• The Journal of the Korean life insurance medical association
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• v.27 no.2
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• pp.107-111
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• 2008

The Cervical spondylotic myelopathy (CSM) is degenerative compressive myelopathy which initiation of symptoms seems to be induced by minor cervical trauma or spontaneous event. There was a case of Claim medical examination which was requested to discriminate the cause of ambulatory quadriparesis. Patient asserted that the onset of his myelopathy was followed by minor trauma. The author considered the medical recordings, MRI scan, Claim reports by claim manager. The space available for cord was the smallest at C3-4 level. But on MRI findings, the spinal cord at C3-4 level seemed to be already damaged. There were no recent injury evidences such as hemorrhages, spinal cord contusions, edema, soft tissue hemorrhages. If the space available for cord was small enough to compress the spinal cord, the serious neurologic deficits, non-ambulatory quadriplegia, etc were commonly induced by cervical extension trauma. Patient's asserts did not correspond to his clinical course after cervical trauma. The author reports a case of medical examination for the relationship between symptom onset of cervical spondylotic myelopathy and minor trauma within author's experience.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.18 no.9
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• pp.851-855
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• 2005

We investigated the unbalanced characteristics of the superconducting fault current limiters (SFCLs) based on YBCO thin films with a single line-to-ground fault. When a single line-to-ground fault occurred, the short circuit current of a fault phase increased about 6 times of transport currents after the fault onset but was effectively limited to the designed current level within 2 ms by the resistance development of the SFCL. The fault currents of the sound phases almost did not change because of their direct grounding system. The unbalanced rates of a fault phase were distributed from 6.4 to 1.4. It was found that the unbalanced rates of currents were noticeably improved within one cycle after the fault onset. We calculated the zero phase currents for a single line-to-ground fault using the balanced component analysis. The positive sequence resistance was reduced remarkably right after the fault onset but eventually approached the balanced positive resistance component prior to the system fault. This means that the system reaches almost the three-phase balanced state in about 60 ms after the fault onset at the three-phase system.

• Clinical and Experimental Reproductive Medicine
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• v.46 no.4
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• pp.206-210
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• 2019

Mucopolysaccharidosis type II (MPS II) is a rare X-linked recessive lysosomal storage disease caused by mutation of the iduronate-2-sulfatase gene. The mutation results in iduronate-2-sulfatase deficiency, which causes the progressive accumulation of heparan sulfate and dermatan sulfate in cellular lysosomes. The phenotype, age of onset, and symptoms of MPS II vary; accordingly, the disease can be classified into either the early-onset type or the late-onset type, depending on the age of onset and the severity of the symptoms. In patients with severe MPS II, symptoms typically first appear between 2 and 5 years of age. Patients with severe MPS II usually die in the second decade of life although some patients with less severe disease have survived into their fifth or sixth decade. Here, we report the establishment of a preimplantation genetic diagnosis (PGD) strategy using multiplex nested polymerase chain reaction, direct sequencing, and linkage analysis. Unaffected embryos were selected via the diagnosis of a single blastomere, and a healthy boy was delivered by a female carrier of MPS II. This is the first successful application of PGD in a patient with MPS II in Korea.

• Journal of Korean Public Health Nursing
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• v.31 no.2
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• pp.272-283
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• 2017

Purpose: This descriptive study compared changes in life style and health perceptions before and after the onset of coronary heart disease in 100 patients. Methods: Data were from May to July in 2016 through questionnaires and medical records. The collected data were analyzed by a $x^2$ test, and paired t-test using SPSS 12.0. Results: After the onset of heart disease, significant decreases were observed in smoking ($x^2=17.21$, p<.001) and drinking ($x^2=43.56$, p<.001), while exercise increased significantly ($x^2=32.77$, p<.001). Appetite, stress and health state were significantly decreased after the onset of heart disease (t=3.18, p=.002, t=3.55, p=.001, t=4.43, p<.001), and knowledge about disease was significantly increased after the onset of heart disease (t=-13.66, p<.001). Conclusion: The results of this study indicate that continuous follow-up management programs including smoking and drinking cessation, exercise, appetite and stress management should be developed and implemented for Coronary Heart Disease with PCI.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.11
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• pp.1513-1520
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• 2002

Effect of Convex Surface Curvature on the Onset of Nucleate Boiling of Subcooled Fluid Flow in Vertical Concentric Annuli An experimental study has been carried out to investigate the effect of the transverse convex surface curvature of core tubes on heat transfer in concentric annular tubes. Water is used as the working fluid. Three annuli having a different radius of the inner cores, Ri=3.18mm, 6.35mm, and 12.70mm with a fixed ratio of Ri/Ro=0.5 are used over a range of the Reynolds number between about 40,000 and 80,000. The inner cores are made of smooth stainless steel tubes and heated electrically to provide constant heat fluxes throughout the whole length of each test section. Experimental result shows that heat flux values on the onset of nucleate boiling of the smaller inner diameter model is much higher than that of the larger size test model.

• Journal of Korean Critical Care Nursing
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• v.1 no.1
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• pp.19-31
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• 2008

Purpose: This study was conducted to exam the effects of the Abbreviated Cognitive Behavioral Therapy(ACBT) on chronic insomnia. Methods: Study was one-group interrupted time series study that involved 13 adults(mean age=51.7, aged 25-77 years) with chronic primary insomnia who visited sleep disorder clinic of S Hospital from November 2004 to October 2005. The subjects received 2-session individual ACBT with 2 week-interval($1^{st}$: 1.5- 2hrs, $2^{nd}$: 20-30min). To measure the subjective insomnia severity and sleep patterns, 3 times of insomnia severity index and sleep logs were completed(before ACBT, after ACBT, and 3-month after ACBT). The main outcomes were subjective insomnia severity and sleep patterns(sleep onset latency, waking after sleep onset, and total sleep time, sleep efficiency). The data were analyzed with SPSS 10.0 version program by Friedman test, Wilcoxon signed rank test with Bonferroni correction. Results: There were statistically significant decrease in insomnia severity index, sleep onset latency, and waking after sleep onset, and increase total sleep time and sleep efficiency. Conclusion: ACBT was effective in reducing subjective insomnia severity and improving sleep patterns. Sleep improvement was better sustained over time with ACBT.

• Clinics in Shoulder and Elbow
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• v.7 no.2
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• pp.94-97
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• 2004

Herpes zoster presents clinically with cutaneous vesicular eruption and pain along the dermatome, but it can sometimes cause muscular paralysis. When the disease involves cervical root, it is included in the differential diagnosis of shoulder diseases. A sixty-six year old patient, complaining of severe pain and weakness of his left shoulder, was referred to the authors as having a partial tear of the supraspinatus tendon on MRI. However, the authors found out a paralysis of the sixth cervical root in the patient by electrophysiologic studies, noting that the patient had been affected with a herpes eruption in the neck and arm two months before. Zoster paresis has been reported to be associated with the cutaneous eruption within two weeks of its onset, making its diagnosis not so difficult. The authors report a case of delayed-onset muscular paralysis after cutaneous herpes zoster, which presented just like a rotator cuff tear.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4723-4725
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• 2013

Background: Bladder cancer is a major health problem, especially among men. Opium addiction can be an important risk factor. One important question is whether it can affect the age of onset of bladder cancer. We performed this study to evaluate this question. Materials and Methods: In a cross-section study, records of patients diagnosed with bladder carcinoma in Shahid Labbafinejad Medical Center, within 1999-2008 were included. Data were extracted from records regarding age at onset, gender, smoking status, and opioid addiction and analyzed with SPSS 13. Results: Within 10 years, 920 cases were diagnosed with bladder cancer of which 97 percent were transitional cell carcinoma. In 698 cases, opium addiction status was recorded in 21.3% (n=149). Age at diagnosis was $59.7{\pm}11.51$ (median: 60) among opioid addicts which was significantly lower than nonaddicts ($63.1{\pm}13.65$, Median: 65) (P<0.001). Conclusions: Opium addiction can decrease the age of onset of bladder cancer.

• The Journal of Korean Medicine
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• v.23 no.4
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• pp.73-90
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• 2002

Objectives: This study investigated significant factors that influence functional evaluation of stroke so as to be a fundamental data for estimating prognosis of stroke patients. Methods: 204 patients were studied within 7 days of admission, after the diagnosis of stroke through brain CT scan, brain MRI scan and clinical observations. They were hospitalized in the oriental medical hospital of Dongeui University from February to July in 2001. They were examined at the early stage of onset, after 2 weeks, 4 weeks and 6 weeks, and measured for average mark and the degree of improvement by using the Activity Index. Results: Ischemic stroke, past history of stroke, hypertension, diabetes mellitus, risk factor of obesity, non-professional emergency treatment and hospitalizing time after 1 day from onset, high blood pressure, tachycardia pulse and high blood sugar in abnormal vital sign in acute stage, conscious, cognitive or communication disorder, motor aphasia, dysphagia, constipation for more than 3 days, urinary incontinence, visual field defect, insomnia, and chest discomfort in early stage of onset had a negative influence on functional evaluation. Conclusions: Type of stroke, past history, risk factors, emergency treatment and hospitalizing time after onset, abnormal vital sign and intercurrent symptoms in Acute stage were relevant factors in predicting functional evaluation of stroke.

• Molecules and Cells
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• v.22 no.1
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• pp.30-35
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• 2006

Munc18, a mammalian homolog of C. elegans Unc, is essential for neurotransmitter release. The aim of this study was to identify estrogen-dependent expression of Munc18-1 and its role in the regulation of glutamate release for puberty onset. Hypothalamic munc18-1 mRNA levels were significantly increased by estrogen treatment in ovariectomized, immature female rats. During pubertal development, the munc18-1 mRNA levels dramatically increased between the juvenile period and the anestrous phase of puberty. Intracerebroventricular administration of an antisense oligodeoxynucleotide against munc18-1 mRNA significantly decreased glutamate release and delayed the day of puberty onset. These results suggest that Munc18-1, expressed in an estrogen-dependent manner, plays an important role in the onset of female puberty via the regulation of glutamate release.