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Inhibitory Effects of Apple Peel Extract on Inflammatory Enzymes (사과 과피 추출물의 염증 관련 효소 억제 효과)

  • Kim, Ilrang
    • Korean Journal of Food Science and Technology
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    • v.47 no.4
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    • pp.534-538
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    • 2015
  • The purpose of this study was to investigate the biological benefits of apple peel. The antioxidant and anti-inflammatory activities of a 70% ethanol extract of apple peel were examined. The total phenolic compound and flavonoid contents of apple peel were $6.8{\pm}0.5mg$ gallic acid equivalent/g of fresh weight and $3.3{\pm}0.3mg$ catechin equivalent/g of fresh weight, respectively. Antioxidant activity was evaluated by measuring 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. The DPPH radical scavenging activity of apple peel was $18.9{\pm}1.6$, $46.3{\pm}2.3$ and $58.1{\pm}3.9%$ at concentrations of 0.1, 0.5 and 1.0 mg/mL, respectively (p<0.05). The anti-inflammatory effect was investigated by measuring the inhibition of inflammatory enzymes. Apple peel significantly inhibited secretory phospholipase, cyclooxygenase-1, cyclooxygenase-2, and lipoxygenase activity by up to $53.5{\pm}2.3$, $13.4{\pm}1.8$, $64.8{\pm}5.4$ and $44.4{\pm}4.5%$, respectively (p<0.05). Taken together, these findings suggest that apple peel may act as an antioxidant by radical scavenging and may possess potential anti-inflammatory properties for suppressing the activity of inflammatory enzymes. These results also suggest that apple peel can be utilized as a health functional food ingredient possessing antioxidant and anti-inflammatory activities.

Mineral Leaching from Air-Dried Forages (마른 목초(牧草) 잎으로 부터의 무기물(無機物) 용출(溶出))

  • Kim, S.D.;YOSHIDA, Shigekata
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.3
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    • pp.265-272
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    • 1999
  • In this study in order to know the behavior of mineral nutrients from forage plant to soil in a grassland ecosystem, the leaching of minerals (K, Mg, Ca, N and P) from air-dried (dead) plant body was investigated by putting orchardgrass (Dactylis glomerata L.) hay on meadow during a month with seasonal changes. The results obtained were as follows; 1) The K content of the forage, not stable during the experimental seasons, tended to decrease in the summer of 1986, while the Mg and Ca contents increased in the summer. The reason might be a different response (solubility or leaching liability) of the monovalent mineral (K) and divalent ones (Mg and Ca) in the forage to rainfall. 2) The percentage of P to the initial amount in the forage showed larger decrease in a rainy period (Feb.~Mar., 1986) and during the rainy summer (May to July). The P component of the forage might be easily leached with water. 3) The percentage of the four minerals (Ca, N, Mg, K) remained the least in the period of (Jun.~Jul., 1986), 4) Though the percentage of remained Mg and N of the forage varied very similarly, the percentage of remained N was higher than that of Mg during periods before summer (January to May), while after the period the ratio of the Mg seemed to be higher than that of the N (June to December), 5) During the periods until (May~Jun., 1986) the percentage of remained K and P of the forage varied in very similar pattern, and the order of remained mineral was as follows; $Ca>N{\geq}Mg>P=K$. But from the period of (Jun-Jul) the ratio of P remained in the forage increased nearly up to the ratio of N, and the order was as follows; $Ca>Mg{\geq}N{\geq}P>K$.

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Effect of Planting Date and Hybrid on Forage Yield and Quality of Corn for Silage. II. Fiber component and digestibility of ear, stover and whole plant (파종시기 및 품종이 사일리지용 옥수수의 수량과 사료가치에 미치는 영향 II. 경엽, 암이삭 및 전식물체의 섬유소 및 소화율)

  • Kim, J.D.;Kim, D.A.;Lee, J.K.;Kim, J.G.;Kang, W.S.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.3
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    • pp.221-232
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    • 1999
  • Dry matter yield and ear percent are commonly considered the most important factors for evaluating silage corn(Zea mays L.) hybrids for silage production. But quality of stover as well as forage production in important in identification of hybrids. The objective of this study was to evaluate nutritional value of stover, ear and whole plant from eight corn hybrids for silage at two dates of planting. In content of fiber components(ADF, NDF, ADL, hemicellulose and cellulose) from stover, ear and whole plant samples, optimum planting corn was lower than late planting one(P<0.01). Differences(P<0.01) in the content of fiber components in stover and whole plant were observed among the corn hybrids. Differences between different planting dates in TDN and $NE_1$ were detected in the stover and whole plant samples(P<0.05). Differences among the corn hybrids in TDN and $NE_1$ were also observed in stover, ear and whole plant samples. TDN and $NE_1$ of 'G4624', 'P3352' and 'P3394' for whole plant were higher than those of the other corn hybrids. ln vitro dry matter digestibility(IVDMD) at optimum planting date was higher than that of late(P<0.05), and there also were significant differences among the corn hybrids. Correlation coefficients for whole plant IVDMD with NDF, ADF, hemicellulose, and cellulose were $-0.82^{**}$, $-0.71^{**}$, $-0.63^{**}$, and $-0.69^{**}$, respectively. Results of this study indicate that optimum planting of corn resulted in increased quality of silage corn. Differences among corn hybrid, particularly, in nutritive value of stover and whole plant were also observed. Therefore, the nutritional value of stover and whole plant may be important in assessing the corn hybrids for silage.

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Effect of Planting Date and Hybrid on Forage Yield and Quality of Corn for Silage I. Agronomic characteristics and forage yield of corn (파종시기 및 품종이 사일리지용 옥수수의 수량과 사료가치에 미치는 영향. I. 옥수수의 생육특성 및 사초수량)

  • Kim, J.D.;Kim, D.A.;Park, H.S.;Kim, S.G.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.3
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    • pp.211-220
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    • 1999
  • The corn is mostly planted in mid-April in single-cropping silage system if possible, however, in a double-cropping silage system, the corn planting date is delayed until after the mid-May. The objective of this study was to evaluate agronomic characteristics and forage performance of the eight government recommended corn hybrids for silage at two dates of planting. Split-plot design replicated three times was used, that is, main plots were planting dates, sub-plots were eight hybrids at Suweon in 1997. Days from planting to silking of optimum planting was 84 days and that of late was 69 days. The difference in silking day among the hybrids was 6 days at optimum planting and 2 days at late planting. Plant height of optimum planting corn was higher than that of late one, however, ear height and stem diameter of optimum planting were lower than those of late planting corn. Among the corn hybrids tested, plant heights of 'P3156' and 'P3163' were higher than those of the other hybrids. Ear height of 'DK713' was the lowest among the corn hybrids and stem diameter of 'P3394' was thicker than that of the other hybrids. European corn borer(ECB) damage(16.6%) at optimum planting was lower than that(49.9%) of late, however, there were no significant ECB damage differences among the corn hybrids tested. Whole plant dry matter(DM) contents of 'P3525', 'P3394' and 'P3352' hybrids were higher than those of the other corn hybrids at harvest. Ear percentages of the total dry matter(DM) of 'P3394' and 'P3156' were higher than those of the other corn hybrids. Dry matter(DM) and total digestible nutrients(TDN) yields(19,696 and 14,621kg/ha) at optimum planting were higher than those (17,163 and 12,570kg/ha) of late planting, while there were no significant differences in DM and TDN yields among the corn hybrids tested. And those hybrids with greater proportion of grain in the whole plant have higher DM and TDN yields. Correlation coefficients for days from planting to silking with DM and TDN yields were $0.84^{**}$ and $0.87^{**}$, and those for ear percent were $0.86^{**}$ and $0.87^{**}$. Results of this study indicate that optimum planting date(15 April) is better than late planting date(16 May) in agronomic characteristics and forage production of silage corn. Days from planting to silking and ear percent as welI as other characters are important factors screening the corn hybrid for silage.

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Studies on Utilization Survey and Forage Quality of Phragmites communis and Miscanthus sinensis as Native Grasses in Paju and Ansan District, 2010 (2010 파주, 안산지역 갈대, 억새 등 야초류의 이용실태와 사료가치 평가)

  • Seo, Sung;Kim, Won-Ho;Jung, Min-Woong;Park, Hyung-Soo;Shim, Jae-Jin;Park, Jin-Gil;Sung, Ha-Guyn;Kim, Jong-Duk;Lee, Joung-Kyong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.31 no.2
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    • pp.151-158
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    • 2011
  • This study was carried out in 2010 to investigate the utilization and nutritive value of native grasses, such as Phragmites communis and Miscanthus sinensis which might reduce the cost of feeding domestic cattle. The regions within the Civilian Control Line in Paju and Sihwa region in Ansan were surveyed. In Paju, the yearly silage production was 900 MT harvested from 90 ha (10 MT/ha). About 30~50% of these were sold out at the marketing price of 52,000~55,000 Won per roll (130~137.5 Won/kg). Regrown Miscanthus sinensis of 70 cm in length contained 9.6% of crude protein (CP), 82.4 of relative feed value (RFV), and 67.7% of in vitro dry matter digestibility (IVDMD). Regrown Phragmites communis of 70 cm in length contained 13.8% of CP, 84.3 of RFV, and 67.9% of IVDMD. As harvesting was delayed, the quality was decreased dramatically. In Ansan region, Phragmites communis plantation covers 100 ha. The silage production was 550 MT from the area of 50 ha (11 MT/ha) in 2009. And the marketing price was 50,000 Won per roll. But in 2010 only a small amount of grasses could have been baled due to frequent and much rainfall from spring to summer season. However, the good forage quality was observed from regrown Phragmites communis of 80 cm in length, 12.9% CP, 99.8 RFV and 66.6% IVDMD, while that of late matured grasses was very low, 2.2% CP, 52.9 RFV and 36.4% IVDMD, greatly lower than forage quality of rice straw. The quality of grasses at bloom stage of 150 cm in length was similar to that of rice straw, showing 4.5% CP, 59.9 RFV and 42.2% IVDMD. In conclusion, the overall quality of most native grasses in this survey were very poor. Therefore, we recommend that Phragmites communis and Miscanthus sinensis should be harvested during June or July to obtain better forage quality which is richer in forage values than rice straw. Production of high quality forage crops was also desirable for self sufficiency of forage.

Selection of Representative Foods and 'Best-fit' Mapping of Other Foods for Estimation of a Comprehensive Exposure to Food Contaminants in a Korean Total Diet Study (한국인의 유해물질 식이 노출량 평가를 위한 대표식품 선정과 mapping)

  • Koh, Eun-Mi;Shin, Hye-Hyung;Yon, Mi-Yong;Nam, Eun-Jeong;Lee, Yoon-Na;Kim, Do-Hee;Lee, Jee-Yeon;Kim, Mee-Hye;Park, Sung-Kug;Choi, Hoon;Kim, Cho-Il
    • Korean Journal of Food Science and Technology
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    • v.43 no.6
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    • pp.773-782
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    • 2011
  • A food list representing the typical diet of Koreans was developed for a total diet study based on the 687 food items which appeared in the dietary intake data collected during the 2008 & 2009 Korea National Health & Nutrition Examination Survey. Food items included in 90% of the cumulative intake, items with a consumption frequency of 5% or higher and items contributing to 80% of cumulative fat intake were considered first. From the resulting 165 food items, 15 items were removed to avoid similar foods, while 10 distinct items were added to increase the efficiency of 'best-fit' mapping. Consequently, 160 items were selected as representative foods, which cover 90.93% of intake amount, 91.36% of energy intake and 89.05% of fat intake. Given that every food consumed by Koreans can't be analyzed for contaminants of interest, mapping other foods to the previously mentioned representative 160 foods is warranted because it enables a more comprehensive dietary exposure assessment that is close to reality.

Assessment of Estimated Daily Intakes of Propyl Gallate, EDTA (ethylenediamine tetra acetate), and Erythorbic Acid in Korea (식품을 통한 몰식자산프로필, 이디티에이, 에리쏘르빈산의 섭취량 평가)

  • Suh, Hee-Jae;Choi, Sung-Hee
    • Korean Journal of Food Science and Technology
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    • v.43 no.6
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    • pp.766-772
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    • 2011
  • This study was conducted to evaluate the daily intakes of propyl gallate, EDTA (ethylenediamine tetra acetate), and erythorbic acid for average consumers by age group and the intake of high consumers ($95^{th}$ percentile) in Korea. The average intake of EDTA was $1.14{\mu}g/kg{\cdot}bw/day$, and 0.0% of the ADI (acceptable daily intake) established by JECFA (Joint FAO/WHO Expert Committee on Food Additives). The $95^{th}$ percentile intake of EDTA was $141.24{\mu}g/kg{\cdot}bw/day$ (5.6% of ADI). The average intake of erythorbic acid was $16.93{\mu}g/kg{\cdot}bw/day$, and the 3-6 year-old group had the highest consumption ($58.43{\mu}g/kg{\cdot}bw/day$), which was <1.0% of the ADI established by the EU (European Union). The $95^{th}$ percentile intake of erythorbic acid was $1,320.31{\mu}g/kg{\cdot}bw/day$ and 22.0% of the ADI. In conclusion, daily intakes of propyl gallate, EDTA, and erythorbic acid in Korea were at safe levels in all age groups and also in high consumers.

Antiemetic Effect of Dolasetron Mesylate in the Prevention of Acute and Delayed Nausea and Vomiting due to Moderately Emetogenic Chemotherapy (악성종양환자에서 중등도 이상의 오심, 구토를 유발하는 항암화학요법 시급성 및 지연성 오심, 구토의 예방에 대한 Dolasetron의 효과)

  • Kim, D.S.;Sung, H.Y.;Choi, K.M.;Paik, J.Y.;Roh, S.Y.;Moon, H.;Kim, C.C.;Hong, Y.S.
    • Journal of Hospice and Palliative Care
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    • v.7 no.2
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    • pp.248-257
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    • 2004
  • Purpose: To evaluate the efficacy of dolasetron mesylate in controlling nausea and vomiting in the first 24 hours and to extend these comparisons over the next 4 days in patients receiving moderately emetogenic chemotherapy. Methods: This was a single center, open-labeled study with single arm. Dolasetron (1.8 mg/kg) was given intravenously (I.V.) prechemotherapy with 10 mg of dexamethasone IV, followed 24 hours later by oral dolasetron (200 mg once daily) for the subsequent 4 days. The frequency of vomiting, severity of nausea and the presence of rescue antiemetics were assessed daily. Results: Of 30 patients enrolled, 28 were eligible and evaluable for the efficacy. Four out of 28 patients had complete control of nausea and vomiting without any rescue antiemetics through 5 days. The complete control got better as time went by with the rates of 17.9/46.4/42.9/53.6/60.7% on days 1 to 5. Vomiting was better controlled than nausea in both cisplatin-containing and non-containing chemotherapy. The adverse events were mild to moderate degrees of headache, diarrhea and fever, but were recovered spontaneously. Conclusion: Dolasetron was effective and safe for the control of nausea and vomiting in the patients with moderately emetogenic chemotherapeutic agents.

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Survey on Quality of Hospice.Palliative Care Programs in Korea (한국 호스피스.완화의료기관 실태 조사)

  • Yun, Young-Ho;Choi, Eun-Sook;Lee, In-Jeong;Rhee, Young-Sun;Lee, Jung-Suk;You, Chang-Hoon;Kim, Hyun-Sook;Paek, Yu-Jin
    • Journal of Hospice and Palliative Care
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    • v.5 no.1
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    • pp.31-42
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    • 2002
  • Purpose : The purpose of this study was to evaluate the present status of hospice palliative care programs in Korea as a basic database for standardization of hospice palliative care. Method : The data was collected from July to October, 2001. The instrument used for this study was the questionnaires which was consisted of the general characteristics of organization, recipient of service, manpower, contents of service, financial conditions and facilities. Sixty-four hospice palliative care programs answered the questionnaires, confirmed by telephone. Results : They were 40 hospital-based hospice palliative care programs and 24 nonmedical hospice palliative care programs. 11 Hospital-based hospice palliative programs have isolated unit or hospital affiliated free standing hospice. 6 Non-hospital hospice palliative programs have a free standing hospice. Major subjects of hospice palliative program were terminal cancer patients but patients with non-terminal illness were also included. Only 24 of 64 hospice palliative programs had all of the essential professionals : physicians, nurses, social workers, and clergies. Home hospice palliative care programs have a referral system in hospital based (89.7%) and nonmedical programs (73.7%). 24hr hospice are were provided in 26 hospital-based (65.0%) and 9nonmedical programs (37.5%). There were rooms for family in half of hospital-based programs. 73.9% of hospice palliative care programs have financial problems. 62.0% of Hospice palliative care programs need financial support from government. Conclusion : 64 Hospice palliative care programs provided hospice palliative services but had many problems in manpower, quality of care and facility. For improving the quality of terminal patients' life and promoting the cost effectiveness of health care resources, it is necessary to consider the standardization and institutionalization of hospice palliative care.

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Spiritual Welling-Being, Attitude to Death and Perception of Hospice Care in College Students (대학생의 영적안녕과 죽음에 대한 태도 및 호스피스 인식)

  • Lee, Young Eun;Choi, Eun Ah;Lee, Kyoung Eun
    • Journal of Hospice and Palliative Care
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    • v.18 no.4
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    • pp.294-305
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    • 2015
  • Purpose: The purpose of this study is to provide baseline data for the development of an educational program for hospice care for college students. Methods: A survey was conducted at three universities in B city with 143 students from September 5, 2014 through September 26, 2014. The data were analyzed by the SPSS 18 program. This study was approved by IRB. Results: The college students' spiritual well-being was at a medium level. Their attitudes to death were neutral, and perception of hospice care was at a medium level. Most of the participants (93.0%) had no training in hospice care. The participants' awareness of the purpose of hospice care was at a relatively high level. Their awareness of the need for hospice care was at a moderate level. The participants' spiritual well-being and their attitudes to death showed a weak but positive correlation (r=0.179, P=0.030). The relationship between their spiritual well-being and awareness of hospice care were positively correlated (r=0.203, P=0.015). Conclusion: The participants' perception of hospice care was low. Most of them had no experience of hospice care education. Also, the higher the spiritual stability was, the higher the participants' perception of the purpose and the necessity of hospice care was. And their perception of the hospice care varied depending on their family relationship, satisfaction with school life, and cognition of hospice care. Therefore, we need consider these variables to develop a hospice education program to enhance college students' attitudes to death and their perception of hospice care.