• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.1
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• pp.1-5
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• 2010

Acoustic emission(AE) has emerged as a powerful nondestructive tool to detect or monitor preexisting defects and leaks in the vessel structures. A Bragg grating based acoustic emission sensor system is developed. Various type of fiber Bragg grating sensor including the variable length of sensing part was fabricated and prototype sensor system was tested by using PZT pulser and pencil lead break sources. Two types of sensor attachment were used. First, the fiber Bragg grating sensor was attached fully to the surface using bonding agent. Second one is that one part of fiber was attached to the surface partly by bonding and the other part of fiber will be act as a cantilever. That is, the resonant frequency of the fiber Bragg grating sensor will depend on the length of sensing part. The final goal of the sensor system is to provide on-line monitoring of cracks or leaks in reactor vessel head penetration of nuclear power plants.

• Smart Structures and Systems
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• v.15 no.3
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• pp.769-785
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• 2015

Although timber structures have been extensively used in underground temporary supporting system, their actual performance is poorly understood, resulting in potentially conservative and over-engineered design. In this paper, a novel wireless sensor technology, SmartPlank, is introduced to monitor the field performance of timber structures during underground construction. It consists of a wooden beam equipped with a streamlined wireless sensor node, two thin foil strain gauges and two temperature sensors, which enables to measure the strain and temperature at two sides of the beam, and to transmit this information in real-time over an IPv6 (6LowPan) multi-hop wireless mesh network and Internet. Four SmartPlanks were deployed at the London Underground's Tottenham Court Road (TCR) station redevelopment site during the Stair 14 excavation, together with seven relay nodes and a gateway. The monitoring started from August 2013, and will last for one and a half years until the Central Line possession in 2015. This paper reports both the short-term and long-term performances of the monitored timber structures. The grouting effect on the short-term performance of timber structures is highlighted; the grout injection process creates a large downward pressure on the top surface of the SmartPlank. The short and long term earth pressures applied to the monitored structures are estimated from the measured strains, and the estimated values are compared to the design loads.

• Korean Journal of Remote Sensing
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• v.35 no.1
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• pp.29-37
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• 2019

Synthetic Aperture Radar (SAR) observations are powerful tools to monitor surface's displacement very accurately, induced by earthquake, volcano, ground subsidence, glacier movement, etc. Especially, radar interferometry (InSAR) which utilizes phase information related to distance from sensor to target, can generate displacement map in line-of-sight direction with accuracy of a few cm or mm. Due to decorrelation effect, however, degradation of coherence in the InSAR application often prohibit from construction of differential interferogram. Offset tracking method is an alternative approach to make a two-dimensional displacement map using intensity information instead of the phase. However, there is limitation in that the offset tracking requires very intensive computation power and time. In this paper, efficiency of parallel computing has been investigated using high performance computer for estimation of glacier velocity. Two TanDEM-X SAR observations which were acquired on September 15, 2013 and September 26, 2013 over the Narsap Sermia in Southwestern Greenland were collected. Atotal of 56 of 2.4 GHz Intel Xeon processors(28 physical processors with hyperthreading) by operating with linux environment were utilized. The Gamma software was used for application of offset tracking by adjustment of the number of processors for the OpenMP parallel computing. The processing times of the offset tracking at the 256 by 256 pixels of window patch size at single and 56 cores are; 26,344 sec and 2,055 sec, respectively. It is impressive that the processing time could be reduced significantly about thirteen times (12.81) at the 56 cores usage. However, the parallel computing using all the processors prevent other background operations or functions. Except the offset tracking processing, optimum number of processors need to be evaluated for computing efficiency.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.2
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• pp.1-10
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• 2019

Backgrounds : In 2017, National Health Insurance implemented the pilot coverage program for Chuna manual therapy(CMT). 65 Korean Medicine(KM) hospitals and clinics were selected in the program to monitor the effectiveness and patients' satisfaction of insured CMT. Objectives : This study aimed to evaluate patients' satisfaction of CMT in the pilot coverage program of National Health Insurance. Methods : Survey participants were recruited among the patients who used CMT at the designated organizations. On-line questionnaire link was sent to the smart phones of patients who agreed to participate in the survey and provide personal contact information. The questionnaire consisted of the basic charactersitics of respondents, imformation on using CMT satisfaction with CMT and willingness to recommend CMT to others. The answers that were automatically coded and saved were statistically analyzed. Results : Of 386 participants who completed the questionnaire, 92.8% satisfied or strongly satisfied with the CMT. Most frequent reason of satisfaction was 'Good effectiveness', and there was no difference in satisfaction between patients of hospital and those of clinics. Patients with the highest and the lowest level of pain satisfied more than those with other pain levels(p=0.003), but the level of copayment and reasons of CMT use did not affect the satisfaction results(p=0.405). The proportions of respondents who had willingness to recommend CMT to others and to revisit for CMT use were 97.8% and 98.8%, respectively. Conclusions : Most patients were satisfied with CMT in the pilot coverage program, and it can provide the rationale for expanding the insurance coverage of CMT to all KM hospitals and clinics.

• Biomolecules & Therapeutics
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• v.27 no.2
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• pp.193-200
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• 2019

Ceramide metabolism is known to be an essential etiology for various diseases, such as atopic dermatitis and Gaucher disease. Glucosylceramide synthase (GCS) is a key enzyme for the synthesis of glucosylceramide (GlcCer), which is a main ceramide metabolism pathway in mammalian cells. In this article, we developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to determine GCS activity using synthetic non-natural sphingolipid C8-ceramide as a substrate. The reaction products, C8-GlcCer for GCS, could be separated on a C18 column by reverse-phase high-performance liquid chromatography (HPLC). Quantification was conducted using the multiple reaction monitoring (MRM) mode to monitor the precursor-to-product ion transitions of m/z $588.6{\rightarrow}264.4$ for C8-GlcCer at positive ionization mode. The calibration curve was established over the range of 0.625-160 ng/mL, and the correlation coefficient was larger than 0.999. This method was successfully applied to detect GCS in the human hepatocellular carcinoma cell line (HepG2 cells) and mouse peripheral blood mononuclear cells. We also evaluated the inhibition degree of a known GCS inhibitor 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) on GCS enzymatic activity and proved that this method could be successfully applied to GCS inhibitor screening of preventive and therapeutic drugs for ceramide metabolism diseases, such as atopic dermatitis and Gaucher disease.

• Journal of Convergence for Information Technology
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• v.12 no.1
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• pp.172-179
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• 2022

Unlike other processes such as washing, the ironing process in the laundry process is difficult to standardize and thus relies on manual labor. Unlike upper garments, pants have pleats at the waist as well as a crease line below the waist, Therefore, two separate ironing devices have been developed and used. However, in this method, problems such as additional worker input, space loss, and wrinkling of pants occur due to manual movement between processes, Consequently, a pants ironing device that combines the two equipments is required. The all-in-one pants ironing system described in this paper automatically sequentially irons the upper part and side of the pants regardless of the length, shape, and upper pleats of the pants. It also performs a self-diagnosis function while displaying the ironing progress on the user's monitor. As a result of this study, it became possible to double the amount of ironing and reduce power consumption by more than 20% compared to the case of using two independent equipment.

• Journal of Microbiology and Biotechnology
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• v.31 no.12
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• pp.1615-1623
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• 2021

Picropodophyllotoxin (PPT), an epimer of podophyllotoxin, is derived from the roots of Podophyllum hexandrum and exerts various biological effects, including anti-proliferation activity. However, the effect of PPT on colorectal cancer cells and the associated cellular mechanisms have not been studied. In the present study, we explored the anticancer activity of PPT and its underlying mechanisms in HCT116 cells. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to monitor cell viability. Flow cytometry was used to evaluate cell cycle distribution, the induction of apoptosis, the level of reactive oxygen species (ROS), assess the mitochondrial membrane potential (Δψm), and multi-caspase activity. Western blot assays were performed to detect the expression of cell cycle regulatory proteins, apoptosis-related proteins, and p38 MAPK (mitogen-activated protein kinase). We found that PPT induced apoptosis, cell cycle arrest at the G1 phase, and ROS in the HCT116 cell line. In addition, PPT enhanced the phosphorylation of p38 MAPK, which regulates apoptosis and PPT-induced apoptosis. The phosphorylation of p38 MAPK was inhibited by an antioxidant agent (N-acetyl-L-cysteine, NAC) and a p38 inhibitor (SB203580). PPT induced depolarization of the mitochondrial inner membrane and caspase-dependent apoptosis, which was attenuated by exposure to Z-VAD-FMK. Overall, these data indicate that PPT induced G1 arrest and apoptosis via ROS generation and activation of the p38 MAPK signaling pathway.

• Proceedings of the IEEK Conference
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• 1998.06a
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• pp.54-57
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• 1998

As the physical layer on telecommunication network is replaced fiber optic lines, it is increased the need of systematic maintenance for fiber optic lines. Korea Telecom has developed FLOMS in order to establish maintenance processes for optical fiber lines. FLOMS has functions which manages optical facilities and tests optical fiber lines automatically. As a resuls, this system can check and/or report a fault. Operator, who is reponsible for management of optical fiber lines, can test the characteristics of optical fiber lines remotely using FLOMS. As interpoerable with Digital Transmission Management System, FLOMS provides efficient management for optical fiber lines. This system improves the work process to find fault location fast, detect the degradation of fiber quality, and make database of optical facilities efficiently.

• Journal of KIISE:Computing Practices and Letters
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• v.9 no.2
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• pp.166-181
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• 2003

With the rapid growth of Internet, many devices such as Web TVs, PDAs and Web phones, begin to be directly connected to the Internet. These devices need real-time operating systems (RTOS) to support complex real-time applications running on them. Development of such real-time applications called embedded internet applications, is difficult due to the lack of adequate tools, especially debuggers. In this paper we present a new tracepoint debugging tool for the Qplus-T RTOS embedded system, which facilitates the instrumentations of the real-time software applications with timing trace-points. Compared with traditional breakpoint debugger, this trace-point debugger provides the ability to dynamically collect and record application data for on-line examination and for further off-line analysis. And, the trace-points can also provide the means for assigning new values to the running application's variables, without neither halting its execution nor interfering with its natural execution flow. Our trace-point debugger provides a highly efficient method for adding numerous monitoring trace-points within a real time target application such as Qplus-T internet applications, utilizing these trace-points to monitor and to analyze the application's behavior while it is running. And also, our trace debugger is different from previous one in that we can specify and detect the timing violations using its RTL (Real-Time Logic) trace experiments.

• Journal of the Korean Dietetic Association
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• v.21 no.3
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• pp.194-202
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• 2015

The study examined dietary intake, satiety rate, and eating rate using rice bowls with an elevated bottom (diet rice bowl) and rice bowls with an elevated bottom and monitoring line (monitoring rice bowl). The monitoring rice bowl was used to help subjects monitor amounts they had eaten as they ate. Eighteen normal weight college female students participated in this study once a week for 2 weeks. Three hundred grams of fried rice in a diet rice bowl (1st week), and 300 g of fried rice in a monitoring rice bowl were served to the participants over 2 consecutive weeks. After each lunch, dietary intake, satiety rate, and eating rate were measured. The consumption amount of fried rice was 261.6 g in the diet rice bowl group, and 264.8 g in the monitoring rice bowl group. There was no significant difference in fried rice intake between the two groups. The satiety rate of fried rice in the monitoring rice bowl group was significantly higher than that of the diet rice bowl group after 1 hour and 2 hours (P<0.05). The eating rate of the diet rice bowl group (21.3 g/min) was significantly faster than that of the monitoring rice bowl group (18.7 g/min) (P<0.05). This result shows that food consumption monitoring can affect not only eating rate but also the subjective feelings of satiety after meal eating. Although more study is needed, these data suggest consumption monitoring in a rice bowl may help to control obesity and weight.