• Journal of Microbiology and Biotechnology
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• 제17권3호
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• pp.398-402
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• 2007

Abstract Female mice post weaning were exposed to 20 kHz sawtooth electric and magnetic fields (EMF) with $6.25{\mu}T$ peak intensity for 6 weeks. Estrous cycles were checked using vaginal smears over the last 10 days of the experimental period. The vaginal smears from EMF-exposed mice revealed an increase in the frequency of one or two phases persisting. The number of estrous cycles less than 1 was more in the EMF-exposed group than in the sham control group. Furthermore, in the EMF-exposed group, the duration of proestrous and metestrous stages of the estrous cycle was significantly increased compared with the control group. In conclusion, our results suggest that exposure to 20 kHz sawtooth EMF may affect normal cycling of the estrous cycle by disrupting the female reproductive endocrine physiology. We should not disregard the possible adverse reproductive effect of the 20 kHz sawtooth EMF generated under the occupational exposure situation in females.

• Journal of Microbiology
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• 제34권2호
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• pp.158-165
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• 1996

The signal transduction pathways through the RAS gene product and adenyl cyclease play a critical role in regulation of the cell cycle in yeast, Saccharomyces cerevisiae. We examined the genetic relationship between the spt3 gene and ras/cAMP pathway. A mutation in the SPT3 gene suppressed cell cycle arrest at the G1 phase caused by either an inactivation of the RAS or CYR1 gene which encodes a yeast homologue of human ras proto-oncogene or adenyl cyclase, respectively. The phenotypes such as sporulation and heat shock resistancy, that resulted from a partial inactivation of the RAS or CYR1 genes, were also suppressed by the spt3 mutation. Expression of the SSA1 gene encoding one of th heat shock proteins (Hsp70) can be induced by heat shock or nitrogen starvation. Expression of this gene is derepressed in cry1-2 and spt3 mutants. The bcy 1 mutation repressed by the bcy1 mutation, but not in spt3 mutants. These results suggest that the SPT gene is involved in expression of genes that are affected by the RAS/cAMP pathway.

• Nuclear Engineering and Technology
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• 제45권5호
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• pp.653-664
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• 2013

The design of computer-based instrumentation and control (I&C) systems is determined by the allocation of I&C functions to I&C systems and components. Due to the characteristics of computer-based technology, component failures can negatively affect several I&C functions, so that the reliability proof of the I&C systems requires the accomplishment of I&C system design analyses throughout the I&C life-cycle. On one hand, this paper proposes the restructuring of the sequential IEC 61513 I&C life-cycle according to the V-model, so as to adequately integrate the concept of verification and validation. On the other hand, based on a metamodel for the modeling of I&C systems, this paper introduces a method for the modeling and analysis of the effects with respect to the superposition of failure combinations and event sequences on the I&C system design, i.e. the temporal change of physical structure is analyzed. In the first step, the method is concerned with the modeling of the I&C systems. In the second step, the method considers the analysis of temporal change of physical structure, which integrates the concepts of the diversity and defense-in-depth analysis, fault tree analysis, event tree analysis, and failure mode and effects analysis.

• Nutritional Sciences
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• 제9권1호
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• pp.29-34
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• 2006

Purified rat liver aryl sulfotransferase IV (AST IV) was found to be inhibited in vitro by zinc, copper, cadmium and terbium. Among these four elements, zinc, copper and cadmium were all strongly inhibitory to the AST IV activity at very low concentrations (2.5 $\mu$M to 0.025 $\mu$M). In rat liver cytosol, zinc, copper and cadmium at 25 $\mu$M to 0.025 $\mu$M also decreased the AST IV activity to $50\%$ of the controls. In order to assess the possible effects of these metals on the AST IV activity recovery pattern in vivo, studies on the relationship between these minerals and dietary 2-acetylaminofluorene were conducted. Total of forty rats were fed one of five diets for 6 weeks: diet 1, Control diet plus 2-acetlyaminofluorene ($0.05\%$); diet 2, zinc-deficient diet plus 2-acetlyaminofluorene; diet 3, zinc-supplement diet plus 2-acetylaminofluorene; diet 4, copper-supplement diet plus 2-acetylaminofluorene; diet 5, cadmium-supplement diet plus 2-acetylaminofluorene. Half of the rats from each diet were changed to individual diet after 3 weeks of 2-acetylaminofluorene feeding. Placement of rats on the control diet following one cycle of 2-acetylaminofluorene feeding of 3 weeks without 2-acetylaminofluorene resulted in nearly full recovery of AST IV activity within 3 or 4 weeks. However, the rats fed diets that supplemented with zinc, copper or cadmium without 2-acetylaminofluorene showed a new pattern of lowered AST IV activity as early as the first cycle. Also, lowering in cytosolic AST IV contents was appeared in the livers from the rats, following one cycle of 2-acetylaminofluorene feeding of 3 weeks, fed one of the diets that supplemented with copper, cadmium or zinc without 2-acetylaminofluorene for ensuing 3 weeks.

• 한국정보과학회논문지:데이타베이스
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• 제35권3호
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• pp.257-271
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• 2008

무선 방송 환경은 모바일 클라이언트 수에 상관없이 다수의 클라이언트에게 데이타를 보낼 수 있다는 특징이 있다. 이와 같은 특징으로 무선 방송은 많은 분야에 적응되고 있는데 이러한 응용분야에서는 대부분이 읽기 작업을 수행하며 데이타를 일관성 있게 관리하기 위하여 트랜잭션 단위의 동시성 제어기법을 사용하고 있다. 기존 멀티 무선 방송 채널에서의 데이타 할당 방법으로 구성된 데이타 채널들에서는 단일채널에서 사용하는 동시성 제어 기법으로 트랜잭션의 일관성을 보장해 주기 어렵다. 이는 각 데이타 채널의 브로드캐스트 주기가 서로 다르기 때문에 특정 채널에서 데이타를 수신한 후, 다음 채널로 이동하였을 때 트랜잭션이 접근하는 데이타의 일관성이 깨질 수 있기 때문이다. 본 논문에서는 이러한 문제를 해결할 수 있는 멀티 무선 방송채널에서의 읽기 트랜잭션을 위한 동시성 제어 기법을 제안하였다. 이 논문에서는 기본적으로 인덱스 전용 채널과 데이타 전용채널 구조를 이용한다. 또한 LBCPC(Longest Broadcast Cycle Per Channel)라는 새로운 일관성의 단위를 제시한다. 데이타 전용채널에서는 이 LBCPC만큼 같은 BCPC(Broadcast Cycle Per Channel)내의 데이타를 반복하여 방송한다. 또한 LBCPC마다 전체 데이타에 대한 제어 정보를 이용하여 자체적으로 트랜잭션의 검증을 실시한다. 이로 인해 트랜잭션의 일관성이 유지될 뿐만 아니라 단일채널의 긴 브로드캐스트 주기보다 짧은 LBCPC로 인하여 재실행을 위한 대기 시간을 줄여줌으로써 평균 응답 시간을 줄여줄 수 있다. 또한 단일 채널에 비해 제어 정보를 자주 방송함으로써 읽기 전용 트랜잭션이 접근하는 데이타에 대한 최신성을 보장한다. 마지막으로 실험을 통해 단일 채널과의 트랜잭션의 평균 응답 시간이 현저히 감소함을 보임으로써 제안하는 다중 채널에서의 동시성 제어 기법의 성능을 검증한다.

• 한국과학교육학회지
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• 제15권3호
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• pp.284-290
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• 1995

This study examined the effects of the learning cycle model by learner's characteristics such as I.Q., cognitive levels, inquiry skins, cognitive style, activity, reflectiveness. To see the effects of the learning cycle model, nonequivalent control group pretest-posttest multiple treatment designs was used in the study. 99 middle school second-graders(female) were divided into two groups. One group was selected as the experimental group (n=50), the other served at the comparison group(n=49). During the eight-month period, the students in the experimental group were instructed according to the learning cycle model, while the students in the comparison group were instructed according to the traditional instruction methods. Achievement data from science achievement test were analyzed by an ANOVA technique. The results of the study are as follows : 1. Science knowledge achievement. For the lower level students of activity, the learning cycle model is superior to the traditional approaches in science knowledge achievement. 2. Science inquiry skills. For the upper level students of I.Q., cognitive levels, inquiry skills, cognitive style and reflectiveness, the learning cycle model is superior to the traditional approaches in science inquiry skills. 3. Attitudes toward science. For the lower level students of I.Q., cognitive levels, inquiry skills, cognitive style, activity and reflectiveness, the learning cycle model is superior to the traditional approaches in attitudes toward science.

• 한국항만학회지
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• 제14권1호
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• pp.37-45
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• 2000

Centralized safety stock in a periodic replenishment system which consists of one central warehouse and m regional warehouse can reduce backorders allocating the centralized safety stocks to regional warehouse in a certain instant of each replenishment cycle. If the central warehouse can not monitoring inventories in the regional warehouse, then we have to predetermine the instant of allocation according to demand distribution and this instant must be same for all different replenishment cycle. However, transition of inventory level in each cycle need not to be same, and therefore different instant of the allocation may results reduced shortage compare to the predetermined instant of allocation. In this research, we construct a dynamic model based on the assumption of monitoring inventories in the regional warehouse everyday, and develop an algorithm minimize shortage in each replenishment cycle using dynamic programming approach.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 1999년도 추계학술대회논문집
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• pp.83-90
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• 1999

Centralized safety stock in a periodic replenishment system which consists of one central warehouse and m regional warehouse can reduce backorders allocation the centralized safety stocks to regional warehouse in a certain instant of each replenishment cycle. If the central warehouse can not monitoring inventories in the regional warehouse, then we have to predetermine the instant of allocation according to demand distribution and this instant must be same for all different replenishment cycle. However, transition of inventory level in each cycle need not to be same, and therefore different instant of the allocation may results reduced shortage compare to the predetermined instant of allocation. In this research, we construct a dynamic model based on the assumption of monitoring inventories inventories in the regional warehouse everyday, and develop an algorithm minimize shortage in each replenishment cycle using dynamic programming approach.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1996년도 Proceedings of the Korea Automatic Control Conference, 11th (KACC); Pohang, Korea; 24-26 Oct. 1996
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• pp.32-35
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• 1996

Traffic signal cycle optimization is one of the most efficient ways for reducing fuel consumption and improving vehicle waiting time of highsaturated traffic conditions. But most research focused on lowsaturated traffic conditions. Only a few studies have researched traffic control for highsaturated traffic conditions. In this paper reviews the problem of conventional traffic signal system and creates optimal traffic cycle of at the bottom traffic intersection using 27 fuzzy rules. Moreover, to prevent spillback, it can adapt control even though upper traffic intersection has a different saturation rate, road length, road slope and road width.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 추계종합학술대회 논문집
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• pp.779-782
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• 1998

This paper describes a high-speed Dual-modulus Prescaler (DMP) for RF mobile communication systems with pulse remover using selective latch technique. This circuit achieves high speed and low power consumption by reducing full speed flip-flops and using a selective latch. The proposed DMP consists of only one full speed flip-flop, a selective latch, conventional flip-flops, and a control gate. In order to ensure the timing of control signal, duty cycle problem and propagation delay must be considered. The failling edgetriggered flip-flops alleviate the duty cycle problem andthis paper shows that the propagation delay of control signal doesn't matter. The maximum operating frequency of the proposed DMP with 0.6um CMOS technology is up to 2.2㎓ at 3.3V power supply and the circuit consumes 5.24mA.