• 한방안이비인후피부과학회지
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• 제26권1호
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• pp.63-74
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• 2013

Objective : Low level laser therapy(LLLT) is conjugated many different diseases such as skin disease, nervous system disease, cardiovascular disease, etc. This study was tried to survey the conjugation of LLLT in field of ophthalmology, otolaryngology and dermatology of Korean Medicine. Methods : In this study, LLLT deal with the field of ophthalmology, otolaryngology and dermatology was searched at Pubmed and NDSL. We searched Pubmed and NDSL with the title "Laser Therapy and Low-Level" for the last 10 years and analyzed disease, laser type, sample size, effect, journal and year. Results : Using Pubmed and NDSL, 8 treatises were researched. About 8 treatises, 7 treatises were papers in field of dermatology, 1 treatise was ophthalmology. And about 8 treatises, 6 treatises were foreign papers and 2 treatises were domestic papers on clinical application of laser status. Mainly used type of laser was a He-Ne laser and Diode laser. The diseases were ocular hypertension, acne, ulcers in patients with leprosy sequelae, freckles, segmental-type vitiligo lesions, diabetes-linked skin lesion, facial skin melanin and elasticity, atopic dermatitis symptom. As a result, we found that treat group had more improvement than control group in 7 of the 8 treatises, that treat group had no difference control group on effect significantly only 1 treatise. Conclusions: As therapeutic tool, LLLT's application range is very wide in the field of ophthalmology, otorhinolaryngology, and dermatology. Keep up with the increasing interest of domestic and foreign about laser therapy, clinical tries on the use of laser will be studied steadily. It is necessary to have sustained attention and research on the point of view of the Korean Medicine.

• 한국가금학회지
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• 제46권4호
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• pp.263-269
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• 2019

IBV는 전세계적으로 양계산업에 문제시되고 있는 호흡기성 질병으로 육계 및 산란계의 생산성에 큰 영향을 미치고 있다. 본 연구는 2018년도에 분리된 3개의 IBV의 병원성을 확인하였다. 동물실험을 통해서 염증정도, 섬모소실도 그리고 폐사율의 결과를 바탕으로 2018년도 분리주인 QX-like IBV형은 병아리에게서 충분한 병원성을 지닌 것을 확인하였다.

• 한방안이비인후피부과학회지
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• 제33권2호
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• pp.1-11
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• 2020

Objectives : The purpose of this study was to analyze and report status of Korean Medicine Ophthalmology patients who did funduscopy examination. Through this, we hope that the development of our diagnosis and treatment. Methods : From June 1, 2010 to May 31, 2019, Based on the electronic medical records of patients who had funduscopy examination at Korean Medicine Ophthalmology, Busan University Korean Medicine Hospital, the gender, age, visiting motives and paths, diagnosis, examination number of years, other eye examinations and treatments method were summarized and analyzed. Results : 463 patients were able to check the electronic medical records. They were 283 females and 180 males. The mean age of the patients was 51.5 years and elderly patients who 50s and 60s were 49.3% of whole patients. The most common motives for Korean Medicine Ophthalmology visitation was 'combination treatment with other department in Korean Medicine Hospital'. Outer eye diseases were 283 cases, inner eye diseases were 198 cases. Dry eye syndrome, asthenopia, visual discomfort, conjunctivitis, and eye discomfort were most common in the outer eye diseases. Cataracts, Vitreous floater, Macular Degeneration, Glaucoma and Ocular Pain were most common in the inner eye disease. The most common parts of outer eye diseases were Conjunctival, lacrimal gland, paralytic, corneal, eyelid and front uveal, scleral disease and then in inner eye diseases parts, Retinal, lens, vitreous, glaucoma, optic nerve, behind uveal, choroid disease were most common. The number of funduscopy examination was ups and downs. Herbal medicine was the most common used. Conclusions : The funduscopy examination is essential for diagnosis and treatment of eye disease. We hope that the use of fundus examination and other ophthalmologic examination will be expanded soon in Korean Medicine Ophthalmology.

• Journal of Genetic Medicine
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• 제17권1호
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• pp.39-42
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• 2020

The Senior-Loken syndrome was first described in 1961 as an oculo-renal disease consisting of familial juvenile nephronophthisis and Leber congenital amaurosis. It is a rare autosomal recessive disorder with a prevalence of 1:1,000,000 caused by mutations in nine genes (NPHP 1-8 and NPHP 10). Ocular manifestations (e.g., photophobia, nystagmus, and extreme hyperopia) occur within the first few years of life while renal manifestations (e.g., formation of multiple cysts impairing kidney function and end-stage renal disease) appear in late childhood to adolescence. Here, we report a case of a Filipino male presenting with rotatory nystagmus and progressive deterioration of vision since childhood. He had congenital amaurosis and juvenile nephronophthisis that progressed to end stage renal disease by age 19. All laboratory and imaging findings were consistent with chronic kidney disease. Molecular genetic testing of ciliopathy-related genes was performed revealing a homozygous mutation in exon 11 of the IQCB1/NPHP5 gene, c.1090C>T (p.Arg364^⁎). This sequence change created a premature translational stop signal resulting in a truncated protein product, nephrocystin-5 and its consequent loss of function. His symptoms eventually improved with initiation dialysis. The prognosis of Senior-Loken syndrome remains dismal and a high index of suspicion, early diagnosis and timely intervention of renal complications are warranted.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.103.6-103
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• 2001

Glaucoma is an eye disease which is caused by abnormal high IOP (Intra Ocular Pressure) in the eye. High IOP is caused by the aqueous humor which is produced consistently but not drained due to the malfunction of the trabecular system which has a role of draining the aqueous humor into the venous system. Currently, there are some methods to treat glaucoma, Among these, the use of implants is increasing in these days due to many problems in other methods. However, conventional implants are passive implants and have critical disadvantage. Therefore, it is needed to develop a new implant using MEMS structure which is capable of controlling the IOP actively and copes with personal difference of patients. An active glaucoma implant consists of the valve actuator, pressure sensor, controller, and power supply. In this paper the valve actuator is considered. We make experiments and simulations with the fabricated ...

• 대한의용생체공학회:의공학회지
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• 제8권1호
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• pp.81-86
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• 1987

An image feature extraction method for the low contrast fluoresceln angiogram in dlabetes was studied. To obtain effective image segmentation, an adaptive local difference image is generated and relaxation process are applied to this difference Image. By the use of distance transformed data with segmented image, shape and location of feature regions were obtained. It was shown that the location and shape descriptions of Impaired blood vessel networks and retinal regions are can he utilized for the diagnosis of diabetes and other disease.

• 한국임상수의학회지
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• 제37권5호
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• pp.292-294
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• 2020

A 14-year-old castrated male Persian cat presented with epiphora, blepharospasm, brownish ocular discharge, corneal neovascularization, and corneal opacity in the left eye. Medial lower eyelid entropion was diagnosed through an ophthalmic examination. Since the cat was old and suffered from chronic kidney disease, we decided to perform a hyaluronic acid (HA) subdermal filler injection without general anesthesia rather than surgical correction. After topical anesthesia by lidocaine jelly and disinfection, HA filler was injected into the medial lower eyelid under minimal physical restraint. At the last follow-up 139 days later, lower eyelid entropion was not observed and related clinical signs disappeared. Therefore, HA subdermal filler can be an effective intervention for the treatment of entropion in cats.

• 한방안이비인후피부과학회지
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• 제11권1호
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• pp.292-299
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• 1998

I examined 54 patients who had been diagnosed as dry eye or had experienced symptoms of dry eye such as foreign body sense, dry sense, sore sense, pain, etc. and had some results. The results were as follows; 1. In sex, there were more females than males. 2. The age was examined from 19 years to 70 years and 51-60 years was the most. 3. In duration of symptoms, 1-5 years was taken most of the patients. 4. In blood type, O type was dominant comparing other blood types. 5. In warm and cold preference cold was more than warm or tepid. 6. In associated ocular & systemic disease chronic gastritis was the most and the next was chronic conjunctivitis. 7. In main symptoms foreign body sense was the most of them 8. In prescription Gamisamultang(加味四物湯) was most frequently administered to the patients.

• 대한시과학회지
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• 제20권4호
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• pp.497-504
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• 2018

목적 : 백내장 환자를 대상으로 수술 전과 후의 안구표면의 온도변화 양상을 열화상카메라의 서모그래피를 이용하여 연구 하고자 하였다. 방법 : 본 연구는 백내장 수술을 받은 환자 50-79세까지 75명 75안의 환자 군을 대상으로 하였다. 과거에 굴절교정수술, 각막관련 수술을 받은 자와 콘택트렌즈를 사용하는 자, 눈물관 이상자, 전신질환 치료 약물을 복용하는 자 등 눈물분비와 눈물막에 영향을 줄 수 있는 자는 연구 대상자에서 제외하였고 눈물막파괴시간 검사(Tear Break Up Time, BUT), 쉬르머 검사(Schirmer's Test), 맥모니테스트(Mcmonnies questionnaire)를 시행한 후 열화상카메라(Cox CX series, Answer., Korea)를 이용하여 안구표면의 온도변화를 실시간으로 측정하였다. 결과 : 전체 대상자의 술 전 안구표면 온도는 $35.20{\pm}0.54^{\circ}C$이었고 술 후에는 $35.30{\pm}0.53^{\circ}C$로 표면온도가 상승하였으나 유의한 차이를 보이지 않았다. 안구표면 온도변화는 술전에서 $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$)에서 술 후 $-0.18{\pm}0.07{\Delta}$ ($^{\circ}C/sec$)로 통계학적으로 유의한 결과를 나타냈다. 연령 별 비교에서는, 50 대군은 백내장 술 전 대상자의 안구표면 온도변화가 $-0.14{\pm}0.09{\Delta}$ ($^{\circ}C/sec$)에서 $-0.19{\pm}0.05{\Delta}$ ($^{\circ}C/sec$)으로 나타났고 60 대군에서는 $-0.12{\pm}0.08{\Delta}$ ($^{\circ}C/sec$)에서 $-0.15{\pm}0.07{\Delta}$ ($^{\circ}C/sec$)으로 나타났으며 70 대군에서는 술 전 대상자의 안구표면 온도변화는 $-0.12{\pm}0.08{\Delta}$($^{\circ}C/sec$)에서 $-0.18{\pm}0.07{\Delta}$($^{\circ}C/sec$)으로 전 연령에서 모두 유의한 안구표면 온도변화를 보였다. 결론 : 백내장 술 후에는 안구건조증 평가지표가 모두 감소하였고 안구표면 온도변화가 유의함을 보였다. 안구표면의 서모그래피 기술은 비침습적으로 안구건조증을 평가하는데 용이하였고 객관적으로 수치화할 수 있는 장점이 있어 다양한 안구건조증 연구에 활용 될 것으로 기대된다.

• Journal of International Society for Simulation Surgery
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• 제1권1호
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• pp.7-12
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• 2014

Purpose Surgical correction of various occular problems which do not have visual problem in plastic surgical area is to normalize the appearance of the face by restoring the normal position of orbit and eyeball. With development of surgical technique, the orbit can be restored exactly in trauma patient and can be moved totally in hypertelorism, as an example of congenital disease. All these surgeries are based on the hypothesis that the position of oclular glove moves in the plane in a quantitatively predictable reationship to osseous orbit movement. However, no studies have critically evaluated between the change of periorbital soft tissue and the outcome of the surgical correction, because there is no method of objective, quantitave evaluation of the periorbital soft tissue. Method Author suggest the methodology for quantitative assessment of ocular and periocular fat changes using the manipulation of digital images of computed tomographic scan. Results The method was allowed to evaluate inter-dacryon distance, inter-centroid distance, movement of the medial orbital wall, movement of the lateral orbital wall, alteration of thickness of the lateral periorbital fat as indicator of movement of the orbital wall and orbit in the patient with congenital periorbital anomaly and postoperative periorbital surgery. The goal of surgical correction of various occular problems which do not have visual problem in plastic surgical area is to normalize the appearance of the face by restoring the normal position of orbit and eyeball. With development of surgical technique, the orbit can be restored exactly in trauma patient and can be moved totally in hypertelorism, as an example of congenital disease. All these sugeries are based on the hypothesis that the position of oclular glove moves in the plane in a quantitatively predictable relationship to osseous orbit movement. However, no studies have critically evaluated between the change of periorbital soft tissue and the outcome of the surgical correction, because there is no method of objective, quantitave evaluation of the periorbital soft tissue. In this report, author suggest the methodology for quantitative assessment of ocular and periocular fat changes using the manipulation of digital images of computed tomographic scan. Conclusion The method suggested is objective and accurate method in measurement of the orbital contents. It takes time and is not easy to do, however, this kind of measurement for fine structures will be more easily available in near future.