• Speech Sciences
• /
• v.7 no.1
• /
• pp.65-75
• /
• 2000

The present study attempted to determine the effect of olfactory stimulation on word retrieval deficit in Korean aphasics. Eleven nonfluent and 9 fluent aphasic patients served as subjects. The 20 subjects' age ranged from 14 to 65 with the mean of 43.0 (SD: 17.6). A neurologist examined them and diagnosed that they had no visual, auditory, and olfactory impairment. The study consisted of 2 experiments: Experiment I included visual stimulation while experiment II included visual and olfactory stimulation. The subjects were presented with 19 pictures for them to name in the experiment I, whereas they were exposed to the 19 pictures along with the corresponding olfactory stimulus in the experiment II. The 19 items included soy sauce, chilly pepper, Kimchi, chewing gum, cigarette (smoked), soybean paste, lemon, banana, alcohol (wine), apple, fish, vinegar, cuttlefish (dried), milk, rose, sesame oil, melon, coffee, and perfume. The results were as follows: First, olfactory stimulation tended to improve aphasics' word retrieval deficit although the improvement was not statistically significant. Second, the nonfluent aphasics seemed to take more advantage from olfactory stimulation compared to the fluent aphasics. Third, olfactory stimulation (olfactory + visual) did not produce a different naming performance compared to visual stimulation in the pre- and post-test when the pre- and post-test was composed of naming tasks through auditory + visual stimulation. Fourth, the fluent aphasics performed better with unpleasant olfactory stimulus while the nonfluent aphasics performed better with pleasant olfactory stimulus.

• Journal of Korean Physical Therapy Science
• /
• v.26 no.2
• /
• pp.24-31
• /
• 2019

Purpose: The purpose of this study was to investigate the effect of olfactory stimulation on the balance ability of the elderly. Design: Randomized controlled trial. Methods: A total of 20 subjects were randomly assigned to the olfactory stimulation group (2 males and 8 females) and deception olfactory stimulation group (3 males and 7 females). Subjects were subjected to 30 second 3 times olfactory stimulation and deception olfactory stimulation, and the assessment measured pre and post postural distance and postural speed. Results: In the elderly, the olfactory stimulation group was significantly improved the postural distance and postural speed in the eyes closed state than the deception stimulation group (p<.05). Conclusion: As the information is provided through the olfactory stimulation, the postural distance and postural speed are significantly improved. therefore, it is expected that the olfactory stimulation in the elderly will be an effective intervention method to prevent fall.

• Journal of Korea Entertainment Industry Association
• /
• v.14 no.3
• /
• pp.403-410
• /
• 2020

The purpose of this study was to determine whether olfactory stimulation would improve spasticity, balance ability and quality of life in stroke patients. Twenty-one stroke patients were recruited and were randomly divided into two groups: olfactory stimulation group (n=10) and sham stimulation group (n=11). Participants in both groups received conventional physical therapy for 30 minutes before the intervention. Additionally, subject in the olfactory stimulation group performed olfactory stimulation using lavender oil for 6 minutes (2 minx3 set), five times a week for two weeks, while the sham stimulation group conducted olfactory stimulation using water for the same amount of time. Composite-Spasticity-Score was used to assess spasticity level of ankle plantar-flexors. Dynamic balance was measured using a TUG. Postural-sway distance was measured using a force platform. Quality of life were measured by SF-36. There was no significant difference within group and between the groups in the spasticity. Significant improvement in postural-sway and TUG were observed in the olfactory stimulation group compared to the sham stimulation group (p<0.05). The Mental Componnt Summary of the SF 36 in the olfactory stimulation group improved significantly greater than the sham stimulation group (p<0.05). Our findings indicate that olfactory stimulation is beneficial and effective to improve balance ability and quality of life in stroke patients.

• Molecules and Cells
• /
• v.38 no.6
• /
• pp.535-539
• /
• 2015

Olfactory stimulation activates multiple signaling cascades in order to mediate activity-driven changes in gene expression that promote neuronal survival. To date, the mechanisms involved in activity-dependent olfactory neuronal survival have yet to be fully elucidated. In the current study, we observed that olfactory sensory stimulation, which caused neuronal activation, promoted activation of the phosphatidylinositol 3'-kinase (PI3K)/Akt pathway and the expression of Bcl-2, which were responsible for olfactory receptor neuron (ORN) survival. We demonstrated that Bcl-2 expression increased after odorant stimulation both in vivo and in vitro. We also showed that odorant stimulation activated Akt, and that Akt activation was completely blocked by incubation with both a PI3K inhibitor (LY294002) and Akt1 small interfering RNA. Moreover, blocking the PI3K/Akt pathway diminished the odorantinduced Bcl-2 expression, as well as the effects on odorant-induced ORN survival. A temporal difference was noted between the activation of Akt1 and the expression of Bcl-2 following odorant stimulation. Blocking the PI3K/Akt pathway did not affect ORN survival in the time range prior to the increase in Bcl-2 expression, implying that these two events, activation of the PI3K pathway and Bcl-2 induction, were tightly connected to promote post-translational ORN survival. Collectively, our results indicated that olfactory activity activated PI3K/Akt, induced Bcl-2, and promoted long term ORN survival as a result.

• Journal of Oral Medicine and Pain
• /
• v.42 no.3
• /
• pp.62-71
• /
• 2017

Purpose: The purpose of this study was to examine the rate of salivation before and after olfactory stimulation using BPO (black pepper oil) and then, to collect basic data for screening the possibility of introducing olfactory stimulus to prevent and improve dry mouth. Methods: The subjects in this study were 60 college students in Jeon-Nam province. The subjects were randomly divided into 3 groups; the BPO group (n=20), the lavender oil (LVO) group (n=20), and the distilled water (DW) group (n=20). The amount of whole saliva before and after olfactory stimulation was measured 14 times for a 4-week period. Results: In the BPO and LVO groups, the amount of whole saliva increased after the olfactory stimulation and it was most prominent in the BPO group (p<0.05). The difference of whole salivation was higher in the BPO group (p<0.05) and there was no significant difference in the salivary flow rate in the DW group. After 14 times of measurement for 4 weeks, the BPO and LVO groups showed an increase in salivary rate at an early stage compared without stimulation (p<0.05), but there was no significant difference between the 2 groups in the middle. Since the twelfth measurement, whole saliva secretion increased and maintained the elevated level (p<0.05). Conclusions: The olfactory stimulation using BPO may contribute to stimulating salivation. Further studies are needed for subjects with dry mouth symptoms. In the future, qualitative and quantitative studies should be conducted for people who complains about oral dryness.

• Korean Journal of Clinical Laboratory Science
• /
• v.51 no.4
• /
• pp.462-467
• /
• 2019

Many studies in recent decades have revealed that olfactory stimulation by perfume or malodor inhalation exerts various psychological and physiological effects on humans. The most recent studies have examined the electrophysiological response of olfactory stimulation on the activity of human cortical nerve cells. The purpose of this current study is to quantitatively analyze what changes occur in the alpha activity in healthy participants (N=12) on olfactory stimulation using two types of odors (acacia and butanol). Exposure to the odor of acacia perfume was associated with a significant increase (66.7%) in alpha activity when compared with that of the no-odor background EEG. Exposure to the odor of butanol was associated with a significant reduction (33.3% to 41.7%) in EEG alpha activity when compared with that of the no-odor control. The results of this study demonstrated the potential to alter the cerebral cortex activity by olfactory stimulation. The results also suggest that olfactory perception has stimulatory effects on the function of the nervous system. In other words, it could be concluded from this study that inhalation of olfactory stimulation affected brain wave activities and mood states. Further research is needed to completely understand and describe the electrophysiological effects of different odors on the central nervous system.

• Journal of Korean Academy of Nursing
• /
• v.49 no.2
• /
• pp.126-136
• /
• 2019

Purpose: This study was conducted to evaluate the effect of breast milk olfactory stimulation on physiological responses, oral feeding progression, and body weight in preterm infants. Methods: A repeated measures design with nonequivalent control group was used. The participants were healthy, preterm infants born at a gestational age of 28~32 weeks; 12 in the experimental group and 16 in the control group. Data were collected prospectively in the experimental group, and retrospectively in the control group, by the same methods. Breast milk olfactory stimulation was provided 12 times over 15 days. The data were analyzed using the chi-square test, Mann-Whitney U test, Wilcoxon signed rank test and linear mixed models using SPSS 19. Results: The gastric residual volume (GRV) of the experimental group was significantly less than that of the control group. The heart rate, oxygen saturation, respiration rate, transition time to oral feeding, and body weight were not significantly different between the two groups. Conclusion: These findings indicate that breast milk olfactory stimulation reduces GRV and improves digestive function in preterm infants without inducing distress.

• The Journal of the Korea Contents Association
• /
• v.20 no.10
• /
• pp.199-215
• /
• 2020

The purpose of this study is to understand dogs for their happy lives. Experiment and survey were conducted to find out the effects of sensory stimulation on dogs emotions. Sensory were divided into visual, auditory, olfactory, tactile, complex and emotions were measured by the rate of deep sleep, feed intake, and heart rate. Research has shown that complex stimulation (walking) is the most positive stimulation for dog's emotions, but visual stimulation and auditory stimulation do not act as stimuli that positively change usual state of dog's emotions. Olfactory stimuli is the second best stimulation. Since olfactory stimulation is effective in maintaining a calm state without large deviation in the dog's state, it can be used as a method for relieving the dog's stress in exceptional situations when complex stimulation is not possible. On the other hand, tactile stimulation, bath, is a negative sensory stimulus that causes hypersomnia and binge eating for most dogs.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2001.05a
• /
• pp.121-124
• /
• 2001

Using ordors with the different concentration of essential oils, e studied the effect of a pleasant olfactory stimulation on physiological responses. we examined psychological response, mental task and changes in cardiac, immunity and EEG in responses to 150times solution (feel easily) and 500times solution (feel with difficulty) which of essential oil (called PCK) were diluted in propylene glycol, and neutral (water). The 150times solution that was felt pleasant produced significant differences (p<0.05) in relative power change of beta activity in the left frontal region (Fp1, F3, F7) of the brain, and heart rate (HR) deceleration after mental task. these results are consistent with substantial research that has documented cardiac and EEG responses to pleasant stimuli. What is more, 150times solution increased the concentration of s-IgA know as an index of immunity.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
• /
• v.61 no.11
• /
• pp.567-572
• /
• 2018

The sensory function of the trigeminal nerve is to provide tactile, proprioceptive, and nociceptive afference by chemical stimulation. Various physical responses of the trigeminal nerve to stimuli help to defend against harmful substances. Recently, many studies have been conducted on solitary chemoreceptor cells innervated by trigeminal nerve. Most volatile organic compounds stimulate both the olfactory and trigeminal nervous systems. In general, the trigeminal nervous system is less sensitive than the olfactory nervous system. Studies have shown that sensation of the trigeminal nerve by chemical stimulation results in inhibition of olfaction. This indicates that the olfactory and trigeminal nerves interact with each other in the central nervous system. It is important to study various noxious stimuli acting on the trigeminal nerve in modern society where environmental concerns are intensifying.