• Title/Summary/Keyword: Observational period

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Hypogonadal men with moderate-to-severe lower urinary tract symptoms have a more severe cardiometabolic risk profile and benefit more from testosterone therapy than men with mild lower urinary tract symptoms

  • Saad, Farid;Doros, Gheorghe;Haider, Karim Sultan;Haider, Ahmad
    • Investigative and Clinical Urology
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    • v.59 no.6
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    • pp.399-409
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    • 2018
  • Purpose: To analyze data from an observational, prospective, cumulative registry study in 805 hypogonadal men stratified by mild or moderate-to-severe lower urinary tract symptoms (LUTS) according to International Prostate Symptom Score. Materials and Methods: A total of 412 men underwent testosterone therapy (TTh) with injectable testosterone undecanoate, 393 men served as untreated controls. Measures of urinary function, anthropometric and metabolic parameters were performed at least twice per year. Results: Data from 615 men with mild LUTS (253 treated, 362 untreated) and 190 with moderate-to-severe LUTS (159 treated, 31 untreated) were available. During a follow-up period of 8 years a significant improvement of LUTS was noted for all TTh-patients whereas the control-groups showed deterioration or fluctuation around initial values. Despite advancing age, TTh fully prevented worsening of symptoms. In parallel, a considerable improvement of anthropometric parameters, lipids and glycemic control, blood pressure, C-reactive protein, and quality of life was found. Moderate-to-severe LUTS was associated with worse cardiometabolic risk profile at baseline as well as worse cardiovascular outcomes during follow-up in comparison to mild LUTS. Effect size of TTh was more pronounced in men with moderate-to-severe than with mild LUTS. Conclusions: Correcting hypogonadism by TTh is highly effective and safe for improving LUTS in hypogonadal men. TTh may also improve cardiometabolic risk and major adverse cardiovascular events.

Investigation of surface homogeneity of (3200) Phaethon

  • Lee, Hee-Jae;Kim, Myung-Jin;Kim, Dong-Heun;Moon, Hong-Kyu;Choi, Young-Jun;Kim, Chun-Hwey;Lee, Byeong-Cheol;Yoshida, Fumi;Roh, Dong-Goo;Seo, Haingja
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.45.1-45.1
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    • 2018
  • We present observational evidence of the surface homogeneity on Phaethon based on the time-series multi-band photometry and spectrometry. The observations of Phaethon were conducted in Nov.-Dec. 2017. We confirmed that Phaethon is a B-type asteroid, as was previously known, and its rotational color variation was not detected. During our observation period, the sub-solar latitude of this asteroid was approximately $55^{\circ}S$, corresponding to the southern hemisphere of the body. Thus, we found that the southern hemisphere of Phaethon has a homogeneous surface from our observation results. In addition, we compared our spectra with archival data to investigate the latitudinal surface properties of the asteroid. The result showed that it doesn't have a latitudinal color variation. To verify this assumption, we investigated its solar-radiation heating effect, and the result suggested that this asteroid underwent a uniform thermal metamorphism regardless of latitude, which is consistent with our observations. Based on this result, we discuss the homogeneity of the surface of the body.

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Types of injuries caused by isolated electric scooter accidents

  • Kyongwon, Yoo;Hyung Il, Kim
    • Journal of Trauma and Injury
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    • v.35 no.4
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    • pp.232-239
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    • 2022
  • Purpose: The recent increase in electric scooter (e-scooter) use has been accompanied by an increase in injuries from e-scooter-related accidents. Studies have reported that most such injuries are minor, and physicians may therefore underestimate the severity of such injuries. This study investigated the types and severity of injuries caused by isolated e-scooter accidents (i.e., those that did not involve colliding with other cars or falling from heights). Methods: This prospective observational study was conducted from May to December 2021 at Dankook University Hospital tertiary medical center. The demographic data of patients injured in isolated e-scooter-related accidents were collected. All injuries were categorized by body part. Results: Fifty eligible patients visited our emergency department during the study period. Of these, 76% were categorized as nonemergency, and 62% were discharged after initial evaluation and treatment at the emergency department. Another 10% were admitted to the intensive care unit (ICU) and 18% to the ward, with nine patients receiving at least one operation. The average hospital stays were 2.4 days in the ICU and 9 days in the ward. One death occurred due to traumatic brain injury (overall mortality rate, 2%). Multiple fractures of the left third through ninth ribs combined with lung laceration and fractures of T12 and L4 were noted. Conclusions: Various types and severities of injuries can occur in isolated e-scooter accidents. While most such injuries are minor, some will require ICU admission or surgery, and deaths can occur. Physicians should not underestimate the severity of such injuries.

A Comprehensive Approach to Posttraumatic Lymphedema Surgical Treatment

  • Nicolas Pereira;Vanessa Onate;Ricardo Roa
    • Archives of Plastic Surgery
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    • v.50 no.4
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    • pp.422-431
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    • 2023
  • Background Posttraumatic lymphedema (PTL) is sparsely described in the literature. The aim of this study is to propose a comprehensive approach for prevention and treatment of PTL using lymphovenous anastomosis (LVA) and lymphatic vessels free flap, reporting our experience in the management of early-stage lymphedema. Methods A retrospective observational study was performed between October 2017 and July 2022. Functional assessment with magnetic resonance lymphangiography and indocyanine green lymphography was performed. Patients with lymphedema and functional lymphatic channels were included. Cases with limited soft tissue damage were proposed for LVA, and those with acute or prior soft tissue damage needing skin reconstruction were proposed for superficial circumflex iliac artery perforator lymphatic vessels free flap (SCIP-LV) to treat or prevent lymphedema. Primary and secondary outcomes were limb volume reduction and quality of life (QoL) improvement, respectively. Follow-up was at least 1 year. Results Twenty-eight patients were operated using this approach during the study period. LVA were performed in 12 patients; mean reduction of excess volume (REV) was 58.82% and the improvement in QoL was 49.25%. SCIP-LV was performed in seven patients with no flap failure; mean REV was 58.77% and the improvement QoL was 50.9%. Nine patients with acute injury in lymphatic critical areas were reconstructed with SCIP-LV as a preventive approach and no lymphedema was detected. Conclusion Our comprehensive approach provides an organized way to treat patients with PTL, or at risk of developing it, to have satisfactory results and improve their QoL.

A Prospective Observational Study on Symptoms of the Postpartum Women with Korean Medicine Treatment during Six Weeks after Childbirth (한의치료를 받은 산모의 산후 6주간 증상에 대한 전향적 관찰 연구)

  • Kim, Pyung-Wha;Kim, An-Na;Jang, Hyun-Chul;Lee, Eun-Hee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.30 no.4
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    • pp.114-134
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    • 2017
  • Objectives: This study aims to investigate the changes of women's postpartum symptoms, including their weights, edema index and quality of life (QOL) over the first six weeks after childbirth. Methods: The study participants were 31 postpartum women treated in the Dept. of Obstetrics & Gynecology, at Woo-Suk University Korean Medicine Hospital, from May 20th to August 5th, 2016. In the first 2 weeks of the postpartum period, the main data collection method was to interview each patient and write down all of their complaints, and additionally referring to each participant's PHR (Personal Health Records). At the 3rd, 4th, 5th and 6th week, the researcher interviewed participants by phone once a week. The participants' weight, edema index (ECW/TBW) and the quality of life (by EQ-VAS) were measured at 1st and 2nd week after childbirth. And, EQ-VAS was assessed once more at the 6th week after childbirth. As a last step, the participants responded to a survey on satisfaction regarding their postpartum care with Korean Medicine. Results: 1. In the 1st one week after childbirth, edema was the most frequent complaint. It was about joint pain of the upper limbs in the 2nd and 3rd weeks, sweating in the 4th week, and joint pain of the upper limbs in the 5th and the 6th weeks. 2. In the 1st two weeks of the postpartum period, the weight of the participants decreased from $66.33{\pm}9.30kg$ to $62.60{\pm}8.92kg$ (p<0.001) and the edema index ECW/TBW decreased from $0.399{\pm}0.010$ to $0.385{\pm}0.0 4$ (p<0.001). The EQ-VAS significantly improved from $61.77{\pm}17.72$ to $73.51{\pm}14.67$ (p<0.001). In the last 4-weeks of the postpartum period, the EQ-VAS decreased from $74.30{\pm}14.25$ to $73.63{\pm}13.35$, but this difference was not statistically significant (p=0.749). 3. Regarding the satisfaction with postpartum care with Korean Medicine, 60% of the participants responded that it was 'Excellent' and 40% said it was 'Good'. Conclusion: Over the entire postpartum period, the most frequent complaints were about musculoskeletal symptoms. Postpartum care with Korean Medicine treatments in the early postpartum period improves various postpartum symptoms and the quality of life for postpartum women.

Spatial and temporal distribution of Wind Resources over Korea (한반도 바람자원의 시공간적 분포)

  • Kim, Do-Woo;Byun, Hi-Ryong
    • Atmosphere
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    • v.18 no.3
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    • pp.171-182
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    • 2008
  • In this study, we analyzed the spatial and temporal distribution of wind resources over Korea based on hourly observational data recorded over a period of 5 years from 457 stations belonging to Korea Meteorological Administration (KMA). The surface and 850 hPa wind data obtained from the Korea Local Analysis and Prediction System (KLAPS) and the Regional Data Assimilation and Prediction System (RDAPS) over a period of 1 year are used as supplementary data sources. Wind speed is generally high over seashores, mountains, and islands. In 62 (13.5%) stations, mean wind speeds for 5 years are greater than $3ms^{-1}$. The effects of seasonal wind, land-sea breeze, and mountain-valley winds on wind resources over Korea are evaluated as follows: First, wind is weak during summer, particularly over the Sobaek Mountains. However, over the coastal region of the Gyeongnam-province, strong southwesterly winds are observed during summer owing to monsoon currents. Second, the wind speed decreases during night-time, particularly over the west coast, where the direction of the land breeze is opposite to that of the large-scale westerlies. Third, winds are not always strong over seashores and highly elevated areas. The wind speed is weaker over the seashore of the Gyeonggi-province than over the other seashores. High wind speed has been observed only at 5 stations out of the 22 high-altitude stations. Detailed information on the wind resources conditions at the 21 stations (15 inland stations and 6 island stations) with high wind speed in Korea, such as the mean wind speed, frequency of wind speed available (WSA) for electricity generation, shape and scale parameters of Weibull distribution, constancy of wind direction, and wind power density (WPD), have also been provided. Among total stations in Korea, the best possible wind resources for electricity generation are available at Gosan in Jeju Island (mean wind speed: $7.77ms^{-1}$, WSA: 92.6%, WPD: $683.9Wm^{-2}$) and at Mt. Gudeok in Busan (mean wind speed: $5.66ms^{-1}$, WSA: 91.0%, WPD: $215.7Wm^{-2}$).

Vertical Structures of Temperature and Ozone Changes in the Stratosphere and Mesosphere during Stratospheric Sudden Warmings

  • Kim, Jeong-Han;Jee, Geonhwa;Choi, Hyesun;Kim, Baek-Min;Kim, Seong-Joong
    • Journal of Astronomy and Space Sciences
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    • v.37 no.1
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    • pp.69-75
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    • 2020
  • We analyze the observations of temperature and ozone measured by the Microwave Limb Sounder (MLS) during the period of 2005-2016, to investigate the vertical structures of temperature and ozone in the stratosphere and mesosphere during stratospheric sudden warming (SSW). We compute the height profiles of the correlation coefficients between 55 height levels of MLS temperature anomalies and compare them with the results of Whole Atmosphere Community Climate Model simulations for three major SSWs. We also construct the temperature and ozone anomalies for the events to investigate the changes in the temperature and ozone distributions with height. There seems to always be a relatively weak but broad negative correlation between the temperature anomaly at 10 hPa and temperature anomalies over the entire mesosphere during the period before SSW events. However, this pattern gets stronger in the lower mesosphere but becomes a positive correlation in the upper mesosphere and lower thermosphere after the onset of SSW. We also found that the temperatures from the simulations show a similar trend to the observational results but with smaller variations and the transition height from negative to positive correlation in the mesosphere is much lower in the simulation than in the actual observations.

16 Cases of Anti-obesity Drug Intoxication Experienced in 4 Emergency Departments (4개 응급센터에 내원한 비만치료제 중독 환자들의 다양한 임상양상 경험: 16례)

  • Han, Sung Hoon;So, Byung Hak;Jung, Won Joong;Kim, Hyung Min
    • Journal of The Korean Society of Clinical Toxicology
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    • v.10 no.2
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    • pp.111-117
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    • 2012
  • Purpose: In Korea, few studies have examined the acute toxicity of anti-obesity drugs. The purpose of this study is to analyze the general characteristics and clinical aspect of acute anti-obesity drug intoxication. Methods: We retrospectively investigated patients admitted to the emergency department after anti-obesity drug intoxication between March, 2004 and February, 2012. The medical records of these patients were reviewed for demographic data, toxicologic history, time elapsed to presentation, clinical symptoms and signs, treatment, and outcome. Results: There were a total of 18 anti-obesity intoxication cases during the study period; of 16 which were included in our study. The purchasing route of the anti-obesity drug was mainly through a doctor's prescription (68.8%), however, some were obtained through the internet and the pharmacies. The mean time to The most commonly ingested antiobesity drug was sibutramine (31.3%) and many of the cases (62.5%) were multi-drug ingestions. The most common clinical manifestations were gastrointestinal symptoms (94%), but, CNS symptoms (75%) and cardiovascular symptoms (75%) were almost equally present. 13 patients (81%) were discharged after clearance of toxic symptoms and signs with a mean observational period of 7.0 hours. 3 patients were admitted for observation and treatment; of which 1 patient died due to fatal complications. Conclusion: Most anti-obesity intoxications show mild toxicity and a nonfatal clinical course. However, the recent trend toward prescribing psychostimulant anti-obesity medication, which can be fatal after an acute overdose, calls physicians' attention to treating of anti-obesity intoxications.

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The Study on Relation between Implementation of Six Sigma Quality Management and Financial Performance using Propensity Score Matching (식스 시그마 품질경영활동이 기업의 재무적 성과지표에 미치는 영향연구: 경향점수매칭을 이용하여)

  • Park, Byounghwa;Park, Taeyoung;Park, Minjae
    • Journal of Korean Society for Quality Management
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    • v.44 no.2
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    • pp.341-356
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    • 2016
  • Purpose: The purpose of this paper is to study whether the adoption of Six Sigma quality management by a firm positively affects its financial performance. The correlation between the duration of Six Sigma implementation period and the financial status of the firm is investigated as well. Methods: We conduct the analysis using data from Manufacturing Industry Productivity Panel Survey 2013 provided by Korea Productivity Center and Ministry of Trade, Industry and Energy. Propensity score matching is used to reduce sample selection bias of observational study. Furthermore, we use multiple linear regression in order to study the relationship between the implementation of Six Sigma quality management and financial performance. The return on assets and ratio of net income to net sales are considered as dependent variable and implementation of Six Sigma as independent variable. Results: The indication of this analysis is that implementation of Six Sigma quality management does not significantly enhance financial status. The firms that adopted Six Sigma quality management were categorized into three groups according to the implementation period. Comparison of each group with the firms that do not adopt Six Sigma quality management does not show statistically significant enhancement of financial status. Conclusion: In conclusion, both adoption and duration of six sigma quality management do not affect financial performance significantly.

Spatial Distribution Characteristics of Wind Map over Korea Using Meteorological Resources (기상정보를 활용한 한반도 풍력자원지도 공간적 분포 특성)

  • Heo, Cheol-Un;Lee, YongSeob;Lee, Eun-Jeong
    • Atmosphere
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    • v.20 no.2
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    • pp.63-71
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    • 2010
  • In this study, we derived the wind speed at 50 m and 80 m above sea level from 567 stations over a period of 1 year and correlated to measured wind speed at 5 radiosonde sites. From these correlations, we derived and analyzed the spatial distribution of wind map over Korea based on hourly observational data recorded over a period of 5 years from 2004 to 2008. As a results, wind speed is generally high over seashores, mountains, and islands. Mean wind speed over Korea at 50 and 80 m above sea level for 5 years during 2004 to 2008 seasonally are highest at Spring, and then followed by Winter, Fall, and Summer. In 76 (14%) stations, mean wind speed at 80 m above sea level for 5 years during 2004 to 2008 are greater than $5ms^{-1}$. The prevailing winds over Korea at 80 m above sea level for 5 years during 2004 to 2008 are North (44%), Northwest (16%), and West (15%). In 99 stations, the % of wind faster than $5ms^{-1}$ was higher than 40%, and in 62 stations, the % of wind faster than $5ms^{-1}$ was higher than 50%. In 178 station, the % of prevailing winds was higher than 30%, and there are 7 stations which also have wind speeds over $5ms^{-1}$, ranking from highest to lowest, Dongsong, Daegwallyeong, Baekun Mt., Hyangrobong Mt., Sorak Mt., Gosan, and Misiryeong Mt..