• Journal of The Korean Society of Clinical Toxicology
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• v.2 no.2
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• pp.67-71
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• 2004

Arsenic poisoning has three types of poisoning. First, acute arsenic poisoning is usually caused by oral intake of large amount of arsenic compound with purpose of homicide or suicide. Second, chronic arsenic poisoning is caused by inhalation of arsenic in the occupational setting or by long-term oral intake of arsenic-contaminated well water. Third, arsine poisoning occurs acutely when impurities of arsenic in non-ferrous metal react with acid. Clinical manifestation of acute arsenic poisoning is mainly gastrointestinal symptoms and cardiovascular collapse. Those of chronic poisoning are skin disorder and cancer. Arsine poisoning shows massive intravascular hemolysis and hemoglobinuria with acute renal failure. Exposure evaluation is done by analysis of arsenic in urine, blood, hair and nail. Species analysis of arsenic is very important to evaluate inorganic arsenic acid and mono methyl arsenic acid (MMA) separated from dimethyl arsenic acid (DMA) and trimethyl arsenic acid (TMA) which originate from sea weed and sea food. Treatment with dimercaprol (BAL) is effective in acute arsenic poisoning only.

• Safety and Health at Work
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• v.3 no.1
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• pp.11-16
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• 2012

Lead poisoning is one of the earliest identified and most known occupational disease. Its acute effects have been recognized from antiquity when this condition principally afflicted manual workers and slaves, actually scarcely considered by the medicine of that time. The Industrial Revolution caused an epidemic of metal intoxication, urging scientists and physician of that period to study and identify specific symptoms and organ alterations related to chronic lead poisoning. During the 20th century, the acknowledgment of occupational and environmental toxicity of lead fostered public awareness and legislation to protect health. More recently, the identification of sub-clinical effects have greatly modified the concept of lead poisoning and the approaches of medicine towards this condition. Nowadays, lead poisoning is rarely seen in developed countries, but it still represents a major environmental problem in certain areas. Consequently, it may appear as a paradigm of "occupational and environmental disease," and the history of this condition seems to parallel the historical development of modern "Occupational and Environmental Health" as a more complete medical discipline.

• Annals of Occupational and Environmental Medicine
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• v.34
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• pp.19.1-19.9
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• 2022

Background: It is widely known that carbon dioxide (CO₂) arc welding generates carbon monoxide (CO). However, to the best of our knowledge, no case reports have been published regarding CO poisoning in CO₂ arc welders. Therefore, we aimed to report a case of CO poisoning-induced encephalopathy in a CO₂ arc welder in the Republic of Korea to inform about the dangers of CO exposure among CO₂arc welders. Case presentation: A 40-year-old man working as a CO₂ arc welder for 15 years visited a local hospital with a tremor, involuntary urination, and speaking gibberish, on April 9, 2019. He stated that he had intermittent headache and forgetting symptoms for the last 5 years, and had been lost on the way to work several times. On April 9, 2019, he was diagnosed with CO poisoning-induced encephalopathy through brain magnetic resonance imaging. He received hyperbaric oxygen therapy, and some of his symptoms improved. According to the exposure assessment of his work environment, he was continuously exposed to high concentrations of CO for 15 years while operating CO₂ arc welding machines. Conclusions: After evaluating the patient's work environment and evaluating his medical history, we concluded that his encephalopathy was caused by CO exposure during CO₂ arc welding. Thus CO₂ arc welders must be aware of the risk of CO poisoning and strive to avoid CO exposure.

• Safety and Health at Work
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• v.10 no.3
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• pp.265-274
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• 2019

Background: Methyl alcohol poisoning in mobile phone-manufacturing factories during 2015-2016 was caused by methyl alcohol use for cleaning in computerized numerical control (CNC) processes. To determine whether there were health complications in other workers involved in similar processes, the Occupational Safety and Health Research Institute conducted a survey. Methods: We established a national active surveillance system by collaborating with the Ministry of Employment and Labor and National Health Insurance Service. Employment and national health insurance data were used. Overall, 12,048 employees of major domestic mobile phone companies and CNC process dispatch workers were surveyed from 2016 to 2017. We investigated methyl alcohol poisoning by using the national health insurance data. Questionnaires were used to investigate diseases due to methyl alcohol poisoning. Results: Overall, 24.9% of dispatched workers were employed in at least five companies, and 23.9% of dispatched workers had missing employment insurance history data. The prevalence of blindness including visual impairment, optic neuritis, visual disturbances, and alcohol toxicity in the study participants was higher than that reported in the national health insurance database (0.02%, 0.07%, 0.23%, and 0.03% versus 0.01%, 0.07%, 0.13%, and 0.01%, respectively, in 2015). Moreover, 430 suspicious workers were identified; 415 of these provided an address and phone number, of whom 48 responded (response rate, 11.6%). Among the 48 workers, 10 had diseases at the time of the survey, of whom 3 workers were believed to have diseases related to methyl alcohol exposure. Conclusion: This study revealed that active surveillance data can be used to assess health problems related to methyl alcohol poisoning in CNC processes and dispatch workers.

• Journal of Environmental Health Sciences
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• v.46 no.5
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• pp.565-575
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• 2020

Objective: South Korea still lacks systematic national poisoning data collection or a poison control center (PC). The objectives of this study are to provide estimates of poisoning incidents in South Korea and to stress the necessity of a national poisoning surveillance framework managed by a national PC. Method: The number of poisoning incidents was estimated based on the 2018 annual report of the American Association of Poison Control Centers' National Poison Data System (NPDS). Our estimation of poisoning data was classified according to age group, reason for poison exposure, and case management site. Results: Total poisoning cases estimated numbered 326,636, which is tantamount to 631 cases per 100 thousand. Poisoning cases among those younger than five years old accounted for 71.7% in the United States. Fatal poisoning cases were estimated to be 210.63 (95% CI: 199.70-222.15). Non-intentional poisoning cases (250,378 cases, 95% CI: 249,992-250,764, 76.7%) were estimated to be far higher than intentional cases (62,399 cases, 95% CI: 62,207-62,593, 19.1%). Conclusion: Our results can be used to suggest the necessity of producing national poisoning data and establishing a PC despite the uncertainty of estimation.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.33 no.2
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• pp.188-205
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• 2023

Objectives: Methanol poisoning accidents in smartphone parts manufacturing facilities were analyzed using a systemic accident analysis method, and the necessity and possibility of the application of this systemic method in the field of occupational health were reviewed. Methods: A STAMP model for accident analysis was created based on the previously published literature. CAST analysis was performed to find the causal factors of the components and between the components. Results: The STAMP model visually showed the abstract and complex system control structure. The CAST analysis results could include all the causal factors from the previously published literature, and presented them holistically. Additional causal factors that were not presented in the literature were found. Conclusions: The holistic accident analysis results in this study will be helpful to establish comprehensive measures to prevent methanol or other chemical poisoning accidents. Therefore, it will be necessary to use systemic accident analysis methods in the field of occupational health.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.27 no.3
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• pp.149-162
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• 2017

Objectives: Six cases of non-oral occupational methanol poisoning were found in mobile phone parts manufacturers in South Korea during the period from 22 January 2016 to 5 October 2016. We conducted this study to determine the cause of the accident including social environment factor. Methods: We interviewed the cases. Based on that, we described this poisoning accident narratively and arranged the evolution of the accident in chronological order. We used the Haddon matrix method to investigate the cause of the accident. Results: It was found that six cases were all dispatched workers who were under poor working condition including working time exceeded 12 hours a day, not given basic occupational health and safety information etc. Occupational disease associated with dispatched work was difficult to be reported. 2 cases were not able to identify the cause of the disease within one year. Conclusions: In short, the direct cause of the poisoning accident was that workers were exposed to high concentration of methanol(over 1,000 ppm). One of the main fundamental cause is that dispatched worker is rampant in the supply chain of mobile phone production. To protect dispatched workers, appropriate occupational safety health measures are needed urgently.

• KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
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• v.2 no.3 s.5
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• pp.29-35
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• 1995

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.33 no.4
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• pp.517-527
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• 2023

Objectives: We examine cases of chemical poisoning that occurred in the cleaning of metal parts and the regulations on halogenated solvents in other countries and propose regulations necessary to prevent chemical poisoning from halogenated solvents. Methods: We collected cases of chemical poisoning through the website of the Korea Occupational Safety and Health Agency. A review of the literature was conducted focusing on regulations related to halogenated solvents in the United States and the European Union, particularly for cleaning metal parts. Among the Material Safety Data Sheets submitted to the government, MSDS containing eleven substances were extracted to confirm the composition and product use. We investigated cleaning methods for metal parts used in South Korea. For the hazard classification, the European Chemicals Agency or Japan's NITE's website was used. Results: In the case of poisoning, the cleaning methods involving trichloromethane were dipping and dry, which was not found in the literature. It was confirmed that many halogenated solvents and dimethyl carbonate were used for metal cleaning in South Korea. In vapor degreasing using TCE in the USA, even if the facility is strictly managed, such as by installing cooling coils in open cleaning facilities, the risk of exposure to TCE is considered to be not only carcinogenic but also a concern for acute and chronic effects. In comparison, exposure through Korean work methods such as dipping and drying operations is inevitably much higher. Conclusions: The transition to water-based cleaning with low-hazard chemicals should be a priority in the cleaning process. In the case of metal parts that require precise cleaning, if the use of a halogenated solvent is inevitable, a closed degreasing facility should be used to minimize exposure. The current regulations in the Occupational Safety and Health Act, the Chemical Substances Control Act, and the Air Environment Conservation Act do not require cleaning facilities to minimize emissions. To protect the health of workers using halogenated solvents to clean metal parts, regulations that require a fundamental reduction in exposure will be necessary.

• Journal of Environmental Health Sciences
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• v.48 no.1
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• pp.19-27
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• 2022

The industrial development and socioeconomic structures of a society are inextricably linked to occupational accidents and diseases. Since the 1970s, a series of major occupational diseases have occurred in South Korea, such as mercury poisoning in Munsong-myeon, carbon disulfide poisoning at Wonjin Rayon, and leukemia at Samsung Electronics. These incidents have caused us to take a critical look at the level of worker safety and health management within companies and the government. These serve as symbolic and representational events. Doctors, lawyers, and labor activists concerned about employee safety and lives came together for years to struggle with the government and industry in order to determine what caused the diseases and to obtain compensation for victims. They finally achieved recognition for occupational diseases and recompense for losses. It is difficult to find similar cases to the baby powder asbestos talc cases and the radon bed case internationally, or there is no case where such a large number of consumers have been potentially harmed. It is also difficult to prove that the damage took place due to the victims' diverse geographic locations and ages, as well as the disease's long incubation period. Based on this premise, businesses and the government have been apathetic in acknowledging these diseases and compensating for damages, with few practical outcomes. Furthermore, unlike the large-scale occupational disease cases, only a few people including expert groups were organized and actively participated in the settlement of these issues, so it remains unfinished business for our society to address.