoking( t=2.96, p=.018). Significant differences were also found in depression according to educational level(F=8.12, p<.001) and in quality of life according to monthly income(F=7.21, p<.001). The factors which influenced quality of life were late-onset hypogonadism, erectile dysfunction, depression, marital status and religion. Conclusion: Symptoms of erectile dysfunction can be improved by smoking cessation education program. In order to improve the life quality of middle-aged men, nursing intervention programs that would both provide proper knowledge on climacteric syndrome and alleviate symptoms should be designed while, at the same time, other programs to evaluate, prevent and control depression are developed.