• 비파괴검사학회지
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• 제30권1호
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• pp.1-5
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• 2010

음향방출법은 압력용기 구조에서 존재하는 결함이나 누출을 탐지하거나 모니터링하는데 유용한 도구로 부상하였다. 본 연구에서는 브레그 격자에 근거한 음향방출센서 시스템이 개발되었다. 다양한 길이의 센싱부를 포함하는 다양한 형태의 광섬유 브레그 격자센서가 제작되었고 PZT 펄서와 연필심 파괴를 이용하여 시험되었다. 두 가지 형태의 센서부착법이 사용되었다. 첫째는 광섬유 브레그 격자센서가 접착제를 이용하여 표면에 완전히 부착되는 방법이고 둘째는 센서의 한쪽 부분만 표면에 부분적으로 고정하고 다른 쪽은 외팔보와 같이 작동하도록 하는 방법이다. 이렇게 함으로써 센싱부의 길이에 비례하는 고유진동수를 갖는 광섬유 브레그 격자센서를 구성할 수 있다. 본 연구에 사용된 센서 시스템의 최종 목적은 원자력발전소 상부 관통관의 균열이나 누출을 탐지하는 온라인 모니터링 시스템에 사용하는 것이다.

• Smart Structures and Systems
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• 제15권3호
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• pp.769-785
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• 2015

Although timber structures have been extensively used in underground temporary supporting system, their actual performance is poorly understood, resulting in potentially conservative and over-engineered design. In this paper, a novel wireless sensor technology, SmartPlank, is introduced to monitor the field performance of timber structures during underground construction. It consists of a wooden beam equipped with a streamlined wireless sensor node, two thin foil strain gauges and two temperature sensors, which enables to measure the strain and temperature at two sides of the beam, and to transmit this information in real-time over an IPv6 (6LowPan) multi-hop wireless mesh network and Internet. Four SmartPlanks were deployed at the London Underground's Tottenham Court Road (TCR) station redevelopment site during the Stair 14 excavation, together with seven relay nodes and a gateway. The monitoring started from August 2013, and will last for one and a half years until the Central Line possession in 2015. This paper reports both the short-term and long-term performances of the monitored timber structures. The grouting effect on the short-term performance of timber structures is highlighted; the grout injection process creates a large downward pressure on the top surface of the SmartPlank. The short and long term earth pressures applied to the monitored structures are estimated from the measured strains, and the estimated values are compared to the design loads.

• 대한원격탐사학회지
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• 제35권1호
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• pp.29-37
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• 2019

Synthetic Aperture Radar (SAR) observations are powerful tools to monitor surface's displacement very accurately, induced by earthquake, volcano, ground subsidence, glacier movement, etc. Especially, radar interferometry (InSAR) which utilizes phase information related to distance from sensor to target, can generate displacement map in line-of-sight direction with accuracy of a few cm or mm. Due to decorrelation effect, however, degradation of coherence in the InSAR application often prohibit from construction of differential interferogram. Offset tracking method is an alternative approach to make a two-dimensional displacement map using intensity information instead of the phase. However, there is limitation in that the offset tracking requires very intensive computation power and time. In this paper, efficiency of parallel computing has been investigated using high performance computer for estimation of glacier velocity. Two TanDEM-X SAR observations which were acquired on September 15, 2013 and September 26, 2013 over the Narsap Sermia in Southwestern Greenland were collected. Atotal of 56 of 2.4 GHz Intel Xeon processors(28 physical processors with hyperthreading) by operating with linux environment were utilized. The Gamma software was used for application of offset tracking by adjustment of the number of processors for the OpenMP parallel computing. The processing times of the offset tracking at the 256 by 256 pixels of window patch size at single and 56 cores are; 26,344 sec and 2,055 sec, respectively. It is impressive that the processing time could be reduced significantly about thirteen times (12.81) at the 56 cores usage. However, the parallel computing using all the processors prevent other background operations or functions. Except the offset tracking processing, optimum number of processors need to be evaluated for computing efficiency.

• 대한예방한의학회지
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• 제23권2호
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• pp.1-10
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• 2019

Backgrounds : In 2017, National Health Insurance implemented the pilot coverage program for Chuna manual therapy(CMT). 65 Korean Medicine(KM) hospitals and clinics were selected in the program to monitor the effectiveness and patients' satisfaction of insured CMT. Objectives : This study aimed to evaluate patients' satisfaction of CMT in the pilot coverage program of National Health Insurance. Methods : Survey participants were recruited among the patients who used CMT at the designated organizations. On-line questionnaire link was sent to the smart phones of patients who agreed to participate in the survey and provide personal contact information. The questionnaire consisted of the basic charactersitics of respondents, imformation on using CMT satisfaction with CMT and willingness to recommend CMT to others. The answers that were automatically coded and saved were statistically analyzed. Results : Of 386 participants who completed the questionnaire, 92.8% satisfied or strongly satisfied with the CMT. Most frequent reason of satisfaction was 'Good effectiveness', and there was no difference in satisfaction between patients of hospital and those of clinics. Patients with the highest and the lowest level of pain satisfied more than those with other pain levels(p=0.003), but the level of copayment and reasons of CMT use did not affect the satisfaction results(p=0.405). The proportions of respondents who had willingness to recommend CMT to others and to revisit for CMT use were 97.8% and 98.8%, respectively. Conclusions : Most patients were satisfied with CMT in the pilot coverage program, and it can provide the rationale for expanding the insurance coverage of CMT to all KM hospitals and clinics.

• Biomolecules & Therapeutics
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• 제27권2호
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• pp.193-200
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• 2019

Ceramide metabolism is known to be an essential etiology for various diseases, such as atopic dermatitis and Gaucher disease. Glucosylceramide synthase (GCS) is a key enzyme for the synthesis of glucosylceramide (GlcCer), which is a main ceramide metabolism pathway in mammalian cells. In this article, we developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to determine GCS activity using synthetic non-natural sphingolipid C8-ceramide as a substrate. The reaction products, C8-GlcCer for GCS, could be separated on a C18 column by reverse-phase high-performance liquid chromatography (HPLC). Quantification was conducted using the multiple reaction monitoring (MRM) mode to monitor the precursor-to-product ion transitions of m/z $588.6{\rightarrow}264.4$ for C8-GlcCer at positive ionization mode. The calibration curve was established over the range of 0.625-160 ng/mL, and the correlation coefficient was larger than 0.999. This method was successfully applied to detect GCS in the human hepatocellular carcinoma cell line (HepG2 cells) and mouse peripheral blood mononuclear cells. We also evaluated the inhibition degree of a known GCS inhibitor 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) on GCS enzymatic activity and proved that this method could be successfully applied to GCS inhibitor screening of preventive and therapeutic drugs for ceramide metabolism diseases, such as atopic dermatitis and Gaucher disease.

• 융합정보논문지
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• 제12권1호
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• pp.172-179
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• 2022

세탁 공정에서 다림질 공정은 세탁 등 다른 공정과는 달리 표준화된 공정처리가 난해하여 수작업에 의존한다. 이는 상의와는 달리 바지는 허리부분에 맵시 주름은 물론 허리 아래에 주름선이 있어서 두 부분으로 분리하여 다려야하기 때문에 2대의 독립된 다림 장비가 개발되어 사용되고 있다. 그러나 이러한 방법은 공정 간의 수동이동으로 작업자의 투입, 공간적 손실, 바지 구겨짐 등의 문제가 발생하여 두 장비를 융합한 바지다림 장치가 요구되고 있다. 본 논문에서 기술하는 일체형 바지다림 시스템은 바지 길이와 모양, 상단부 주름에 무관하게 바지 상단부와 측면부를 자동으로 순차 다림질하며, 또한 다림질 진행 상황을 사용자 모니터에 표시하면서 자가 진단 기능을 수행한다. 본 연구의 결과로 기존의 독립장비 2대를 사용하는 경우보다 다림질 수량을 증가시켜 2배의 성능 향상과 20% 이상의 소비전력을 절감하였다.

• Journal of Microbiology and Biotechnology
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• 제31권12호
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• pp.1615-1623
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• 2021

Picropodophyllotoxin (PPT), an epimer of podophyllotoxin, is derived from the roots of Podophyllum hexandrum and exerts various biological effects, including anti-proliferation activity. However, the effect of PPT on colorectal cancer cells and the associated cellular mechanisms have not been studied. In the present study, we explored the anticancer activity of PPT and its underlying mechanisms in HCT116 cells. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to monitor cell viability. Flow cytometry was used to evaluate cell cycle distribution, the induction of apoptosis, the level of reactive oxygen species (ROS), assess the mitochondrial membrane potential (Δψm), and multi-caspase activity. Western blot assays were performed to detect the expression of cell cycle regulatory proteins, apoptosis-related proteins, and p38 MAPK (mitogen-activated protein kinase). We found that PPT induced apoptosis, cell cycle arrest at the G1 phase, and ROS in the HCT116 cell line. In addition, PPT enhanced the phosphorylation of p38 MAPK, which regulates apoptosis and PPT-induced apoptosis. The phosphorylation of p38 MAPK was inhibited by an antioxidant agent (N-acetyl-L-cysteine, NAC) and a p38 inhibitor (SB203580). PPT induced depolarization of the mitochondrial inner membrane and caspase-dependent apoptosis, which was attenuated by exposure to Z-VAD-FMK. Overall, these data indicate that PPT induced G1 arrest and apoptosis via ROS generation and activation of the p38 MAPK signaling pathway.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 하계종합학술대회논문집
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• pp.54-57
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• 1998

통신망의 물리적 기반이 광케이블로 대치됨에 따라 광케이블 선로의 품질유지 및 체계적인 관리에 대한 요구도 점차 증대되고 있다. 한국통신은 광케이블 선로의 유지보수 체계를 확립하고 자동화 하기 위하여 광선로 운용 감시 시스템(FLOMS:Fiber Line Operation & Monitor System, 이하 FLOMS라 한다.)을 개발하였다. FLOMS는 광케이블 시설에 대한 체계적인 관리 및 광케이블 선로 특성시험 자동호를 통한 선로의 이상 유무를 체크하고 보고할 수 있다. 광케이블 유지보수 요원은 FLOMS 시스템을 이용하여, 운용센터에서 관리대상 전화국의 광케이블 선로들을 원격시험 할 수 있으며 기존의 광전송장치 운용관리 시스템과 연동함으로써 전송분야 운용관리의 통합관리가 가능하게 되었다. 이 시스템을 적용함으로써 광케이블 선로 고장위치의 신속한 파악에 의한 공장시간 단축, 광케이블 선로 특성의 주기적인 측정에 의한 예방보전, 광케이블 심선 정보의 전산화 관리에 의한 업무효율의 향상을 이룩하였다.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제9권2호
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• pp.166-181
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• 2003

최근 인터넷의 급속한 성장으로 Web TV, PDA 및 Web phone과 같은 장치들이 인터넷에 연결되기 시작하고 있다. 그러나, 이러한 장치들은 복잡한 실시간 응용 시스템을 지원하기 위해 RTOS와 같은 실시간 운영체제가 필요로 하게 되었으며, 특히, 내장형 인터넷 응용 시스템을 개발하기 위한 디버거 등과 같은 적절한 도구들의 부족으로 개발하는데 어려움을 겪고 있다. 이에, 본 논문에서는 Qplus-T 실시간 운영 체제 내장형 시스템을 위한 새로운 트레이스포인트 디버깅 도구를 제안하다. 이 도구는 타이밍 트레이스포인트들을 이용하여 실시간 응용 소프트웨어의 디버깅을 쉽게 한다. 전통적인 브레이크포인트 디버거에 비해, 이 트레이스포인트 디버거는 온라인 및 오프라인 분석을 위해 응용 프로그램의 데이터를 동적으로 수집하고 기록하는 기능을 제공한다. 그리고, 응용프로그램의 실행을 멈추거나 원래의 실행 속도에 참견이 거의 없이 실행중인 응용프로그램의 변수들에 새로운 값을 할당해 보기 위한 수단으로도 제공된다. 본 논문에서 제시하는 트레이스포인트 디버거는 Qplus-T 인터넷 응용프로그램과 같은 타겟 실시간 응용 프로그램에 수많은 모니터링 트레이스포인트들을 추가하기 위한 효과적인 방법을 제공하며, 실행 중에 응용프로 그램의 행위를 모니터하고 분석하기 위한 트레이스포인트를 설정할 수 있다. 또한, RTL(Real-Time Logic) 표현을 이용하여 타이밍 문제를 명세화하고 검출할 수 있어 기존 트레이스포인트 디버거와는 다르다.

• 대한영양사협회학술지
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• 제21권3호
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• pp.194-202
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• 2015

The study examined dietary intake, satiety rate, and eating rate using rice bowls with an elevated bottom (diet rice bowl) and rice bowls with an elevated bottom and monitoring line (monitoring rice bowl). The monitoring rice bowl was used to help subjects monitor amounts they had eaten as they ate. Eighteen normal weight college female students participated in this study once a week for 2 weeks. Three hundred grams of fried rice in a diet rice bowl (1st week), and 300 g of fried rice in a monitoring rice bowl were served to the participants over 2 consecutive weeks. After each lunch, dietary intake, satiety rate, and eating rate were measured. The consumption amount of fried rice was 261.6 g in the diet rice bowl group, and 264.8 g in the monitoring rice bowl group. There was no significant difference in fried rice intake between the two groups. The satiety rate of fried rice in the monitoring rice bowl group was significantly higher than that of the diet rice bowl group after 1 hour and 2 hours (P<0.05). The eating rate of the diet rice bowl group (21.3 g/min) was significantly faster than that of the monitoring rice bowl group (18.7 g/min) (P<0.05). This result shows that food consumption monitoring can affect not only eating rate but also the subjective feelings of satiety after meal eating. Although more study is needed, these data suggest consumption monitoring in a rice bowl may help to control obesity and weight.