• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.684-688
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• 2008

레이더 강우와 관련한 대부분의 연구나 실무적용이 제한을 받는 이유는 레이더 반사도 등의 원시자료를 획득하기가 어려울 뿐만 아니라 이를 처리하여 수문해석에 적용하는 과정이 간단하지 않기 때문이다. 이를 해결하기 위하여 다음과 같은 내용을 연구하였다. (1) 레이더 영상자료를 실용적으로 활용하기 위한 '레이더 영상 디지털 변환법(RAIDOM)'을 연구 개발하였다. 또한 오프라인상에서도 기상청 레이더 합성 CAPPI 이미지 자료를 디지털 강우자료로 직접 변환할 수 있는 방법을 제시하였다. 이러한 기술은 앞으로 레이더 강우 연구와 레이더 강우의 활용성을 넓히는데 크게 기여할 것으로 기대된다. (2) RAIDOM 레이더 강우와 연계한 분포형 강우유출모형을 구축하였다. 본 연구에서는 DEM, 토지피복도, 토양도로부터 분포형 강우-유출모형의 매개변수를 산정하는 방법을 상세히 연구하여 제시하였다. 이러한 연구결과는 앞으로 분포형 강우유출모형에 대한 연구와 활용성을 넓히는데 기여할 것으로 기대된다. (3) 주요 관측 레이더 호우사상을 이용하여 RAIDOM 강우와 구축된 분포형 모형의 적용성을 검증하였다. 이를 위하여 먼저 강우유출자료가 체계적으로 관리되고 있는 평창강 국제수문개발계획(IHP) 시범유역의 자료를 이용하여 모형의 매개변수 보정을 수행하였다. 강우 전 하천의 기저유량과 유역의 초기함수조건을 제외한 나머지 매개변수는 유역특성을 나타내는 인자들이므로 모든 강우사상에 대하여 일정한 것으로 가정하여 매개변수 보정을 수행하였다. 6개 주요 호우사상에 대하여 보정한 결과 4개의 호우사상에 대하여 강우-유출과정을 거의 완벽하게 재현하였으며, 2개의 호우사상에 대해서는 수문곡선의 상승과 하강은 비교적 일치하나 첨두부에서 다소차이가 발생하였다. (4) 보정된 분포형 모형을 2006년 7월에 발생한 국지성 집중호우와 한강유역 중상류지역에 걸쳐 큰 홍수량을 발생시킨 2개의 호우사상에 대하여 레이더 강우자료를 적용하여 검토하였다. 검토결과 임진강유역 3개 수위관측소와 우이천수위관측소 및 중랑교수위관측소에서 모의된 홍수수문곡선은 실측치와 잘 일치하는 것으로 나타나 본 연구에서 제시한 RAIDOM과 이를 적용한 분포형 모형이 강우유출 모의를 위하여 활용될 수 있음을 보여주었다. 앞으로 태풍에 수반된 강우와 장마전선 등을 포함한 다양한 유형의 여러 가지 강우에 대한 적용을 통하여 모형의 검증과 보완을 수행하여 RAIDOM 레이더 강우와 분포형 강우유출모형을 연계한 홍수 예보 시스템으로 발전시켜 나갈 예정이다.

• Journal of the Microelectronics and Packaging Society
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• v.14 no.4
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• pp.43-48
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• 2007

This study is focused on the effect of the surface properties for the post electrode, which is used in pad formation consisted of SMT such as IC, passive component, combined with fired LTCC substrate, We carried out the surface microstructure of sintered electrode and the basic reliability evaluations with sample fired by microwave sintering to solve the problems occurred in post electrode by electric sintering. We evaluated surface densification status of post electrode according to various conditions of microwave sintering. In additions, it is obtained strong effect on blister improvement of post electrode because of over-sintering and the insufficient out gas in bum out process. As a result of adhesion strength, we confirmed $44.3N/mm^2$ in microwave sintering and $34.5N/mm^2$ in electric sintering, respectively. This result will be used for the basic reliability test. Finally, microwave sintering seems to be economic in process time with 30 min compared to electric sintering with 10 hr. In terms of Mass production and efficiency, microwave sintering are excepted to be higher than electric sintering.

• Biomolecules & Therapeutics
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• v.22 no.4
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• pp.347-354
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• 2014

Larrea nitida is a plant that belongs to the Zygophyllaceae family and is widely used in South America to treat inflammatory diseases, tumors and menstrual pain. However, its pharmacological activity remains unclear. In this study we evaluated the property of selective estrogen receptor modulator (SERM) of Larrea nitida extracts (LNE) as a phytoestrogen that can mimic, modulate or disrupt the actions of endogenous estrogens, depending on the tissue and relative amount of other SERMs. To investigate the property of SERM of LNE, we performed MCF-7 cell proliferation assays, estrogen response element (ERE)-luciferase reporter gene assay, human estrogen receptor (hER) binding assays and in vivo uterotrophic assay. To gain insight into the active principles, we performed a bioassay-guided analysis of LNE employing solvents of various polarities and using classical column chromatography, which yielded 16 fractions (LNs). LNE showed high binding affinities for $hER{\alpha}$ and $hER{\beta}$ with $IC_{50}$ values of $1.20{\times}10^{-7}$ g/ml and $1.00{\times}10^{-7}$ g/ml, respectively. LNE induced $17{\beta}$-estradiol (E2)-induced MCF-7 cell proliferation, however, it reduced the proliferation in the presence of E2. Furthermore, LNE had an atrophic effect in the uterus of immature rats through reducing the expression level of progesterone receptor (PR) proteins. LN08 and LN10 had more potent affinities for binding on $hER{\alpha}$ and ${\beta}$ than other fractions. Our results indicate that LNE had higher binding affinities for $hER{\beta}$ than $hER{\alpha}$, and showed SERM properties in MCF-7 breast cancer cells and the rat uterus. LNE may be useful for the treatment of estrogen-related conditions, such as female cancers and menopause.

• Journal of The Korean Society of Clinical Toxicology
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• v.4 no.1
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• pp.32-43
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• 2006

Purpose: Toxic Exposure Surveillance System (TESS) is widely used for poisoning data collection and making a counterplan. But, there were few reports about poisoning data collection using TESS in Korea. The aim was to collect poisoning data using TESS report form and investigate the recognition of emergency physician about the necessity of TESS as preliminary survey. Methods: Retrospectively, we gathered data from hospital records about the patient who admitted hospital emergency room due to poisoning. Date were gathered by paper and/or web client system report form in patients recruited by ICD-10 codes Results: From Jun 2004 to May 2005,3,203 patients were enrolled in 30 hospitals and their mean age was $44.9{\pm}20.3years$ old(male: female = 1,565: 1,638). The most frequent site of exposure was their own residence (73.2%, 2,345/3,203) and most of reported patients were older than 20 years(89.7%, 2,871/3,203). Frequent substances involved in poisoning were medication(41.9%) and pesticide(33.3%). Intentional poisoning was 60.7%(1,954). In fatality, overall frequency was 5.1%(162/3,203) and the most frequent route of exposure was ingestion(96.3%, 156/162) and the most frequent substance was pesticide(85.2%, 138/ 162). Antidotes were administered in 202 patients(2-PAM, atropine, antivenin, N-acetylcystein, vitamin K, flumazenil, ethanol, methylene blue, naloxone, calcium compound). 19 of 20 emergency physicians agreed with necessity of TESS. Conclusion: Data collection using TESS report form showed preliminary poisoning events in Korea. Frequent poisoning substance were medication and pesticide. The fatality was mainly related with pesticide ingestion. Many doctors in emergency room recognized the necessity of TESS.

• Economic and Environmental Geology
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• v.39 no.5 s.180
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• pp.567-581
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• 2006

The Au-Ag lode deposits in South Korea are closely associated with the Mesozoic granitoids. Namely, the Jurassic deposits formed in mesozonal environments related to deep-seated granitoids, whereas the Cretaceous ones were developed in porphyry-related environments related to subvolcanic granitoids. The time-space relationships of the Au-Ag lode deposits in South Korea are closely related to the changing plate motions during the Mesozoic. Most of the Jurassic auriferous deposits (about $165{\sim}145$ Ma) show fluid characteristics typical of an orogenic-type gold deposits, and were probably generated in a compressional to transpressional regime caused by an orthogonal to oblique convergence of the Izanagi Plate into the East Asian continental margin. On the other hand, strike-slip faults and caldera-related fractures together with subvolcanic activity are associated with major strike-slip faults reactivated by a northward (oblique) to northwestward (orthogonal) convergence, and probably have played an important role in the formation of the Cretaceous Au-Ag lode deposits (about $110{\sim}45$ Ma) under a continental arc setting. The temporal and spatial distinctions between the two typical Mesozoic deposit styles in South Korea probably reflect a different thermal episodes (i.e., late orogenic and post-orogenic) and ore-forming fluids related to different depths of emplacement of magma due to regional changes in tectonic environment.

• Journal of Gastric Cancer
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• v.18 no.1
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• pp.30-36
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• 2018

Purpose: We investigated complications after laparoscopic sentinel basin dissection (SBD) for patients with gastric cancer who were enrolled in a quality control study, prior to the phase III trial of sentinel lymph node navigation surgery (SNNS). Materials and Methods: We analyzed prospective data from a Korean multicenter prerequisite quality control trial of laparoscopic SBD for gastric cancer and assessed procedure-related and surgical complications. All complications were classified according to the Clavien-Dindo Classification (CDC) system and were compared with the results of the previously published SNNS trial. Results: Among the 108 eligible patients who were enrolled in the quality control trial, 8 (7.4%) experienced complications during the early postoperative period. One patient with gastric resection-related duodenal stump leakage recovered after percutaneous drainage (grade IIIa in CDC). The other postoperative complications were mild and patients recovered with supportive care. No complications were directly related to the laparoscopic SBD procedure or tracer usage, and there were no mortalities. The laparoscopic SBD complication rates and patterns that were observed in this study were comparable to those of a previously reported trial. Conclusions: The results of our prospective, multicenter quality control trial demonstrate that laparoscopic SBD is a safe procedure during SNNS for gastric cancer.

• Journal of Korean Tunnelling and Underground Space Association
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• v.22 no.5
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• pp.563-574
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• 2020

Currently, road tunnels and railroad tunnels are building smoke control systems to emit toxic gases and smoke from fires. Among the various smoke control systems, the transverse smoke control system has the disadvantage that air supply or exhaust is performed on only half of the cross-section, rather than air supply or exhaust on the entire cross-section of the tunnel as air is supplied or exhausted by partitioning the wind path. Therefore, this study analyzed the effect of exhaustion through numerical analysis and scaled model tests on the zoning smoke control system, which improved the limitations of the transverse smoke control system. As a result of the scaled model test, the transverse ventilation system exhibited a 25.6% smoke control rate based on the state where no smoke was controled, and zoning smoke control system showed a smoke control rate of 40.8%. In addition, as a result of numerical analysis, it was found that transverse ventilation system did not control fire smoke spreading from the tunnel and continued to spread. On the other hand, zoning smoke control system was found to be smoke controled within a certain section due to the air curtain effect and the flue gas effect.

• Journal of Korean Neurosurgical Society
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• v.30 no.10
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• pp.1200-1209
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• 2001

Objective : A thorough understanding of the related venous structure is mandatory for successful removal of the petroclival meningiomas. This study was planned to investigate the guideline for safe ligation and incision of transverse or sigmoid sinuses and the importance of drainage pattern of vein of $Labb{\acute{e}}$ in surgical removal of petroclival meningiomas. Patients and Methods : The authors reviewed the venogram of the consecutive 37 cases of petroclival meningiomas and retrospectively analyzed their surgical findings. The drainage pattern of confluence of Herophili was classified as Type A(confluent & equal on both sides), Type B(confluent & non-dominant on tumor side), Type C(confluent & dominant on tumor side) and Type D(unilateral drainage only) as these findings gave the information on safe ligation and resection of the sinus. Usefulness of intraoperative test clamping of sinus for safe ligation was also reviewed. The vein of $Labb{\acute{e}}$ was analyzed with respect to its draining point and its collaterals to other superficial veins. Results : Contraindications of the sinus ligation and resection according to the drainage pattern at the confluence of Herophili were Type C(n=10, 27%)and Type D(n=4, 11%). Patients with Type A(n=12, 32%)and Type B(n=11, 30%) were tolerable to sinus ligation ipsilateral to tumor, if the test clamping proved to be safe. Identification of no brain swelling, after intraoperative test clamping of the sinus for more than 30 minutes performed in 7 out of 11 cases, was a reliable indicator of safe sinus ligation. The drainage pattern of the vein of $Labb{\acute{e}}$, especially low-lying type, could predict the possibility of postoperative hemorrhage and infarction. Its drainage into tentorium or superior petrosal sinus, however, made the transtentorial approach impossible, leading to restricted operative field. Conclusion : For a successful removal of the petroclival meningiomas preoperative venogram should be examined carefully. The extent of exposure in a planned approach can be estimated by analyzing the variation of sinuses and the drainage pattern of vein of $Labb{\acute{e}}$.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.12 no.4
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• pp.47-71
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• 2009

The resource plants of northern region in Gapyeong-gun were investigated 7 times from Apr. 2007 to Oct. 2007. In the result of survey, the flora of this area, depend on voucher specimens, consist of 480 taxa totally; 94 families, 286 genera, 412 species, 4 subspecies, 52 varieties and 12 forms. The Resource plants in this area were categorized by their use into edible 177, pasturing 136, medicinal 124, stainable 69, ornamental 133, afforest 24, timber 10, fiber 6, industrial 2 taxa and unknown use plants 72, respectively. There were remarkable plants such as 14 taxa of Korean endemic plants, 85 taxa of specific plants which were designated by the Ministry of Environment, and 12 taxa of rare and endangered plants of Korea Forest Service. Furthermore, 22 taxa of naturalized plants 4.6% were also observed in this area and Urban Index (UI) was 8.2%. The vegetation status of investigated area was comparatively well conserved, but the degree of UI could be increased rapidly by the climbers, development of forest road. Therefore, the systems for conservation need to prepared for the effective management of forest, and the special plans need to control the number of climbers and visitors.

• Weed & Turfgrass Science
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• v.2 no.3
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• pp.318-321
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• 2013

National Academy of Agricultural Science and eight province Agricultural Research & Extension Services investigated the occurring area of herbicide resistant weeds in paddy field of Korea. In order to estimate the occurring areas of herbicide resistant weeds, we collected paddy soils randomly from 3,200 sites in 2011 and 2012, and treated 30 kg $ha^{-1}$ of pyrazosulfuron-ethyl+pyriminobac-methyl GR to the paddy soil. 176,870 ha, approximately 22.1% of cultivated area excluding organic and eco-friendly cultivated area, was estimated to be infested by SUherbicide resistant paddy field weeds. Several species of resistant weeds were occurred at Jeonranam-do with 44.3%, followed by 30.5% at Chungchungnam-do, 27.8% at Chungchungbuk-do, and 24.5% at Jeonrabuk-do, respectively. Monochoria vaginalis showed the highest distribution with 57,018 ha, 32.2% followed by Scirpus juncoides, and Lindernia procumbens, respectively.