• Journal of Life Science
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• v.25 no.8
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• pp.953-959
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• 2015

Optogenetics is the combination of optical and molecular strategies to control designated molecular and cellular activities in living tissues and cells using genetically encoded light-sensitive proteins. It involves the use of light to rapidly gate the membrane channels that allows for ion movement. Optogenetics began with the placing of light-sensitive proteins from green algae inside specific types of brain cells. The cells can then be turned on or off with pulses of blue and yellow light. Using the naturally occurring algal protein Channelrhodopsin-2 (ChR2), a rapidly gated light-sensitive cation channel, the number and frequency of action potentials can be controlled. The ChR2 provides a way to manipulate a single type of neuron while affecting no others, an unprecedented specificity. This technology allows the use of light to alter neural processing at the level of single spikes and synaptic events, yielding a widely applicable tool for neuroscientists and biomedical engineers. An improbable combination of green algae, lasers, gene therapy and fiber optics made it possible to map neural circuits deep inside the brain with a precision that has never been possible before. This will help identify the causes of disorders like depression, anxiety, schizophrenia, addiction, sleep disorder, and autism. Optogenetics could improve upon existing implanted devices that are used to treat Parkinson’s disease, obsessive-compulsive disorder and other ailments with pulses of electricity. An optogenetics device could hit more specific subsets of brain cells than those devices can. Applications of optogenetic tools in nonneuronal cells are on the rise.

• The Journal of the Korea institute of electronic communication sciences
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• v.7 no.5
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• pp.1221-1228
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• 2012

This study was carried out in order to offer basic data for preventing halitosis by understanding about the factors related to self-awareness of halitosis and about the relationship with stress and compulsion targeting students for the Department of Dental Hygiene. As a result of research, the whole subjects were indicated to be 1.76 points for the mean in stress, 1.62 points for the mean in compulsion, and 1.84 points for the mean in self-awareness of halitosis. The group of feeling the tongue to be white and the inside of the mouth to be sticky in own symptom inside the mouth was indicated to be 2.02 points(p=0.000) for stress and 2.00 points(p=0.000) for self-awareness of halitosis. The group of often feeling a sense of oral dryness was indicated to be 2.23 points(p=0.000) for stress, 1.95 points(p=0.000) for compulsion, and 1.89 points(p=0.046) for self-awareness of halitosis. The self-awareness of halitosis stood at r=0.133 with compulsion, thereby having indicated slight positive correlation. Stress and compulsion showed high positive correlation with r=0.425. Accordingly, there is a need of infusing recognition through steady education as a dental hygienist who will have interest in emotional factor along with grasping diverse causes for halitosis, and who will be in charge of a future patients' halitosis.

• Journal of Preventive Medicine and Public Health
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• v.28 no.2 s.50
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• pp.433-449
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• 1995

The study subjects in this study are 295 workers who work on one electronics industry, and they were composed of 93 VDT and 202 non-VDT workers. This study was carried out to obtain the prevalence of subjective symptoms and to compare psychological symptom scores from SCL-90-R between VDT and non-VDT work groups. And to verify the relationship between VDT work related symptoms and psychological symptoms, the author compared SCL-90-R T scores between symptom complaining and non-complaining groups. The results are summarized as follows : 1. Throughout the prevalence study of VDT work related symptoms according to VDT work state, the author could select the final 10 symptoms by sex;'eye fatigue', 'foggy vision', 'neck discomfort or pain', 'shoulder discomfort and pain', 'light headedness', 'dizziness', 'acne', 'itching sensation on face', 'difficulty in concentration', 'memory disturbance' in males, and 'blurred vision', 'foggy vision', 'neck discomfort or pain', 'shoulder discomfort and pain', 'abdominal distention', 'indigestion', 'acne', 'prickling sensation on face', 'difficulty in concentration', 'memory disturbance' in females. 2. Throughout comparison of psychological symptom scores from SCL-90-R between VDT and non-VDT workers, except 'Interpersonal sensitivity' in female, Mean T score were higher in VDT workers, but not significantly different between the two groups. These results indicate that the relation between VDT work status and psychological symptoms are not strongly correlated. 3. Because of the nonspecific characteristics of VDT work related symptoms, from the 40 subjective symptoms, the author selected the final 10 symptoms by sex, especially correlated to VDT, and divided the study subjects into symptom complaining and non-complaining groups. The mean SCL-90-R T scores between the two groups were compared. Except for the opthalmologic symptoms in females, the scores were significantly different between the two groups in all symptoms. And this indicates that the VDT work related symptoms strongly correlated with the present individual psychological conditions. 4. Due to understand that which of the 9 psychological symptom dimensions are strongly correlated with the subjective symptoms, the author excuted muliple logistic regression analysis, and the result were as follows; 'depression' and 'somatization', in male, and 'obsessive-compulsive' and 'somatization' in female.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.304-314
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• 2020

This cross-sectional descriptive study investigated the influence of romantic relationships' characteristics, self-esteem and sexual autonomy on limerence in dating relationships among female college students who had or were currently engaged in a dating relationship. The data was collected through self-reported structured questionnaires from 167 female Korean college students using convenient sampling methods from November 25, 2012 to December 20, 2012. The data was analyzed using t-tests, one-way analyses of variance, Scheffe's test, Pearson's correlation coefficients, and multiple linear regression analysis with the IBM SPSS 23.0 program. The results showed that a significant difference was found in limerence according to the frequency of experiencing romantic breakup (F=4.16, p=.003), and limerence in dating relationships was negatively correlated with self-esteem (r=-.31, p<.001) and sexual autonomy (r=-.21, p=.006). Self-esteem and the frequency of romantic breakups explained 20% of limerence in dating relationships among the participants (F=8.03, p<.001). Therefore, as a strategy to solve the problems related to limerence during the period of dating, cognitive and educational interventions are needed to strengthen the self-esteem and sexual autonomy of college students who have had a high number of separations. In addition, early screening of college students with risk factors for limerence and providing problem-solving based counseling will help improve their psychological health.

• Korean Journal of Psychosomatic Medicine
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• v.6 no.2
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• pp.147-154
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• 1998

Objective : This study was designed to find the characteristics of MMPI that could influence the outcome of cognitive behavioral therapy(CBT) for panic disorder. Methods : 34 patients who met DSM-IV criteria for panic disorder with or without agoraphobia had completed 11 weekly sessions of cognitive behavioral therapy. All the patients were assessed with MMPI before the initiation of treatment. Five self-report measures including Beck Depression Inventory(BDI), Spielberger State-Trait Anxiety Inventory(STAI), Agoraphobic Cognition Questionnarie(ACQ), Body Sensation Questionnaire(BSQ), and Daily Anxiety Selfrating (0 - 8 scales) were also assessed as a pre- and post-treatment assessment. After the completion of treatment, patients were classified by the High End-State(HES) functioning group and the Low End-State(LES) functioning group for the data analysis. Results : 1) The LES group showed significantly higher scores in Hypochondriasis Scale(HS), Depression Scale(D), Hysterical Scale(Hy), Obsessive Scale(Pt), Schizophrenia Scale(Sc) and Validity Scale(F) of MMPI than the HES group. However, these differences gave impressions that the LES group had more severe symptoms rather than that they could be the factors influencing the outcome of CBT. 2) Though, the severity of symptoms of the LES group in the 5 measures of pre-assessment was basically higher than that of the HES group. The fact that both group showed the similar improvement between pre- and post-assessment supported the above interpretation. Conclusion : In regarding the above results, MMPI was not a proper tool that could provide the factors influencing the outcome of CBT. In the future study, the authors need to use a different tool that can find the personality characteristics more directly.

• Korean Journal of Psychosomatic Medicine
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• v.7 no.2
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• pp.233-240
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• 1999

The purpose of this study was to make a comparison in perceived stressor and psychopathology among premenstrual, menstrual and postmenstrual phases, in high school girls. Three hundred forty-one high school girls(164 academic school girls, 177 art school girls) participated in this study. Global assessment of recent stress(GARS) scale and symptom checklist-90-revised(SCL-90R) were used to measure perceived stressors and psychopathology. The scores of perceived stressor relevant to change in relationships were significantly higher during the premenstrual and the postmenstrual phases than during the menstrual phase. However, no significant differences were found in psychopathology among three mentstrual phases. Scores of perceived stressor relevant to change or no change in routine were significantly higher in academic school girls than in art school girls. The scores of obsessive-compulsion subscale and positive symptom total were significantly higher in academic school girls than in art school girls. In conclusion, a perceived stressor was higher during the premenstrual and the postmenstrual phases than during the menstrual phase in adolescents, but psychopathology was not related to the menstrual cycle. These results indicated that the psychopathology in adolescent girls might be influenced by other factors than menstrual cycle.

• Proceedings of the Mineralogical Society of Korea Conference
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• 2002.10a
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• pp.53-67
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• 2002

As in the past, we are concerned today with the magnitudes of mineral resources and the adequacy of these resources to meet future needs. In looking at global resource issues, we should consider the need for the resource, its supply, and the environmental consequences of using it. The need for a resource can become a resource dependency, especially as the global population expands and each of us becomes increasingly dependent upon hundreds of natural materials. Therefore, our great mineral consumption makes the human population a true 'Geologic Force', which will be even more significant in the future when the global population is projected to reach alarming proportions. Although our supplies of mineral resources probably will be sufficient for the 21s1 century, the uneven distribution of minerals in the Earth's crust almost certainly will continue to be a major problem The most likely result will be major shifts in both prices and sources of supply of many mineral resources. As for energy resources, we must avoid an obsessive dependency on one fuel and expand instead to thor energy resources. Finally, because the use of resources affects the environment, we need to focus on resource exploitation and global pollution, particularly in regard to ground water and arable land. We must manage our resources so as to be in balance with our environment. And the accelerated industrialization of South Korean economy over the last three decades has resulted in the mass consumption of nuneral commodities. South Korea has around 50 useful mineral commodities for the mineral industry, among 330 kinds of minerals described. The component ratio of the mining industry sector of the gross national production(GNP) in South Korea dropped from $1.2\%\;in\;1971\;to\;0.34\%$ in 1997 due to the rapid growth of other industries In the countxy. During the period from 1971 to 1997, the average growth rate of mineral consumption in South Korea was $9.13\%$ yearly and that of GNP per capita was $14.97\%$. The mineral consumptions per capita showed a continual Increase during the last 30 years as follows(parenthesis. GNP per capita): 0.99 metric tons in 1971($\$289$), 3.83 metric tons in 1989($\$5,210$), 6.11 metric tons in 1995 ($\$10,037$), and 6.66 metric tons in 1997($9,511). The total amount of mineral consumption in South Korea was 33 million tons of 32 mineral commodities in 1971, and 306 million metric tons of 47 mineral commodities In 1997.

• Journal of Acupuncture Research
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• v.24 no.6
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• pp.63-68
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• 2007

Objectives : The purpose of this study was designed to estimate the effects of Oriental medical treatment on posttraumatic stress disorder patient due to a series of traffic accidents by using SCL-90-R. Methods : We studied 20 patients who were admitted to Daegu Haany University Oriental Hospital from October2006 to May 2007. Results : 4 symptoms of SCL-90-R, somatization, obsessive-compulsive, depression and anxiety were significantly different when comparing after-treatment with before-treatment. But, 5 symptoms of SCL-90-R, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation and psychoticism showed no difference between after-treatment with, before-treatment measurements. The total impact or SCL-90-R was significant comparing after-treatment with before-treatment measurements. Conclusions : We concluded that there was a significant effectof Oriental medical treatment on posttraumatic stress disorder patients caused by a seriesof traffic accident. However, the findings of this study need to be confirmed in more patients with further studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.12 no.1
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• pp.149-156
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• 2001

After the fact that obsessive-compulsive symptoms or tic symptoms are common in Sydenham's chorea which is a sequale of rheumatic fever produced by group A beta-hemolytic streptococcus was reported, the association between group A beta-hemolytic streptococcus and a subgroup of obsessivecompulsive disorder(OCD) or tic disorder has been attentioned. This subgroup shared a unique clinical course, characterized by an abrupt onset of symptoms and/or dramatic exacerbations. And this subgroup was distinguished by pre-pubertal onset of symptoms, neurological abnormalities(choreiform movements and a unique pattern of motoric hyperactivity), as well as by relapsing and remitting symptom course. Acronym PANDAS(pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection) was used to denote a subgroup of OCD or tic disorder patients with these clinical characteristics. Then, there was a report suggesting that PANDAS category include some of attention-deficit/hyperactivity disorder(ADHD) and were two case reports of anorexia nervosa and body dysmorphic disorder with characteristics of PANDAS. This case is a patient who developed normally until age of 7, but after pharyngeal inflammation with high fever, he showed disturbance of cognition, social relationship, and language and communication, as well as tic symtoms and abnormal movement on face, hand, and foot. We report this case with review of literatures, because we think that this case belongs to the PANDAS category. Based on this observation, we suggest that PANDAS category include some of childhood disintegrative disorder as well as OCD, tic disorder, and ADHD.

• Korean Journal of Social Welfare
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• v.62 no.3
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• pp.271-297
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• 2010

The purpose of this study was to develop the entity theory on the recovering process from gambling addiction. This study focused on "What is the process of getting out of the pit of gambling addiction?" based on grounded theory methodology suggested by Strauss and Corbin(1990). The subjects of this study were 7 male gambling addicts living in Jeonbuk area. As the result of this study, a total of 97 concepts were drawn, which were classified into 28 subcategories and 16 superordinate categories. The results of analyzing the categories by paradigm showed that in the process of overcoming gambling addiction, the casual condition was 'Being cut off money; 'Losing the will', and the contextual condition corresponding to this phenomenon was 'Shame', 'Repent', and 'Wanting to die'. The core phenomenon was 'Giving up the dream of hitting the jackpot'. The intervening condition to boost this core phenomenon was 'Being helped by friends', 'Being supported by the police', 'Being led by the family', and 'Showing the willpower'. The action/interaction strategies were identified as 'Cutting off the flow of funds', 'Overcoming the temptation of gambling', and 'Diverting attention to other things', ending up 'Being conscious of family', 'Growing up', and 'Being free'. The core concept in the process of overcoming the gambling addiction was revealed as 'Being free by giving up the dream of hitting the jackpot'. The process of getting over the gambling addiction was 'The dream of hitting the jackpot being shattered', 'Giving up the dream of hitting the jackpot', 'Getting out of it', and 'Being free'. The study participants were classified into four types; 'Challenging type', 'Enjoying type', 'Showing off type', and 'Obsessive type'. This study was expected to have significance in establishing the first theory in Korea on the recovering process of gambling addict.