• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.16 no.1
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• pp.9-18
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• 2010

For screening test of the non-volatile compounds which migrate from food packaging materials into foodstuffs, the traditional high performance liquid chromatography (HPLC) systems suffer from the lack of universal detector with high sensitivity and universality and high efficiency HPLC separation column which provides complete separation of complex mixtures into all individual substances. In this work, the use possibility of online two-dimensional liquid chromatography (2D-LC) system coupled with a charged aerosol detector (CAD), a universal detector, was reviewed. 2D-LC system permits to improve peak capacity and resolving power for complex mixtures. Charged aerosol detector (CAD) offers a new feasibility for detection of any non-volatile compounds with high sensitivity and constant response factor in a calibration range. The combination of size exclusion chromatography (SEC) and normal phase HPLC (NP-HPLC) is most frequently used for the separation of the natural and synthetic polymers which are mainly used as raw materials for the manufacture of food packaging materials. However, there is no commercial software available for data acquisition and handling and therefore the quantification in 2D-LC analysis is still rare.

• Analytical Science and Technology
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• v.30 no.4
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• pp.167-173
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• 2017

In the era of the forth Industrial Revolution, open source code and open source hardware have gained much attention. In particular, 3D printing technology is expanding into the realms of classical science, technology and our daily lives. Relatedly, in the present study, we demonstrate the manufacture of a nano-LC MALDI spotter robot using 3D printing technology. The parts of the spotter robot were either made using a 3D printer or purchased as 3D printer parts from the 3D printer online market, so that anyone can make the robot without a deep knowledge of engineering or electronics, i.e., DIY (do-it-yourself) product. In the nano-LC MALDI spotter, the nano-LC eluent and MALDI matrix were mixed in a T-union and discharged from the capillary outlet. The eluent and matrix mixture could be spotted onto the movable MALDI plate. The MALDI plate was designed to translate in a two-dimensional space (xy plane), which was enabled by the movements of two stepper motors. In the paper, all computer-aided design (CAD) files for the parts and operation software are provided to help the reader manufacture their own spotter robot.