• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.163-173
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• 2011

Purpose: To show the clinical aspects in outpatients who visited Oriental Obstetric & Gynecology Clinic Methods: We studied 7141 patients who visited Oriental Obstetric & Gynecology Clinic from 2008 to 2010. Results: 1. The total patients and the percentage of new patients increased every year. 2. The age distribution showed over 60% in 20~49. 3. The percentage of Oriental Ob&Gy patients decreased with 55% in 2008, 28% in 2009, 29% in 2010. 4. The distribution of oriental diagnosis showed 55.4% in Ob&Gy, 19.2% in musculoskeletal system, 6% digestive system and respiratory system neuropsychiatry in 2008. And 30.6% in musculoskeletal system, 28.5% in Ob&Gy, 10.9% neuropsychiatry in 2009. And 29% in musculoskeletal system, 28.1% in Ob&Gy, 11.1% in heart system in 2010. 5. The most commonly used herbal medicine was Ikgibohyeltang. Conclusions: We hope these results could be helpful to diagnosis and treatment of oriental Ob&Gy patients.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1651-1655
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• 2012

Background: Our aim was to investigate the efficacy of the Pap test in combination with the ThinPrep cytological test (TCT) in screening for cervical cancer in China. Design: From March 2006 to October 2008, 988 women with the mean age $46.4{\pm}10.5$ years (range, 23-80 years) were recruited to receive cervical cancer screening. Pap test results ${\geq}$ grade III and TCT findings ${\geq}$ ASCUS/AGUS were considered abnormal. Subjects with a Pap test result ${\geq}$ grade IIb received TCT. Colposcopy and biopsies were performed in all participants, and final diagnosis was based on pathological findings. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and Youden index for predicting CIN I or above were determined. Results: The sensitivity, specificity, PPV, NPV and Youden index of the Pap test were 43.1%, 97.2%, 70.0%, 91.9%, and 40.3%, respectively. The same values for TCT in predicting CIN were 80.0%, 63.2%, 16.0%, 97.3%, and 43.2%, respectively. The two tests in combination gave values for predicting CIN of 64.8%, 87.6%, 43.6%, 94.4%, and 53.5%, respectively. Combined testing exhibited the highest Youden index (53.4%). Conclusion: The Pap test with a reduced threshold in combination with the TCT has high sensitivity and high specificity in screening for cervical cancer.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.145-153
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• 2010

Purpose: Sjogren's syndrome is a type of autoimmune disease and characterized by the keratoconjunctivitis sicca, xerostomia, dryness of mouth & eyes and rheumatoid arthritis or another connective tissue disease. In the Traditional Korean Medicine, there is few report to diagnose and treat Sjogren's syndrome. Methods: The subject was a typical Sjogren's syndrome in 48-year old women whose complaints were dryness of mouth and eyes, severe general myalgia. The author treated her with acupuncture and herbal medicine therapy, then evaluated with MMQ score, XQS grade and VAS score on a regular basis. Results: After treatment, clinical symptoms were improved, MMQ score and XQS grade were decreased. Conclusion: The Traditional Korean Medical Therapy combined acupuncture with herbal medicine relieves the symptom of Sjogren's syndrome.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.4
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• pp.194-204
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• 2009

Purpose: When pregnant women get symptom like pain, because of fear of using analgesic drugs and X-ray test during pregnancy, pain is nevertheless often left. This study was to report the clinical application and safety of oriental treatment to low back pain and pelvic pain caused by traffic accident during pregnancy. Methods: We experienced seven patients who suffered from low back pain and pelvic pain caused by traffic accident during pregnancy. During their admission, we treated with acupuncture, cupping therapy and herbal medicine. We checked the symptoms during admission at progress note, and follow up by phone call. Results: The degree of low back pain and pelvic pain were decreased or resolved. After treatment, no serious adverse effects were found on the patients, and there were no adverse effects at all on the infants. Conclusion: The results indicate that oriental treatment can be effective for the management of low back pain and pelvic pain caused by traffic accident during pregnancy. And these treatments are safe to both patients and infants.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.188-195
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• 2007

Purpose: The purpose of this study was to analyze current status of the web-sites dealing with oriental obstetrics & gynecology in the internet, and to evaluate their quality and confidence of health information. Methods: It was selected 54 local sites by searching for such key words as menstrual pain. The evaluation tool consisted of six major classification (Content, Authorship, Purpose, Functionality, Feedback and Privacy). Results: In the evaluation of web-sites, the lowest and the highest scores were 7 and 19 out of 26, and the average score was 13.94. The scores of Purpose, Content, Feedback were higher than the average, but the scores of Authorship, Functionality, Privacy were lower than the average. Conclusion: There is a need to develop a high-quality information about latest, confidence, authorship of documents, and to prevent a exposure of privacy.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.57-70
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• 2010

Purpose: In this study, we investigated the effects of GDB(Gidaebang) on the immune response to establish the treatment mechanism of vaginitis. Methods: We examined the effects of GDB on the DCs(Dendritic cells) phenotypic and functional maturation. iDCs were cultured in the presence of GM-CSF and the generated iDCs were respectively stimulated by GDB or LPS as the control group for 24 hours. To evaluate the DCs phenotypic and functional maturation, we used flow cytometric analysis, RT-PCR and ELISA. Results: 1. GDB upregulated the expression of class II MHC and CD40 on DCs. 2. GDB upregulated the expression of CD80 and CD86 on DCs. 3. GDB induced cytokine IL-12 production and mRNA expression in DCs. Conclusion: These results suggest that GDB is able to improve the antigen-presenting capacity of DCs through the upregulation of their maturation, and might induce proliferation of T cells. In conclusion, this immunomodulatory properties of GDB may be useful in the treatment of vaginitis.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.2
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• pp.154-160
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• 2010

Purpose: This study was done to report the progress of treatment with oriental medicine on a woman who complained of irregular menstruation in menopausal transition. Methods: The patient in this case was treated with Chokyungjongoktanggamibang, acupuncture and moxibustion. And to assess the effectiveness of this treatment, we evaluated the ovarian function by using hormone assay. Results: During treatment period the patient had three times of uterine bleeding, two of the three seemed like normal menstrual bleeding. And analyzing the hormone assay, estraiol level was increased and FSH, LH levels were decreased significantly. However a month after treatment end, estradiol level was decreased and FSH, LH levels were incresead as the levels in menopausal transition or menopause state. And the patient had no more uterine bleeding since last one according to follow up by phone-call. Conclusion: In this study, the progress of ovarian function was specified with hormonal changes after treatment of oriental medicine during menopausal transition. And further studies are needed to find the more appropriate clinical approach for women in menopausal transition.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.3
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• pp.137-154
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• 2007

Purpose: The purpose of this study was to investigate Minnesota Multiphasic Personality Inventory on clinical scales and personality scales of dysmenorrhea patients. Methods : 29 dysmenorrhea patients were tested by MMPI and QSCC II. It is analyzed by one-way ANOVA, Crosstabulation, t-test, and by Duncan method in case of significant difference. Results and Conclusion : 1. The MMPI scores of dysmenorrhea patients were normal range that was elevated in Hs, Hy clinical scales, 1-3 profile type which is profile of conversional neurosis. 2. All of the profiles can be classified three types of profile. Group 1(44.8%) showed a normal profile. Group 2(20.7%) showed a normal profile but elevated in Mf, Ma scales, suggesting mainly extroverted and psychopathic personality. Group 3(34.5%) showed 1-3 profile type which is profile of conversional neurosis. 3. MDQ score and age of dysmenorrhea patients are related to personality in MMPI profile of dysmenorrhea patients.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.3
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• pp.14-25
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• 2010

Purpose: The purpose of this study is to investigate inhibitory effect on the maturation of dendritic cells from aqueous extract from Nardostachys Jatamansi(NJ). Methods: I examined the phenotypic maturation(class II MHC, CD40, CD86), expression of pro-inflammatory cytokine(TNF-$\alpha$, IL-6, IL-12) and endocytosis of FITC-Dextran in the LPS-induced bone marrow-derived dendritic cells(BMDCs) of mice. Furthermore, the Western-blot analysis reveals the mechanism of inhibitory effect. Results: 1. The NJ extract inhibited the phenotypic maturation of BMDCs in a dose-dependent manner. 2. The NJ extract inhibited the LPS induced cytokine production of BMDCs in a dose-dependent manner. 3. The NJ extract enhanced the endocytosis of Dex-FITC in LPS treated DC. 4. The NJ extract inhibited the activation of JNK and p38 phosphorylation, but not ERK phosphorylation of MAPK family and doesn't inhibit Ik-Ba degradation in LPS-stimulated BMDCs. Conclusion: These results suggest that NJ extract is able to attenuate the inflammation and maturation in BMDCs and may inhibit proliferation of T cells. In conclusion, this experiment suggests that NJ extract may be useful in hypersensitivity disease including autoimmune disease.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.2
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• pp.138-147
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• 2019

Objectives: This study was to report clinical effect and safety of Traditional Korean Medical Treatment including Hwangryunhaedok-tang Pharmacopuncture for pregnant woman with low back pain with sciatica. Methods: The patient who suffered from sudden low back pain with sciatica was treated with Hwangryunhaedok-tang Pharmacopuncture, acupuncture, moxibustion, herbal medication and cupping therapy during admission. Visual Analog Score (VAS), Oswestry Disability Index (ODI), McGill pain questionnaire-short form (SF-MPQ) were checked to measure the outcome. Results: After treatment, Visual Analog Score (VAS), Oswestry disability index (ODI), McGill pain questionnaire-short form (SF-MPQ) were considerably improved in this case. Conclusions: The results indicate that Traditional Korean Medical Treatment including Hwangryunhaedok-tang Pharmacopuncture is the effective therapy for low back pain with sciatica during pregnancy.